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Clinical Atlas Prestige · Evidence-first

Psych MEQs / SAQsOld age psychiatry — falls polypharmacy frailty

Psych MEQs / SAQs · Old age psychiatry — falls polypharmacy frailty

Falls, polypharmacy and frailty in old-age psychiatry (MEQ)

FRANZCP-style MEQ on falls, polypharmacy and frailty at the old-age psychiatry interface: Fried/Rockwood, FRIDs, multifactorial prevention, deprescribing, antipsychotic mortality literacy.

20 marks20 min
On this page & tools

Target exams

FRANZCPMRCPsychABPNMD-DNB

Target exams

FRANZCPMRCPsychABPNMD-DNB
Prompt
An 83-year-old woman living in residential care has moderate Alzheimer disease, hypertension on a thiazide, two falls in the past month (one with facial bruising), and staff report evening 'agitation' during personal care. Medications include risperidone 0.5 mg twice daily (started 10 months ago for 'behaviour,' no review date), temazepam 10–20 mg most nights, oxybutynin, and recently started sertraline 50 mg. Daughter asks whether to 'give something stronger to settle her' and whether falls mean all psychotropics must stop forever. (i) Define frailty frameworks relevant to her risk and why falls, polypharmacy and frailty are one clinical problem. (ii) Critically review her regimen using Beers/STOPP and FRID concepts. (iii) Outline a multifactorial falls assessment and evidence-based prevention plan. (iv) Discuss deprescribing versus continued psychotropic treatment, including antipsychotic black-box framing and an illustrative safer antidepressant monitoring plan. (v) Address family communication and disposition. (20 marks)

Model answer

Reveal model answer (i–v)

(i) Frailty and the integrated problem. Frailty is increased vulnerability to poor recovery after stressors (Clegg). Fried phenotype uses five criteria (weight loss, exhaustion, low activity, slow gait, weak grip; ≥3 frail). Rockwood frames cumulative deficits / Clinical Frailty Scale. In this resident, dementia, multimorbidity, polypharmacy and recurrent falls mark high vulnerability: the same psychotropic load that might be tolerated mid-life drives sedation, orthostasis and injury. Falls, polypharmacy and frailty are one system — not separate checklists.[1][2]

(ii) Beers / STOPP / FRID review. Temazepam is a classic Beers PIM and FRID (sedative-hypnotic fall risk). Long-term risperidone without review for non-specific "behaviour" fails dementia antipsychotic principles and adds FRID + mortality/stroke concerns. Oxybutynin adds anticholinergic burden (cognition, falls). Sertraline may be appropriate if depression is real, but thiazide + age raise hyponatraemia risk that can present as falls/confusion — check sodium. STOPP thinking stops unnecessary CNS sedatives; START thinking still asks whether pain, constipation, depression or sensory needs are under-treated.[3][4][5][6][10]

(iii) Multifactorial falls plan. Structured falls history (timing vs doses, prodrome, injury), orthostatic BP, gait/balance, vision, footwear, environment, cognition/delirium screen, bone health. Interventions: exercise/physio where feasible, environmental modification, treat orthostasis, medication review as core (not physio-only), staff ABC strategies for personal-care distress. Gillespie supports exercise and home safety in community; AGS/BGS supports multifactorial assessment — adapt intensity to RACF context.[7][8]

(iv) Deprescribe vs treat. Deprescribing is planned supervised taper/stop of harmful or non-beneficial drugs (Scott), not chaos and not permanent ban on all psychotropics. Plan gradual temazepam reduction with sleep supports; supervised risperidone taper with restart threshold only if severe aggression/risk returns, documenting target and time-limit — Schneider mortality meta-analysis underpins black-box literacy. For depression, continue or adjust sertraline carefully (e.g. ensure therapeutic trial, early Na check with thiazide) rather than under-treating severe mood illness solely for falls fear. One change at a time when frail when possible.[9][10][4]

(v) Family and disposition. Empathic dual-agenda talk: reduce drug harm and falls without abandoning comfort/safety. Plain language on antipsychotic risks in dementia; written facility plan; pharmacy and GP shared care; early review if behaviour escalates; teach-back. Disposition may include old-age CMHT input, falls/physio pathways, RACF medication advisory processes.[9][10]

References

  1. [1]Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype J Gerontol A Biol Sci Med Sci, 2001.PMID 11253156
  2. [2]Clegg A, Young J, Iliffe S, et al. Frailty in elderly people Lancet, 2013.PMID 23395245
  3. [3]Woolcott JC, Richardson KJ, Wiens MO, et al. Meta-analysis of the impact of 9 medication classes on falls in elderly persons Arch Intern Med, 2009.PMID 19933955
  4. [4]Seppala LJ, Wermelink AMAT, de Vries M, et al. Fall-Risk-Increasing Drugs: A Systematic Review and Meta-Analysis: II. Psychotropics J Am Med Dir Assoc, 2018.PMID 29402652
  5. [5]By the 2023 American Geriatrics Society Beers Criteria Update Expert Panel American Geriatrics Society 2023 updated AGS Beers Criteria for potentially inappropriate medication use in older adults J Am Geriatr Soc, 2023.PMID 37139824
  6. [6]O'Mahony D, O'Sullivan D, Byrne S, et al. STOPP/START criteria for potentially inappropriate prescribing in older people: version 2 Age Ageing, 2015.PMID 25324330
  7. [7]Panel on Prevention of Falls in Older Persons, AGS/BGS Summary of the Updated American Geriatrics Society/British Geriatrics Society clinical practice guideline for prevention of falls in older persons J Am Geriatr Soc, 2011.PMID 21226685
  8. [8]Gillespie LD, Robertson MC, Gillespie WJ, et al. Interventions for preventing falls in older people living in the community Cochrane Database Syst Rev, 2012.PMID 22972103
  9. [9]Scott IA, Hilmer SN, Reeve E, et al. Reducing inappropriate polypharmacy: the process of deprescribing JAMA Intern Med, 2015.PMID 25798731
  10. [10]Schneider LS, Dagerman KS, Insel P Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials JAMA, 2005.PMID 16234500