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Folio edition · Set in Instrument Serif & Archivo

Paeds SAQspreventive-and-community-paediatrics

Paeds SAQs · preventive-and-community-paediatrics

Immunisation principles and national schedule comparison — formative SAQs

Formative SAQs on immunisation principles.

20 marks30 min
On this page & tools

Target exams

RACP General PaediatricsMRCPCH Theory

Target exams

RACP General PaediatricsMRCPCH Theory
Prompt
Immunisation principles and national schedule comparison

recommendations of the Advisory Committee on Immunization Practices (ACIP)." source: "MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports" year: 2011 url: "https://pubmed.ncbi.nlm.nih.gov/21293327/"

  • id: 5 pmid: 38206855 authors: "Wodi AP" title: "Advisory Committee on Immunization Practices Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger - United States, 2024." source: "MMWR. Morbidity and mortality weekly report" year: 2024 url: "https://pubmed.ncbi.nlm.nih.gov/38206855/"
  • id: 6 pmid: 36757872 authors: "Wodi AP" title: "Advisory Committee on Immunization Practices Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger - United States, 2023." source: "MMWR. Morbidity and mortality weekly report" year: 2023 url: "https://pubmed.ncbi.nlm.nih.gov/36757872/"
  • id: 7 pmid: 33571172 authors: "Wodi AP" title: "Advisory Committee on Immunization Practices Recommended Immunization Schedule for Children and Adolescents Aged 18 Years or Younger - United States, 2021." source: "MMWR. Morbidity and mortality weekly report" year: 2021 url: "https://pubmed.ncbi.nlm.nih.gov/33571172/"
  • id: 8 pmid: 23760231 authors: "McLean HQ" title: "Prevention of measles, rubella, congenital rubella syndrome, and mumps, 2013: summary recommendations of the Advisory Committee on Immunization Practices (ACIP)." source: "MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports" year: 2013 url: "https://pubmed.ncbi.nlm.nih.gov/23760231/"
  • id: 9 pmid: 8440043 authors: "Tulchinsky TH" title: "Measles control in developing and developed countries: the case for a two-dose policy." source: "Bulletin of the World Health Organization" year: 1993 url: "https://pubmed.ncbi.nlm.nih.gov/8440043/"
  • id: 10 pmid: 40185555 authors: "Colburn NE" title: "Measles - Resurgence of an Old Foe." source: "The Medical clinics of North America" year: 2025 url: "https://pubmed.ncbi.nlm.nih.gov/40185555/"
  • id: 11 pmid: 40272967 authors: "Kiang MV" title: "Modeling Reemergence of Vaccine-Eliminated Infectious Diseases Under Declining Vaccination in the US." source: "JAMA" year: 2025 url: "https://pubmed.ncbi.nlm.nih.gov/40272967/"
  • id: 12 pmid: 25037990 authors: "Amirthalingam G" title: "Effectiveness of maternal pertussis vaccination in England: an observational study." source: "Lancet (London, England)" year: 2014 url: "https://pubmed.ncbi.nlm.nih.gov/25037990/"
  • id: 13 pmid: 28468899 authors: "Gkentzi D" title: "Maternal vaccination against pertussis: a systematic review of the recent literature." source: "Archives of disease in childhood. Fetal and neonatal edition" year: 2017 url: "https://pubmed.ncbi.nlm.nih.gov/28468899/" --- [1]

SAQ 1 (10 marks)

Infant immunisation principles. [1]

  1. Conjugate vs polysaccharide. (4) [1]
  2. Valid dose rules. (3) [1]
  3. Visit steps. (3) [1]

Model answer

Conjugate vaccines enable infant memory; plain polysaccharides perform poorly in early infancy. Invalid early doses are not counted. Reconcile history, give due antigens, document, report and recall. [1]

SAQ 2 (10 marks)

Herd immunity and schedule comparison. [1]

  1. Coverage targets. (5) [1]
  2. Cross-national schedule differences. (5) [1]

Model answer

High coverage protects those who cannot be vaccinated. National schedules differ by epidemiology and logistics while sharing core immunology. [1]

References

  1. [1]Fine PE Herd immunity: history, theory, practice Epidemiol Rev, 1993.PMID 8174658
  2. [2]Anderson RM Immunisation and herd immunity Lancet, 1990.PMID 1969023
  3. [3]National Center for Immunization and Respiratory Diseases General recommendations on immunization --- recommendations of the Advisory Committee on Immunization Practices (ACIP) MMWR Recomm Rep, 2011.PMID 21293327