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Clinical Atlas Prestige · Evidence-first

Psych VivasGeneral adult psychiatry — early psychosis pathway

Psych Vivas · General adult psychiatry — early psychosis pathway

First-episode psychosis — structured clinical viva

Fellowship viva on FEP pathway: DUP, organic work-up, OPUS/RAISE, low-dose starts, maintenance after remission, cannabis, IPS, and communication with family.

clinical
On this page & tools

Target exams

FRANZCPMRCPsychABPNMD-DNB

Target exams

FRANZCPMRCPsychABPNMD-DNB
Prompt
You are the psychiatry registrar in the early intervention clinic. A 21-year-old man presents with a first episode of psychosis after 4 months of untreated persecutory delusions and auditory commentary. His mother asks: (1) Is this schizophrenia forever? (2) Why not the strongest tablet now? (3) How long must he stay on medication if he gets better? (4) Should he quit university? Discuss assessment priorities, organic exclusion, EIS evidence, dosing, maintenance duration, family work and vocational recovery.

Interpretation

Reveal interpretation

Assessment spine. Risk (suicide, violence, vulnerability), MSE with examples, collateral, substance timeline, DUP about 4 months of frank psychosis (already prognostic), capacity/legal status under local statute, and medical exclusion. Observations and glucose if not done; baseline metabolic panel and ECG before antipsychotic.[2]

"Is this schizophrenia forever?" Answer with pathway language: this is first-episode psychosis; the operational label may evolve with duration; many people improve substantially with early multi-element care; avoid fatalism while remaining honest that some need longer treatment.[1]

"Strongest tablet now?" FEP responds to lower doses; high-dose polypharmacy increases harm. Name a first-line plan (e.g. aripiprazole 10 mg daily) with monitoring. Clozapine is for treatment resistance after adequate trials, not automatic first dose.[1]

Maintenance duration. After remission, early stop carries high recurrence risk; counsel continued treatment typically for at least 1–2 years with shared decision-making; any taper is supervised with early-warning plans.[3]

University. Temporary adjustment may help; automatic abandonment is wrong. Offer IPS / supported education integrated with the team — vocational recovery is evidence-based, not a luxury after "full cure."[4]

Evidence names for the examiner. Marshall/Perkins on DUP; OPUS; RAISE-ETP; Correll EIS meta-analysis; Zipursky discontinuation risk; Killackey IPS; family intervention evidence.[1][2][4]

Key points

FEP is a pathway label

Treat now; refine diagnosis over time; do not deliver lifelong fatalism on day one.

Shorten DUP and use multi-element care

Medication plus family, case management, substance work and vocational support beats fragmented care.

Maintenance is not optional trivia

High relapse after early stop; plan duration and deprescribing explicitly.
[1] [3]

References

  1. [1]Kane JM, Robinson DG, Schooler NR, et al. Comprehensive Versus Usual Community Care for First-Episode Psychosis: 2-Year Outcomes From the NIMH RAISE Early Treatment Program Am J Psychiatry, 2016.PMID 26481174
  2. [2]Marshall M, Lewis S, Lockwood A, et al. Association between duration of untreated psychosis and outcome in cohorts of first-episode patients: a systematic review Arch Gen Psychiatry, 2005.PMID 16143729
  3. [3]Zipursky RB, Menezes NM, Streiner DL Risk of symptom recurrence with medication discontinuation in first-episode psychosis: a systematic review Schizophr Res, 2014.PMID 23972821
  4. [4]Killackey E, Allott K, Jackson HJ, et al. Individual placement and support for vocational recovery in first-episode psychosis: randomised controlled trial Br J Psychiatry, 2019.PMID 30251616