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Infectious Diseases
EMERGENCY

Dog & Human Bites

High EvidenceUpdated: 2025-12-24

On This Page

Red Flags

  • Infection (Pasteurella, Eikenella, Capnocytophaga)
  • Tendon / Nerve / Joint Involvement
  • Fight Bite (Clenched Fist Injury over MCP)
  • Immunocompromised or Asplenic Patient
  • Rabies Risk (Unvaccinated Animal)
Overview

Dog & Human Bites

1. Topic Overview (Clinical Overview)

Summary

Mammalian bites (Dog, Cat, Human) are common injuries with significant infection risk due to inoculation of oral flora deep into tissues. Dog bites are most common; Cat bites are small punctures but highly prone to infection; Human bites (especially the "Fight Bite" – Clenched fist injury over MCP joint) carry the worst prognosis due to joint penetration. Key organisms include Pasteurella multocida (Dogs/Cats), Capnocytophaga canimorsus (Dogs – Especially dangerous in Asplenic/Immunocompromised), and Eikenella corrodens (Human bites). Management includes thorough wound irrigation, appropriate antibiotic prophylaxis (Co-Amoxiclav is first-line), Tetanus prophylaxis, assessment for Rabies risk, and careful consideration of wound closure (Facial bites usually closed; Hand/puncture wounds often left open).

Key Facts

  • Dog Bites: Most common. Crush injuries. Pasteurella. Capnocytophaga (Asplenic).
  • Cat Bites: Deep punctures. High infection rate (30-50%). Pasteurella (Fast onset).
  • Human Bites: "Fight Bite" = Clenched fist injury. Eikenella corrodens. High complication rate.
  • Antibiotic: Co-Amoxiclav (Covers Pasteurella, Staph, Strep, Eikenella, Anaerobes).
  • Closure: Facial bites – Close (Good blood supply). Hand/Puncture – Leave open or delayed closure.
  • Tetanus: Booster if >10 years (or >5 years if dirty wound).
  • Rabies: Assess risk (Animal source, Country, Vaccination status).

Clinical Pearls

"Fight Bite = Septic Arthritis Until Proven Otherwise": A wound over MCP in a clenched fist position likely penetrated the joint capsule. Treat aggressively.

"Cat Bites Infect Fast": Small punctures inoculate bacteria deep. Infection develops within 24 hours.

"Capnocytophaga in Asplenic Patients = Fulminant Sepsis": Dog bites in asplenic patients can cause rapid, fatal septicaemia.

"Co-Amoxiclav Covers Everything": First-line antibiotic for mammalian bites.

Why This Matters Clinically

Bites cause significant morbidity. Early recognition of high-risk wounds (Cat bites, Human fight bites, Immunocompromised host) and prompt antibiotic therapy prevent serious complications.


2. Epidemiology

Incidence

  • Dog Bites: ~60-90% of mammalian bites. ~250,000 A&E attendances/year (UK).
  • Cat Bites: ~10-15%. Higher infection rate than dogs.
  • Human Bites: ~3-5%. High complication rate.

Risk Factors for Infection

FactorNotes
Cat BitesPuncture wounds. Deep inoculation.
Human BitesEikenella. Joint penetration.
Hand BitesPoor blood supply. Tendon sheaths. Joint capsules.
Delayed Presentation (>2 hours)
ImmunocompromisedDiabetes, Steroids, Asplenia, HIV.
Puncture WoundsCannot be irrigated.
Crush InjuriesDevitalized tissue.

3. Microbiology

Organisms by Bite Type

BiteKey Organisms
DogPasteurella multocida, Pasteurella canis, Capnocytophaga canimorsus, Staphylococcus, Streptococcus, Anaerobes.
CatPasteurella multocida (Most common, Rapid infection), Bartonella henselae (Cat Scratch Disease).
HumanEikenella corrodens (Fastidious, Aggressive), Staphylococcus aureus, Streptococcus, Anaerobes, Viridans Streptococci. Sometimes Fusobacterium, Prevotella.

Special Organisms

OrganismNotes
Pasteurella multocidaFast-growing. Cellulitis within 24 hours. Purulent discharge.
Eikenella corrodens"Corrodes" agar. Aggressive. Associated with human bite/Fight Bite.
Capnocytophaga canimorsusDog/Cat saliva. Fulminant sepsis in Asplenic, Immunocompromised. DIC, Purpura Fulminans. High mortality.
Bartonella henselaeCat Scratch Disease. Lymphadenopathy.

4. Clinical Presentation

Wound Types

TypeNotes
PunctureCat bites. Small entry. Deep inoculation.
LacerationDog bites. Tearing.
Crush InjuryDog bites. Devitalized tissue.
AvulsionTissue loss. Dog bites (Especially children).

Signs of Infection

SignNotes
Redness (Erythema)Spreading.
Swelling
Warmth
Purulent DischargeYellow/Green pus.
PainIncreasing.
LymphangitisRed streaking.
Systemic SignsFever. Malaise. (Sepsis).

High-Risk Wounds

WoundRisk
Cat Bite (Any)High infection rate.
Hand BiteJoint/Tendon involvement.
Fight Bite (Clenched Fist)MCP joint penetration. Septic arthritis.
Puncture WoundsCannot irrigate.
Delayed Presentation (>2-24 hours)Already infected.
Immunocompromised PatientDiabetes, Cirrhosis, Asplenia, Steroids.

"Fight Bite" (Clenched Fist Injury)

FeatureNotes
MechanismPunch to teeth. Wound over MCP (Dorsal).
RiskTooth penetrates joint capsule -> Septic arthritis.
PresentationWound appears minor. May present late with established infection.
Always X-RayTooth fragment?
ManagementAggressive. Washout in theatre. IV Antibiotics. Often requires exploration.

5. Investigations
InvestigationPurpose
X-RayTooth fragments (Fight Bite). Fractures. Foreign body. Gas (Infection).
Wound Swab / Culture (If Infected)Identify organism + Sensitivities. Request Pasteurella/Eikenella.
Bloods (If Systemic)FBC, CRP, U&E. Blood cultures if septic.

6. Management

Principles

  1. History: Bite type (Dog, Cat, Human, Wild). Time since injury. Tetanus status. Allergies.
  2. Examination: Wound type. Depth. Neurovascular status. Tendon function. Joint involvement.
  3. Wound Care: Copious irrigation. Debride necrotic tissue.
  4. Antibiotics: Prophylaxis and/or Treatment.
  5. Tetanus Prophylaxis.
  6. Rabies Assessment.
  7. Wound Closure Decision.
  8. Referral if Indicated.

Wound Irrigation

  • Copious Normal Saline (Or Tap Water).
  • High Pressure (20-50ml syringe + Needle/Cannula).
  • Aim for at least 250-500ml for significant wounds.
  • Remove foreign material.

Antibiotic Therapy

First-Line: Co-Amoxiclav

DrugDoseDurationNotes
Co-Amoxiclav625mg TDS (Adults).5-7 days (Prophylaxis). 7-10 days (Treatment).Covers Pasteurella, Eikenella, Staph, Strep, Anaerobes.

If Penicillin Allergic

DrugDoseNotes
Doxycycline100mg BD+ Metronidazole 400mg TDS.
Or Clarithromycin500mg BD+ Metronidazole 400mg TDS.

Macrolides alone do NOT cover Pasteurella well.

Severe Infection / Sepsis

DrugRouteNotes
IV Co-Amoxiclav1.2g TDS
Or IV Piperacillin-TazobactamBroad cover.
Or MeropenemIf very severe/resistant.

Tetanus Prophylaxis

Vaccination HistoryTetanus-Prone Wound (Bites)
Fully Vaccinated (5 doses), Last dose <10 yearsNo booster needed.
Fully Vaccinated, Last dose >0 yearsBooster Td.
Not Fully Vaccinated / UnknownTd vaccine + Tetanus Immunoglobulin (If dirty/high-risk).

Rabies Assessment

QuestionNotes
Animal TypeDog, Cat, Bat, Wild animal?
Animal StatusKnown/Observable vs. Stray/Unknown? Vaccinated?
Country/RegionUK = Rabies-free (Low risk). Endemic regions = High risk.
Wound TypeLicks on broken skin. Bites. Scratches.
Pre-Exposure VaccinationPrevious rabies vaccination?

If risk identified: Post-Exposure Prophylaxis (PEP) = Rabies vaccine +/- Rabies Immunoglobulin. Consult PHE/UKHSA.

Wound Closure

Location / TypeClosure
FacePrimary closure (Good blood supply. Cosmetic importance).
ScalpUsually close.
Hand / Puncture Wounds / Cat BitesLeave open or Delayed Primary Closure (DPC).
Infected WoundsLeave open. Dress. Review.
Large WoundsMay require surgical exploration + Delayed closure.

Loose sutures if closing. Pack if leaving open. Follow-up essential.

Indications for Admission / Surgical Referral

IndicationAction
Fight Bite (Over MCP)Admit. IV Antibiotics. Theatre washout.
Tendon / Nerve / Joint InjuryHand Surgery / Plastic Surgery.
Severe Infection / AbscessAdmit. IV Antibiotics. Incision & Drainage.
Sepsis / ImmunocompromisedAdmit. Blood Cultures. IV Antibiotics.
Complex Wounds / Tissue LossPlastics.

7. Complications
ComplicationNotes
CellulitisCommon.
AbscessRequires drainage.
Septic ArthritisFight Bite. Cat bite to hand. Emergency.
OsteomyelitisDeep infection. X-Ray/MRI.
TenosynovitisHand bites. Kanavel's signs.
Sepsis / SepticaemiaCapnocytophaga (Asplenic). Pasteurella. Streptococcus.
Nerve InjuryPrimary or Secondary to infection.
Tendon Damage
RabiesIf applicable. Fatal if develops.
Scar / Cosmetic Deformity

8. Special Populations

Asplenic / Hyposplenic Patients

RiskNotes
Capnocytophaga canimorsusFulminant sepsis. DIC. Purpura fulminans.
ManagementVery low threshold for prophylactic antibiotics. Aggressive treatment.

Immunocompromised (Diabetes, Cirrhosis, Steroids, HIV)

  • Higher infection risk.
  • Lower threshold for antibiotics.

9. Evidence & Guidelines

Key Guidelines

GuidelineOrganisationNotes
NICE CKS – Bites (Human and Animal)NICEUK primary care guidance.
PHE Rabies GuidelinesUKHSA/PHEPost-Exposure Prophylaxis.

10. Exam Scenarios

Scenario 1:

  • Stem: A man punched another person in the mouth. He presents with a wound over his right 4th MCP joint. What is the diagnosis and management?
  • Answer: Fight Bite (Clenched Fist Injury). High risk of septic arthritis. X-Ray (Tooth fragment). Admit. IV Co-Amoxiclav. Washout in theatre.

Scenario 2:

  • Stem: A woman is bitten on the hand by a cat. 12 hours later, she has swelling, redness, and purulent discharge. What organism is most likely?
  • Answer: Pasteurella multocida (Rapid onset cellulitis from cat bite).

Scenario 3:

  • Stem: What antibiotic is first-line for mammalian bite wounds?
  • Answer: Co-Amoxiclav (Covers Pasteurella, Eikenella, Staph, Strep, Anaerobes).

11. Triage: When to Refer
ScenarioUrgencyAction
Minor Bite, No Infection RiskRoutineGP. Prophylactic antibiotics. Tetanus.
Infected Bite (Cellulitis)UrgentA&E / Urgent Review. Oral/IV Antibiotics.
Fight Bite / Hand BiteUrgentA&E. Hand Surgery referral. Theatre washout.
Tendon / Nerve / Joint InjuryUrgentHand Surgery / Plastics.
Sepsis / Severe InfectionEmergencyAdmit. IV Antibiotics. Blood Cultures.
Rabies Risk (Travel History)UrgentPHE/UKHSA. PEP.

12. Patient/Layperson Explanation

What should I do if I'm bitten?

  1. Clean the wound: Wash thoroughly under running water for at least 5 minutes.
  2. Seek medical attention: Especially for cat bites, hand bites, or large wounds.
  3. Antibiotics: You may need a course to prevent infection.
  4. Tetanus: Make sure your vaccinations are up to date.

When should I worry?

  • Wound getting redder, more swollen, or more painful.
  • Pus or discharge.
  • Fever or feeling unwell. Go back to the doctor or A&E if this happens.

Key Counselling Points

  1. Complete Antibiotic Course: "Finish all the antibiotics even if it looks better."
  2. Watch for Worsening Signs: "Come back if it gets redder, more swollen, or you feel unwell."
  3. Elevate Hand: "Keep your hand raised to reduce swelling."

14. Quality Markers: Audit Standards
StandardTarget
Wound irrigation performed100%
Tetanus status assessed100%
Antibiotic prophylaxis given for high-risk bites>5%
Fight Bite referred to Hand Surgery100%
Rabies risk assessed for travel/animal bite100%

15. Historical Context
  • Pasteurella first described late 19th Century. Named for Louis Pasteur.
  • Capnocytophaga Sepsis: Increasingly recognised from 1970s. High mortality in asplenic patients.

16. References
  1. NICE CKS. Bites – Human and Animal. cks.nice.org.uk
  2. UKHSA. Rabies: PHE Guidelines on Post-Exposure Prophylaxis. gov.uk

Last Reviewed: 2025-12-24 | MedVellum Editorial Team


Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. If you have been bitten, seek medical attention.

Last updated: 2025-12-24

At a Glance

EvidenceHigh
Last Updated2025-12-24
Emergency Protocol

Red Flags

  • Infection (Pasteurella, Eikenella, Capnocytophaga)
  • Tendon / Nerve / Joint Involvement
  • Fight Bite (Clenched Fist Injury over MCP)
  • Immunocompromised or Asplenic Patient
  • Rabies Risk (Unvaccinated Animal)

Clinical Pearls

  • **"Fight Bite = Septic Arthritis Until Proven Otherwise"**: A wound over MCP in a clenched fist position likely penetrated the joint capsule. Treat aggressively.
  • **"Cat Bites Infect Fast"**: Small punctures inoculate bacteria deep. Infection develops within 24 hours.
  • **"Capnocytophaga in Asplenic Patients = Fulminant Sepsis"**: Dog bites in asplenic patients can cause rapid, fatal septicaemia.
  • **"Co-Amoxiclav Covers Everything"**: First-line antibiotic for mammalian bites.
  • **Medical Disclaimer**: MedVellum content is for educational purposes and clinical reference. If you have been bitten, seek medical attention.

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines