Costochondritis
Summary
Costochondritis is inflammation of the costochondral or costosternal joints, causing localised anterior chest wall pain. It is one of the most common causes of non-cardiac chest pain, accounting for 13-36% of emergency department chest pain presentations. The hallmark feature is reproducible tenderness on palpation of the affected costochondral junctions, most commonly the 2nd-5th ribs. Tietze syndrome is a related but distinct condition with visible/palpable swelling. Costochondritis is a diagnosis of exclusion - cardiac and pulmonary causes must be ruled out first. Treatment is reassurance and NSAIDs; it is self-limiting.
Key Facts
- Definition: Inflammation of costochondral/costosternal junctions
- Incidence: 13-36% of ED chest pain presentations
- Peak Age: 20-40 years
- Location: Most commonly 2nd-5th costochondral junctions (unilateral)
- Key Sign: Reproducible tenderness on palpation
- Tietze Syndrome: Costochondritis + Visible swelling (distinct entity)
- Treatment: Reassurance, NSAIDs; Self-limiting
Clinical Pearls
"Diagnosis of Exclusion": Costochondritis is benign, but chest pain is dangerous until proven otherwise. Always exclude cardiac, pulmonary, and aortic pathology first.
"Reproduce the Pain": The key to diagnosis is reproducing the patient's exact pain with palpation. If you can't reproduce it, think again.
"Tietze is Swollen, Costochondritis is Not": Tietze syndrome has visible/palpable swelling, usually affecting a single rib (2nd or 3rd). Classic costochondritis has no swelling.
"ECG First, Reassure Later": Even if you suspect costochondritis, always do an ECG in chest pain. It takes 2 minutes and could save a life.
Incidence
- 13-36% of ED chest pain presentations
- 10-30% of primary care chest pain
- Very common in young adults
Demographics
- Peak age: 20-40 years
- F:M = 70:30
- More common in Hispanics in some studies
Risk Factors
| Factor | Notes |
|---|---|
| Recent respiratory infection | Excessive coughing |
| Physical exertion | Overuse/strain |
| Trauma | Direct blow to chest |
| Repetitive movements | Lifting, carrying |
| Arthritis | Inflammatory conditions |
| Post-sternotomy | Cardiac surgery |
Causes
- Often idiopathic
- Repetitive minor trauma
- Viral upper respiratory tract infections
- Associated with fibromyalgia
- Rarely, seronegative spondyloarthropathy
Anatomy
- Costochondral junctions: Where ribs meet costal cartilages
- Costosternal joints: Where costal cartilages meet sternum
- True ribs (1-7) articulate directly with sternum
- Ribs 2-7 have synovial costosternal joints
Mechanism
- Microtrauma or inflammation at costochondral/costosternal junction
- Local inflammatory response
- Pain - Sharp, localized, reproducible
- No visible swelling (unlike Tietze)
Costochondritis vs Tietze Syndrome
| Feature | Costochondritis | Tietze Syndrome |
|---|---|---|
| Age | 20-40 (any age) | <40 |
| Swelling | None | Present (single rib) |
| Site | Multiple (2nd-5th) | Usually single (2nd or 3rd) |
| Prevalence | Common | Rare |
Symptoms
| Feature | Description |
|---|---|
| Pain character | Sharp, stabbing, or aching |
| Location | Anterior chest wall, parasternal |
| Laterality | Usually unilateral (can be bilateral) |
| Aggravating factors | Deep breathing, movement, coughing, palpation |
| Duration | Days to weeks (can be months) |
| Associated symptoms | Usually none; no dyspnoea, palpitations |
Pattern
What Costochondritis is NOT
| Feature | Suggests NOT Costochondritis |
|---|---|
| Exertional pain | Angina |
| Central crushing pain | MI |
| Pleuritic with dyspnoea | PE |
| Tearing pain to back | Aortic dissection |
| Fever | Infection |
| New in elderly | Serious pathology |
Vital Signs
- Normal (if abnormal, consider alternative diagnosis)
Inspection
- Chest wall usually normal
- Look for swelling (if present = Tietze syndrome)
- No erythema typically
Palpation
Key Point: Reproduce the pain
| Finding | Significance |
|---|---|
| Point tenderness over costochondral junction | Highly suggestive |
| Pain reproduced = patient's symptom | Diagnostic |
| Multiple sites affected | Common (2nd-5th ribs) |
| No swelling | Costochondritis (vs Tietze) |
Auscultation
- Heart sounds normal
- Lung sounds normal
Red Flag Features (Exclude)
| Finding | Consider |
|---|---|
| Hypotension | MI, PE, aortic dissection |
| Tachycardia, desaturation | PE |
| Murmur | Cardiac pathology |
| Unequal pulses | Aortic dissection |
| Fever | Infective cause |
First-Line
| Test | Purpose |
|---|---|
| ECG | Exclude MI/ischaemia (MUST do in all chest pain) |
| Observations | Exclude hemodynamic instability |
Second-Line (If Concerned)
| Test | When to Consider |
|---|---|
| Troponin | If any concern for ACS |
| D-dimer | If PE suspected (use Wells score) |
| CXR | If respiratory symptoms, trauma |
| Blood tests (FBC, CRP) | If fever, suspected infection/inflammation |
Imaging
- Usually NOT needed if typical presentation
- X-ray: Normal in costochondritis
- CT: Only if excluding serious pathology
Diagnostic Criteria
- Clinical diagnosis
- Reproducible tenderness on palpation
- Exclusion of cardiac/pulmonary causes
Initial Assessment
┌──────────────────────────────────────────────────────────┐
│ CHEST PAIN: COSTOCHONDRITIS SUSPECTED │
├──────────────────────────────────────────────────────────┤
│ │
│ STEP 1: EXCLUDE RED FLAGS │
│ • ECG (mandatory) │
│ • Vital signs │
│ • Cardiac risk factors │
│ • Red flag symptoms (dyspnoea, syncope, sweating) │
│ │
│ STEP 2: CONFIRM DIAGNOSIS │
│ • Reproduce pain on palpation │
│ • Typical location (2nd-5th costochondral junction) │
│ • No alternative explanation │
│ │
│ STEP 3: MANAGE │
│ • Reassurance (explain benign nature) │
│ • NSAIDs (ibuprofen 400mg TDS for 1-2 weeks) │
│ • Heat/ice locally │
│ • Paracetamol if NSAID contraindicated │
│ │
└──────────────────────────────────────────────────────────┘
Conservative Management
- Reassurance: Most important - explain benign, self-limiting nature
- NSAIDs: Ibuprofen 400mg TDS or Naproxen 500mg BD for 1-2 weeks
- Topical NSAIDs: Alternative for those who can't take oral
- Heat or ice: Local application
- Avoid aggravating movements: Temporarily
Refractory Cases
- Physiotherapy
- Steroid injection (rare, controversial)
- Review diagnosis
Of Condition
- Chronic pain (rarely)
- Anxiety about chest pain
- No serious complications
Of Treatment
- NSAID side effects (GI upset, renal)
Natural History
- Self-limiting in most cases
- Duration: Days to weeks (occasionally months)
- Recurrence possible
With Treatment
- Symptoms usually improve within 1-2 weeks
- Full resolution expected
Factors Affecting Prognosis
| Good | Poor |
|---|---|
| Young age | Chronic symptoms |
| Acute onset | Fibromyalgia |
| Single episode | Recurrent episodes |
Key Guidelines
- NICE CKS: Chest Pain
- European Society of Cardiology: Chest Pain Guidelines
Key Evidence
Epidemiology
- Studies show 13-36% of ED chest pain is musculoskeletal
- Costochondritis most common MSK cause
Treatment
- Limited RCT evidence (benign, self-limiting)
- NSAIDs widely recommended based on clinical practice
What is Costochondritis?
Costochondritis is pain and tenderness where your ribs join the breastbone (sternum). It's caused by inflammation of the cartilage that connects these bones. It's a very common cause of chest pain and is NOT related to your heart.
What Causes It?
Often the cause is unknown. It can be triggered by:
- Strain from heavy lifting or exercise
- Severe coughing (e.g., after a cold)
- Minor injuries to the chest
Is it Serious?
No. Costochondritis is harmless and usually gets better on its own. However, chest pain can have serious causes, so it's important to see a doctor to rule out heart or lung problems.
How Do I Know It's Costochondritis?
Your doctor will press on your chest and if this reproduces your pain exactly, it's likely costochondritis. They may do an ECG and blood tests just to be sure it's not your heart.
How is it Treated?
- Reassurance: Knowing it's not your heart often helps!
- Anti-inflammatory painkillers: Ibuprofen or naproxen for 1-2 weeks
- Heat or ice packs: Applied to the sore area
- Avoid aggravating activities: Until it settles
How Long Does it Last?
Most people feel better within 1-2 weeks. Sometimes it takes a few months. It may come back occasionally but this is not dangerous.
When to Seek Help
See a doctor urgently if you have:
- Crushing chest pain, especially with exertion
- Pain spreading to arm, jaw, or back
- Shortness of breath
- Feeling faint or sweaty with chest pain
- Fever
Primary Guidelines
- NICE Clinical Knowledge Summaries. Chest Pain. cks.nice.org.uk
- ESC Guidelines. Management of Acute Coronary Syndromes. European Heart Journal. 2023.
Key Studies
- Proulx AM, Zryd TW. Costochondritis: diagnosis and treatment. Am Fam Physician. 2009;80(6):617-620. PMID: 19817327
- Disla E, et al. Costochondritis: a prospective analysis in an emergency department setting. Arch Intern Med. 1994;154(21):2466-2469. PMID: 7979843