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EMERGENCY

Borderline Personality Disorder (EUPD)

High EvidenceUpdated: 2025-12-22

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Red Flags

  • High suicide and self-harm risk (impulsive)
  • Repeated ED presentations
  • Active suicidal ideation
Overview

Borderline Personality Disorder (EUPD)

1. Clinical Overview

Summary

Borderline Personality Disorder (BPD), also known as Emotionally Unstable Personality Disorder (EUPD), is characterised by a pervasive pattern of instability in interpersonal relationships, self-image, affects, and marked impulsivity beginning in early adulthood. Core features include fear of abandonment, unstable relationships (often with "splitting" between idealisation and devaluation), identity disturbance, impulsive behaviours, recurrent self-harm or suicidal behaviour, affective instability, chronic emptiness, intense anger, and transient paranoid ideation. BPD is strongly associated with childhood trauma and invalidating environments. Treatment is primarily psychological, with Dialectical Behaviour Therapy (DBT) as the gold standard. Medications have a limited role.

Key Facts

  • Core Features: Fear of abandonment, Unstable relationships, Identity disturbance, Impulsivity, Self-harm, Affective instability, Emptiness, Anger, Paranoid ideation
  • Mnemonic: IMPULSIVE
  • Prevalence: 1-2% of population; F:M = 3:1
  • Association: Childhood trauma, invalidation
  • Treatment: DBT is gold standard; MBT also effective
  • Medication: Limited role; avoid polypharmacy

Clinical Pearls

"IMPULSIVE" Mnemonic: Impulsive, Moodiness, Paranoia, Unstable self-image, Labile, Suicidal, Inappropriate anger, Vulnerability to abandonment, Emptiness.

"Splitting is the Defence": Patients often view people as all good or all bad. This can affect therapeutic relationships. Maintain consistent boundaries.

"DBT, Not Drugs": Medications have limited evidence. DBT (skills training + individual therapy) is the most effective treatment.

"Admission Often Worsens": Psychiatric admission can foster regression and dependency. Crisis management should focus on outpatient support where safe.


2. Epidemiology

Prevalence

  • 1-2% of general population
  • 10-20% of psychiatric outpatients
  • 20-40% of psychiatric inpatients

Demographics

  • F:M = 3:1 (historically; may be ascertainment bias)
  • Onset: Early adulthood (symptoms may appear in adolescence)
  • Course: Tends to improve with age (50% no longer meet criteria by 40s)

Associated Factors

FactorNotes
Childhood traumaSexual/physical abuse, neglect
Invalidating environmentEmotions dismissed or punished
Genetic predispositionHeritable component
Attachment problemsDisorganised attachment

3. Pathophysiology

Biosocial Model (Linehan)

  • Biological: Emotional vulnerability (high reactivity, slow return to baseline)
  • Social: Invalidating environment (emotions dismissed, punished)
  • Result: Failure to learn emotion regulation skills

Neurobiological Findings

  • Amygdala hyperactivity
  • Prefrontal cortex hypofunction
  • HPA axis dysregulation
  • Serotonergic dysfunction

4. Clinical Presentation

DSM-5 Criteria (5 or more of 9)

CriterionDescription
1Frantic efforts to avoid real or imagined abandonment
2Pattern of unstable, intense relationships (idealisation/devaluation)
3Identity disturbance (unstable self-image)
4Impulsivity in ≥2 damaging areas (spending, sex, substances, binge eating, reckless driving)
5Recurrent suicidal behaviour, gestures, threats, or self-harm
6Affective instability (mood reactivity)
7Chronic feelings of emptiness
8Inappropriate, intense anger or difficulty controlling anger
9Transient, stress-related paranoid ideation or severe dissociation

Presentation Patterns


Repeated ED presentations (self-harm, overdose)
Common presentation.
Chaotic relationships with staff (splitting)
Common presentation.
Impulsive behaviours
Common presentation.
History of trauma
Common presentation.
5. Clinical Examination

Mental State Examination

DomainPossible Findings
AppearanceSelf-harm scars, variable dress
BehaviourMay be distressed, angry, or calm
MoodLabile; often low or anxious
AffectRapidly changing; intensely reactive
Thought contentSuicidal ideation, paranoid ideas
PerceptionMay report dissociation; rarely hallucinations
CognitionUsually intact
InsightVariable

Risk Assessment

  • Always assess suicide and self-harm risk
  • Ask about means, plans, intent
  • Consider impulsivity (increases unpredictability)

6. Investigations

Clinical Diagnosis

  • No blood tests or imaging
  • Careful clinical interview
  • Structured assessment tools (e.g., SCID-II)

Rule Out

  • Bipolar disorder (mood episodes, not reactive)
  • Complex PTSD (consider overlap)
  • Other personality disorders

7. Management

Treatment Approach

┌──────────────────────────────────────────────────────────┐
│   BPD/EUPD MANAGEMENT                                    │
├──────────────────────────────────────────────────────────┤
│                                                          │
│  PSYCHOLOGICAL THERAPY (Mainstay):                        │
│                                                          │
│  • DBT (Dialectical Behaviour Therapy) - GOLD STANDARD   │
│    - Individual therapy + skills group                   │
│    - Targets emotional dysregulation                     │
│    - Skills: Mindfulness, Distress tolerance, Emotion    │
│      regulation, Interpersonal effectiveness             │
│                                                          │
│  • MBT (Mentalisation-Based Therapy)                     │
│    - Focus on understanding own and others' mental states│
│                                                          │
│  • Schema-Focused Therapy                                │
│    - Addresses core schemas from early experiences       │
│                                                          │
│  CRISIS MANAGEMENT:                                       │
│  • Develop crisis plan with patient                      │
│  • Identify triggers and coping strategies               │
│  • Avoid admission unless life-threatening risk          │
│  • Brief ED contact; avoid reinforcing presentations     │
│  • Signpost to crisis teams                              │
│                                                          │
│  MEDICATION (Limited role):                               │
│  • No medications licensed for BPD                       │
│  • May use short-term for comorbidities:                 │
│    - SSRIs (depression, anxiety)                         │
│    - Low-dose antipsychotics (paranoia, impulsivity)     │
│    - Mood stabilisers (affective instability)            │
│  ⚠️ AVOID POLYPHARMACY                                   │
│  ⚠️ AVOID BENZODIAZEPINES (dependence, disinhibition)    │
│                                                          │
└──────────────────────────────────────────────────────────┘

Managing the Therapeutic Relationship

  • Maintain consistent boundaries
  • Expect splitting and prepare team
  • Regular supervision for staff
  • Validate emotions while not reinforcing harmful behaviours

8. Complications

Of BPD

  • Completed suicide (8-10% lifetime)
  • Repeated self-harm
  • Substance misuse
  • Eating disorders
  • Relationship breakdown
  • Unemployment
  • Comorbid depression, anxiety, PTSD

Of Treatment

  • Therapeutic ruptures
  • Dependency on services
  • Medication side effects (if inappropriately prescribed)

9. Prognosis & Outcomes

Natural History

  • Symptoms often improve with age
  • 50% no longer meet criteria by 40s-50s
  • Self-harm and impulsivity tend to reduce

With Treatment

  • DBT reduces self-harm by 50%
  • Improved functioning and quality of life

Mortality

  • Suicide rate: 8-10% (higher than general population)
  • Risk highest in younger patients and those with comorbid depression

10. Evidence & Guidelines

Key Guidelines

  1. NICE CG78: Borderline Personality Disorder
  2. APA Practice Guideline: Borderline Personality Disorder

Key Evidence

DBT

  • RCTs show reduced self-harm, ED presentations, hospitalisations

MBT

  • Also effective; may be better for attachment-related symptoms

11. Patient/Layperson Explanation

What is Borderline Personality Disorder?

BPD (sometimes called Emotionally Unstable Personality Disorder or EUPD) is a mental health condition where you experience very intense emotions that are hard to manage. It can feel like you're on an emotional rollercoaster.

What Are the Main Features?

  • Fear of being abandoned by people you're close to
  • Intense relationships that can swing between love and hate
  • Not being sure who you are
  • Acting impulsively (spending, risky behaviour)
  • Thoughts of hurting yourself or suicide
  • Mood swings
  • Feeling empty inside
  • Anger that's hard to control
  • Sometimes feeling paranoid or disconnected from reality

What Causes It?

Usually a combination of:

  • Difficult experiences in childhood (trauma, neglect)
  • Being in an environment where your emotions weren't taken seriously
  • Biological factors (how your brain processes emotions)

How is it Treated?

The main treatment is talking therapy, especially:

  • DBT (Dialectical Behaviour Therapy): Teaches skills to manage emotions
  • MBT (Mentalisation-Based Therapy): Helps you understand your own and others' feelings

Medications can help with some symptoms (like depression) but are not the main treatment.

Can You Recover?

Yes. Many people with BPD see significant improvement over time, especially with the right therapy. It's possible to have a fulfilling life and relationships.


12. References

Primary Guidelines

  1. NICE. Borderline Personality Disorder: Recognition and Management (CG78). 2009, updated 2018. nice.org.uk/guidance/cg78

Key Studies

  1. Linehan MM, et al. Dialectical behavior therapy for high suicide risk in individuals with borderline personality disorder. JAMA Psychiatry. 2006;63(7):757-766. PMID: 16818865

Last updated: 2025-12-22

At a Glance

EvidenceHigh
Last Updated2025-12-22
Emergency Protocol

Red Flags

  • High suicide and self-harm risk (impulsive)
  • Repeated ED presentations
  • Active suicidal ideation

Clinical Pearls

  • **"IMPULSIVE" Mnemonic**: **I**mpulsive, **M**oodiness, **P**aranoia, **U**nstable self-image, **L**abile, **S**uicidal, **I**nappropriate anger, **V**ulnerability to abandonment, **E**mptiness.
  • **"Splitting is the Defence"**: Patients often view people as all good or all bad. This can affect therapeutic relationships. Maintain consistent boundaries.
  • **"DBT, Not Drugs"**: Medications have limited evidence. DBT (skills training + individual therapy) is the most effective treatment.
  • **"Admission Often Worsens"**: Psychiatric admission can foster regression and dependency. Crisis management should focus on outpatient support where safe.

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines