Paediatric Advanced Life Support (PALS)
Paediatric cardiac arrest differs fundamentally from adult arrest. Most paediatric arrests are asphyxial (respiratory in... ACEM Primary Written, ACEM Primary V
Clinical board
A visual summary of the highest-yield teaching signals on this page.
Urgent signals
Safety-critical features pulled from the topic metadata.
- Paediatric cardiac arrest is immediately life-threatening
- Respiratory and circulatory failure precede most paediatric arrests
- Hypoxia is the leading cause - prioritise airway and ventilation
- Bradycardia with poor perfusion is pre-arrest in children
Exam focus
Current exam surfaces linked to this topic.
- ACEM Primary Written
- ACEM Primary Viva
- ACEM Fellowship Written
- ACEM Fellowship OSCE
Linked comparisons
Differentials and adjacent topics worth opening next.
- Adult Cardiac Arrest
- Neonatal Resuscitation
Editorial and exam context
Quick Answer
Critical: Paediatric cardiac arrest requires immediate high-quality CPR with emphasis on oxygenation and ventilation. Survival depends on early recognition of pre-arrest states, rapid initiation of CPR with 5 initial rescue breaths, and prompt identification and treatment of reversible causes.
Paediatric cardiac arrest differs fundamentally from adult arrest. Most paediatric arrests are asphyxial (respiratory in origin), not primary cardiac events. The chain of survival therefore prioritises airway management and oxygenation. ANZCOR Guideline 12 emphasises 5 initial rescue breaths, a 15:2 compression-to-ventilation ratio with two rescuers, and aggressive management of hypoxia. Survival rates are lower than adults for out-of-hospital cardiac arrest (10-30% vs 30-50%), but neurological outcomes in survivors can be good when pre-arrest oxygenation is optimised and early intervention occurs [1,2].
ACEM Exam Focus
Primary Exam Relevance
Anatomy:
- Paediatric airway anatomy (large occiput, large tongue, anterior/cephalad larynx, narrow cricoid ring)
- Vascular access sites (intraosseous insertion points, femoral anatomy)
- Chest wall compliance and cardiac position relative to sternum
- Age-related changes in respiratory mechanics
Physiology:
- Developmental cardiovascular physiology (cardiac output = HR × SV; HR-dependent in children)
- Oxygen consumption in children (6-8 mL/kg/min vs 3-4 mL/kg/min adults)
- Compensatory mechanisms in shock (tachycardia maintained until late decompensation)
- Cerebral autoregulation and vulnerability to hypoxia
Pharmacology:
- Adrenaline pharmacodynamics (alpha and beta adrenoceptor effects)
- Amiodarone mechanism (class III antiarrhythmic, blocks K+ channels)
- Atropine in bradycardia (antimuscarinic)
- Volume of distribution differences in children affecting drug dosing
Fellowship Exam Relevance
Written Examination:
- ANZCOR Guideline 12 algorithm (must know exactly)
- Weight-based drug dosing calculations
- Equipment sizing formulas
- Reversible causes specific to paediatrics
- Post-resuscitation care targets
- Ethical considerations (cessation of resuscitation, family presence)
OSCE Stations:
- Paediatric resuscitation team leadership (core station)
- Bradycardia with poor perfusion management
- Paediatric defibrillation technique demonstration
- Breaking bad news to parents after paediatric death
- Procedural stations (IO insertion, paediatric intubation)
Key Domains Tested:
- Medical Expert: Algorithm knowledge, drug dosing, equipment selection
- Leader: Team leadership, closed-loop communication, resource allocation
- Communicator: Family presence management, breaking bad news
- Collaborator: Multidisciplinary team coordination
Key Points
The 7 things you MUST know for PALS:
- 5 initial rescue breaths - paediatric arrests are usually hypoxic
- 15:2 ratio with two healthcare providers (30:2 single rescuer)
- Adrenaline 10 mcg/kg (0.01 mg/kg) IV/IO every 3-5 minutes
- Defibrillation 4 J/kg for all shocks (no dose escalation)
- IO access is preferred over IV in cardiac arrest when IV not immediately available
- Bradycardia + poor perfusion = pre-arrest - treat aggressively, start CPR if HR below 60
- Reversible causes differ in children (hypoxia #1, sepsis common, shockable rhythms rare)
Definitions and Age Categories
Age Definitions (ANZCOR)
| Category | Age Range | Key Characteristics |
|---|---|---|
| Neonate | Birth to below 28 days | Special resuscitation algorithm (NLS), ANZCOR Guideline 13 |
| Infant | below 1 year | Two-thumb encircling technique preferred, highest arrest risk |
| Child | 1-8 years | One or two-hand compression technique |
| Adolescent | over 8 years or puberty | Adult ALS algorithm applicable |
Normal Vital Signs by Age
| Age | Heart Rate (bpm) | Respiratory Rate | Systolic BP (mmHg) | Hypotension Threshold |
|---|---|---|---|---|
| Neonate | 120-160 | 40-60 | 60-90 | below 60 |
| 1-12 months | 100-160 | 30-50 | 70-100 | below 70 |
| 1-5 years | 95-140 | 25-30 | 80-110 | below 70 + (age × 2) |
| 5-12 years | 80-120 | 20-25 | 90-120 | below 70 + (age × 2) |
| over 12 years | 60-100 | 12-20 | 100-120 | below 90 |
Weight Estimation
| Method | Formula | Application |
|---|---|---|
| APLS formula (1-5 yrs) | Weight (kg) = (Age + 4) × 2 | Age 1-5 years |
| APLS formula (6-12 yrs) | Weight (kg) = (3 × Age) + 7 | Age 6-12 years |
| Infant formula | Weight (kg) = (0.5 × Age in months) + 4 | Under 1 year |
| Broselow tape | Colour-coded length-based | Rapid ED estimation |
| Actual weight | If known | Most accurate - always preferred |
Important Note: Australian Practice Point: The Broselow tape is widely used in Australian EDs but may underestimate weight in Australian children. Use clinical judgement and adjust doses accordingly. When in doubt, use the child's actual weight if available.
Epidemiology
Incidence and Survival
| Metric | Value | Source |
|---|---|---|
| Out-of-hospital cardiac arrest (OHCA) | 8-20 per 100,000 children/year | [3] |
| In-hospital cardiac arrest (IHCA) | 0.7-3% of PICU admissions | [4] |
| OHCA survival to hospital discharge | 10-12% | [5] |
| IHCA survival to hospital discharge | 40-65% | [6] |
| Favourable neurological outcome (OHCA) | 5-15% | [7] |
| Peak incidence age | below 1 year (infants) | [8] |
| Male:Female ratio | 1.3:1 | [9] |
Aetiology by Age
| Age Group | Common Causes |
|---|---|
| Neonates | Birth asphyxia, congenital heart disease, sepsis |
| Infants (below 1 yr) | SIDS/SUDI, respiratory infections, trauma (NAI), congenital heart disease |
| 1-4 years | Drowning, trauma, respiratory infections, foreign body aspiration |
| 5-12 years | Trauma, drowning, cardiac causes (channelopathies), infections |
| Adolescents | Trauma, cardiac (channelopathies, HCM, ARVC), overdose/poisoning |
Primary Causes of Paediatric Cardiac Arrest
| Cause | Percentage | Key Features |
|---|---|---|
| Respiratory | 60-70% | Hypoxia, aspiration, pneumonia, bronchiolitis, asthma, foreign body |
| Circulatory | 15-20% | Sepsis, hypovolaemia (gastroenteritis, haemorrhage), anaphylaxis |
| Cardiac | 5-15% | Arrhythmia, structural heart disease, channelopathies |
| Sudden unexplained | 5-10% | SIDS/SUDI, channelopathies (Long QT, Brugada) |
| Trauma | 5-10% | Head injury, haemorrhage, drowning |
Australian/New Zealand Specific Data
- Drowning is a leading cause of paediatric OHCA in Australia (2nd behind trauma) [10]
- Indigenous children have higher rates of OHCA, particularly from respiratory infections and trauma [11]
- Rural/remote areas have delayed EMS response times significantly impacting survival
- Temperature considerations: hypothermia in southern states, hyperthermia in northern regions
- Marine envenomation in coastal areas (box jellyfish, Irukandji) - rare but important
Indigenous Health Considerations
Important Note: Aboriginal, Torres Strait Islander, and Māori Considerations:
Health Disparities:
- Higher rates of acute respiratory infections requiring hospitalisation
- Increased risk of complications from acute gastroenteritis (dehydration, shock)
- Higher rates of rheumatic heart disease affecting cardiac function
- Higher rates of SUDI in Indigenous infants
- Limited access to paediatric tertiary care in remote communities
Cultural Considerations:
- Extended family (kinship) involvement in decision-making is critical
- Kinship structures may mean non-biological parents are primary carers
- Cultural protocols around children's illness and death must be respected
- Language barriers may exist even with English-speaking families
- Sorry Business protocols if death occurs
- Connection to Country and community is important
Practical Actions:
- Aboriginal Liaison Officers/Māori Health Workers should be notified early
- Interpreter services for language groups
- Extended whānau/family may need to be present and involved
- Cultural protocols for death may include specific practices
- Referral to Indigenous-specific grief support services
- Trauma-informed care approach given historical experiences
New Zealand - Māori Considerations:
- Whānau (extended family) involvement in all decision-making
- Karakia (prayers) may be requested at beginning and end
- Kaumātua (elders) involvement where possible
- Te Whare Tapa Whā model (physical, mental, family, spiritual dimensions)
Pathophysiology
Why Paediatric Arrests Differ from Adult Arrests
Respiratory Predominance: Children have higher oxygen consumption (6-8 mL/kg/min vs 3-4 mL/kg/min in adults), smaller functional residual capacity, higher airway resistance, and less respiratory reserve. Hypoxia develops rapidly during apnoea - faster than in adults.
Cardiovascular Considerations:
- Cardiac output in children is heart rate dependent (limited ability to increase stroke volume)
- Bradycardia is therefore a pre-terminal sign indicating severe hypoxia or impending arrest
- Children maintain blood pressure until late in shock (compensated → decompensated rapidly)
- Hypotension is a LATE sign - indicates loss of 25-40% blood volume or severe compromise
Progression to Cardiac Arrest
Respiratory Distress → Respiratory Failure → Cardiopulmonary Failure → Cardiac Arrest
↓ ↓ ↓ ↓
Tachypnoea Hypoxaemia Bradycardia Asystole/PEA
Accessory muscles Altered consciousness Hypotension (VF/pVT rare)
Nasal flaring Exhaustion Poor perfusion
Grunting Bradypnoea Acidosis
Arrest Rhythms in Children
| Rhythm | Frequency | Typical Aetiology |
|---|---|---|
| Asystole | 40-50% | End-stage hypoxia, prolonged arrest |
| PEA | 30-40% | Hypoxia, hypovolaemia, tension pneumothorax, tamponade |
| VF/pVT | 5-15% (up to 25% in witnessed IHCA) | Primary cardiac, channelopathy, toxins, electrolytes |
| Bradycardia | Pre-arrest | Hypoxia, vagal stimulation |
Key Insight: VF/pVT is more common in witnessed IHCA (up to 25%) and in children with known cardiac disease. Always consider shockable rhythms in adolescents, drowning with hypothermia, and known cardiac patients. VF is treatable if recognised early.
Recognition of the Deteriorating Child
Pre-Arrest Warning Signs
Immediate Intervention Required If Present:
- Heart rate below 60/min with poor perfusion (infant) or below 50/min (child)
- Irregular respiratory pattern, gasping, or apnoea
- Central cyanosis despite high-flow oxygen
- Unresponsive or responds only to painful stimuli
- Absent central pulses or CRT over 5 seconds
- Bradypnoea with reduced effort in previously distressed child (exhaustion)
Paediatric Assessment Triangle (PAT)
Rapid "from the doorway" assessment (10-15 seconds):
| Domain | Assessment | Abnormal Signs |
|---|---|---|
| Appearance | Tone, interactivity, consolability, look/gaze, speech/cry | Floppy, uninterested, inconsolable, vacant stare, weak cry |
| Work of Breathing | Effort, abnormal sounds, position | Retractions, stridor, grunting, tripod position |
| Circulation | Skin colour | Pallor, mottling, cyanosis |
Systematic ABCDE Assessment
Airway
| Assessment | Normal | Abnormal |
|---|---|---|
| Patency | Clear, silent breathing | Stridor, stertor, snoring, complete obstruction |
| Position | Self-maintaining | Unable to maintain, drooling, tripod |
| Secretions | None | Copious, blood |
Breathing
| Assessment | Signs of Distress | Signs of Failure |
|---|---|---|
| Rate | Tachypnoea | Bradypnoea (ominous) |
| Work | Retractions, grunting, nasal flaring | Reduced effort with exhaustion |
| SpO₂ | below 94% on room air | below 90% on high-flow oxygen |
| Auscultation | Wheeze, crackles | Silent chest, absent breath sounds |
Circulation
| Assessment | Compensated Shock | Decompensated Shock |
|---|---|---|
| Heart rate | Tachycardia | Tachy- or bradycardia |
| Pulse quality | Normal or bounding | Weak, thready |
| Capillary refill | 2-3 seconds | over 3-4 seconds |
| Skin | Pale, cool peripheries | Mottled, cyanotic |
| Blood pressure | Normal | Hypotension (LATE) |
| Urine output | Reduced | Minimal/absent |
Disability
| Assessment | Method |
|---|---|
| Consciousness | AVPU (Alert, Voice, Pain, Unresponsive) |
| Pupils | Size, equality, reactivity |
| Posture | Normal, decorticate, decerebrate |
| Glucose | Always check in altered consciousness |
Exposure
- Full exposure (maintain dignity)
- Core temperature measurement
- Rash assessment (petechiae/purpura = meningococcal)
- Signs of trauma or NAI
- Prevent hypothermia (children lose heat rapidly)
ANZCOR Guideline 12: Paediatric Advanced Life Support Algorithm
Paediatric Basic Life Support Foundation
┌─────────────────────────────────────────────────────────────────────────────┐
│ DANGER │
│ Check for hazards to self and child │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ RESPONSE │
│ Stimulate child - call name, tap shoulders/feet │
│ If unresponsive → Send for help (call 000, activate MET) │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ AIRWAY │
│ Open airway: head tilt-chin lift │
│ Neutral position in infant, slight extension in child │
│ Remove visible obstruction (only if clearly visible) │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ CHECK BREATHING (10 seconds max) │
│ Look for chest movement │
│ Listen for breath sounds │
│ Feel for air movement │
│ │
│ If NOT breathing normally or only gasping → Give 5 RESCUE BREATHS │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ 5 INITIAL RESCUE BREATHS │
│ Give 5 breaths - each over 1 second with visible chest rise │
│ Infant: mouth-to-mouth-and-nose or BVM with appropriate mask │
│ Child: mouth-to-mouth or BVM with appropriate mask │
│ If chest not rising: reposition airway, reattempt │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ CHECK FOR SIGNS OF LIFE (10 seconds max) │
│ Healthcare providers: Check central pulse │
│ - Brachial artery (infant) or Carotid artery (child) │
│ - Simultaneously assess for movement, coughing, breathing │
│ │
│ If no signs of life OR HR below 60/min with poor perfusion → START CPR │
└─────────────────────────────────────────────────────────────────────────────┘
Paediatric CPR Technique
┌─────────────────────────────────────────────────────────────────────────────┐
│ PAEDIATRIC CPR │
│ │
│ COMPRESSION SITE: │
│ • Infant: Lower third of sternum, just below nipple line │
│ • Child: Lower half of sternum, between nipples │
│ │
│ COMPRESSION TECHNIQUE: │
│ • Infant (2 rescuers): Two-thumb encircling technique (PREFERRED) │
│ - Both thumbs on sternum, fingers encircle chest supporting back │
│ • Infant (1 rescuer): Two-finger technique │
│ - Two fingers on lower sternum │
│ • Child: One or two hands on lower half of sternum │
│ - Heel of hand(s), fingers interlocked or lifted off chest │
│ │
│ DEPTH: Compress to 1/3 of anterior-posterior chest diameter │
│ Infant: approximately 4 cm │
│ Child: approximately 5 cm │
│ │
│ RATE: 100-120 compressions per minute │
│ │
│ RATIO: │
│ • 15:2 (two healthcare providers) - PREFERRED │
│ • 30:2 (single rescuer or lay rescuers) │
│ │
│ QUALITY: │
│ • Allow full chest recoil between compressions │
│ • Minimise interruptions (below 10 seconds) │
│ • Rotate compressors every 2 minutes to prevent fatigue │
└─────────────────────────────────────────────────────────────────────────────┘
ANZCOR Paediatric ALS Algorithm
Attach defibrillator/monitor
↓
ASSESS RHYTHM
↓
┌──────────────────┴──────────────────┐
↓ ↓
┌────────────────────────────┐ ┌────────────────────────────────────────┐
│ SHOCKABLE RHYTHM │ │ NON-SHOCKABLE RHYTHM │
│ VF / Pulseless VT │ │ Asystole / PEA │
└────────────────────────────┘ └────────────────────────────────────────┘
↓ ↓
┌────────────────────────────┐ ┌────────────────────────────────────────┐
│ DEFIBRILLATION │ │ │
│ 4 J/kg (ALL shocks) │ │ Resume CPR immediately │
│ │ │ 2 minutes (5 cycles of 15:2) │
│ Resume CPR immediately │ │ │
│ after shock - 2 minutes │ │ Adrenaline 10 mcg/kg IV/IO │
│ │ │ as soon as access obtained │
│ DO NOT pause to check │ │ then every 3-5 minutes │
│ rhythm after shock │ │ │
└────────────────────────────┘ │ Consider and treat reversible causes │
↓ │ (4Hs and 4Ts) │
┌────────────────────────────┐ │ │
│ DRUG TIMING: │ │ Consider advanced airway if │
│ │ │ trained operator available │
│ After 2nd shock: │ │ │
│ • Adrenaline 10 mcg/kg │ └────────────────────────────────────────┘
│ │ ↓
│ After 3rd shock: │ ┌────────────────────────────────────────┐
│ • Amiodarone 5 mg/kg │ │ After 2 minutes: │
│ │ │ • Reassess rhythm │
│ After 5th shock: │ │ • If still non-shockable: repeat │
│ • Consider 2nd dose │ │ adrenaline, continue CPR │
│ amiodarone 5 mg/kg │ │ • If becomes shockable: switch │
│ │ │ to shockable algorithm │
│ Adrenaline every 3-5 min │ └────────────────────────────────────────┘
│ thereafter │
└────────────────────────────┘
↓
└──────────────────┬───────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ DURING CPR - CHECKLIST │
│ │
│ □ High-quality CPR: correct rate, depth, full recoil, minimise pauses │
│ □ Obtain vascular access (IO preferred if IV not immediately available) │
│ □ Confirm weight and calculate drug doses │
│ □ Give adrenaline every 3-5 minutes │
│ □ Consider advanced airway when skilled operator available │
│ □ Continuous waveform capnography if intubated (target ETCO₂ greater than 10 mmHg) │
│ □ Treat reversible causes systematically (4Hs and 4Ts) │
│ □ Rotate compressors every 2 minutes │
│ □ Consider family presence with dedicated support person │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ RETURN OF SPONTANEOUS CIRCULATION (ROSC) │
│ │
│ Signs: Palpable pulse, rise in ETCO₂ (usually greater than 40 mmHg), arterial │
│ waveform, spontaneous movement, coughing, breathing │
│ │
│ → Proceed to POST-RESUSCITATION CARE │
└─────────────────────────────────────────────────────────────────────────────┘
Compression Techniques by Age
Infant (under 1 year)
Two-Thumb Encircling Technique (PREFERRED for 2 rescuers):
- Place both thumbs side-by-side on lower third of sternum (just below nipple line)
- Thumbs may overlap in very small infants
- Encircle chest with fingers supporting the back
- Compress with thumbs to 1/3 AP diameter (~4 cm)
- Rate: 100-120/min
- This technique generates superior coronary perfusion pressure [12]
Two-Finger Technique (Single rescuer alternative):
- Place 2 fingers (index and middle) on lower third of sternum
- One finger-breadth below nipple line
- Other hand supports head/maintains airway position
- Compress to 1/3 AP diameter (~4 cm)
- Rate: 100-120/min
Child (1-8 years)
One-Hand Technique:
- Heel of one hand on lower half of sternum (between nipples)
- Lift fingers to avoid compressing ribs
- Avoid xiphoid process
- Compress to 1/3 AP diameter (~5 cm)
- Rate: 100-120/min
Two-Hand Technique (larger children):
- Heel of one hand on lower half of sternum
- Second hand on top, fingers interlocked
- Arms straight, compress vertically
- Compress to 1/3 AP diameter (~5 cm)
- Rate: 100-120/min
CPR Quality Metrics
| Parameter | Target | Monitoring |
|---|---|---|
| Rate | 100-120/min | Metronome, CPR feedback device |
| Depth | 1/3 AP diameter | Visual assessment, feedback device |
| Recoil | Full chest recoil | Avoid leaning on chest |
| Fraction | over 80% compressions | Minimise all pauses |
| Ventilation | Visible chest rise | Avoid hyperventilation |
| ETCO₂ | over 10 mmHg during CPR | Indicates adequate cardiac output |
Vascular Access
Priority Hierarchy (ANZCOR)
ANZCOR Recommendation: In paediatric cardiac arrest, intraosseous (IO) access is the preferred first-line vascular access when peripheral IV is not immediately available. Do not delay drug administration waiting for IV access - place an IO.
| Priority | Access Type | Maximum Attempt Time | Notes |
|---|---|---|---|
| 1st | Existing IV access | N/A | Use immediately |
| 2nd | Intraosseous (IO) | Place within 60 seconds | First-line if no IV |
| 3rd | Peripheral IV | 90 seconds max / 2 attempts | Don't delay if failing |
| 4th | Central venous access | Not during CPR | Specialist procedure |
| 5th | Endotracheal drugs | Last resort | 10× dose, suboptimal absorption |
Intraosseous Access Sites
| Site | Landmark | Technique | Age Suitability |
|---|---|---|---|
| Proximal tibia (preferred) | 1-2 cm below tibial tuberosity, medial flat surface | Perpendicular to bone, away from growth plate | All ages |
| Distal tibia | 1-2 cm above medial malleolus, flat medial surface | Perpendicular, slightly cephalad | All ages |
| Distal femur | 1-2 cm above lateral femoral condyle, midline anterior | Cephalad angulation 10-15° | Infants, young children |
| Humeral head | Greater tubercle, lateral shoulder | 45° to anterior, 45° inferiorly | Adolescents, adults |
Insertion Technique:
- Identify landmarks, stabilise limb, clean skin
- Insert needle perpendicular to bone (away from growth plate)
- Advance with rotating motion until "give" or "pop" felt (cortex penetrated)
- Remove stylet
- Aspirate (may not always yield marrow - NOT required for confirmation)
- Flush with 5-10 mL normal saline - should flow freely without extravasation
- Secure and commence drug/fluid administration
IO Needle Sizes:
- Manual: 15-18G for all paediatric ages
- EZ-IO powered: Pink needle (3-39 kg), Blue needle (≥40 kg)
Contraindications:
- Fracture in target bone or proximal to site
- Previous IO in same bone within 48 hours
- Infection at insertion site
- Osteogenesis imperfecta or other bone fragility
- Previous orthopaedic hardware at site
Equipment Sizing
Endotracheal Tube Sizing
Cuffed ETT (now acceptable for ALL ages including neonates):
| Formula | Calculation |
|---|---|
| Size (mm ID) | Age/4 + 3.5 |
| Example (4 years) | 4/4 + 3.5 = 4.5 mm |
Uncuffed ETT (traditional):
| Formula | Calculation |
|---|---|
| Size (mm ID) | Age/4 + 4 |
| Example (4 years) | 4/4 + 4 = 5.0 mm |
Important Note: Current ANZCOR Guidance: Cuffed ETT are now acceptable for all ages including neonates. Cuffed tubes may reduce aspiration risk and need for tube exchange. Maintain cuff pressure below 20-25 cmH₂O to avoid mucosal damage.
Insertion Depth (Oral):
| Formula | Calculation |
|---|---|
| Depth at lips (cm) | Age/2 + 12 |
| Alternative | Internal diameter × 3 |
Age-Based Equipment Sizing Table
| Age | Weight (kg) | ETT Size (cuffed) | ETT Depth (lip) | Laryngoscope | LMA Size | Suction |
|---|---|---|---|---|---|---|
| Preterm | 1-2.5 | 2.5-3.0 | 6-7 cm | Miller 0 | 1 | 6F |
| Term neonate | 3-4 | 3.0-3.5 | 8-9 cm | Miller 0-1 | 1 | 8F |
| 6 months | 6-8 | 3.5 | 10 cm | Miller 1 | 1.5 | 8F |
| 1 year | 10 | 4.0 | 11 cm | Miller 1-2 | 1.5-2 | 8-10F |
| 2 years | 12 | 4.0-4.5 | 12 cm | Miller/Mac 2 | 2 | 10F |
| 4 years | 16 | 4.5-5.0 | 13 cm | Mac 2 | 2-2.5 | 10F |
| 6 years | 20 | 5.0-5.5 | 14 cm | Mac 2 | 2.5 | 10-12F |
| 8 years | 25 | 5.5-6.0 | 15 cm | Mac 2-3 | 2.5-3 | 12F |
| 10 years | 30 | 6.0-6.5 | 16 cm | Mac 3 | 3 | 12F |
| 12 years | 40 | 6.5-7.0 | 17 cm | Mac 3 | 3-4 | 12-14F |
Defibrillator Pad Selection
| Weight/Age | Pad Type | Placement |
|---|---|---|
| below 10 kg (or below 1 year) | Paediatric pads if available | Anterior-posterior (preferred) |
| ≥10 kg (or over 1 year) | Adult pads | Anterior-posterior or sternal-apex |
| Adult pads on infant | Acceptable if paediatric unavailable | Anterior-posterior to avoid overlap |
Practical Tip: If only adult pads are available for infants/small children, place in anterior-posterior position (one pad on front of chest, one on back) to avoid pad overlap. Adult pads can safely be used at any age - do not delay defibrillation.
Defibrillation
Energy Dosing (ANZCOR)
| Shock | Energy | Notes |
|---|---|---|
| ALL shocks | 4 J/kg | No dose escalation in ANZCOR guidelines |
| Maximum | 360 J (monophasic) / 200 J (biphasic) | Adult maximum applies |
| AED paediatric mode | Attenuated dose (50-75 J) | Use if available for under 8 years / below 25 kg |
| AED without paediatric mode | Standard adult dose | Acceptable - do not delay |
Key Differences from AHA
| Element | ANZCOR | AHA |
|---|---|---|
| First shock | 4 J/kg | 2 J/kg |
| Subsequent shocks | 4 J/kg | 4 J/kg |
| Dose escalation | No | Yes (2→4 J/kg) |
Defibrillation Technique
- Continue CPR while preparing defibrillator
- Apply pads - select paediatric pads if available and below 10 kg
- Position pads - anterior-posterior preferred in small children
- Ensure pads do not touch or overlap
- Set energy to 4 J/kg (calculate based on weight)
- Charge while compressions continue
- Clear check - "I'm clear, you're clear, everyone's clear"
- visual check
- Deliver shock with minimal hands-off time (below 5 seconds)
- Immediately resume CPR for 2 minutes - do NOT pause to check rhythm
Defibrillation in Special Circumstances
Hypothermia (core temp below 30°C):
- Give up to 3 shocks if VF persists
- If remains in VF after 3 shocks: withhold further shocks until rewarmed to over 30°C
- Continue CPR and active rewarming
- Resume shocks once core temp over 30°C
Pacemaker/ICD in situ:
- Place pads at least 8 cm from device
- Anterior-posterior placement preferred
- Check device function post-resuscitation
Medications in Paediatric Cardiac Arrest
Adrenaline (Epinephrine)
| Parameter | Value |
|---|---|
| Dose | 10 mcg/kg (0.01 mg/kg) |
| Concentration | 1:10,000 (0.1 mg/mL) |
| Volume | 0.1 mL/kg of 1:10,000 |
| Maximum single dose | 1 mg |
| Route | IV or IO (preferred) |
| Timing - Non-shockable | As soon as IV/IO access obtained, then every 3-5 min |
| Timing - Shockable | After 2nd shock, then every 3-5 min (alternate cycles) |
| ETT dose (if no IV/IO) | 100 mcg/kg (0.1 mg/kg) - 10× IV dose |
Weight-Based Adrenaline Dosing Table
| Weight (kg) | Adrenaline Dose | Volume (1:10,000) |
|---|---|---|
| 3 | 30 mcg | 0.3 mL |
| 5 | 50 mcg | 0.5 mL |
| 7 | 70 mcg | 0.7 mL |
| 10 | 100 mcg | 1.0 mL |
| 12 | 120 mcg | 1.2 mL |
| 15 | 150 mcg | 1.5 mL |
| 20 | 200 mcg | 2.0 mL |
| 25 | 250 mcg | 2.5 mL |
| 30 | 300 mcg | 3.0 mL |
| 40 | 400 mcg | 4.0 mL |
| 50 | 500 mcg | 5.0 mL |
| ≥100 | 1000 mcg (1 mg) | 10 mL (max) |
Amiodarone
| Parameter | Value |
|---|---|
| Dose | 5 mg/kg |
| Maximum single dose | 300 mg |
| Route | IV or IO (bolus in cardiac arrest) |
| Timing | After 3rd shock in refractory VF/pVT |
| Second dose | 5 mg/kg can be repeated after 5th shock |
| Dilution | May dilute in 5% dextrose if peripheral IV |
Weight-Based Amiodarone Dosing Table
| Weight (kg) | Amiodarone Dose (5 mg/kg) | Volume (50 mg/mL) |
|---|---|---|
| 5 | 25 mg | 0.5 mL |
| 10 | 50 mg | 1.0 mL |
| 15 | 75 mg | 1.5 mL |
| 20 | 100 mg | 2.0 mL |
| 25 | 125 mg | 2.5 mL |
| 30 | 150 mg | 3.0 mL |
| 40 | 200 mg | 4.0 mL |
| 50 | 250 mg | 5.0 mL |
| ≥60 | 300 mg (max) | 6.0 mL |
Other Medications in Paediatric Resuscitation
| Drug | Indication | Dose | Route | Notes |
|---|---|---|---|---|
| Atropine | Bradycardia (vagal cause) | 20 mcg/kg | IV/IO | Min 100 mcg, max 600 mcg (child), 1 mg (adolescent) |
| Calcium chloride 10% | Hypocalcaemia, hyperkalaemia, Ca-blocker OD | 0.2 mL/kg (20 mg/kg) | IV/IO slow | Irritant - give slowly |
| Magnesium sulfate | Hypomagnesaemia, torsades de pointes | 25-50 mg/kg | IV/IO | Max 2 g, give over 10-20 min |
| Sodium bicarbonate 8.4% | Hyperkalaemia, TCA OD, prolonged arrest | 1 mmol/kg (1 mL/kg) | IV/IO | Only if specific indication |
| Glucose 10% | Documented hypoglycaemia | 0.5 g/kg (5 mL/kg of 10%) | IV/IO | Check BSL regularly |
| Adenosine | SVT (not cardiac arrest) | 100 → 200 → 300 mcg/kg | IV rapid push | Max 6 mg, 12 mg, 12 mg |
Reversible Causes (4Hs and 4Ts)
Paediatric-Focused 4Hs
| Cause | Paediatric Relevance | Recognition | Treatment |
|---|---|---|---|
| Hypoxia | #1 cause in paediatrics | History (choking, drowning), SpO₂, cyanosis, witnessed apnoea | High-flow oxygen, BVM ventilation, advanced airway, remove FB |
| Hypovolaemia | Gastroenteritis, trauma, sepsis, DKA | Tachycardia, poor perfusion, history of losses | 20 mL/kg crystalloid bolus, blood products if haemorrhage |
| Hypokalaemia/Hyperkalaemia | DKA, renal disease, drugs, gastro losses | ECG (peaked T/flat T, wide QRS), history | Calcium chloride, insulin/dextrose, salbutamol, dialysis |
| Hypothermia | Drowning, exposure, near-SIDS | Core temperature, cold exposure history | Active rewarming, prolonged resuscitation |
Paediatric-Focused 4Ts
| Cause | Paediatric Relevance | Recognition | Treatment |
|---|---|---|---|
| Tension pneumothorax | Trauma, asthma, ventilation | Unilateral chest movement, tracheal deviation, absent BS | Needle decompression → finger thoracostomy → ICC |
| Tamponade | Trauma (penetrating), malignancy | Muffled heart sounds, distended neck veins, PEA | Pericardiocentesis, emergency thoracotomy |
| Toxins | Accidental ingestion common | History, toxidrome, medication access | Specific antidotes, supportive care, Poisons 13 11 26 |
| Thrombosis | Rare - central lines, Kawasaki, Fontan | History, risk factors, ECG changes | Thrombolysis, ECMO consideration |
Additional Paediatric-Specific Causes
| Cause | Recognition | Treatment |
|---|---|---|
| Congenital heart disease | Known history, cyanosis, murmur, SpO₂ below 85% | Prostaglandin E1 for duct-dependent lesions, specialist input |
| Sepsis | Fever/hypothermia, mottled, poor perfusion | Fluids 20 mL/kg, antibiotics within 1 hour, inotropes |
| SIDS/SUDI | Unexplained, infant found unresponsive | Full resuscitation, forensic considerations, family support |
| Non-accidental injury | Inconsistent history, unusual injuries | Full resuscitation, documentation, mandatory reporting |
| Foreign body obstruction | Witnessed, sudden onset, coughing/cyanosis | FBAO algorithm, laryngoscopy, Magill forceps |
Bradycardia with Poor Perfusion Algorithm
Recognition
- Heart rate below 60/min with poor perfusion in infant
- Heart rate below 50/min with poor perfusion in child
- AND signs of poor perfusion:
- Altered consciousness / lethargy
- Weak or absent peripheral pulses
- Poor capillary refill (greater than 3 seconds)
- Mottled skin, pallor
Management Algorithm
┌─────────────────────────────────────────────────────────────────────────────┐
│ BRADYCARDIA WITH PULSE BUT POOR PERFUSION │
│ │
│ HR below 60 (infant) or below 50 (child) WITH signs of poor perfusion │
│ │
│ 1. Support ABCs - give oxygen │
│ 2. Attach monitor/defibrillator │
│ 3. Identify and treat underlying cause (MOST LIKELY HYPOXIA) │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ DOES BRADYCARDIA PERSIST DESPITE ADEQUATE OXYGENATION/VENTILATION? │
│ │
│ If YES and HR below 60/min with poor perfusion despite oxygen/ventilation: │
│ │
│ → START CPR │
│ │
│ (Bradycardia with poor perfusion = indication for CPR even with pulse) │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ ADRENALINE │
│ • 10 mcg/kg (0.01 mg/kg) IV/IO │
│ • Repeat every 3-5 minutes if bradycardia persists │
│ │
│ ATROPINE (if vagal cause suspected) │
│ • Vagal causes: intubation, suctioning, gastric distension │
│ • 20 mcg/kg IV/IO (minimum 100 mcg, max 600 mcg child, 1 mg adolescent) │
│ • May repeat once │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ REASSESS AFTER EACH INTERVENTION │
│ │
│ If HR improves greater than 60 and perfusion improves → stop CPR, monitor │
│ │
│ If develops pulseless arrest → full cardiac arrest algorithm │
│ │
│ CONSIDER: │
│ • Transcutaneous pacing (if available and heart block suspected) │
│ • Expert consultation (cardiology, PICU) │
│ • Continue to treat reversible causes │
└─────────────────────────────────────────────────────────────────────────────┘
Tachycardia Algorithms
Narrow Complex Tachycardia (QRS ≤0.09s)
Step 1: Assess Haemodynamic Stability
| Stable | Unstable |
|---|---|
| Conscious, alert | Altered consciousness |
| Adequate perfusion | Poor perfusion (mottling, weak pulses) |
| Normal blood pressure | Hypotension |
| Can trial vagal/adenosine | Requires immediate cardioversion |
Stable SVT Management:
-
Vagal Manoeuvres (first-line):
- Infant: Ice pack to face for 5-10 seconds (cover nose and mouth briefly)
- Child: Valsalva manoeuvre (blowing into syringe, blowing up balloon)
- Modified Valsalva (strain then lie flat with legs raised)
-
Adenosine (if vagal manoeuvres fail):
| Dose | Amount | Maximum |
|---|---|---|
| 1st dose | 100 mcg/kg | 6 mg |
| 2nd dose | 200 mcg/kg | 12 mg |
| 3rd dose | 300 mcg/kg | 12 mg |
Technique: Rapid IV push through large-bore proximal IV, immediately followed by 10-20 mL rapid saline flush. Record rhythm strip during administration.
Unstable SVT:
- Synchronised cardioversion 0.5-1 J/kg → 2 J/kg if fails
- Sedate if time permits and patient conscious (ketamine 1-2 mg/kg IV)
- Ensure synchronisation mode is ON
Wide Complex Tachycardia (QRS greater than 0.09s)
Assume VT until proven otherwise
Pulseless or uncertain pulse: Treat as VF - defibrillation 4 J/kg
VT with Pulse - Unstable:
- Synchronised cardioversion 1-2 J/kg → 2-4 J/kg
- Sedate if conscious and time permits
VT with Pulse - Stable:
- Amiodarone 5 mg/kg IV over 20-60 minutes
- Expert consultation (paediatric cardiology)
- Prepare for cardioversion if deteriorates
Airway Management in PALS
Age-Specific Considerations
| Age | Head Position | Anatomical Considerations |
|---|---|---|
| Infant | Neutral ("sniffing") | Large occiput - may need shoulder roll, large tongue, anterior larynx |
| Child | Slight extension | Transition anatomy |
| Adolescent | "Sniffing" position | Adult anatomy |
Bag-Valve-Mask Ventilation
Mask Sizing: Apex at bridge of nose, base between lower lip and chin
Technique:
- E-C clamp grip on mask (2-person technique preferred)
- Position head appropriately for age
- Deliver breath over 1 second
- Watch for chest rise (avoid excessive volumes)
- Rate: 12-20 breaths/min (younger = faster)
Troubleshooting "BONES":
- B: Bag not working or connected
- O: Obstruction (secretions, FB, tongue, laryngospasm)
- N: No seal (reposition mask, two-person technique)
- E: Equipment failure (check oxygen, bag)
- S: Stomach distension (reposition, consider NG)
Advanced Airway Considerations
When to Consider Intubation:
- Unable to ventilate adequately with BVM
- Prolonged resuscitation anticipated
- Transport with ongoing CPR
- Post-ROSC without protective airway reflexes
If Intubated:
- Ventilate at 10 breaths/min (1 breath every 6 seconds)
- Do NOT synchronise with compressions
- Do NOT pause compressions for ventilation
- Target ETCO₂ over 10 mmHg during CPR (indicates adequate CO)
- ETCO₂ over 40 mmHg may indicate ROSC
Post-Resuscitation Care
Immediate Post-ROSC Priorities
| Priority | Target | Intervention |
|---|---|---|
| Oxygenation | SpO₂ 94-98% | Titrate FiO₂ - avoid hyperoxia |
| Ventilation | PaCO₂ 35-45 mmHg | Adjust rate/tidal volume - avoid hypo/hypercapnia |
| Circulation | Age-appropriate BP, MAP ≥5th centile | Fluids, vasoactive drugs as needed |
| Disability | Glucose 6-10 mmol/L, treat seizures | Avoid hypo/hyperglycaemia, anticonvulsants if seizing |
| Temperature | 36-37.5°C or TTM 32-34°C | Actively prevent fever, consider TTM |
Targeted Temperature Management (TTM)
Current ANZCOR/ILCOR Guidance (2020):
- Actively prevent fever (≥37.5°C) for at least 72 hours post-ROSC - this is standard care
- Consider TTM at 32-34°C for comatose children after OHCA or IHCA
- Duration: 24-72 hours of active temperature management
- Setting: TTM should be initiated and managed in PICU
- Evidence: THAPCA trials showed no difference between 33°C and 36.8°C for neurological outcome, but avoiding fever is beneficial [13,14]
Investigations Post-ROSC
| Immediate | Purpose |
|---|---|
| 12-lead ECG | Rhythm, QTc, signs of ischaemia, channelopathy |
| ABG/VBG | Acid-base, lactate, electrolytes |
| Chest X-ray | ETT position, cardiac size, aspiration, pneumothorax |
| Blood glucose | Point-of-care, then laboratory |
| FBC, U&E, LFT, coags | Organ function assessment |
| Troponin | Cardiac biomarker if cardiac aetiology suspected |
| Toxicology screen | If poisoning suspected |
Disposition
| Clinical Scenario | Disposition |
|---|---|
| All survivors of cardiac arrest | PICU admission mandatory |
| Haemodynamically unstable post-ROSC | PICU with vasoactive support |
| Suspected cardiac aetiology | Paediatric cardiology referral, consider tertiary transfer |
| Non-survivable injury or prolonged arrest | Palliative care / withdrawal discussion in ED (with family) |
Family Presence During Resuscitation
ANZCOR/ILCOR Position
Important Note: Best Practice: Family members should be offered the opportunity to be present during resuscitation of their child. Evidence demonstrates that family presence:
- Does NOT interfere with resuscitation [15]
- Does NOT increase provider stress
- Reduces anxiety and depression in family members
- Facilitates the grieving process if death occurs
- Should be supported by a designated staff member
- Is valued by most families
Practical Implementation
| Element | Approach |
|---|---|
| Assign support person | Dedicated staff member stays with family throughout |
| Positioning | Place family where they can see but not impede resuscitation |
| Explanation | Provide ongoing narration of what is happening in plain language |
| Physical contact | Encourage family to touch child's hand/foot if safe and appropriate |
| Cultural needs | Ask about any cultural or religious requirements |
| Decision-making | Include family in discussions about cessation when appropriate |
| Prepare for outcome | Gently prepare family for possibility of death |
| Post-event support | Arrange chaplaincy, social work, bereavement support |
Cessation of Resuscitation
Considerations for Stopping
There is no absolute time limit for paediatric resuscitation. Factors to consider:
| Factor | Implication |
|---|---|
| Witnessed vs unwitnessed | Unwitnessed arrest with prolonged down-time has poor prognosis |
| Initial rhythm | Non-shockable rhythms have worse prognosis than VF/pVT |
| Response to interventions | No ROSC after 20-30+ minutes of optimal ALS |
| Underlying cause | Treatable causes (toxins, hypothermia) warrant prolonged efforts |
| Pre-existing conditions | Consider prior quality of life and any advance care plans |
| ETCO₂ | Persistently below 10 mmHg indicates poor cardiac output/futility |
| Arrest duration | Prolonged arrest (over 30 min) associated with poor neurological outcome |
Special Circumstances Requiring Prolonged Resuscitation
- Hypothermia: Continue until rewarmed to ≥32°C ("not dead until warm and dead")
- Toxicological: May respond after prolonged resuscitation (especially sodium channel blockers)
- Drowning in cold water: Young children may have good outcomes even after prolonged submersion
- ECPR consideration: Refer to ECMO-capable centre if available and appropriate criteria met [16]
Shock Recognition and Management
Types of Shock in Children
| Type | Causes | Features | Management |
|---|---|---|---|
| Hypovolaemic | Gastroenteritis, haemorrhage, burns | Tachycardia, dry mucous membranes, reduced urine | Fluid boluses 20 mL/kg, blood if haemorrhage |
| Distributive (Septic) | Infection | Warm peripheries early, then cool; fever/hypothermia | Fluids, antibiotics within 1 hour, vasoactive drugs |
| Cardiogenic | Myocarditis, CHD, arrhythmia | Hepatomegaly, gallop rhythm, poor response to fluids | Smaller fluid volumes (5-10 mL/kg), inotropes, cardiology |
| Obstructive | Tension pneumothorax, tamponade, PE | Elevated JVP, pulsus paradoxus | Treat underlying cause urgently |
Fluid Resuscitation in Shock
┌─────────────────────────────────────────────────────────────────────────────┐
│ SHOCK IDENTIFIED │
│ (Tachycardia, poor perfusion, ± hypotension) │
│ │
│ 1. High-flow oxygen │
│ 2. Vascular access (IO if IV not immediately available) │
│ 3. Check blood glucose │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ FLUID BOLUS │
│ • 10-20 mL/kg crystalloid (0.9% saline or balanced solution) │
│ • Give over 5-10 minutes (push-pull or pressure bag) │
│ • If suspected cardiogenic: 5-10 mL/kg over 10-20 min │
└─────────────────────────────────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────────────────────────────────┐
│ REASSESS (HR, perfusion, mental status, BP, urine output) │
└─────────────────────────────────────────────────────────────────────────────┘
↓ ↓
STILL SHOCKED IMPROVED
↓ ↓
┌─────────────────────────────┐ ┌─────────────────────────────────────────┐
│ REPEAT BOLUS │ │ Maintenance fluids │
│ • 10-20 mL/kg │ │ Ongoing monitoring │
│ • Up to 40-60 mL/kg in │ │ Identify and treat underlying cause │
│ first hour for sepsis │ └─────────────────────────────────────────┘
│ │
│ After 40 mL/kg if still │
│ shocked: │
│ • Start vasoactive drugs │
│ • Adrenaline or │
│ noradrenaline infusion │
│ • PICU referral │
└─────────────────────────────┘
Pitfalls & Pearls
Clinical Pearls:
- Give 5 rescue breaths FIRST - paediatric arrests are hypoxic; oxygenation is the priority
- IO access is faster and more reliable than peripheral IV in arrest - do not delay
- Bradycardia with poor perfusion = CPR - don't wait for pulseless arrest
- Two-thumb encircling technique generates superior coronary perfusion pressure [12]
- Shockable rhythms are rare but must not be missed - especially in adolescents and witnessed arrests
- Adrenaline dose is the SAME regardless of rhythm - 10 mcg/kg every 3-5 minutes
- Hyperoxia is harmful post-ROSC - titrate FiO₂ to achieve SpO₂ 94-98%
- "Children are not small adults" - physiology, dosing, and approach differ fundamentally
- Parents know their child - take parental concern seriously ("something's not right")
Pitfalls to Avoid:
- Forgetting 5 rescue breaths - critical for hypoxic arrests, ANZCOR emphasises this
- Using 30:2 ratio with 2 rescuers - should be 15:2 in paediatrics with 2 HCPs
- Pausing compressions during defibrillator charging - continue until shock delivery
- Delaying CPR to establish IV access - use IO immediately if IV not immediately available
- Inappropriate ETT size or depth - always calculate using formulas, confirm with ETCO₂
- Overcrowding the resuscitation - limit personnel to those with defined roles
- Not treating reversible causes - actively search and treat the 4Hs and 4Ts
- Hyperventilating - reduces venous return, causes gastric distension
- Not checking blood glucose in altered consciousness - hypoglycaemia is reversible
- Using adult doses - always calculate weight-based doses
- Not involving the family - family presence is a quality marker
- Forgetting mandatory reporting if NAI suspected
Viva Practice
Stem: You are called to resuscitation. A 6-month-old infant has been brought in by ambulance. The baby was found unresponsive in his cot this morning. Paramedics commenced CPR en route. The monitor shows asystole. There is no ROSC after 10 minutes of pre-hospital CPR.
Opening Question: How would you approach this situation as the resuscitation team leader?
Model Answer: This is a paediatric cardiac arrest in an infant with a non-shockable rhythm and prolonged down-time. I would take a systematic approach while remaining prepared for a difficult outcome.
-
Initial Actions:
- Confirm cardiac arrest (unresponsive, no breathing, no central pulse)
- Ensure high-quality CPR continues (15:2 ratio, two-thumb encircling technique)
- Confirm rhythm is asystole on monitor (check leads, gain)
- Estimate weight: approximately 7-8 kg at 6 months
-
Team Organisation:
- Assign clear roles: airway, compressions (rotate every 2 min), access/drugs, scribe/time
- Request paediatric resuscitation drugs and Broselow tape
- Ensure someone is documenting timing and interventions
-
Immediate Interventions:
- Confirm or obtain vascular access (IO if not already in place)
- Give adrenaline 70-80 mcg (10 mcg/kg) IV/IO immediately
- Continue CPR for 2 minutes, then reassess rhythm
- Repeat adrenaline every 3-5 minutes
-
Airway Management:
- Confirm effective BVM ventilation with visible chest rise
- Consider intubation if experienced operator (3.5 mm cuffed ETT, depth ~10 cm)
- Attach ETCO₂ monitor if intubated
-
Reversible Causes to Consider:
- Hypoxia - ensure oxygenation and ventilation adequate
- SIDS/SUDI - likely in this scenario (unexplained infant death)
- Sepsis - any history of illness?
- Non-accidental injury - document any injuries carefully
- Congenital heart disease - any known history?
-
Family Considerations:
- Assign staff member to support parents
- Offer family presence during resuscitation
- Prepare for likely need to cease resuscitation
Follow-up Questions:
-
After 20 minutes of optimal ALS with 4 doses of adrenaline, the rhythm remains asystole. ETCO₂ has been consistently below 10 mmHg. What factors influence your decision about continuing?
Model answer: The clinical picture suggests a non-survivable event. Key factors suggesting futility include: prolonged arrest with unknown down-time, persistently non-shockable rhythm despite optimal CPR, no response to adrenaline, ETCO₂ persistently below 10 mmHg (indicates inadequate cardiac output), and no ROSC after over 20 minutes. In this setting, I would discuss with the team about cessation and then with the family. However, this is a decision made with the team - not alone.
-
The parents want to be present. How do you manage this?
Model answer: I would strongly support parental presence. I would assign a dedicated, experienced staff member to stay with the parents. They would be positioned where they can see their baby and touch their hand or foot, but not obstruct the resuscitation. The support person would explain what is happening in plain language. I would include them in discussions about ongoing resuscitation and cessation. Their presence facilitates the grieving process.
-
The resuscitation is ceased. What happens next?
Model answer: This is a sudden unexpected death in infancy (SUDI) and will require coronial investigation. I would: allow parents extended time with their baby, remove non-essential equipment but leave IV access/ETT in situ, contact the Coroner/police as per local protocol, document everything carefully, offer cultural/religious support (chaplaincy), provide SIDS support service information, arrange bereavement follow-up. Photos and mementos should be offered.
Discussion Points:
- Infant compression technique (two-thumb encircling preferred)
- Non-shockable rhythm management
- ETCO₂ as prognostic indicator
- Family presence during resuscitation
- SUDI investigation requirements
Stem: A 10-year-old boy collapses on the school sports field during athletics training. Teachers commence CPR immediately and an AED delivers one shock before paramedics arrive. On arrival to ED, he remains in VF despite 3 shocks pre-hospital. CPR is ongoing.
Opening Question: What are your immediate priorities as the team leader?
Model Answer: This is a witnessed paediatric cardiac arrest with a shockable rhythm - this is the best-case scenario for paediatric arrest with early bystander CPR and defibrillation. I need to optimise all modifiable factors.
-
Confirm Situation:
- Verify VF on our monitor (not artefact)
- Confirm weight: approximately 30-35 kg for 10-year-old
- Ensure high-quality CPR continues (15:2, depth ~5 cm)
-
Immediate Defibrillation:
- Charge to 4 J/kg while compressions continue
- 4 J/kg × 30 kg = 120-140 J
- Deliver 4th shock with minimal pause
- Resume CPR immediately for 2 minutes
-
Medications (should already be given pre-hospital):
- Confirm adrenaline given after 2nd shock (300 mcg)
- Confirm amiodarone given after 3rd shock (150 mg = 5 mg/kg)
- Continue adrenaline every 3-5 minutes
- Second dose amiodarone 150 mg can be given after 5th shock
-
Reversible Causes - Sporting Collapse Differential:
- Channelopathies: Long QT syndrome, Brugada, CPVT
- Hypertrophic cardiomyopathy: Most common cause of SCD in young athletes
- Commotio cordis: If chest wall impact occurred
- ARVC: Arrhythmogenic right ventricular cardiomyopathy
- Anomalous coronary artery: Rare but important
- Electrolyte abnormality: Heat-related?
- Drug use: Stimulants, supplements?
-
Advanced Considerations:
- Secure airway if not already (6.0-6.5 mm cuffed ETT)
- Continuous ETCO₂ monitoring
- Consider double sequential defibrillation if continues refractory
- Early consideration of ECMO if available (ECPR)
Follow-up Questions:
-
After 6 shocks and 2 doses of amiodarone, VF persists. What are your options?
Model answer: This is refractory VF. Options include: ensure pads are positioned optimally (consider anterior-posterior if not already), consider double sequential external defibrillation if second defibrillator available, ensure all reversible causes addressed, continue high-quality CPR with minimal interruptions, consider ECMO referral if available (ECPR indication). Continue resuscitation - witnessed VF in a child with early CPR/defibrillation can still have good outcome.
-
He achieves ROSC after the 7th shock. What are your immediate post-ROSC priorities?
Model answer: Immediate priorities: 12-lead ECG (look for long QT, pre-excitation, Brugada pattern), optimise oxygenation to SpO₂ 94-98% (avoid hyperoxia), maintain normocapnia, haemodynamic support to maintain age-appropriate BP, prevent hyperthermia (TTM consideration), urgent paediatric cardiology referral, PICU admission, prepare family for uncertainty about neurological prognosis.
-
The 12-lead ECG post-ROSC shows QTc of 520ms. What is the significance?
Model answer: Prolonged QTc suggests Long QT syndrome, a channelopathy causing predisposition to polymorphic VT/torsades and VF. This explains the cardiac arrest. Management includes: avoid QT-prolonging medications, maintain normal K+ and Mg++, beta-blocker therapy once stable, genetic testing for specific LQT type, family screening (autosomal dominant), potential ICD consideration, restriction from competitive sports pending cardiology review.
Discussion Points:
- Causes of sudden cardiac death in young athletes
- Refractory VF management strategies
- ECPR indication in paediatrics
- Channelopathies and screening
Stem: A 2-year-old child is brought to the ED following a choking episode at home. She choked on a grape but parents performed back blows and it was expelled. However, she remained pale and floppy. On arrival: HR 45/min, SpO₂ 72% on room air, GCS 8, weak central pulses, CRT 5 seconds.
Opening Question: Is this child in cardiac arrest? What is your approach?
Model Answer: This is NOT a cardiac arrest - she has a pulse, albeit with bradycardia and poor perfusion. However, this is a pre-arrest state requiring immediate intervention. Bradycardia with poor perfusion in a child is an indication for CPR.
-
Recognition:
- Heart rate below 60/min with signs of poor perfusion = indication for CPR even with pulse
- This is likely hypoxic bradycardia secondary to the choking episode
- The hypoxia and bradycardia are causing poor perfusion
-
Immediate Actions (Simultaneous):
- High-flow oxygen immediately
- Open airway (head tilt-chin lift, check for obstruction)
- Assist ventilation with BVM if inadequate respiratory effort
- If HR remains below 60 despite oxygenation → START CPR
-
Weight-Based Preparation:
- 2-year-old: approximately 12 kg
- Adrenaline: 120 mcg (1.2 mL of 1:10,000) IV/IO
- ETT if needed: 4.0-4.5 mm cuffed, depth 12 cm
-
Vascular Access and Drugs:
- Obtain IO access immediately if no IV
- If HR remains below 60 with poor perfusion after oxygenation:
- Give adrenaline 120 mcg IV/IO
- Continue CPR
-
If Responds to Oxygenation:
- HR should increase rapidly if hypoxia was the sole cause
- Monitor closely
- CXR if concern for aspiration
Follow-up Questions:
-
With high-flow oxygen and BVM ventilation, her HR increases to 120/min and SpO₂ rises to 98%. She begins to rouse. What now?
Model answer: This confirms hypoxic bradycardia with resolution following oxygenation. I would: continue supplemental oxygen, maintain continuous monitoring, keep resuscitation team ready, perform full examination for any injuries, CXR to exclude aspiration or foreign body, observe for at least 4-6 hours, consider admission for observation, provide choking prevention education to parents.
-
Despite BVM ventilation, her HR remains 40/min and she deteriorates to cardiac arrest. What has changed?
Model answer: This is now a pulseless cardiac arrest. The aetiology is likely hypoxic arrest secondary to the choking episode - there may be residual airway obstruction, aspiration, or neurological injury from prolonged hypoxia. I would: confirm pulseless, start full PALS algorithm with 5 rescue breaths then CPR, give adrenaline 120 mcg immediately (non-shockable rhythm expected), perform laryngoscopy to visualise and clear any residual foreign body, continue aggressive airway management.
-
What is the most likely cause of the bradycardia in this case?
Model answer: Hypoxia from the choking episode. Bradycardia in children is almost always secondary to hypoxia, not a primary cardiac problem. The prolonged hypoxia from the foreign body obstruction led to bradycardia, which then caused poor perfusion. Treating the underlying cause (restoring oxygenation) is the priority. Drugs are secondary to establishing adequate oxygenation and ventilation.
Discussion Points:
- Bradycardia with poor perfusion = indication for CPR
- Hypoxic bradycardia as primary mechanism in paediatrics
- Foreign body airway obstruction complications
- Post-choking observation and education
OSCE Scenarios
Station 1: Paediatric Resuscitation Team Leadership
Format: Resuscitation Leadership (Manikin-based simulation) Time: 11 minutes Setting: ED Resuscitation Bay
Candidate Instructions:
You are the senior registrar in a metropolitan ED. A 3-year-old child (approximately 15 kg based on Broselow tape) has been brought in by ambulance following witnessed seizure activity at home that progressed to respiratory arrest. Paramedics commenced BVM ventilation but report the child became bradycardic then pulseless 2 minutes ago. CPR is in progress. Lead the resuscitation.
Examiner Instructions:
- Manikin with monitor showing asystole
- Weight confirmed as 15 kg by Broselow tape
- If candidate follows algorithm correctly, rhythm changes to VF at 6 minutes
- If candidate provides high-quality CPR with adrenaline and defibrillation for VF, ROSC occurs at 9 minutes
- If candidate fails to recognise VF or delays defibrillation, rhythm deteriorates to asystole
Team Available:
- Nurse 1: Experienced, can assist with airway and drugs
- Nurse 2: Junior, needs clear direction
- Resident: Available to assist
Resources Available:
- Full paediatric resuscitation equipment
- Broselow tape (already measured - 15 kg)
- Defibrillator with paediatric pads
- IO drill
- Paediatric resuscitation drugs
Marking Criteria:
| Domain | Criterion | Marks |
|---|---|---|
| Initial Assessment | Confirms pulseless arrest, assigns roles, confirms weight | /1 |
| CPR Quality | Ensures correct technique (15:2, depth 5 cm, two-thumb technique) | /2 |
| Algorithm Adherence | Follows ANZCOR paediatric ALS algorithm correctly | /2 |
| Drug Dosing | Correct weight-based adrenaline (150 mcg) and amiodarone (75 mg) | /2 |
| Rhythm Recognition | Recognises change to VF, initiates defibrillation correctly (60 J) | /1 |
| Reversible Causes | Systematically considers 4Hs/4Ts including seizure-related causes | /1 |
| Communication | Closed-loop communication, verbalises findings and decisions | /1 |
| Post-ROSC Management | If ROSC achieved, initiates appropriate care | /1 |
| Total | /11 |
Expected Standard:
- Pass: ≥6/11
- Key discriminators: Correct CPR ratio (15:2), correct drug doses, recognition of VF, appropriate defibrillation
Station 2: Breaking Bad News - Paediatric Death
Format: Communication Station Time: 11 minutes Setting: Relatives Room
Candidate Instructions:
You are the registrar in the ED. A 9-month-old infant was brought in by ambulance following a SUDI (Sudden Unexpected Death in Infancy). Despite 30 minutes of resuscitation, the infant did not survive. The parents are waiting in the relatives' room. Break the news of their child's death.
Actor Brief (Mother):
- 28 years old, first baby
- Found baby unresponsive in cot this morning
- Healthy pregnancy and birth, no medical problems
- Extremely distressed, tearful
- Father is silent, appears in shock
- Will ask: "Is he going to be okay?" and "Did I do something wrong?"
Expected Actions:
- Introduce self, confirm identities, sit down
- Establish what they know so far
- Use a "warning shot" to prepare them ("I have some very difficult news...")
- Deliver news clearly and compassionately using plain language
- Allow silence and expression of emotion
- Answer questions honestly
- Address guilt (extremely common with SUDI - "This is not your fault")
- Explain next steps sensitively (viewing baby, police involvement, coronial process)
- Offer support services (chaplaincy, social work, SIDS support)
Marking Criteria:
| Domain | Criterion | Marks |
|---|---|---|
| Setting | Appropriate environment, sits down, maintains privacy | /1 |
| Introduction | Confirms identities, establishes what they know | /1 |
| Warning Shot | Prepares them for bad news | /1 |
| Delivery | Clear, compassionate, no medical jargon | /2 |
| Silence | Allows time for emotion, does not rush or fill silence | /1 |
| Empathy | Acknowledges feelings, uses supportive statements | /2 |
| Information | Explains SUDI, coronial process, next steps sensitively | /1 |
| Support | Offers chaplaincy, social work, SIDS support services | /1 |
| Closure | Asks if questions, offers to return, provides ongoing support | /1 |
| Total | /11 |
Expected Standard:
- Pass: ≥6/11
- Key discriminators: Ability to deliver news clearly, demonstrate genuine empathy, address parental guilt, awareness of coronial process
Station 3: Paediatric Defibrillation Demonstration
Format: Procedural Skills Station Time: 8 minutes Setting: Simulation Laboratory
Candidate Instructions:
You are managing a 5-year-old child (20 kg) in cardiac arrest. The rhythm on the monitor is ventricular fibrillation. Demonstrate the process of delivering a defibrillation shock. Talk through your actions as you perform them on the manikin.
Equipment Available:
- Defibrillator with paediatric and adult pads
- Paediatric manikin (5-year-old size)
- Gel pads
Expected Actions:
- Confirm VF on monitor (not artefact)
- Announce weight and calculate energy: "This is a 20 kg child, energy is 4 J/kg = 80 J"
- Select appropriate pads (paediatric if available, adult acceptable)
- Apply pads correctly (anterior-posterior or sternal-apex, ensuring no overlap)
- State "Continue CPR while I charge the defibrillator"
- Set energy to 80 J
- Charge while compressions continue
- Perform safety check: "I'm clear, you're clear, everyone's clear" with visual sweep
- State "Delivering shock now"
- Deliver shock with minimal pause
- State "Resume CPR immediately, do not check rhythm"
- Articulate drug timing: "After this 2-minute cycle, we will give adrenaline. Amiodarone after the 3rd shock."
Marking Criteria:
| Domain | Criterion | Marks |
|---|---|---|
| Rhythm Recognition | Correctly identifies VF | /1 |
| Energy Calculation | Correct calculation: 4 J/kg × 20 kg = 80 J | /2 |
| Pad Selection | Appropriate pads, correct placement | /1 |
| CPR Continuation | Continues compressions during charging | /2 |
| Safety Check | Verbalises and performs safety check | /2 |
| Post-Shock Actions | Resumes CPR immediately, articulates drug timing | /2 |
| Total | /10 |
SAQ Practice
Question 1 (6 marks)
Stem: A 4-year-old child (16 kg) is brought to the emergency department in cardiac arrest following drowning in a backyard pool. CPR is in progress with an asystole rhythm on the monitor.
Question: List 6 key features of high-quality CPR in paediatric resuscitation according to ANZCOR guidelines.
Model Answer:
- Compression rate of 100-120 compressions per minute (1 mark)
- Compression depth of 1/3 of anterior-posterior chest diameter (~5 cm) (1 mark)
- Full chest recoil between compressions (1 mark)
- Minimise interruptions to below 10 seconds for rhythm checks (1 mark)
- Compression-to-ventilation ratio of 15:2 with two healthcare providers (1 mark)
- Rotate compressors every 2 minutes to prevent fatigue (1 mark)
Examiner Notes:
- Accept: Avoid excessive ventilation, ensure visible chest rise with ventilations
- Do NOT accept: 30:2 ratio (this is for single rescuers or lay rescuers, not two HCPs)
Question 2 (8 marks)
Stem: You are resuscitating a 2-year-old child (12 kg) who is in ventricular fibrillation. Three defibrillation shocks have been delivered without success.
Question (a): What medications should be given at this point, with correct doses for a 12 kg child? (4 marks)
Model Answer:
- Adrenaline 120 mcg (10 mcg/kg) IV/IO - should have been given after 2nd shock, continue every 3-5 min (2 marks)
- Amiodarone 60 mg (5 mg/kg) IV/IO - given after 3rd shock (2 marks)
Question (b): List 4 reversible causes you would actively consider in a child with refractory VF. (4 marks)
Model Answer (any 4 for full marks):
- Hypokalaemia or hyperkalaemia (1 mark)
- Hypothermia (1 mark)
- Toxins (including sodium channel blockers, tricyclic antidepressants, local anaesthetics) (1 mark)
- Channelopathies/primary cardiac cause (Long QT, Brugada, WPW) (1 mark)
- Hypertrophic cardiomyopathy (1 mark)
- Commotio cordis (if history of chest impact) (1 mark)
Question 3 (8 marks)
Stem: A 6-month-old infant (7 kg) has a witnessed cardiac arrest in the ED. You are the team leader.
Question (a): Describe the correct compression technique for infant CPR with two healthcare providers. (4 marks)
Model Answer:
- Two-thumb encircling technique is preferred (1 mark)
- Both thumbs placed side-by-side on lower third of sternum, just below nipple line (1 mark)
- Fingers encircle chest to support the back (1 mark)
- Compress to 1/3 of anterior-posterior diameter (~4 cm) at rate of 100-120/min (1 mark)
Question (b): Calculate the correct doses and sizes for this 7 kg infant: (4 marks)
| Parameter | Answer |
|---|---|
| Adrenaline IV/IO | 70 mcg (0.7 mL of 1:10,000) (1 mark) |
| Amiodarone IV/IO | 35 mg (1 mark) |
| Defibrillation energy | 28 J (4 J/kg × 7 kg) (1 mark) |
| Cuffed ETT size | 3.5 mm (Age/4 + 3.5 = 0/4 + 3.5 = 3.5) (1 mark) |
Question 4 (6 marks)
Stem: Following successful resuscitation of an 8-year-old child (25 kg) from cardiac arrest, you are managing the post-resuscitation phase in the ED before PICU transfer.
Question: List 6 key targets or interventions for immediate post-resuscitation care.
Model Answer (any 6 for full marks):
- Maintain SpO₂ 94-98% - avoid hyperoxia (1 mark)
- Maintain normocapnia - PaCO₂ 35-45 mmHg (1 mark)
- Maintain age-appropriate blood pressure (MAP ≥5th centile for age) (1 mark)
- Maintain glucose 6-10 mmol/L - avoid hypo/hyperglycaemia (1 mark)
- Prevent fever - temperature below 37.5°C, or targeted temperature management 32-34°C (1 mark)
- 12-lead ECG to identify cause (channelopathy, ischaemia) (1 mark)
- Treat seizures aggressively if present (1 mark)
- Secure airway if not already intubated (1 mark)
Question 5 (6 marks)
Stem: A 3-year-old child (15 kg) presents with SVT at a rate of 260/min. She is pale and lethargic with capillary refill time of 4 seconds but remains conscious.
Question (a): What is your first-line treatment for this haemodynamically compromised but conscious child? (2 marks)
Model Answer:
- Vagal manoeuvres as first-line (1 mark)
- Specifically: ice pack to face for 5-10 seconds (covers nose and mouth briefly) OR modified Valsalva in cooperative older children (1 mark)
Question (b): If vagal manoeuvres fail, describe the pharmacological treatment with doses for a 15 kg child. (4 marks)
Model Answer:
- Adenosine is first-line pharmacological treatment (1 mark)
- Escalating dose regimen:
- 1st dose: 1.5 mg (100 mcg/kg × 15 kg) - max 6 mg (1 mark)
- 2nd dose: 3 mg (200 mcg/kg × 15 kg) - max 12 mg (1 mark)
- 3rd dose: 4.5 mg (300 mcg/kg × 15 kg) - max 12 mg (1 mark)
- Technique: Rapid IV push via proximal access with immediate 10-20 mL saline flush
Remote/Rural Considerations
Challenges in Remote/Rural Paediatric Resuscitation
- Prolonged EMS response times - may be hours in remote Australia
- Limited paediatric expertise - may be sole practitioner
- Limited equipment - may not have all paediatric sizes
- Retrieval delays - RFDS/helicopter availability
- Telemedicine - variable connectivity
Strategies
| Challenge | Strategy |
|---|---|
| Delayed EMS | Community first responder programs, bystander CPR training |
| Limited expertise | Telemedicine consultation with paediatric specialists, standardised protocols |
| Limited equipment | Broselow tape, length-based equipment, improvisation |
| Prolonged transport | Prepare for ongoing resuscitation during transport, mechanical CPR devices |
| Communication | Early activation of retrieval services, pre-prepared handover |
Royal Flying Doctor Service (RFDS) / Retrieval Coordination
- Activate early - call retrieval for ANY paediatric cardiac arrest
- Prepare landing - airstrip/helipad ready
- Prepare handover - weight, medications given, arrest duration, suspected cause
- Prepare family - will need to travel separately in most cases
Australian Guidelines Summary
Key ANZCOR Guidelines for PALS
| Guideline | Title | Key Content |
|---|---|---|
| Guideline 6 | Compressions | Technique, rate, depth, ratio |
| Guideline 10 | Basic Life Support - Infants and Children | Paediatric BLS algorithm |
| Guideline 12 | Paediatric Advanced Life Support | Full PALS algorithm |
| Guideline 12.1 | Paediatric Defibrillation | 4 J/kg, pad selection |
| Guideline 12.2 | Paediatric Airway Management | Sizing, technique |
| Guideline 12.6 | Drugs in Paediatric Resuscitation | Dosing, timing |
| Guideline 13 | Neonatal Life Support | below 28 days - separate algorithm |
Key Differences from AHA/ERC
| Element | ANZCOR | AHA | ERC |
|---|---|---|---|
| Initial rescue breaths | 5 breaths emphasised | C-A-B (compressions first) | 5 breaths |
| Defibrillation energy | 4 J/kg ALL shocks | 2 J/kg first, then 4 J/kg | 4 J/kg |
| Compression ratio (2 HCP) | 15:2 | 15:2 | 15:2 |
| Sequence emphasis | Ventilation priority | Compression priority | Ventilation priority |
References
Guidelines
-
Australian Resuscitation Council. ANZCOR Guideline 12: Paediatric Advanced Life Support. 2021. Available from: https://resus.org.au/guidelines/
-
Australian Resuscitation Council. ANZCOR Guideline 10: Basic Life Support for Infants and Children. 2021. Available from: https://resus.org.au/guidelines/
-
Holmberg MJ, Ross CE, Fitzmaurice GM, et al. Annual Incidence of Adult and Pediatric In-Hospital Cardiac Arrest. Circ Cardiovasc Qual Outcomes. 2019;12(7):e005580. PMID: 31545574
-
Girotra S, Spertus JA, Li Y, et al. Survival Trends in Pediatric In-Hospital Cardiac Arrests. Circ Cardiovasc Qual Outcomes. 2013;6(1):42-49. PMID: 23250980
-
Atkins DL, Everson-Stewart S, Sears GK, et al. Epidemiology and Outcomes From Out-of-Hospital Cardiac Arrest in Children. Circulation. 2009;119(11):1484-1491. PMID: 19273724
-
Berg RA, Nadkarni VM, Clark AE, et al. Incidence and Outcomes of Cardiopulmonary Resuscitation in PICUs. Crit Care Med. 2016;44(4):798-808. PMID: 26646453
-
Topjian AA, Raymond TT, Atkins D, et al. Part 4: Pediatric Basic and Advanced Life Support: 2020 American Heart Association Guidelines. Circulation. 2020;142(16_suppl_2):S469-S523. PMID: 33081526
-
Meyer L, Stubbs B, Fahrenbruch C, et al. Incidence, causes, and survival trends from cardiovascular-related sudden cardiac arrest in children and young adults. Circulation. 2012;126(11):1363-1372. PMID: 22887927
-
Donoghue AJ, Nadkarni V, Berg RA, et al. Out-of-hospital pediatric cardiac arrest: an epidemiologic review. Ann Emerg Med. 2005;46(6):512-522. PMID: 16308066
-
Deasy C, Bernard SA, Cameron P, et al. Epidemiology of paediatric out-of-hospital cardiac arrest in Melbourne, Australia. Resuscitation. 2010;81(9):1095-1100. PMID: 20541854
-
O'Grady KF, Hall KK, Sloots TP, et al. Upper airway viruses and bacteria in urban Aboriginal and Torres Strait Islander children in Brisbane, Australia. BMC Infect Dis. 2017;17(1):245. PMID: 28381224
-
Sutton RM, Niles D, Nysaether J, et al. Quantitative analysis of CPR quality during in-hospital resuscitation of older children and adolescents. Pediatrics. 2009;124(2):494-499. PMID: 19581265
-
Moler FW, Silverstein FS, Holubkov R, et al. Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children. N Engl J Med. 2017;376(4):318-329. PMID: 28118559
-
Moler FW, Silverstein FS, Holubkov R, et al. Therapeutic Hypothermia after Out-of-Hospital Cardiac Arrest in Children. N Engl J Med. 2015;372(20):1898-1908. PMID: 25913022
-
Jabre P, Belpomme V, Azoulay E, et al. Family presence during cardiopulmonary resuscitation. N Engl J Med. 2013;368(11):1008-1018. PMID: 23484827
-
Lasa JJ, Rogers RS, Localio R, et al. Extracorporeal Cardiopulmonary Resuscitation (E-CPR) During Pediatric In-Hospital Cardiopulmonary Arrest Is Associated With Improved Survival to Discharge. Circulation. 2016;133(2):165-176. PMID: 26635401
-
Maconochie IK, Aickin R, Hazinski MF, et al. Pediatric Life Support: 2020 International Consensus on Cardiopulmonary Resuscitation. Resuscitation. 2020;156:A120-A155. PMID: 33098920
-
Van de Voorde P, Turner NM, Djakow J, et al. European Resuscitation Council Guidelines 2021: Paediatric Life Support. Resuscitation. 2021;161:327-387. PMID: 33773830
-
Andersen LW, Berg KM, Saindon BZ, et al. Time to Epinephrine and Survival After Pediatric In-Hospital Cardiac Arrest. JAMA. 2015;314(8):802-810. PMID: 26305650
-
Valdes SO, Donoghue AJ, Hoyme DB, et al. Outcomes associated with amiodarone and lidocaine in the treatment of in-hospital pediatric cardiac arrest. Resuscitation. 2014;85(3):381-386. PMID: 24263336
-
Reades R, Studnek JR, Vandeventer S, Garrett J. Intraosseous versus intravenous vascular access during out-of-hospital cardiac arrest. Ann Emerg Med. 2011;58(6):509-516. PMID: 21856044
-
Santos D, Carron PN, Yersin B, Pasquier M. EZ-IO intraosseous device implementation in a pre-hospital emergency service. Resuscitation. 2013;84(4):440-445. PMID: 23069592
-
Weiss M, Dullenkopf A, Fischer JE, et al. Prospective randomized controlled multi-centre trial of cuffed or uncuffed endotracheal tubes in small children. Br J Anaesth. 2009;103(6):867-873. PMID: 19887533
-
Berg RA, Sutton RM, Reeder RW, et al. Association between diastolic blood pressure during pediatric in-hospital CPR and survival. Circulation. 2018;137(17):1784-1795. PMID: 29459362
-
Sutton RM, Case E, Brown SP, et al. A quantitative analysis of out-of-hospital pediatric and adolescent resuscitation quality. Resuscitation. 2015;93:150-157. PMID: 25917262
-
Davis AL, Carcillo JA, Aneja RK, et al. American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock. Crit Care Med. 2017;45(6):1061-1093. PMID: 28509730
-
Weiss SL, Peters MJ, Alhazzani W, et al. Surviving Sepsis Campaign International Guidelines for Children. Pediatr Crit Care Med. 2020;21(2):e52-e106. PMID: 32032273
-
Brugada J, Blom N, Sarquella-Brugada G, et al. Pharmacological and non-pharmacological therapy for arrhythmias in the pediatric population. Europace. 2013;15(9):1337-1382. PMID: 23851511
-
Dalziel SR, Borland ML, Furyk J, et al. Levetiracetam versus phenytoin for convulsive status epilepticus in children (ConSEPT). Lancet. 2019;393(10186):2135-2145. PMID: 31005386
-
Szpilman D, Bierens JJ, Handley AJ, Orlowski JP. Drowning. N Engl J Med. 2012;366(22):2102-2110. PMID: 22646632
-
Scholefield BR, Silverstein FS, Telford R, et al. Therapeutic Hypothermia After Pediatric Cardiac Arrest: Pooled Randomized Controlled Trials. Resuscitation. 2018;133:101-107. PMID: 30300656
-
Kirschen MP, Topjian AA, Hammond R, et al. Neuroprognostication after pediatric cardiac arrest. Pediatr Crit Care Med. 2019;20(10):e457-e470. PMID: 31274696
-
McAlvin SS, Carew-Lyons A. Family presence during resuscitation and invasive procedures in pediatric critical care. Am J Crit Care. 2014;23(6):477-484. PMID: 25362671
-
Hunt EA, Vera K, Diener-West M, et al. Delays and errors in cardiopulmonary resuscitation by pediatric residents during simulated arrests. Resuscitation. 2009;80(7):819-825. PMID: 19423209
-
Shipstone RA, Young J, Kearney L. New approaches to prevent SUDI in high-risk Aboriginal and Torres Strait Islander families. J Paediatr Child Health. 2017;53(1):31-35. PMID: 27699930
-
Young KD, Korotzer NC. Weight estimation methods in children: a systematic review. Ann Emerg Med. 2016;68(4):441-451. PMID: 27105839
-
Gausche M, Lewis RJ, Stratton SJ, et al. Effect of out-of-hospital pediatric endotracheal intubation on survival and neurological outcome. JAMA. 2000;283(6):783-790. PMID: 10683058
-
Tijssen JA, Prince DK, Morrison LJ, et al. Time on the scene and interventions are associated with improved survival in pediatric OHCA. Resuscitation. 2015;94:1-7. PMID: 26095302
-
Nadkarni VM, Larkin GL, Peberdy MA, et al. First documented rhythm and clinical outcome from in-hospital cardiac arrest among children and adults. JAMA. 2006;295(1):50-57. PMID: 16391216
-
Meaney PA, Nadkarni VM, Cook EF, et al. Higher survival rates among younger patients after pediatric intensive care unit cardiac arrests. Pediatrics. 2006;118(6):2424-2433. PMID: 17142528
-
Quan L, Bierens JJ, Lis R, et al. Predicting outcome of drowning at the scene: a systematic review and meta-analyses. Resuscitation. 2016;104:63-75. PMID: 27164416
-
Thiagarajan RR, Barbaro RP, Rycus PT, et al. Extracorporeal Life Support Organization Registry International Report 2016. ASAIO J. 2017;63(1):60-67. PMID: 27984321
Frequently asked questions
Quick clarifications for common clinical and exam-facing questions.
What is the compression-to-ventilation ratio for paediatric CPR with two healthcare providers?
15:2 for two healthcare providers; 30:2 for single rescuer (same as adults)
What is the initial defibrillation energy for paediatric VF/pVT?
4 J/kg for all shocks according to ANZCOR guidelines
What is the adrenaline dose in paediatric cardiac arrest?
10 mcg/kg (0.01 mg/kg) IV/IO every 3-5 minutes
Should you give 5 rescue breaths before starting compressions in children?
Yes, ANZCOR recommends 5 initial rescue breaths as paediatric arrests are usually hypoxic
Learning map
Use these linked topics to study the concept in sequence and compare related presentations.
Prerequisites
Start here if you need the foundation before this topic.
- Paediatric Basic Life Support
- Paediatric Airway Management
Differentials
Competing diagnoses and look-alikes to compare.
Consequences
Complications and downstream problems to keep in mind.
- Hypoxic-Ischaemic Encephalopathy
- Post-Cardiac Arrest Syndrome