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Clinical Atlas Prestige · Evidence-first

Psych CASC / OSCEAddiction psychiatry — hallucinogen-related disorders

Psych CASC / OSCE · Addiction psychiatry — hallucinogen-related disorders

Explain bad trip care, HPPD risk, and why trial psilocybin is not a microdosing script — CASC communication station

MRCPsych/FRANZCP-style communication station: explain intoxication versus primary psychosis, supportive acute care, HPPD risk in plain language, and honest PAT trial framing without colluding with unsupervised use.

communication
On this page & tools

Target exams

FRANZCPMRCPsychABPNMD-DNB

Target exams

FRANZCPMRCPsychABPNMD-DNB
Prompt
A 23-year-old is clearing after a mushroom bad trip managed with talk-down. His mother fears he has schizophrenia and wants lifelong depot. He wants a 'microdosing prescription like in the depression studies.' He has mild residual anxiety, no ongoing psychosis, and asks whether he can drive home tonight.

Station brief

Format. Communication station, approximately 7–10 minutes active time after reading. You are the psychiatry/addiction registrar. Examiner may play patient and/or mother. [1]

Candidate instructions. Explain what happened during the bad trip in plain language. Address schizophrenia fears without day-one lifelong labelling. Describe rare but real HPPD risk. Explain why research psilocybin doses with psychological support are not the same as unsupervised microdosing. Advise on driving, follow-up and safer-use/harm reduction without moralising. Check understanding and agree a plan. [1][4]

Candidate scenario

He is medically stable after psilocybin mushroom intoxication with panic that settled with talk-down. No ongoing delusions. Mother demands depot "so this never happens." He wants microdosing "like the NEJM depression study." He hopes to drive home tonight. You propose observation until fully clear, no driving, brief AOD follow-up, and evidence-based discussion of depression care if low mood is an issue. [4][5]

Marking domains

  • Empathy, structure, non-stigmatising language
  • Accurate plain-language model of intoxication vs primary psychosis
  • Honest explanation of HPPD as uncommon but real
  • Clear statement that trial psilocybin with support ≠ home microdosing script
  • Safety: residual effects, no driving, when to return
  • Negotiates mother's depot demand without collusion
  • Checks understanding / teach-back [1][3][4]
Reveal assessor key

Open. Name time; ask patient and mother top concerns (going mad, addiction medicines, wanting a "treatment dose"). [1]

Explain the bad trip. "Mushrooms contain psilocybin, which strongly affects brain serotonin 5-HT2A systems that help organise perception and sense of self. For some hours that can cause intense visual changes and panic — a bad trip. We keep people safe in a calm environment and support them until it settles; most people do not need long-term antipsychotic from a single episode." [2][1]

Mother's schizophrenia fear. Acknowledge fear; explain temporal link to the drug and settling with abstinence; dual formulation if symptoms returned and persisted; lifelong depot not automatic after one intoxication. [5]

HPPD. "A small number of people get ongoing visual disturbances after the drug has worn off — trailing lights, patterns — that interfere with life. It is uncommon but real. Stopping further psychedelics and getting follow-up helps; tell us if that appears." [3]

Microdosing request. "Some carefully run trials give a measured high dose such as 25 milligrams of pure psilocybin with preparation and therapists present, and they have shown benefits for some people with hard-to-treat depression. That is not the same as buying unknown doses or microdosing at home, and it is not a standard prescription I can write today for recreational products. If depression is the issue, we can discuss proven treatments and, where available, legitimate research pathways — not DIY." [4][1]

Driving and plan. No driving until fully clear; crisis contacts; AOD brief intervention; follow-up if mood, psychosis or visual symptoms; harm reduction (set/setting, adulterants, not using alone, avoiding if psychosis risk). Teach-back. [1][5]

Close. Summarise; check understanding; written advice. [1]

References

  1. [1]Johnson MW, Richards WA, Griffiths RR Human hallucinogen research: guidelines for safety J Psychopharmacol, 2008.PMID 18593734
  2. [2]Nichols DE Psychedelics Pharmacol Rev, 2016.PMID 26841800
  3. [3]Halpern JH, Pope HG Jr Hallucinogen persisting perception disorder: what do we know after 50 years? Drug Alcohol Depend, 2003.PMID 12609692
  4. [4]Goodwin GM, Aaronson ST, Alvarez O, et al. Single-Dose Psilocybin for a Treatment-Resistant Episode of Major Depression N Engl J Med, 2022.PMID 36322843
  5. [5]Carbonaro TM, Bradstreet MP, Barrett FS, et al. Survey study of challenging experiences after ingesting psilocybin mushrooms J Psychopharmacol, 2016.PMID 27578767