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Clinical Atlas Prestige · Evidence-first

Psych VivasPsychopharmacology — ECT and neurostimulation

Psych Vivas · Psychopharmacology — ECT and neurostimulation

ECT and neurostimulation — consultant viva

Fellowship viva covering ECT efficacy evidence, placement/dosing, anaesthesia literacy, cognitive risks, continuation, TRS augmentation, and evidence-tiered rTMS/VNS/DBS.

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On this page & tools

Target exams

FRANZCPMRCPsychABPNMD-DNB

Target exams

FRANZCPMRCPsychABPNMD-DNB
Prompt
Examiner places cards: UK ECT Review Group, CORE continuation, RUL vs BT, ultrabrief, cuff technique, catatonia, Petrides clozapine-ECT, THREE-D iTBS, BROADEN DBS, RANZCP ECT PPG.

Station structure

Time: 8–10 minutes. Depth: consultant teaching registrar. Expect named trials, placement physics without equations, legal humility (no invented sections), and clear device tiers.[1][7][8]

Core questions and model points

  1. What is ECT and why does it work clinically? Brief-pulse electrical induction of a generalised cerebral seizure under anaesthesia/muscle relaxation. Motor convulsion is a monitoring proxy (cuff technique). Mechanisms multi-pathway (neuroplastic, monoamine, anticonvulsant adaptation). Efficacy strongest for severe depression; also catatonia, mania, selected psychosis pathways.[8]

  2. Evidence elevator pitch? UK ECT Review Group: real greater than sham; bilateral moderately greater than unilateral; often greater than drugs short-term. CORE: rapid response; continuation strategies matter because relapse is common without a plan.[1][2]

  3. RUL vs BT — how do you choose? Cognition priority and less urgency → RUL/ultrabrief at high suprathreshold dose. Severity, urgency, RUL non-response → BT. Sackeim: placement and pulse width drive efficacy–cognition trade-off.[3][8]

  4. Cognitive adverse effects — how do you counsel? Post-ictal confusion; temporary anterograde impairment; variable retrograde autobiographical risk (most feared). Mitigate with placement/pulse width; never gaslight; balance against untreated illness risk.[3][10]

  5. Catatonia card. Examine with BFCRS structure; lorazepam trial; urgent ECT if malignant features or benzo failure. Do not delay for weeks of SSRI trials.[9][8]

  6. Clozapine-resistant schizophrenia. After optimised clozapine, ECT augmentation has randomised evidence (Petrides) — name it.[4]

  7. rTMS/iTBS card. Outpatient TRD option; sham-controlled trials; THREE-D iTBS non-inferior to 10 Hz with shorter sessions. Not a substitute for emergency ECT.[5]

  8. DBS card. Early open-label SCC hope; BROADEN failed primary endpoint — not routine care.[6]

  9. Governance. RANZCP ECT PPG (Weiss): consent, training, facilities, monitoring standards for ANZ. Capacity decision-specific; involuntary only under local law.[7]

Examiner probes (corners)

  • "Why might seizure threshold rise during a course?" Anticonvulsant adaptation; dose may need increase; review benzos/anticonvulsants.[8]
  • "She remitted after eight ECTs — are you done?" No — continuation pharmacotherapy and/or C-ECT plan.[2]
  • "Family wants 'natural therapy only'." Acknowledge values; state mortality risk of untreated severe depression/catatonia; offer second opinion; legal pathway if capacity absent and risk extreme.[7][8]

Pass behaviours

Names trials accurately; places devices on evidence tiers; discusses memory without minimising; plans continuation; respects jurisdiction-specific law without fabricating statutes.[1][2][6][7]

References

  1. [1]UK ECT Review Group Efficacy and safety of electroconvulsive therapy in depressive disorders: a systematic review and meta-analysis Lancet, 2003.PMID 12642045
  2. [2]Kellner CH, Knapp RG, Petrides G, et al. Continuation electroconvulsive therapy vs pharmacotherapy for relapse prevention in major depression: CORE Arch Gen Psychiatry, 2006.PMID 17146008
  3. [3]Sackeim HA, Prudic J, Nobler MS, et al. Effects of pulse width and electrode placement on the efficacy and cognitive effects of electroconvulsive therapy Brain Stimul, 2008.PMID 19756236
  4. [4]Petrides G, Malur C, Braga RJ, et al. Electroconvulsive therapy augmentation in clozapine-resistant schizophrenia: a prospective, randomized study Am J Psychiatry, 2015.PMID 25157964
  5. [5]Blumberger DM, Vila-Rodriguez F, Thorpe KE, et al. Effectiveness of theta burst versus high-frequency repetitive transcranial magnetic stimulation in patients with depression (THREE-D) Lancet, 2018.PMID 29726344
  6. [6]Holtzheimer PE, Husain MM, Lisanby SH, et al. Subcallosal cingulate deep brain stimulation for treatment-resistant depression: BROADEN Lancet Psychiatry, 2017.PMID 28988904
  7. [7]Weiss A, Hussain S, Ng B, et al. RANZCP professional practice guidelines for the administration of electroconvulsive therapy Aust N Z J Psychiatry, 2019.PMID 30966782
  8. [8]Espinoza RT, Kellner CH Electroconvulsive Therapy N Engl J Med, 2022.PMID 35172057
  9. [9]Bush G, Fink M, Petrides G, et al. Catatonia. I. Rating scale and standardized examination Acta Psychiatr Scand, 1996.PMID 8686483
  10. [10]Sackeim HA, Prudic J, Fuller R, et al. The cognitive effects of electroconvulsive therapy in community settings Neuropsychopharmacology, 2007.PMID 16936712