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Rheumatology
Emergency Medicine
Primary Care
Cardiology

Costochondritis

High EvidenceUpdated: 2025-12-22

On This Page

Red Flags

  • Cardiac chest pain (exclude MI, ACS)
  • Pulmonary embolism
  • Aortic dissection
  • Fever with chest pain (consider infective cause)
  • New onset in elderly with risk factors
Overview

Costochondritis

1. Clinical Overview

Summary

Costochondritis is inflammation of the costochondral or costosternal joints, causing localised anterior chest wall pain. It is one of the most common causes of non-cardiac chest pain, accounting for 13-36% of emergency department chest pain presentations. The hallmark feature is reproducible tenderness on palpation of the affected costochondral junctions, most commonly the 2nd-5th ribs. Tietze syndrome is a related but distinct condition with visible/palpable swelling. Costochondritis is a diagnosis of exclusion - cardiac and pulmonary causes must be ruled out first. Treatment is reassurance and NSAIDs; it is self-limiting.

Key Facts

  • Definition: Inflammation of costochondral/costosternal junctions
  • Incidence: 13-36% of ED chest pain presentations
  • Peak Age: 20-40 years
  • Location: Most commonly 2nd-5th costochondral junctions (unilateral)
  • Key Sign: Reproducible tenderness on palpation
  • Tietze Syndrome: Costochondritis + Visible swelling (distinct entity)
  • Treatment: Reassurance, NSAIDs; Self-limiting

Clinical Pearls

"Diagnosis of Exclusion": Costochondritis is benign, but chest pain is dangerous until proven otherwise. Always exclude cardiac, pulmonary, and aortic pathology first.

"Reproduce the Pain": The key to diagnosis is reproducing the patient's exact pain with palpation. If you can't reproduce it, think again.

"Tietze is Swollen, Costochondritis is Not": Tietze syndrome has visible/palpable swelling, usually affecting a single rib (2nd or 3rd). Classic costochondritis has no swelling.

"ECG First, Reassure Later": Even if you suspect costochondritis, always do an ECG in chest pain. It takes 2 minutes and could save a life.


2. Epidemiology

Incidence

  • 13-36% of ED chest pain presentations
  • 10-30% of primary care chest pain
  • Very common in young adults

Demographics

  • Peak age: 20-40 years
  • F:M = 70:30
  • More common in Hispanics in some studies

Risk Factors

FactorNotes
Recent respiratory infectionExcessive coughing
Physical exertionOveruse/strain
TraumaDirect blow to chest
Repetitive movementsLifting, carrying
ArthritisInflammatory conditions
Post-sternotomyCardiac surgery

Causes

  • Often idiopathic
  • Repetitive minor trauma
  • Viral upper respiratory tract infections
  • Associated with fibromyalgia
  • Rarely, seronegative spondyloarthropathy

3. Pathophysiology

Anatomy

  • Costochondral junctions: Where ribs meet costal cartilages
  • Costosternal joints: Where costal cartilages meet sternum
  • True ribs (1-7) articulate directly with sternum
  • Ribs 2-7 have synovial costosternal joints

Mechanism

  1. Microtrauma or inflammation at costochondral/costosternal junction
  2. Local inflammatory response
  3. Pain - Sharp, localized, reproducible
  4. No visible swelling (unlike Tietze)

Costochondritis vs Tietze Syndrome

FeatureCostochondritisTietze Syndrome
Age20-40 (any age)<40
SwellingNonePresent (single rib)
SiteMultiple (2nd-5th)Usually single (2nd or 3rd)
PrevalenceCommonRare

4. Clinical Presentation

Symptoms

FeatureDescription
Pain characterSharp, stabbing, or aching
LocationAnterior chest wall, parasternal
LateralityUsually unilateral (can be bilateral)
Aggravating factorsDeep breathing, movement, coughing, palpation
DurationDays to weeks (can be months)
Associated symptomsUsually none; no dyspnoea, palpitations

Pattern

What Costochondritis is NOT

FeatureSuggests NOT Costochondritis
Exertional painAngina
Central crushing painMI
Pleuritic with dyspnoeaPE
Tearing pain to backAortic dissection
FeverInfection
New in elderlySerious pathology

Pain worse with movement, breathing, coughing
Common presentation.
Pain reproducible on palpation
Common presentation.
No radiation typically (unless patient anxious)
Common presentation.
5. Clinical Examination

Vital Signs

  • Normal (if abnormal, consider alternative diagnosis)

Inspection

  • Chest wall usually normal
  • Look for swelling (if present = Tietze syndrome)
  • No erythema typically

Palpation

Key Point: Reproduce the pain

FindingSignificance
Point tenderness over costochondral junctionHighly suggestive
Pain reproduced = patient's symptomDiagnostic
Multiple sites affectedCommon (2nd-5th ribs)
No swellingCostochondritis (vs Tietze)

Auscultation

  • Heart sounds normal
  • Lung sounds normal

Red Flag Features (Exclude)

FindingConsider
HypotensionMI, PE, aortic dissection
Tachycardia, desaturationPE
MurmurCardiac pathology
Unequal pulsesAortic dissection
FeverInfective cause

6. Investigations

First-Line

TestPurpose
ECGExclude MI/ischaemia (MUST do in all chest pain)
ObservationsExclude hemodynamic instability

Second-Line (If Concerned)

TestWhen to Consider
TroponinIf any concern for ACS
D-dimerIf PE suspected (use Wells score)
CXRIf respiratory symptoms, trauma
Blood tests (FBC, CRP)If fever, suspected infection/inflammation

Imaging

  • Usually NOT needed if typical presentation
  • X-ray: Normal in costochondritis
  • CT: Only if excluding serious pathology

Diagnostic Criteria

  • Clinical diagnosis
  • Reproducible tenderness on palpation
  • Exclusion of cardiac/pulmonary causes

7. Management

Initial Assessment

┌──────────────────────────────────────────────────────────┐
│   CHEST PAIN: COSTOCHONDRITIS SUSPECTED                  │
├──────────────────────────────────────────────────────────┤
│                                                          │
│  STEP 1: EXCLUDE RED FLAGS                                │
│  • ECG (mandatory)                                       │
│  • Vital signs                                           │
│  • Cardiac risk factors                                  │
│  • Red flag symptoms (dyspnoea, syncope, sweating)       │
│                                                          │
│  STEP 2: CONFIRM DIAGNOSIS                                │
│  • Reproduce pain on palpation                           │
│  • Typical location (2nd-5th costochondral junction)     │
│  • No alternative explanation                            │
│                                                          │
│  STEP 3: MANAGE                                           │
│  • Reassurance (explain benign nature)                   │
│  • NSAIDs (ibuprofen 400mg TDS for 1-2 weeks)            │
│  • Heat/ice locally                                      │
│  • Paracetamol if NSAID contraindicated                  │
│                                                          │
└──────────────────────────────────────────────────────────┘

Conservative Management

  • Reassurance: Most important - explain benign, self-limiting nature
  • NSAIDs: Ibuprofen 400mg TDS or Naproxen 500mg BD for 1-2 weeks
  • Topical NSAIDs: Alternative for those who can't take oral
  • Heat or ice: Local application
  • Avoid aggravating movements: Temporarily

Refractory Cases

  • Physiotherapy
  • Steroid injection (rare, controversial)
  • Review diagnosis

8. Complications

Of Condition

  • Chronic pain (rarely)
  • Anxiety about chest pain
  • No serious complications

Of Treatment

  • NSAID side effects (GI upset, renal)

9. Prognosis & Outcomes

Natural History

  • Self-limiting in most cases
  • Duration: Days to weeks (occasionally months)
  • Recurrence possible

With Treatment

  • Symptoms usually improve within 1-2 weeks
  • Full resolution expected

Factors Affecting Prognosis

GoodPoor
Young ageChronic symptoms
Acute onsetFibromyalgia
Single episodeRecurrent episodes

10. Evidence & Guidelines

Key Guidelines

  1. NICE CKS: Chest Pain
  2. European Society of Cardiology: Chest Pain Guidelines

Key Evidence

Epidemiology

  • Studies show 13-36% of ED chest pain is musculoskeletal
  • Costochondritis most common MSK cause

Treatment

  • Limited RCT evidence (benign, self-limiting)
  • NSAIDs widely recommended based on clinical practice

11. Patient/Layperson Explanation

What is Costochondritis?

Costochondritis is pain and tenderness where your ribs join the breastbone (sternum). It's caused by inflammation of the cartilage that connects these bones. It's a very common cause of chest pain and is NOT related to your heart.

What Causes It?

Often the cause is unknown. It can be triggered by:

  • Strain from heavy lifting or exercise
  • Severe coughing (e.g., after a cold)
  • Minor injuries to the chest

Is it Serious?

No. Costochondritis is harmless and usually gets better on its own. However, chest pain can have serious causes, so it's important to see a doctor to rule out heart or lung problems.

How Do I Know It's Costochondritis?

Your doctor will press on your chest and if this reproduces your pain exactly, it's likely costochondritis. They may do an ECG and blood tests just to be sure it's not your heart.

How is it Treated?

  • Reassurance: Knowing it's not your heart often helps!
  • Anti-inflammatory painkillers: Ibuprofen or naproxen for 1-2 weeks
  • Heat or ice packs: Applied to the sore area
  • Avoid aggravating activities: Until it settles

How Long Does it Last?

Most people feel better within 1-2 weeks. Sometimes it takes a few months. It may come back occasionally but this is not dangerous.

When to Seek Help

See a doctor urgently if you have:

  • Crushing chest pain, especially with exertion
  • Pain spreading to arm, jaw, or back
  • Shortness of breath
  • Feeling faint or sweaty with chest pain
  • Fever

12. References

Primary Guidelines

  1. NICE Clinical Knowledge Summaries. Chest Pain. cks.nice.org.uk
  2. ESC Guidelines. Management of Acute Coronary Syndromes. European Heart Journal. 2023.

Key Studies

  1. Proulx AM, Zryd TW. Costochondritis: diagnosis and treatment. Am Fam Physician. 2009;80(6):617-620. PMID: 19817327
  2. Disla E, et al. Costochondritis: a prospective analysis in an emergency department setting. Arch Intern Med. 1994;154(21):2466-2469. PMID: 7979843

Last updated: 2025-12-22

At a Glance

EvidenceHigh
Last Updated2025-12-22

Red Flags

  • Cardiac chest pain (exclude MI, ACS)
  • Pulmonary embolism
  • Aortic dissection
  • Fever with chest pain (consider infective cause)
  • New onset in elderly with risk factors

Clinical Pearls

  • **"Diagnosis of Exclusion"**: Costochondritis is benign, but chest pain is dangerous until proven otherwise. Always exclude cardiac, pulmonary, and aortic pathology first.
  • **"Reproduce the Pain"**: The key to diagnosis is reproducing the patient's exact pain with palpation. If you can't reproduce it, think again.
  • **"Tietze is Swollen, Costochondritis is Not"**: Tietze syndrome has visible/palpable swelling, usually affecting a single rib (2nd or 3rd). Classic costochondritis has no swelling.
  • **"ECG First, Reassure Later"**: Even if you suspect costochondritis, always do an ECG in chest pain. It takes 2 minutes and could save a life.

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines