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Folio edition · Set in Instrument Serif & Archivo

Paeds Vivasnephrology-urology-fluids-and-electrolytes

Paeds Vivas · nephrology-urology-fluids-and-electrolytes

Urinalysis, renal function and paediatric kidney assessment — branching viva

Branching viva on bedside Schwartz eGFR calculation and staging, urine collection method, dipstick-versus-sediment interpretation, the creatinine lag, and the transition of estimating equations to adult care.

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Target exams

RACP General PaediatricsRACP DCEMRCPCH ClinicalRCPSC Pediatrics

Target exams

RACP General PaediatricsRACP DCEMRCPCH ClinicalRCPSC Pediatrics
Prompt
You are the paediatric registrar. The examiner will move you through linked kidney-assessment problems: a well child needing an eGFR, a febrile toddler with a bag culture, an oliguric sick child with a normal creatinine, and an adolescent at transfer to adult care.

Station map

Branch A — Well child, calculate the eGFR

Examiner: A 7-year-old is 120 cm tall with a serum creatinine of 0.7 mg per dL on an enzymatic assay. Calculate the estimated GFR and stage it. [1]

Strong answer should include:

  • State the bedside Schwartz equation: eGFR equals 0.413 times height in cm divided by serum creatinine in mg per dL. [1]
  • Arithmetic: 0.413 times 120 divided by 0.7, about 71 mL per min per 1.73 m2. [1]
  • Stage G2 (60 to 89) per KDIGO; note the value is indexed to 1.73 m2. [4]
  • Mention the need for a measured height and the original 0.55 constant being outdated. [1]

Trap: quoting the original 0.55 constant or forgetting to index to 1.73 m2. [1]

Branch B — Febrile toddler with a bag culture

Examiner: An 18-month-old is febrile. The bag-urine culture grows mixed coliforms. Can you treat for urinary tract infection? [3]

Strong answer should include:

  • Bag urine has a high contamination rate; mixed growth usually means skin flora. [3]
  • Use clean-catch, catheterisation or suprapubic aspiration for diagnosis. [3]
  • A reliable-method culture at a significant count with a single organism supports infection. [3]
  • Read dipstick and culture with the clinical picture; a sick febrile child with a weak dipstick still needs a reliable sample. [2]

Trap: treating a contaminated bag culture as disease and creating false diagnostic momentum. [3]

Branch C — Oliguric child, normal creatinine

Examiner: A dehydrated, oliguric 4-year-old has a creatinine within the reference range. The night team plans discharge because the kidneys are fine. [5]

Strong answer should include:

  • Creatinine lags the fall in filtration; a single normal value does not exclude acute kidney injury. [5]
  • Trend the creatinine and the urine output; manage fluid, electrolytes and the cause. [5]
  • Add the urinalysis and microscopy to localise intrinsic versus pre-renal disease. [2]
  • Escalate to nephrology and intensive care if oliguria or potassium climb persist. [4]

Trap: equating one normal number with normal function in a sick child. [5]

Branch D — Adolescent at transition

Examiner: A 17-year-old with stable chronic kidney disease transfers to adult care. The paediatric Schwartz equation is being used. What should change? [6]

Strong answer should include:

  • Agree the equation with the adult team to avoid a jump in the GFR estimate at handover. [6]
  • The Full Age Spectrum or cystatin C-based equations cross the boundary more smoothly. [6]
  • Hand over the trend and the baseline, not only single numbers. [4]
  • Confirm reference intervals used by the adult laboratory. [4]

Trap: carrying a paediatric equation into adult care without confirming continuity. [6]

Closing synthesis the candidate should say

"I collect urine by a method I can trust, read the dipstick against the microscopy, estimate GFR with the bedside Schwartz equation using the 0.413 constant and a measured height, stage with KDIGO, and trend the creatinine. I never let a normal creatinine or a contaminated culture end a high-risk story." [1] [2] [5]

References

  1. [1]Schwartz GJ, et al New equations to estimate GFR in children with CKD J Am Soc Nephrol, 2009.PMID 19158356
  2. [2]Simerville JA, et al Urinalysis: a comprehensive review Am Fam Physician, 2005.PMID 15791892
  3. [3]Whiting P, et al Rapid tests and urine sampling techniques for the diagnosis of urinary tract infection (UTI) in children under five years: a systematic review BMC Pediatr, 2005.PMID 15811182
  4. [4]Stevens PE, et al Evaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guideline Ann Intern Med, 2013.PMID 23732715
  5. [5]Hessey E, et al Evaluation of height-dependent and height-independent methods of estimating baseline serum creatinine in critically ill children Pediatr Nephrol, 2017.PMID 28523356
  6. [6]Pottel H, et al Estimating glomerular filtration rate at the transition from pediatric to adult care Kidney Int, 2019.PMID 30922665