Bell's Palsy
Summary
Bell's palsy is an acute, idiopathic, unilateral lower motor neuron (LMN) facial nerve (CN VII) palsy. It is the most common cause of acute facial paralysis, affecting approximately 20-30 per 100,000 people annually. The presumed aetiology involves viral reactivation (particularly HSV-1) causing inflammation and swelling of the facial nerve within the temporal bone. The hallmark is sudden-onset unilateral facial weakness affecting the entire side of the face, including the forehead (distinguishing it from upper motor neuron lesions). Treatment with corticosteroids within 72 hours improves outcomes. Eye care is essential to prevent exposure keratopathy. Prognosis is generally excellent, with 70-85% of patients achieving complete recovery.
Key Facts
- Incidence: 20-30 per 100,000 per year
- Aetiology: Presumed viral (HSV-1) reactivation
- Key feature: LMN facial weakness — forehead affected
- Treatment: Prednisolone 50mg OD for 10 days (start within 72h)
- Eye care: Critical to prevent exposure keratitis
- Prognosis: 70-85% full recovery without treatment; improves with steroids
Clinical Pearls
Forehead Is Key: LMN (Bell's) = forehead and lower face affected (cannot wrinkle forehead). UMN (Stroke) = forehead spared (bilateral cortical innervation).
Bell's Phenomenon: When the patient attempts to close the eye, the eyeball rolls upward, exposing the sclera. This is a normal protective reflex, visible because eyelid closure is weak.
Start Steroids Early: Maximum benefit if prednisolone started within 72 hours of symptom onset. After 72 hours, benefit is less clear.
Why This Matters Clinically
Bell's palsy is the most common cause of acute facial weakness. Rapid recognition, early steroid treatment, and appropriate eye care prevent complications and optimise recovery. It is also critical to distinguish from stroke and other causes of facial weakness.
Incidence & Prevalence
- Incidence: 20-30 per 100,000 per year
- Lifetime risk: ~1 in 60
- Recurrence: 7-15% (same or opposite side)
Demographics
| Factor | Details |
|---|---|
| Age | Peak 15-45 years; can occur at any age |
| Sex | Equal |
| Pregnancy | 3x increased risk (especially third trimester and postpartum) |
| Diabetes | Increased risk and possibly worse outcomes |
Risk Factors
| Factor | Impact |
|---|---|
| Pregnancy | Increased risk |
| Diabetes mellitus | Increased risk, possibly more severe |
| Upper respiratory infection | Preceding infection in some |
| Family history | 4-14% have affected relatives |
| Immunosuppression | Increased risk |
Mechanism
Step 1: Viral Reactivation
- HSV-1 (most commonly implicated) latent in geniculate ganglion
- Reactivation triggered by stress, immunosuppression, cold exposure
Step 2: Nerve Inflammation
- Inflammation and oedema of facial nerve
- Compression within narrow bony fallopian canal (temporal bone)
Step 3: Demyelination and Axonal Injury
- Segmental demyelination (neurapraxia) → good recovery
- Axonal degeneration (axonotmesis) → slower, incomplete recovery
Step 4: Denervation of Facial Muscles
- Unilateral weakness of all muscles of facial expression
- Including frontalis (forehead), orbicularis oculi (eye closure), orbicularis oris (mouth)
Anatomy Reminder
| Segment | Location |
|---|---|
| Intracranial | Brainstem to internal acoustic meatus |
| Intratemporal | Through temporal bone (narrowest point = labyrinthine segment) |
| Extratemporal | Exits stylomastoid foramen; divides in parotid gland |
Branches of Facial Nerve (Temporal-Zygomatic-Buccal-Mandibular-Cervical)
- Motor: Muscles of facial expression
- Sensory: Taste (anterior 2/3 tongue via chorda tympani)
- Parasympathetic: Lacrimation (greater petrosal nerve), salivation (submandibular, sublingual)
Symptoms
Signs
| Feature | Details |
|---|---|
| Forehead | Cannot wrinkle; eyebrow droops |
| Eye | Incomplete closure; Bell's phenomenon |
| Nasolabial fold | Flattened |
| Mouth | Corner droops; difficulty blowing out cheeks |
| Ear | No vesicles (distinguishes from Ramsay Hunt) |
House-Brackmann Grading
| Grade | Description |
|---|---|
| I | Normal |
| II | Slight weakness; complete eye closure |
| III | Obvious but not disfiguring; incomplete eye closure |
| IV | Obvious disfiguring; incomplete eye closure |
| V | Barely perceptible motion |
| VI | Complete paralysis |
Red Flags
[!CAUTION] Red Flags — Consider alternative diagnosis if:
- Forehead spared (UMN lesion — stroke)
- Vesicles in ear (Ramsay Hunt syndrome — varicella zoster)
- Bilateral weakness (GBS, Lyme, sarcoidosis)
- Gradual onset or progressive over weeks (tumour)
- Other cranial nerve involvement
- No improvement by 4 months
Structured Approach
Observe at Rest:
- Facial asymmetry
- Nasolabial fold flattening
- Mouth droop
Active Movement:
- Raise eyebrows (frontalis — preserved in UMN)
- Close eyes tight (orbicularis oculi)
- Smile (zygomatic, buccal branches)
- Blow out cheeks
- Whistle or purse lips
Bell's Phenomenon:
- Ask patient to close eyes
- Observe incomplete closure; eye rolls up
Ear Examination:
- Look for vesicles (Ramsay Hunt if present)
Neurological Examination:
- Other cranial nerves (especially V, VIII, IX)
- Limb examination if stroke suspected
Special Tests
| Test | Technique | Purpose |
|---|---|---|
| Schirmer's test | Filter paper in lower lid | Tear production (lacrimation) |
| Taste testing | Sweet/sour on anterior tongue | Chorda tympani function |
| Stapedial reflex | Audiometry | Hyperacusis assessment |
Clinical Diagnosis
- Bell's palsy is a clinical diagnosis of exclusion
- Investigations only needed if red flags or atypical features
When to Investigate
| Indication | Test |
|---|---|
| Suspected stroke | CT/MRI brain |
| Ramsay Hunt features | VZV PCR, clinical |
| Lyme disease endemic area | Lyme serology |
| Sarcoidosis suspected | Chest X-ray, ACE level |
| Tumour suspected (gradual onset, no recovery) | MRI with gadolinium |
| Recurrent or bilateral | Full investigation as above |
Electrodiagnostic Tests (Rarely Needed)
| Test | Indication |
|---|---|
| Electroneurography (ENoG) | Severe paralysis; prognostic (if >0% degeneration, poor outcome) |
| EMG | Assess reinnervation in late/chronic cases |
Management Algorithm
ACUTE FACIAL PALSY
↓
┌────────────────────────────────────────┐
│ 1. Assess for Red Flags │
│ - Forehead sparing (stroke)? │
│ - Vesicles (Ramsay Hunt)? │
│ - Bilateral/gradual/other CN? │
└────────────────────────────────────────┘
↓
┌────────────────────────────────────────┐
│ 2. If Bell's Palsy Diagnosed │
├────────────────────────────────────────┤
│ START WITHIN 72 HOURS: │
│ - Prednisolone 50mg OD for 10 days │
│ (60mg OD in some guidelines) │
│ - Antivirals: NOT routinely │
│ recommended (add if Ramsay Hunt) │
└────────────────────────────────────────┘
↓
┌────────────────────────────────────────┐
│ 3. Eye Care (Essential) │
├────────────────────────────────────────┤
│ - Artificial tears (frequent) │
│ - Eye ointment at night │
│ - Tape eye closed at night │
│ - Consider eye patch or moisture │
│ chamber │
└────────────────────────────────────────┘
↓
┌────────────────────────────────────────┐
│ 4. Follow-Up │
│ - Review at 2-4 weeks │
│ - Refer if no improvement by 4mo │
└────────────────────────────────────────┘
Medical Treatment
| Medication | Dose | Evidence |
|---|---|---|
| Prednisolone | 50-60mg OD for 10 days | Strong evidence (NNT ~6) |
| Antivirals (Aciclovir) | 400mg 5x/day for 7 days | No added benefit in uncomplicated Bell's; use in Ramsay Hunt |
Key Points:
- Start steroids within 72 hours
- No need to taper
- Antivirals add no benefit for Bell's palsy alone (Cochrane 2015)
- Add antivirals if Ramsay Hunt (vesicles + facial palsy)
Eye Care
| Intervention | Purpose |
|---|---|
| Artificial tears | Prevent drying |
| Eye ointment (lubricating) | Night-time protection |
| Taping eye closed | At night; prevents exposure |
| Moisture chamber/glasses | Protect from wind |
| Urgent ophthalmology referral | If corneal ulceration suspected |
Referral
| Indication | Referral |
|---|---|
| Complete paralysis | ENT or neurology |
| No improvement by 4 months | ENT/Facial nerve specialist |
| Suspected alternative diagnosis | As appropriate |
| Eye complications | Ophthalmology |
Surgery
- Surgical decompression: Not routinely recommended (insufficient evidence)
- Cosmetic surgery: For persistent weakness (eyelid weight, facial reanimation)
Immediate
| Complication | Details |
|---|---|
| Exposure keratopathy | Dry eye, corneal abrasion, ulcer |
| Psychosocial impact | Distress, embarrassment |
Late
| Complication | Details |
|---|---|
| Incomplete recovery | Residual weakness (15-30%) |
| Synkinesis | Aberrant reinnervation (e.g., mouth moves when closing eye) |
| Crocodile tears | Lacrimation while eating (aberrant regeneration) |
| Contracture | Tightness of affected side |
| Chronic pain | Post-herpetic neuralgia (more common in Ramsay Hunt) |
Recovery Rates
| Severity | Full Recovery | With Steroids |
|---|---|---|
| Incomplete paralysis | >5% | Excellent |
| Complete paralysis | 60-70% | Improved to 85% |
Timeline
| Timeframe | Expectation |
|---|---|
| Days to 2 weeks | Nadir of weakness |
| 2-4 weeks | Most start to improve |
| 3-6 months | Recovery plateaus |
| No improvement by 4 months | Concerning — refer |
Prognostic Factors
| Good Prognosis | Poor Prognosis |
|---|---|
| Incomplete paralysis | Complete paralysis |
| Early improvement | Older age |
| Young age | Diabetes |
| Early steroid treatment | Delayed treatment |
| Absent stapedial reflex, taste loss |
Key Guidelines
- NICE Clinical Knowledge Summaries: Bell's Palsy — UK guidance.
- AAO-HNSF Clinical Practice Guideline: Bell's Palsy (2013) — American Academy of Otolaryngology.
Landmark Trials
Sullivan et al. (2007) — Early treatment with prednisolone
- 496 patients
- Key finding: Prednisolone within 72h significantly improved recovery (NNT ~6)
- PMID: 17914058
Cochrane Review (2015) — Antivirals for Bell's palsy
- Key finding: Antivirals alone or with steroids provide no additional benefit over steroids alone
- PMID: 26564643
Evidence Strength
| Intervention | Level | Key Evidence |
|---|---|---|
| Prednisolone | 1a | Multiple RCTs, Cochrane |
| Antivirals (Bell's) | 1a | No benefit (Cochrane) |
| Antivirals (Ramsay Hunt) | 2b | Recommended (expert opinion) |
| Eye care | 4 | Expert consensus |
What is Bell's Palsy?
Bell's palsy is a sudden weakness on one side of your face. It happens when the nerve that controls the muscles of your face becomes inflamed and swollen.
What causes it?
The exact cause is not known, but it is thought to be triggered by a viral infection (like the cold sore virus). It is not a stroke.
How is it different from a stroke?
In Bell's palsy, the whole side of your face is weak — including your forehead. In a stroke, your forehead is usually spared. If you are unsure, always seek urgent medical advice.
How is it treated?
- Steroid tablets (prednisolone): Work best if started within 3 days. Reduce inflammation and improve recovery.
- Eye care: Very important. Use artificial tears during the day and ointment at night. Tape your eye closed at night to protect it.
- Antiviral tablets: Not usually needed for Bell's palsy but given if there are blisters in the ear (Ramsay Hunt syndrome).
What to expect
- Most people (70-85%) make a full recovery
- Recovery usually starts within 2-4 weeks
- It may take 3-6 months to fully recover
- Some people have mild weakness or twitching afterwards
When to seek help
See a doctor urgently if:
- You have sudden facial weakness (to confirm the diagnosis)
- Your eye becomes red, painful, or vision changes
- You notice vesicles (blisters) in your ear
Primary Guidelines
- de Almeida JR, et al. Clinical practice guideline: Bell's palsy. Otolaryngol Head Neck Surg. 2014;149(3 Suppl):S1-27. PMID: 25274374
Key Trials
- Sullivan FM, et al. Early treatment with prednisolone or acyclovir in Bell's palsy. N Engl J Med. 2007;357(16):1598-607. PMID: 17914058
- Gagyor I, et al. Antiviral treatment for Bell's palsy (idiopathic facial paralysis). Cochrane Database Syst Rev. 2015;(11):CD001869. PMID: 26564643
Further Resources
- Facial Palsy UK: facialpalsy.org.uk
- NHS Bell's Palsy: nhs.uk/conditions/bells-palsy
Last Reviewed: 2025-12-24 | MedVellum Editorial Team
Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. Clinical decisions should account for individual patient circumstances. Always consult appropriate specialists.