Cardiac Tamponade in Adults
Summary
Cardiac tamponade is a life-threatening condition caused by accumulation of fluid in the pericardial space, leading to compression of the heart and impaired filling. It is a clinical diagnosis based on haemodynamic compromise — treat urgently with pericardiocentesis. Causes include malignancy, infection (TB, viral), post-MI, trauma, and iatrogenic (post-procedure). Even small effusions can cause tamponade if rapidly accumulating.
Key Facts
- Definition: Pericardial fluid causing haemodynamic compromise
- Beck's triad: Hypotension, Raised JVP, Muffled heart sounds
- Pulsus paradoxus: SBP drop greater than 10 mmHg on inspiration
- Treatment: Pericardiocentesis (urgent) or surgical drainage
- Volume matters less than rate: Slow effusions may reach 1L+ without tamponade
- PEA arrest: Tamponade is a reversible cause (4 Hs and 4 Ts)
Clinical Pearls
Beck's triad is specific but insensitive — you may not see all three
In trauma, tamponade is often from haemopericardium — may need thoracotomy
Electrical alternans (alternating QRS height) is classic but uncommon
Why This Matters Clinically
Tamponade is a treatable cause of PEA arrest and shock. Rapid recognition and drainage saves lives. Echocardiography is diagnostic but should not delay treatment if diagnosis is clinically clear.
Causes
| Cause | Examples |
|---|---|
| Malignancy | Lung, Breast, Lymphoma (most common in developed countries) |
| Infection | TB (common globally), Viral, Bacterial |
| Iatrogenic | Post-cardiac surgery, Catheterisation, Pacemaker insertion |
| Post-MI | Ventricular rupture, Dressler's syndrome |
| Trauma | Penetrating or blunt chest injury |
| Autoimmune | SLE, RA |
| Uraemia | Chronic kidney disease |
| Aortic dissection | Extension into pericardium |
| Idiopathic |
Demographics
- Any age
- Malignancy more common in elderly
- TB common in endemic areas
Mechanism
1. Pericardial Fluid Accumulation
- Inflammatory, malignant, traumatic, or transudative
- Rate of accumulation more important than volume
2. Increased Intrapericardial Pressure
- Exceeds normal filling pressures
- Right heart compressed first (thinner wall)
3. Impaired Cardiac Filling
- Reduced diastolic filling
- Equalisation of diastolic pressures across chambers
- Reduced stroke volume
4. Compensatory Mechanisms
- Tachycardia
- Peripheral vasoconstriction
- Eventually fail → Hypotension, Shock, PEA arrest
Pulsus Paradoxus
- Normal: SBP drops less than 10 mmHg on inspiration
- Tamponade: Drop greater than 10 mmHg
- Mechanism: Increased venous return to RV on inspiration → RV expansion → LV compression (fixed pericardial space) → Reduced LV output
Why Rate Matters More Than Volume
| Scenario | Volume | Outcome |
|---|---|---|
| Chronic effusion (slow) | Greater than 1L | May be asymptomatic (pericardium stretches) |
| Acute haemopericardium | 100-200ml | Tamponade (pericardium cannot stretch) |
Cardiac Tamponade — Emergency Management
Clinical Diagnosis:
- Beck's Triad: Hypotension + Elevated JVP + Muffled heart sounds
- Pulsus paradoxus: SBP drop greater than 10 mmHg on inspiration
- Tachycardia
- Cool peripheries
Immediate Actions:
-
Call for Help
- Cardiology, Cardiothoracic surgery
- Prepare for pericardiocentesis
-
IV Access and Fluids
- Fluid bolus may temporarily improve filling
- Do NOT over-resuscitate — may worsen tamponade
-
Avoid Positive Pressure Ventilation
- Reduces venous return, worsens haemodynamics
- Consider awake pericardiocentesis before intubation
-
Pericardiocentesis
- Subxiphoid approach (most common)
- Ultrasound guided (if available)
- Insert needle towards left shoulder at 45 degrees
- Aspirate — even 30-50ml may dramatically improve haemodynamics
- Consider leaving drain in situ
-
Surgical Drainage
- Indicated if: Purulent effusion, Trauma (haemopericardium), Recurrent effusion, Aortic dissection
- Pericardial window or pericardiectomy
[!WARNING] In traumatic tamponade, pericardiocentesis is often only a temporising measure. Definitive treatment is thoracotomy.
PEA Arrest
- Tamponade is one of the "4 Ts" (reversible cause)
- Consider if PEA with distended neck veins
- Emergency pericardiocentesis during CPR
- May need resuscitative thoracotomy
History
- Dyspnoea — progressive
- Chest discomfort — may be positional
- Symptoms of underlying cause — fever (infection), weight loss (malignancy), recent procedure
Physical Examination
Beck's Triad:
- Hypotension (narrow pulse pressure)
- Elevated JVP (often very high)
- Muffled heart sounds
Pulsus Paradoxus:
- Measure BP with cuff
- Note SBP when first Korotkoff sound heard on expiration only
- Note SBP when heard throughout respiratory cycle
- Difference greater than 10 mmHg = positive
Other Signs:
- Tachycardia
- Cool, clammy peripheries
- Reduced urine output
- Kussmaul's sign (JVP rises on inspiration) — less common in tamponade
Bedside
ECG:
- Low voltage QRS
- Electrical alternans (alternating QRS amplitude)
- Sinus tachycardia
- May have features of pericarditis (diffuse ST elevation, PR depression)
Echocardiography (POCUS):
- Gold standard for diagnosis
- Pericardial effusion (anechoic space)
- Right atrial and RV diastolic collapse (specific for tamponade)
- Dilated IVC with reduced respiratory variation
- Swinging heart
Laboratory
| Test | Purpose |
|---|---|
| Troponin | Myopericarditis |
| Inflammatory markers | Infection |
| TFTs | Hypothyroidism (rare cause) |
| Autoimmune screen | SLE, RA |
| Pericardial fluid analysis | Cell count, Protein, LDH, Glucose, Cytology, Culture, AFB |
Imaging
CXR:
- Cardiomegaly ("water bottle" heart) if large effusion
- May be normal if acute
CT Chest:
- Characterise effusion
- Look for malignancy, dissection
By Size (Echocardiography)
| Size | Description |
|---|---|
| Small | Less than 10mm echo-free space |
| Moderate | 10-20mm |
| Large | Greater than 20mm |
By Haemodynamic Effect
| Status | Features |
|---|---|
| Effusion without tamponade | No haemodynamic compromise |
| Tamponade physiology | Echo signs of chamber collapse |
| Clinical tamponade | Haemodynamic compromise |
By Aetiology
- Transudative (HF, hypoalbuminaemia)
- Exudative (infection, malignancy, autoimmune)
- Haemorrhagic (trauma, post-MI rupture, dissection)
Acute Management
1. Supportive Measures
- IV fluids (cautious bolus)
- Avoid positive pressure ventilation if possible
- Inotropes (limited benefit but may temporise)
2. Pericardiocentesis
- Indication: Clinical tamponade, haemodynamic compromise
- Technique: Subxiphoid approach, ultrasound guidance
- Drainage: May leave pigtail catheter for ongoing drainage
3. Surgical Options
| Procedure | Indication |
|---|---|
| Pericardial window | Recurrent effusion, malignancy |
| Pericardiectomy | Constrictive pericarditis |
| Thoracotomy | Trauma, post-MI rupture |
Treatment of Underlying Cause
| Cause | Treatment |
|---|---|
| Malignancy | Oncology referral, chemotherapy, pericardial window |
| TB | Anti-TB therapy |
| Viral | NSAIDs, Colchicine |
| Autoimmune | Steroids, DMARDs |
| Uraemia | Dialysis |
| Iatrogenic | Drain and monitor |
Post-Procedure
- Repeat echo to confirm resolution
- Investigate underlying cause
- Consider pericardial window if recurrent
Of Tamponade
| Complication | Features |
|---|---|
| PEA arrest | Cardiovascular collapse |
| Multi-organ failure | Prolonged poor perfusion |
| Death | If untreated |
Of Pericardiocentesis
| Complication | Prevention |
|---|---|
| Cardiac puncture | Ultrasound guidance |
| Pneumothorax | Correct technique |
| Arrhythmia | Monitor |
| Infection | Aseptic technique |
Short-Term
- Excellent if treated promptly
- Dependent on underlying cause
- Malignant effusions have poorer prognosis
Recurrence
- Common with malignancy
- Pericardial window reduces recurrence
Key Guidelines
- ESC Guidelines for Pericardial Diseases (2015) — European standard
- AHA Scientific Statement on Pericardial Diseases
Evidence Base
- Pericardiocentesis is standard of care for tamponade
- Ultrasound guidance reduces complications
- Surgical drainage preferred for traumatic and purulent effusions
Evidence Levels
| Intervention | Level |
|---|---|
| Pericardiocentesis for tamponade | Consensus |
| Ultrasound guidance | 2a |
| Surgical drainage for trauma/purulent | Consensus |
| Pericardial window for malignancy | 2b |
What is Cardiac Tamponade?
Cardiac tamponade happens when fluid builds up in the sac around your heart (the pericardium). This fluid presses on your heart and stops it from filling properly, which can be life-threatening.
What Are the Symptoms?
- Shortness of breath
- Chest discomfort
- Feeling faint or dizzy
- Fatigue
What Causes It?
- Infection around the heart
- Cancer
- After heart surgery or procedures
- Injury to the chest
- Inflammation
How Is It Treated?
- Draining the fluid — using a needle (pericardiocentesis) or surgery
- Treatment of the underlying cause
- Close monitoring
After Treatment
- You will have repeat scans to check the fluid doesn't return
- Treatment for whatever caused the fluid buildup
- Follow-up with a cardiologist
Primary Guidelines
- Adler Y, et al. 2015 ESC Guidelines for the diagnosis and management of pericardial diseases. Eur Heart J. 2015;36(42):2921-64. PMID: 26320112