Phys Clinical Cases · endocrine
Transgender Medicine AND Hormone Therapy — DCE Clinical Case
DCE long-case and short-case station for Transgender Medicine AND Hormone Therapy.
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Transgender Medicine AND Hormone Therapy — Clinical Case
DCE Long Case
Patient brief
Patient: A middle-aged or older adult with multimorbidity and a presentation centred on Transgender Medicine AND Hormone Therapy. [1]
Presenting complaint: Subacute or acute symptoms referable to Transgender Medicine AND Hormone Therapy, with enough detail to force prioritisation. [1] [2]
Past history: Common cardiometabolic and organ comorbidities that interact with the plan. [2]
Medications: A polypharmacy list that includes at least one interaction or dosing issue. [2]
Examination: Key positives and critical negatives for dangerous differentials. [1]
Investigations: A small set of results that change management. [1] [2]
Tasks
- Present a prioritised problem list. [1]
- Defend investigations and immediate therapy. [1] [2]
- Provide safety-net and follow-up advice. [2]
Model discussion points
- Working diagnosis and acuity. [1]
- Differentials and discriminators. [2]
- Treatment sequence and monitoring. [1] [2] [3]
- Multimorbidity and communication. [2]
Short case
Focused examination or counselling station linked to Transgender Medicine AND Hormone Therapy, with one interpretation task and one shared-decision point. [1] [2]
References
- [1]Hastie E, Khetan P, LaMere SA, George AF, et al. The HIV Reservoir and Immune Landscape Across the Life Course of Women: Implications for Cure Strategies Am J Reprod Immunol, 2026.PMID 42461585
- [2]Yoon JW, Kim G, Lee ES, Lee SY, et al. Cervical cancer screening and HPV vaccination among assigned female at birth transgender and gender-diverse individuals in South Korea: findings from the KITE cohort BMC Public Health, 2026.PMID 42437894
- [3]Thomas TA, Winston-McPherson GN, Amarillo I, Berry AD, et al. ADLM Guidance Document on Incorporating Gender Diversity in Pathology and Laboratory Medicine J Appl Lab Med, 2026.PMID 42383916
- [4]Hastie E, Bortner A, Wagner GA, Blumenthal J Gender-Affirming Medical Treatment of Transgender and Gender-Diverse Individuals Obstet Gynecol Clin North Am, 2026.PMID 42236065
- [5]Xi Y, Yao T, Zhang C, Zhuang T Effectiveness of safety care and clinical nursing pathway in patients undergoing cardiovascular intervention: a randomized controlled trial Perioper Med (Lond), 2026.PMID 42469924
- [6]Marks FJ, Walters SJ, Sutton L, Jacques RM What statistical methods are more appropriate for predicting recruitment at the design stage of a randomised controlled trial? Trials, 2026.PMID 42469922
- [7]Hajiaqaei M, Mohammadi A Transcranial random noise stimulation (tRNS) over the left dorsolateral prefrontal cortex ameliorates emotion dysregulation and executive function: a single-blind, randomized, sham-controlled clinical trial BMC Psychol, 2026.PMID 42469906
- [8]Weiß A, Haussmann J, Goeckenjan M Establishing a Transgender Outpatient Clinic Within the Gynaecology Department: a Retrospective Analysis of the First Few Years Geburtshilfe Frauenheilkd, 2026.PMID 42459842