Phys Vivas · dermatological
Drug Eruptions AND Severe Cutaneous Adverse Reactions — Viva Defence
DCE viva defence for Drug Eruptions AND Severe Cutaneous Adverse Reactions.
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Target exams
Drug Eruptions AND Severe Cutaneous Adverse Reactions Viva
Long Case Viva Defence
Opening statement
"This patient presents with a problem best framed as Drug Eruptions AND Severe Cutaneous Adverse Reactions. My priorities are to identify red flags, confirm the mechanism with purposeful investigations, start a sequenced management plan, and integrate multimorbidity and follow-up." [1] [2]
Examiner questions
Q1: "What makes this urgent?" [1]
"I look for threats to airway, perfusion, neurology, metabolism, infection or bleeding, and I escalate those before elective work-up." [1] [2]
Q2: "What is your first investigation package?" [2]
"I order tests that change management now, not a scattergun panel." [1] [2]
Q3: "Walk me through treatment." [1]
"Stabilise, treat the mechanism, prevent complications, and plan monitoring." [1] [2] [3]
Q4: "What is the classic trap?" [2]
"Treating a label without confirming the discriminating mechanism, or delaying escalation." [1] [2]
Short case
Counsel the patient on the plan, risks and warning symptoms in plain language. [1] [2]
References
- [1]Takada T Antithrombotic Drug Eruptions in Dermatology Practice: Selection Bias, Clinical Phenotypes, and Diagnostic Approaches Cureus, 2026.PMID 42465709
- [2]Srisuwatchari W, Norchai P Hypersensitivity reactions associated with nutraceuticals and dietary supplements: A narrative review Asian Pac J Allergy Immunol, 2026.PMID 42437383
- [3]Mullan KA, Davies S, Teoh K, Tucker HL, et al. Immunological and molecular signatures of carbamazepine-induced maculopapular exanthema Front Immunol, 2026.PMID 42433382
- [4]Omran S, Gan SH, Teoh SL Pharmacogenomics in drug therapy: global regulatory guidelines for managing high-risk drug reactions Eur J Hum Genet, 2026.PMID 40993225
- [5]Wu PC, Chen WT, Huang IH, Chen CB, et al. Human Leukocyte Antigens and Sulfamethoxazole/Cotrimoxazole-Induced Severe Cutaneous Adverse Reactions: A Systematic Review and Meta-Analysis JAMA Dermatol, 2024.PMID 38568509
- [6]Asgarpour JMS, Lam LM, Vogel TK, Goez HR, et al. Human Leukocyte Antigen Gene Testing and Carbamazepine-Induced Toxic Epidermal Necrolysis: A Study of Pediatric Practice J Cutan Med Surg, 2021.PMID 32909461
- [7]Doan HN, Chang MC Comparative Effectiveness of Unstable Versus Stable Resistance Training on Lower Limb Strength, Mobility, and Fear of Falling in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials Am J Phys Med Rehabil, 2026.PMID 42468010
- [8]Liu HW, Tsai TL Virtual Reality-assisted Physiotherapeutic Training for Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis Am J Phys Med Rehabil, 2026.PMID 42468005