Phys Clinical Cases · gastrointestinal
Liver Transplantation — DCE Clinical Case
DCE long-case and short-case station for Liver Transplantation.
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Liver Transplantation — Clinical Case
DCE Long Case
Patient brief
Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Liver Transplantation. [1]
Presenting complaint: Subacute or acute symptoms referable to Liver Transplantation, with enough detail to force prioritisation. [1] [2]
Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]
Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]
Examination: Key positives and critical negatives for dangerous differentials. [1]
Investigations: A small set of results that change management. [1] [2]
Tasks
- Present a prioritised problem list. [1]
- Defend investigations and immediate therapy. [1] [2]
- Provide safety-net and follow-up advice. [2]
Model discussion points
- Working diagnosis and acuity. [1]
- Differentials and discriminators. [2]
- Treatment sequence and monitoring. [1] [2] [3]
- Multimorbidity and communication. [2]
Short case
Focused examination or counselling station linked to Liver Transplantation, with one interpretation task and one shared-decision point. [1] [2]
References
- [1]Ma Z, Niu Z, Yu A, Guo Y, et al. Severe hepatotoxicity associated with orlistat: clinical presentation, risk factors and outcomes Front Pharmacol, 2026.PMID 42465996
- [2]Tapia-Villacis S, Prieto J, López M, Medina J Disseminated Phaeohyphomycosis Due to Alternaria alternata in a Liver Transplant Recipient: Successful Treatment With Isavuconazole, a Case Report and Literature Review Case Rep Transplant, 2026.PMID 42465679
- [3]Lee H, Jung KU, Luu M, Kosari K, et al. Perioperative mortality and survival after lymph node excision in hepatocellular carcinoma: a national cancer database propensity score-matched cohort study World J Surg Oncol, 2026.PMID 42464368
- [4]Morales Junior R, Telles JP, Chua NGS, Kunicki PK, et al. Mapping Therapeutic Drug Monitoring Research in Low- and Middle-Income Countries: A Scoping Review (2015-2024) Ther Drug Monit, 2026.PMID 42457203
- [5]You H, Maiwall R, Chen J, Ahn SH, et al. APASL clinical practice guidelines on the management of chronic hepatitis B infection: a 2026 update Hepatol Int, 2026.PMID 42365189
- [6]Perito ER, Chen JK, Danziger-Isakov LA, Desai MS, et al. AASLD AST NASPGHAN Practice Guideline on pediatric liver transplantation: Post-transplant management Liver Transpl, 2026.PMID 42329162
- [7]Doan HN, Chang MC Comparative Effectiveness of Unstable Versus Stable Resistance Training on Lower Limb Strength, Mobility, and Fear of Falling in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials Am J Phys Med Rehabil, 2026.PMID 42468010
- [8]Liu HW, Tsai TL Virtual Reality-assisted Physiotherapeutic Training for Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis Am J Phys Med Rehabil, 2026.PMID 42468005