Phys Clinical Cases · oncological
Cancer Cachexia AND Nutritional Support — DCE Clinical Case
DCE long-case and short-case station for Cancer Cachexia AND Nutritional Support.
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Cancer Cachexia AND Nutritional Support — Clinical Case
DCE Long Case
Patient brief
Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Cancer Cachexia AND Nutritional Support. [1]
Presenting complaint: Subacute or acute symptoms referable to Cancer Cachexia AND Nutritional Support, with enough detail to force prioritisation. [1] [2]
Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]
Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]
Examination: Key positives and critical negatives for dangerous differentials. [1]
Investigations: A small set of results that change management. [1] [2]
Tasks
- Present a prioritised problem list. [1]
- Defend investigations and immediate therapy. [1] [2]
- Provide safety-net and follow-up advice. [2]
Model discussion points
- Working diagnosis and acuity. [1]
- Differentials and discriminators. [2]
- Treatment sequence and monitoring. [1] [2] [3]
- Multimorbidity and communication. [2]
Short case
Focused examination or counselling station linked to Cancer Cachexia AND Nutritional Support, with one interpretation task and one shared-decision point. [1] [2]
References
- [1]Liu TK, Noble D, Stares M, Phillips I Identifying markers of cachexia and nutritional deficit on radical radiotherapy outcomes in lung and head and neck cancer Curr Opin Support Palliat Care, 2026.PMID 42421369
- [2]Petersen E, Sheldon J, Torgerson H, Kirschenbaum M, et al. The impact of cachexia and sarcopenia in bladder cancer Curr Opin Support Palliat Care, 2026.PMID 42417054
- [3]Monnery D, Collins J, Droney J Practical prescribing in cancer cachexia Curr Opin Support Palliat Care, 2026.PMID 42411339
- [4]Shen S, Zhou K, Wu M, Liu D, et al. Feeding intelligence: comparative evaluation of ChatGPT and clinical guidelines for nutritional management in head and neck cancer J Transl Med, 2025.PMID 41272713
- [5]Muscaritoli M, Molfino A, Orlando S, Tambaro F Advancements of investigational agents for cancer cachexia: what clinical progress have we seen in the last 5 years? Expert Opin Investig Drugs, 2025.PMID 41222020
- [6]Hustad KS, Kaasa S, Laird BJA Integrated nutritional care in cancer; about time? Curr Opin Support Palliat Care, 2025.PMID 40689650
- [7]Xi Y, Yao T, Zhang C, Zhuang T Effectiveness of safety care and clinical nursing pathway in patients undergoing cardiovascular intervention: a randomized controlled trial Perioper Med (Lond), 2026.PMID 42469924
- [8]Marks FJ, Walters SJ, Sutton L, Jacques RM What statistical methods are more appropriate for predicting recruitment at the design stage of a randomised controlled trial? Trials, 2026.PMID 42469922