Phys Clinical Cases · oncological
Prostate Cancer — DCE Clinical Case
DCE long-case and short-case station for Prostate Cancer.
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Prostate Cancer — Clinical Case
DCE Long Case
Patient brief
Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Prostate Cancer. [1]
Presenting complaint: Subacute or acute symptoms referable to Prostate Cancer, with enough detail to force prioritisation. [1] [2]
Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]
Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]
Examination: Key positives and critical negatives for dangerous differentials. [1]
Investigations: A small set of results that change management. [1] [2]
Tasks
- Present a prioritised problem list. [1]
- Defend investigations and immediate therapy. [1] [2]
- Provide safety-net and follow-up advice. [2]
Model discussion points
- Working diagnosis and acuity. [1]
- Differentials and discriminators. [2]
- Treatment sequence and monitoring. [1] [2] [3]
- Multimorbidity and communication. [2]
Short case
Focused examination or counselling station linked to Prostate Cancer, with one interpretation task and one shared-decision point. [1] [2]
References
- [1]Tatarano S, Mitsuke A, Osako Y, Sakaguchi T, et al. NTRK fusion in metastatic castration-resistant prostate cancer treated with entrectinib: a case report J Med Case Rep, 2026.PMID 42469872
- [2]Akinnola OO, Olaniyan AI, Adeboye BA, Akinyosoye AD Impact of immunotherapy as a monotherapy or in combination with conventional therapies on regulatory T-cell (Treg) modulation in prostate cancer: a systematic review BMC Cancer, 2026.PMID 42469702
- [3]Watfa M, Dortche K, Fervaha G, Younis SK, et al. Long-term oncologic outcomes of patients with grade group 1 prostate cancer and pT3a disease on final pathology Prostate Cancer Prostatic Dis, 2026.PMID 42469509
- [4]Melchior F, Koett M, Aigner G, Schroffenegger J, et al. Real-World Use of Prolaris® to Guide Treatment Decisions in Localized Prostate Cancer Eligible for Active Surveillance Urol Int, 2026.PMID 42467602
- [5]Aly M, Joseph A, Amer T The Evidence-Practice Gap in Testosterone Therapy for Prostate Cancer: A Narrative Review Cureus, 2026.PMID 42465160
- [6]Buali HF, Al Shaibani A, Farouqi US, Abushloa T, et al. Prostate Cancer Screening: Current Controversies and Future Directions Cureus, 2026.PMID 42465149
- [7]Xi Y, Yao T, Zhang C, Zhuang T Effectiveness of safety care and clinical nursing pathway in patients undergoing cardiovascular intervention: a randomized controlled trial Perioper Med (Lond), 2026.PMID 42469924
- [8]Marks FJ, Walters SJ, Sutton L, Jacques RM What statistical methods are more appropriate for predicting recruitment at the design stage of a randomised controlled trial? Trials, 2026.PMID 42469922