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Paeds Casesneurology-neurodisability-and-neuromuscular

Paeds Cases · neurology-neurodisability-and-neuromuscular

Counsel a family on starting levetiracetam for newly diagnosed focal epilepsy — OSCE

OSCE communication and shared decision-making station: explaining the selection, titration and adverse-effect monitoring of levetiracetam to the family of a ten-year-old boy with newly diagnosed focal epilepsy, addressing the behavioural adverse effects, the favourable interaction profile, the monitoring schedule, and the principle of syndrome-driven selection in plain language.

osce communication and shared decision-making
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Target exams

MRCPCH ClinicalRACP DCERCPSC Pediatrics

Target exams

MRCPCH ClinicalRACP DCERCPSC Pediatrics
Prompt
A ten-year-old boy and his parents are in clinic after a diagnosis of focal epilepsy confirmed by EEG and MRI. The paediatrician has recommended levetiracetam as the first-choice medicine. The parents have read online that epilepsy medicines cause rashes, liver damage and behaviour problems, and they want to know why this particular drug was chosen, what to watch for, and whether the uncle's carbamazepine would be simpler. Counsel them.

Candidate brief

You have eight minutes to counsel the parents of a ten-year-old boy with newly diagnosed focal epilepsy, confirmed by EEG and MRI, for whom levetiracetam has been recommended as the first-choice medicine. Use a structured, honest, empathic approach that explains why this drug was selected, addresses the online fears, outlines the adverse effects to watch for, and builds a shared monitoring plan. [1] [5]

Key teaching and communication objectives

Acknowledge and validate the family's concern before delivering information, and allow silence. Explain in plain language that levetiracetam was chosen because it is effective for this type of epilepsy, because a large trial showed it was as good as the older medicines with fewer side effects, and because it does not interact with other medicines or with the body's enzyme systems the way some of the older drugs do. Reassure them that it does not cause rashes or liver damage at the rates that the older drugs do, which is one of the reasons it was chosen. [1] [9]

Address the behavioural side effect directly. Explain that levetiracetam can cause irritability or mood changes in roughly one child in ten, usually in the first few weeks, and that it is often manageable by adjusting the dose. Tell the parents to contact the team if they notice any change in behaviour, and explain that an alternative can be used if the effect does not settle. Frame this as a known, watched-for and manageable effect, not as a reason to avoid the drug. [5]

Explain why the uncle's carbamazepine is not the best choice for this child, even though it is also used for focal epilepsy. Explain that the medicine is chosen for the individual child's type of epilepsy, that carbamazepine can cause rashes, low sodium and blood-count changes that need monitoring, and that it interacts with other medicines. Reassure them that the choice was made with their child's specific situation in mind. [1] [5]

Close with a shared plan that includes the titration schedule, the follow-up appointment, a seizure action plan for school, and a clear point of contact for questions or concerns. Reassure the family that the goal is not just seizure freedom but also keeping the child functioning at their best at school and at home. [9] [5]

References

  1. [1]Glauser T, Ben-Menachem E, Bourgeois B, et al. Updated ILAE evidence review of antiepileptic drug efficacy and effectiveness as initial monotherapy for epileptic seizures and syndromes. Epilepsia, 2013.PMID 23350722
  2. [5]Perucca P, Gilliam FG. Adverse effects of antiepileptic drugs. Lancet Neurol, 2012.PMID 22832500
  3. [9]Jones KEA, Howells R, Mallick AA, et al. NICE guideline review: Epilepsies in children, young people and adults NG217. Arch Dis Child Educ Pract Ed, 2023.PMID 37339862