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Paeds SAQsrespiratory-sleep-and-airway

Paeds SAQs · respiratory-sleep-and-airway

Chronic cough in children — short-answer question

Short-answer question on the definition, classification by cough quality, specific-cough pointers, and the antibiotic-first management of chronic wet cough in children.

20 marks30 min
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Target exams

RACP DWEMRCPCH TheoryABP General Pediatrics

Target exams

RACP DWEMRCPCH TheoryABP General Pediatrics
Prompt
A 4-year-old girl is referred with a daily cough present for seven weeks. The cough sounds wet and rattly and has never fully cleared since a cold two months ago. She is thriving, has no digital clubbing, and her chest examination and chest X-ray are normal. She has already completed two courses of inhaled salbutamol with no benefit. Outline your definition of chronic cough, how you classify it, the pointers you would seek, and your management plan including any drug treatment.

Part A — Definition, classification and pointers (10 marks)

a) Define chronic cough in children and state the diagnostic branch point (3 marks)

Chronic cough in a child is a daily cough persisting for more than four weeks — deliberately shorter than the eight-week adult threshold, because a child still coughing at a month usually has an identifiable, treatable cause rather than a viral tail. The first and most powerful classifying step is to decide whether the cough is wet or dry. [1]

b) Explain the classification by cough quality and by specific pointers (4 marks)

A wet or productive cough implies excessive airway secretions and suppurative disease, whereas a dry cough points to airway irritation or a sensitised reflex. The second axis is specific versus non-specific: a specific cough carries a pointer to underlying disease, while a non-specific cough is a dry cough in a well, thriving child with a normal examination and chest X-ray. This grid directs whether the child is investigated or observed. [1] [2]

c) List the specific-cough pointers you would seek (3 marks)

Wet or productive cough, cough from birth or the neonatal period, a choking episode suggesting foreign body, failure to thrive, digital clubbing, chest-wall deformity, exertional dyspnoea, haemoptysis, recurrent pneumonia, cardiac signs, and neurodevelopmental disease with aspiration risk. A single positive pointer converts observation into investigation. [1]

Part B — Management (10 marks)

a) Give your working diagnosis and initial management for this wet cough (6 marks)

In a thriving preschool child with an isolated chronic wet cough, no other pointers, and normal baseline tests, the leading diagnosis is protracted bacterial bronchitis. I would treat with a trial of an appropriate oral antibiotic for at least two weeks; amoxicillin-clavulanate has the strongest randomised evidence. Resolution of the cough within this period both treats the child and confirms the diagnosis. I would stop the ineffective salbutamol and counsel against over-the-counter cough medicines, which are ineffective and potentially harmful. [2] [3]

b) Describe your plan if the cough persists after antibiotics (4 marks)

If the cough only partially responds or recurs, I would extend the antibiotic course to four weeks. If it still fails to clear after an adequate course, this is no longer simple protracted bacterial bronchitis and I would escalate: flexible bronchoscopy with bronchoalveolar lavage for microbiology and to exclude a retained foreign body or airway malformation, a chest CT to look for bronchiectasis, and a work-up for cystic fibrosis and immunodeficiency. Persistent wet cough despite treatment has an underlying cause until proven otherwise. [2]

References

  1. [1]Chang AB, Landau LI, Van Asperen PP, et al Cough in children: definitions and clinical evaluation. Med J Aust, 2006.PMID 16618239
  2. [2]Chang AB, Oppenheimer JJ, Weinberger MM, et al Management of Children With Chronic Wet Cough and Protracted Bacterial Bronchitis: CHEST Guideline and Expert Panel Report. Chest, 2017.PMID 28143696
  3. [3]Marchant J, Masters IB, Champion A, et al Randomised controlled trial of amoxycillin clavulanate in children with chronic wet cough. Thorax, 2012.PMID 22628120