Phys Clinical Cases · pharmacological
Salicylate Toxicity — DCE Clinical Case
DCE long-case and short-case station for Salicylate Toxicity.
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Salicylate Toxicity — Clinical Case
DCE Long Case
Patient brief
Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Salicylate Toxicity. [1]
Presenting complaint: Subacute or acute symptoms referable to Salicylate Toxicity, with enough detail to force prioritisation. [1] [2]
Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]
Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]
Examination: Key positives and critical negatives for dangerous differentials. [1]
Investigations: A small set of results that change management. [1] [2]
Tasks
- Present a prioritised problem list. [1]
- Defend investigations and immediate therapy. [1] [2]
- Provide safety-net and follow-up advice. [2]
Model discussion points
- Working diagnosis and acuity. [1]
- Differentials and discriminators. [2]
- Treatment sequence and monitoring. [1] [2] [3]
- Multimorbidity and communication. [2]
Short case
Focused examination or counselling station linked to Salicylate Toxicity, with one interpretation task and one shared-decision point. [1] [2]
References
- [1]Megaladevi P, Vadassery J Evolutionary trade-offs in plant immunity: prioritizing antiviral priming by herbivore-induced plant volatiles over defense against herbivores J Biosci, 2026.PMID 42345213
- [2]Palmer BF, Clegg DJ Pathophysiology of Ketoacidosis: Core Curriculum 2026 Am J Kidney Dis, 2026.PMID 42340294
- [3]Rather BA, Mir IR, Mahajan M, Qiao F, et al. Jasmonic acid crosstalk with secondary metabolites and plant growth regulators to maintain redox balance during crop improvement under salt stress Plant Sci, 2026.PMID 42314837
- [4]Hoegberg LCG, Gosselin S, Buckley NA, Wood DM, et al. Recommendations from the Clinical Toxicology Recommendations Collaborative on the administration of activated charcoal in acute oral overdose Clin Toxicol (Phila), 2026.PMID 41906697
- [5]Villanueva E, Carretero M, Aguirre MA, Negro A, et al. [Specific pharmacological treatment guide for transthyretin amyloid cardiomyopathy, 2021] Medicina (B Aires), 2022.PMID 35417392
- [6]Naito C, Yamaguchi T, Katsumi H, Kimura S, et al. Human Induced Pluripotent Stem Cell-Based Skin for Assessing Transdermal Drug Permeability and Irritancy Biol Pharm Bull, 2021.PMID 33390542
- [7]Doan HN, Chang MC Comparative Effectiveness of Unstable Versus Stable Resistance Training on Lower Limb Strength, Mobility, and Fear of Falling in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials Am J Phys Med Rehabil, 2026.PMID 42468010
- [8]Liu HW, Tsai TL Virtual Reality-assisted Physiotherapeutic Training for Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis Am J Phys Med Rehabil, 2026.PMID 42468005