Phys Vivas · pharmacological
Therapeutic Drug Monitoring — Viva Defence
DCE viva defence for Therapeutic Drug Monitoring.
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Target exams
Therapeutic Drug Monitoring Viva
Long Case Viva Defence
Opening statement
"This patient presents with a problem best framed as Therapeutic Drug Monitoring. My priorities are to identify red flags, confirm the mechanism with purposeful investigations, start a sequenced management plan, and integrate multimorbidity and follow-up." [1] [2]
Examiner questions
Q1: "What makes this urgent?" [1]
"I look for threats to airway, perfusion, neurology, metabolism, infection or bleeding, and I escalate those before elective work-up." [1] [2]
Q2: "What is your first investigation package?" [2]
"I order tests that change management now, not a scattergun panel." [1] [2]
Q3: "Walk me through treatment." [1]
"Stabilise, treat the mechanism, prevent complications, and plan monitoring." [1] [2] [3]
Q4: "What is the classic trap?" [2]
"Treating a label without confirming the discriminating mechanism, or delaying escalation." [1] [2]
Short case
Counsel the patient on the plan, risks and warning symptoms in plain language. [1] [2]
References
- [1]DiStefano MJ, Tilley A, Paratane D, Gyimah Gyamfi H, et al. Postshortage Compounded GLP-1 RA Market in 2 States With Potentially High Demand JAMA Health Forum, 2026.PMID 42467450
- [2]Ullah A Baxdrostat and selective aldosterone synthase inhibition in hard-to-control hypertension: mechanism, evidence, safety, and future clinical positioning Expert Opin Pharmacother, 2026.PMID 42467440
- [3]Kim JE, Noh JY, Lee KE, Lee YI, et al. Non-Cytopathic Mammalian Orthoreovirus Infection Triggers Innate Immune Responses in Human Tonsil-Derived Mesenchymal Stem Cells: Implications for Cell Therapy Quality Control Tissue Eng Regen Med, 2026.PMID 42467368
- [4]Deressa JD, Behaksra SW, Molla E, Letebo A, et al. Therapeutic efficacy of artemether-lumefantrine plus single low dose primaquine for the treatment of uncomplicated Plasmodium falciparum malaria in a high transmission setting, Western Ethiopia PLoS One, 2026.PMID 42467750
- [5]Morales Junior R, Telles JP, Chua NGS, Kunicki PK, et al. Mapping Therapeutic Drug Monitoring Research in Low- and Middle-Income Countries: A Scoping Review (2015-2024) Ther Drug Monit, 2026.PMID 42457203
- [6]McGarity MZ, Pollack CC, Currier EA, Godoshian AC, et al. Characteristics Influencing Adherence to SARS-CoV-2 Serial Antigen Testing Following a Federal Safety Communication: Cohort Study JMIR Public Health Surveill, 2026.PMID 42456150
- [7]Doan HN, Chang MC Comparative Effectiveness of Unstable Versus Stable Resistance Training on Lower Limb Strength, Mobility, and Fear of Falling in Older Adults: A Systematic Review and Meta-analysis of Randomized Controlled Trials Am J Phys Med Rehabil, 2026.PMID 42468010
- [8]Liu HW, Tsai TL Virtual Reality-assisted Physiotherapeutic Training for Patients With Knee Osteoarthritis: A Systematic Review and Meta-analysis Am J Phys Med Rehabil, 2026.PMID 42468005