Paeds Cases · infectious-diseases
Prolonged fever in a returned traveller — communication OSCE
OSCE on counselling a family through a suspected diagnosis of extensively drug-resistant enteric fever: blood culture before antibiotics, antibiotic stewardship, safety-netting for complications, and vaccine and public-health follow-up.
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Target exams
Objectives
- Establish that the stepwise fever after travel to Pakistan makes enteric fever the leading diagnosis. [1]
- Explain why blood culture must be taken before antibiotics, without dismissing the parents' wish to start treatment. [1]
- Counsel on XDR-aware empiric therapy and antibiotic stewardship in plain language. [8] [4]
- Safety-net for the danger windows: perforation in weeks 3-4 and the red-flag abdomen. [1]
- Outline public-health notification, exclusion and the typhoid conjugate vaccine for the family and future travel. [14]
Candidate brief
Twelve-minute station. Both parents are present and anxious; they have read about typhoid online and want immediate antibiotics. The child is alert but febrile at 39.4 degrees with a soft, mildly tender abdomen and no peritonism. Blood culture has not yet been taken. [1]
Expected actions
- Acknowledge the parents' worry and validate that enteric fever is a real possibility worth acting on. [1]
- Explain in plain language that the single most useful test is a blood culture, and that it must be drawn before antibiotics so we can identify the organism and choose the right drug. [1]
- Name the XDR concern from Pakistan travel honestly, and reassure that we have effective options (azithromycin first, with stronger drugs held in reserve). [8]
- Take the blood culture, start empiric azithromycin after it is drawn, and explain the plan to narrow once the laboratory returns susceptibilities. [4]
- Give clear, written safety-netting: return immediately for severe abdominal pain, a hard or rigid abdomen, vomiting blood or black stools, drowsiness, or worsening fever. [1]
- Explain that enteric fever is notifiable, that the child should stay off school until cleared, and that the typhoid conjugate vaccine protects future travel and close contacts. [14]
Marking
Pass: validates concern; insists on blood culture before antibiotics; explains XDR and stewardship in plain language; clear safety-netting for perforation; public-health and vaccine plan. [1] [4] [14] Fail: starts antibiotics before culture; dismisses parents; no XDR reasoning; rigid abdomen missed or attributed to gastro; no notification, exclusion or vaccine discussion. [8]
References
- [1]Wain J, Hendriksen RS, Mikoleit ML, Keddy KH, Ochiai RL, Typhi G Typhoid fever Lancet (London, England), 2015.PMID 25458731
- [4]Parry CM, Qamar FN, Rijal S, McCann N What should we be recommending for the treatment of enteric fever? Open Forum Infectious Diseases, 2023.PMID 37274536
- [8]Carey ME, Dyson ZA, Ingle DJ, Amir A, Baker S, Holt KE Global diversity and antimicrobial resistance of typhoid fever pathogens: insights from a meta-analysis of 13,000 Salmonella Typhi genomes eLife, 2023.PMID 37697804
- [14]Bhutta ZA International travel and the risk of extensively drug-resistant typhoid: issues and potential solutions Clinical Infectious Diseases, 2021.PMID 32609356