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Obstetrics
Anaesthesia

Caesarean Section

High EvidenceUpdated: 2025-12-24

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Red Flags

  • Category 1 CS (immediate threat to life of mother or baby)
  • Placenta accreta spectrum (increasing risk with multiple prior CS)
  • Uterine rupture (especially VBAC)
  • Massive obstetric haemorrhage
  • Cord prolapse
  • Uterine hyperstimulation with fetal distress
Overview

Caesarean Section

1. Clinical Overview

Summary

Caesarean section (CS) is the surgical delivery of a baby through incisions in the abdominal wall and uterus. It is one of the most commonly performed major surgical procedures worldwide, accounting for approximately 25-35% of all deliveries in developed countries. The lower segment caesarean section (LSCS) is the standard technique, involving a transverse incision in the lower uterine segment. Indications are classified as elective (planned) or emergency, and emergency cases are further categorised by urgency (Categories 1-4). While CS is a life-saving procedure, it carries maternal risks (haemorrhage, infection, thromboembolism) and has implications for future pregnancies (placenta accreta spectrum, uterine rupture).

Key Facts

  • CS rate: UK ~27%; varies globally from 5% to >50%
  • Category classification: 1 (immediate threat to life) to 4 (elective)
  • Category 1 target: Decision-to-delivery interval <30 minutes
  • Standard incision: Pfannenstiel (skin) + transverse lower segment (uterus)
  • Anaesthesia: Spinal (preferred) > Epidural > General (for Cat 1/emergencies)
  • Maternal mortality: Very rare (~1:12,000 in UK)
  • Major risks: Haemorrhage, infection, VTE, bladder/bowel injury
  • Future pregnancy risks: Uterine rupture (VBAC), placenta accreta spectrum
  • Recovery: Hospital stay 2-4 days; full recovery 6-8 weeks
  • VBAC success rate: 72-75% with appropriate selection

Clinical Pearls

"Category 1 = Everyone Runs": A Category 1 CS means immediate threat to life of mother or baby. The team must aim for delivery within 30 minutes — this is "crash CS" territory requiring full team mobilisation.

"Know Your Pfannenstiel": The Pfannenstiel incision (transverse, curved, along skin creases) heals well cosmetically. Joel-Cohen is a straight transverse alternative. Both are in the "bikini line" area.

"Accreta Risk Escalates": The risk of placenta accreta spectrum increases with each repeat CS: 3% after 1 CS, 11% after 2, 40% after 3, 60% after 4+. Always counsel women about future pregnancy implications.

"Spinal Over General": Regional anaesthesia (spinal) is preferred whenever time permits. It allows maternal bonding at delivery, has fewer respiratory complications, and reduces anaesthetic-related mortality.

"Double-Layer Closure": Closing the uterus in two layers is associated with reduced risk of uterine rupture in subsequent pregnancies compared to single-layer closure.

Why This Matters Clinically

Caesarean section is a fundamental obstetric procedure that every obstetrician and many other clinicians must understand. Knowing when CS is indicated, the urgency categories, and the risks allows proper counselling of women and timely decision-making in emergencies. The rising CS rate worldwide has implications for maternal morbidity in future pregnancies, making informed consent and appropriate indication essential.[1,2]


2. Epidemiology

Incidence & Trends

ParameterData
UK CS rate27-30% of all deliveries
WHO recommendation10-15% CS rate for optimal outcomes
Global variation5% (sub-Saharan Africa) to >50% (some Latin American countries)
TrendRising globally over past 50 years
Emergency vs ElectiveApproximately 60% emergency, 40% elective in UK

Indications Distribution

IndicationProportion
Failure to progress (labour dystocia)25-35%
Fetal distress (non-reassuring CTG)20-30%
Previous CS (repeat elective)15-25%
Malpresentation (breech, transverse)10-15%
Maternal request5-10%
Other (placenta praevia, multiple pregnancy, maternal disease)10-20%

Risk Factors for CS

FactorNotes
Previous CSStrongest predictor for repeat CS
Advanced maternal ageIncreased rates >35 years
ObesityBMI >30 associated with increased CS rates
NulliparityHigher rate than multiparous women
Induction of labourSlightly increased CS rate vs spontaneous labour
Multiple pregnancyHigher intervention rates
Maternal comorbidityPre-eclampsia, diabetes, cardiac disease
MacrosomiaEstimated fetal weight >4 kg

3. Pathophysiology

Categories of Urgency (NICE Classification)

CategoryDefinitionTarget DDITypical Scenarios
1Immediate threat to life of woman or fetus<30 minutesCord prolapse, uterine rupture, massive haemorrhage, severe bradycardia
2Maternal or fetal compromise not immediately life-threatening<60 minutesFailure to progress with fetal distress, worsening CTG
3Early delivery needed but no maternal or fetal compromise<75 minutesFailure to progress without distress, elective brought forward
4Elective (planned)ScheduledPlanned repeat CS, placenta praevia, maternal request

Indications for Caesarean Section

Absolute Indications:

  • Placenta praevia major (covering os)
  • Placental abruption with fetal distress
  • Cord prolapse
  • Transverse lie in labour
  • Brow presentation
  • Obstructed labour
  • Uterine rupture

Common Indications:

  • Failure to progress (cervical dilatation or descent)
  • Non-reassuring fetal status (pathological CTG)
  • Breech presentation (after ECV discussion)
  • Previous CS (especially if >2)
  • Maternal request
  • Twin pregnancy (depending on presentation)
  • Severe pre-eclampsia/eclampsia requiring delivery
  • Maternal HIV (if viral load detectable)
  • Active genital herpes at term

Physiological Changes with CS

SystemChanges
CardiovascularAutotransfusion from uterus post-delivery; fluid shifts
RespiratoryGA risk (aspiration, failed intubation)
HaematologicalBlood loss typically 500-1000 mL
HealingUterine scar formation; implications for future pregnancies

4. Clinical Presentation

Indications by Timing

Antenatal (Planned) CS Indications:

Intrapartum (Emergency) CS Indications:

Pre-Operative Assessment

AssessmentDetails
HistoryObstetric history, previous CS details, medical comorbidities
ExaminationPresentation, engagement, cervical dilatation
Fetal monitoringCTG interpretation, biophysical profile
Blood testsFBC, Group & Save (crossmatch if high risk)
Fasting statusWhen last ate/drank (aspiration risk)
ConsentWritten informed consent (unless Cat 1 emergency)

Signs Indicating Emergency CS

[!CAUTION] Red Flags — Category 1 CS Required:

  • Cord prolapse with fetal heart <100 bpm
  • Prolonged fetal bradycardia (<100 bpm for >3 minutes)
  • Uterine rupture (scar pain, loss of contractions, fetal distress)
  • Placental abruption with maternal haemodynamic instability or fetal distress
  • Maternal cardiac arrest (perimortem CS within 4-5 minutes)
  • Eclamptic seizure with non-reassuring fetal status

Placenta praevia (major)
Common presentation.
Previous classical CS or >2 CS
Common presentation.
Breech presentation after counselling
Common presentation.
Maternal request after counselling
Common presentation.
Certain maternal conditions (cardiac, ophthalmological)
Common presentation.
HIV with detectable viral load
Common presentation.
Primary genital herpes in third trimester
Common presentation.
5. Clinical Examination

Pre-Operative Checklist

Maternal Assessment:

  • Vital signs (BP, pulse, temperature, SpO2)
  • Airway assessment (for anaesthesia)
  • Abdominal examination (fundal height, presentation, engagement)
  • Vaginal examination (cervical dilatation, station, presenting part)
  • Check for urinary catheter
  • Fasting status documented

Fetal Assessment:

  • CTG interpretation
  • Presentation confirmation (ultrasound if uncertain)
  • Exclude cord prolapse if membranes ruptured

Documentation:

  • Indication for CS clearly documented
  • Category assigned and justified
  • Consent obtained (or documented reason if not possible)
  • WHO surgical safety checklist completed

Theatre Setup

ItemPreparation
TeamObstetrician, anaesthetist, scrub nurse, ODP, midwife, paediatrician (for Cat 1-2)
EquipmentStandard laparotomy set, sutures, blood available
AnaesthesiaSpinal/epidural tray or GA equipment ready
Neonatal resuscitationResuscitaire checked, neonatologist present if indicated

6. Investigations

Routine Pre-Operative Investigations

InvestigationIndication
FBCBaseline; check Hb especially if anaemic
Group and SaveAll CS (crossmatch if high risk of haemorrhage)
Coagulation screenIf pre-eclampsia, abruption, or bleeding history
U&EIf pre-eclampsia or renal concerns
Blood glucoseIf diabetic or on dextrose infusions

Special Investigations

InvestigationIndication
UltrasoundConfirm presentation if uncertain; localise placenta
MRI pelvisSuspected placenta accreta spectrum (planned)
EchocardiogramMaternal cardiac disease
Fetal blood samplingIf CTG concerning but not Category 1

7. Management

Management Algorithm

            DECISION FOR CAESAREAN SECTION
                        ↓
┌───────────────────────────────────────────────────────────────┐
│                 ASSIGN CATEGORY                               │
├───────────────────────────────────────────────────────────────┤
│  Cat 1: Immediate threat to life → DDI &lt;30 min               │
│  Cat 2: Maternal/fetal compromise → DDI &lt;60 min              │
│  Cat 3: Early delivery needed → DDI &lt;75 min                  │
│  Cat 4: Elective → Scheduled                                  │
└───────────────────────────────────────────────────────────────┘
                        ↓
┌───────────────────────────────────────────────────────────────┐
│                 ANAESTHESIA CHOICE                            │
├───────────────────────────────────────────────────────────────┤
│  CATEGORY 1 (Crash):                                          │
│  ➤ GA if no epidural in situ (fastest)                       │
│  ➤ Top-up epidural if already sited                          │
│                                                               │
│  CATEGORY 2-3:                                                │
│  ➤ Spinal (usually) or epidural top-up                       │
│                                                               │
│  CATEGORY 4 (Elective):                                       │
│  ➤ Spinal (preferred) or CSE                                 │
└───────────────────────────────────────────────────────────────┘
                        ↓
┌───────────────────────────────────────────────────────────────┐
│                 SURGICAL TECHNIQUE                            │
├───────────────────────────────────────────────────────────────┤
│  PREPARATION:                                                 │
│  ➤ Urinary catheter in situ                                  │
│  ➤ Wedge under right hip (left lateral tilt)                 │
│  ➤ Skin prep and sterile draping                             │
│                                                               │
│  INCISION:                                                    │
│  ➤ Skin: Pfannenstiel (curved) or Joel-Cohen (straight)      │
│  ➤ Rectus sheath: Transverse                                 │
│  ➤ Peritoneum: Blunt entry                                   │
│  ➤ Bladder flap: Retract down                                │
│  ➤ Uterine: Transverse lower segment (LSCS)                  │
│                                                               │
│  DELIVERY:                                                    │
│  ➤ Deliver head first, then body                             │
│  ➤ Clamp and cut cord                                        │
│  ➤ Active management of third stage (oxytocin 5 IU slow IV)  │
│  ➤ Deliver placenta                                          │
│                                                               │
│  CLOSURE:                                                     │
│  ➤ Uterus: Double-layer continuous suture                    │
│  ➤ Check haemostasis                                         │
│  ➤ Rectus sheath: Continuous suture                          │
│  ➤ Skin: Subcuticular or staples                             │
└───────────────────────────────────────────────────────────────┘
                        ↓
┌───────────────────────────────────────────────────────────────┐
│                 POST-OPERATIVE CARE                           │
├───────────────────────────────────────────────────────────────┤
│  ➤ Observations: BP, pulse, RR, pain, bleeding, urine output │
│  ➤ VTE prophylaxis: LMWH + TED stockings                     │
│  ➤ Analgesia: Multimodal (paracetamol, NSAIDs, opioids)      │
│  ➤ Early mobilisation (aim within 12-24 hours)               │
│  ➤ Remove catheter at 12-18 hours                            │
│  ➤ Encourage oral intake when tolerated                      │
│  ➤ Breastfeeding support                                     │
│  ➤ Discharge usually day 2-4                                 │
└───────────────────────────────────────────────────────────────┘

Surgical Incision Types

IncisionDescriptionUse
PfannenstielCurved transverse, 2-3 cm above pubic symphysisStandard; good cosmesis
Joel-CohenStraight transverse, 3 cm below ASIS lineFaster; equivalent outcomes
Midline verticalLongitudinal, navel to pubisRapid access; oncology, major trauma
Classical uterineVertical upper segmentExtreme preterm, placenta praevia covering lower segment, transverse lie with back down

Pharmacological Management

PhaseDrugDose
Third stageOxytocin5 IU slow IV bolus + 40 IU in 500 mL infusion
If atonic PPHCarboprost250 mcg IM (repeat to max 8 doses)
Antibiotic prophylaxisCo-amoxiclav OR cefuroxime + metronidazoleSingle dose at skin incision
VTE prophylaxisEnoxaparin OR dalteparinRisk-based dosing; typically 40 mg/4000 IU daily
AnalgesiaParacetamol + NSAIDs + opioids PRNMultimodal approach

8. Complications

Intraoperative Complications

ComplicationIncidenceManagement
Haemorrhage (>1000 mL)5-10%Uterotonic drugs, balloon tamponade, B-Lynch suture, embolisation, hysterectomy
Bladder injury0.1-0.3%Identified and repair; urology if complex
Bowel injury0.05%Surgical repair; may need laparotomy
Uterine extension2-5%Repair carefully; may involve cervix or uterine vessels
Anaesthetic complicationsVariableHypotension (spinal); failed intubation/aspiration (GA)

Early Postoperative Complications (Days)

ComplicationIncidenceManagement
Wound infection2-5%Antibiotics; dressings; rarely debridement
Endometritis3-8%IV antibiotics
UTI2-5%Oral/IV antibiotics
VTE (DVT/PE)0.5-1%Anticoagulation; prophylaxis is key
Ileus2-3%Conservative; NG tube if prolonged
PPH (secondary)1-2%Uterotonics; examination; evacuation if retained products

Long-Term Complications

ComplicationNotes
Scar complicationsKeloid, pain, endometriosis in scar
AdhesionsMay cause pain; complicate future surgery
Uterine rupture (subsequent pregnancy)0.5-1% with TOLAC/VBAC
Placenta accreta spectrumRisk increases with each CS
Chronic pain5-10% have persistent incisional pain
PsychologicalBirth trauma, PTSD particularly with emergency CS

9. Prognosis & Outcomes

Maternal Outcomes

OutcomeCSVaginal Delivery
Mortality (UK)~1:12,000~1:20,000
Severe morbidityHigherLower
Recovery time6-8 weeks1-2 weeks
Future pregnancy risksIncreased (accreta, rupture)Lower

Neonatal Outcomes

OutcomeNotes
Elective CSSlightly higher respiratory morbidity (transient tachypnoea)
Emergency CSMay prevent neonatal hypoxia from prolonged labour
Optimal timing≥39 weeks for elective CS to reduce respiratory complications

VBAC (Vaginal Birth After Caesarean)

FactorImpact
Success rate72-75% with appropriate selection
Uterine rupture risk0.5-1%
Favourable factorsPrevious vaginal delivery, spontaneous labour, non-recurrent indication
Unfavourable factorsNo prior vaginal birth, repeat indication (CPD), induction

10. Evidence & Guidelines

Key Guidelines

GuidelineOrganisationYearKey Points
Caesarean Birth (NG192)NICE2021Categories, indications, consent, technique
Caesarean Section (Green-top 7)RCOG2021Surgical standards and complications
VBAC (Green-top 45)RCOG2015Trial of labour after CS guidance

Landmark Trials

Term Breech Trial (Hannah et al. 2000)

  • RCT comparing planned CS vs vaginal birth for breech
  • CS reduced perinatal mortality/morbidity
  • Changed practice: CS now recommended for term breech
  • PMID: 11052579

CAESAR Trial (2010)

  • Single vs double-layer uterine closure
  • No significant difference in short-term outcomes
  • Long-term follow-up suggested double-layer may reduce rupture risk
  • PMID: 20598272

CORONIS Trial (2013)

  • Large factorial RCT of CS techniques
  • Blunt vs sharp entry, single vs double-layer closure, etc.
  • Informed current practice guidelines
  • PMID: 23953766

Evidence Strength

InterventionLevelEvidence
Antibiotic prophylaxis at incision1aMeta-analysis
Double-layer uterine closure2aRCTs, cohort studies
Spinal over GA (when time permits)1bRCTs
VTE prophylaxis post-CS1aGuidelines, systematic reviews

11. Patient/Layperson Explanation

What is a Caesarean Section?

A caesarean section (also called C-section or CS) is an operation to deliver your baby through a cut in your tummy and womb. It's a very common procedure — in the UK, about 1 in 4 babies are born this way.

Why might I need one?

Some C-sections are planned in advance (elective), and others happen during labour (emergency).

Planned reasons include:

  • Your baby is in a bottom-first position (breech)
  • You've had C-sections before
  • Your placenta is covering your cervix
  • Personal preference after counselling

Emergency reasons include:

  • Labour isn't progressing
  • Your baby shows signs of distress
  • The umbilical cord comes out first (cord prolapse)

What happens during the operation?

  • You'll usually have a spinal anaesthetic, meaning you're awake but can't feel from the waist down
  • A cut is made across your lower tummy (along the "bikini line")
  • Your baby is lifted out of your womb
  • The whole surgery takes about 45-60 minutes
  • You can usually hold your baby within minutes of delivery

What about recovery?

  • You'll stay in hospital for 2-4 days
  • The cut usually heals well but takes 6-8 weeks to fully recover
  • Avoid driving for 4-6 weeks
  • You can breastfeed normally
  • Tell your doctor in future pregnancies that you've had a C-section

What are the risks?

Like any operation, there are some risks:

  • Infection
  • Bleeding (rarely needing transfusion)
  • Blood clots (prevented with injections and compression stockings)
  • Injury to bladder or bowel (rare)
  • Risks in future pregnancies (placenta problems, uterine rupture)

Most C-sections go smoothly, and serious complications are rare.


12. References

Guidelines

  1. National Institute for Health and Care Excellence (NICE). Caesarean birth (NG192). 2021. nice.org.uk/guidance/ng192

  2. Royal College of Obstetricians and Gynaecologists. Caesarean Section (Green-top Guideline No. 7). 2021. rcog.org.uk

  3. Royal College of Obstetricians and Gynaecologists. Birth After Previous Caesarean Birth (Green-top Guideline No. 45). 2015. rcog.org.uk

Key Trials

  1. Hannah ME, Hannah WJ, Hewson SA, et al. Planned caesarean section versus planned vaginal birth for breech presentation at term: a randomised multicentre trial. Lancet. 2000;356(9239):1375-1383. PMID: 11052579

  2. CAESAR Collaborative. Caesarean section surgical techniques: a randomised factorial trial (CAESAR). BJOG. 2010;117(11):1366-1376. PMID: 20598272

  3. CORONIS Collaborative Group. Caesarean section surgical techniques (CORONIS): a fractional, factorial, unmasked, randomised controlled trial. Lancet. 2013;382(9888):234-248. PMID: 23953766

Reviews

  1. Betran AP, Ye J, Moller AB, et al. Trends and projections of caesarean section rates: global and regional estimates. BMJ Glob Health. 2021;6(6):e005671. PMID: 34130991

  2. Landon MB, Grobman WA. Vaginal birth after cesarean delivery. N Engl J Med. 2017;376(20):1968-1978. PMID: 28514617


13. Examination Focus

High-Yield Exam Topics

TopicKey Points
Category classificationCat 1 (<30 min, crash); Cat 2 (<60 min); Cat 3 (<75 min); Cat 4 (elective)
IndicationsFetal distress, failure to progress, malpresentation, previous CS, placenta praevia
Anaesthesia choiceSpinal preferred; GA for Cat 1 without epidural
Surgical techniquePfannenstiel skin, transverse lower segment uterine, double-layer closure
ComplicationsHaemorrhage, infection, VTE, bladder injury, future pregnancy risks
VBAC72-75% success; uterine rupture risk 0.5-1%

Sample Viva Questions

Q1: A primigravida at 38 weeks in labour for 18 hours is 5 cm dilated and has been that way for 4 hours. CTG shows recurrent late decelerations. What is your management?

Model Answer: This presentation suggests failure to progress in the first stage of labour with non-reassuring fetal status. The recurrent late decelerations indicate fetal compromise. I would classify this as a Category 2 CS (maternal/fetal compromise but not immediately life-threatening). Management: Inform the consultant and anaesthetist. Prepare for CS within 60 minutes. Spinal anaesthesia if feasible (time permits). If CTG deteriorates to prolonged bradycardia, I would escalate to Category 1 requiring delivery within 30 minutes, potentially under GA.

Q2: What are the long-term risks of caesarean section for future pregnancies?

Model Answer: Key long-term risks include:

  1. Uterine rupture: 0.5-1% risk with VBAC/TOLAC; higher if classical incision
  2. Placenta accreta spectrum: Risk increases with each CS (3% after 1, 11% after 2, 40% after 3+)
  3. Placenta praevia: Increased risk due to uterine scarring
  4. Adhesions: May complicate future surgery
  5. Increased repeat CS rate: Many women require repeat CS
  6. Ectopic pregnancy in scar: Rare but recognised

Counselling women about these risks is essential, especially those desiring large families.

Q3: What are the anaesthetic options for caesarean section and when would you choose general anaesthesia?

Model Answer: Options include:

  1. Spinal anaesthesia: Single injection; rapid onset; preferred for most CS
  2. Epidural anaesthesia: If already sited for labour; top-up for CS
  3. Combined spinal-epidural (CSE): Flexibility of both
  4. General anaesthesia: Fastest; patient asleep

I would choose GA for:

  • Category 1 CS without epidural in situ (fastest)
  • Maternal refusal of regional
  • Contraindications to regional (coagulopathy, infection, raised ICP)
  • Failed regional technique
  • Maternal preference

However, GA carries higher risks (aspiration, failed intubation) and precludes maternal bonding at delivery.

Common Exam Errors

ErrorCorrect Approach
Confusing category timingsCat 1 <30 min, Cat 2 <60 min, Cat 3 <75 min
Choosing GA for all emergenciesGA only for Cat 1 without epidural; spinal often feasible for Cat 2-3
Single-layer closure recommendationDouble-layer closure reduces rupture risk in subsequent pregnancy
Forgetting antibiotic timingGive antibiotics at skin incision (before delivery)
Not counselling about future pregnancy risksAlways discuss accreta spectrum risk with increasing CS numbers

Last Reviewed: 2025-12-24 | MedVellum Editorial Team


Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. Clinical decisions should account for individual patient circumstances. Always consult appropriate specialists.

Last updated: 2025-12-24

At a Glance

EvidenceHigh
Last Updated2025-12-24

Red Flags

  • Category 1 CS (immediate threat to life of mother or baby)
  • Placenta accreta spectrum (increasing risk with multiple prior CS)
  • Uterine rupture (especially VBAC)
  • Massive obstetric haemorrhage
  • Cord prolapse
  • Uterine hyperstimulation with fetal distress

Clinical Pearls

  • General (for Cat 1/emergencies)
  • **"Double-Layer Closure"**: Closing the uterus in two layers is associated with reduced risk of uterine rupture in subsequent pregnancies compared to single-layer closure.
  • **Red Flags — Category 1 CS Required:**
  • - Cord prolapse with fetal heart &lt;100 bpm
  • - Prolonged fetal bradycardia (&lt;100 bpm for &gt;3 minutes)

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines