Extradural Haematoma (Epidural Haematoma)
Summary
Extradural haematoma (EDH) is bleeding between the skull and dura mater, typically from arterial injury (middle meningeal artery) following temporal bone fracture. It is a neurosurgical emergency. The classic presentation is a "lucid interval" - initial loss of consciousness, apparent recovery, then rapid deterioration due to expanding haematoma and brain herniation. CT shows a characteristic biconvex (lens-shaped) hyperdensity limited by cranial sutures. Emergency craniotomy and haematoma evacuation is life-saving. Mortality is 5-10% with prompt surgery but approaches 90% if untreated or delayed.
Key Facts
- Cause: Middle meningeal artery rupture (85%); Dural venous sinuses (15%)
- Mechanism: Usually head trauma with temporal bone fracture
- Classic Sign: Lucid interval (seen in 20-50%)
- CT Appearance: Biconvex (lens-shaped), hyperdense, respects suture lines
- Treatment: Emergency craniotomy and evacuation
- Mortality: 5-10% with surgery; 90% without
Clinical Pearls
"Lucid Interval = Impending Disaster": A patient who was briefly unconscious, wokes up, then deteriorates is classic EDH. Act immediately.
"Lens-Shaped = Extradural": EDH is biconvex (lens) because dura is stripped off skull. SDH is crescent-shaped as blood spreads freely in subdural space.
"Respect the Sutures": EDH is limited by suture lines (dura firmly attached). If blood crosses sutures, think subdural or other pathology.
"Pupil on the Side of the Lesion": A fixed, dilated pupil is ipsilateral to the haematoma (uncal herniation compresses CN III).
Incidence
- 1-4% of head injury admissions
- Rare without history of trauma
Demographics
- Peak age: 20-40 years (active young adults)
- M:F = 4:1
- Rare in:
- Infants (dura tightly adherent)
- Elderly (dura becomes attached to skull with age)
Risk Factors
- Head trauma (especially temporal/parietal impact)
- Skull fracture (present in 75-95%)
- High-velocity injuries
- Assaults, falls, RTAs, sports injuries
- Anticoagulation (more rapid expansion)
Anatomy
- Dura mater normally adherent to inner skull table
- Middle meningeal artery runs in groove of temporal bone
- Dural venous sinuses (particularly at vertex)
Mechanism
┌──────────────────────────────────────────────────────────┐
│ PATHOPHYSIOLOGY OF EDH │
├──────────────────────────────────────────────────────────┤
│ │
│ 1. HEAD TRAUMA │
│ - Impact to temporal/parietal region │
│ - Deformity of skull │
│ │
│ 2. SKULL FRACTURE (75-95%) │
│ - Linear fracture through temporal bone │
│ - Tears middle meningeal artery │
│ │
│ 3. ARTERIAL BLEEDING (HIGH PRESSURE) │
│ - Blood accumulates between skull and dura │
│ - Dura progressively stripped from skull │
│ - Biconvex shape forms │
│ │
│ 4. MASS EFFECT │
│ - Raised ICP │
│ - Midline shift │
│ - Uncal herniation → CN III compression │
│ - Brainstem compression → Cushing response → Death │
│ │
└──────────────────────────────────────────────────────────┘
Why the "Lucid Interval"?
- Initial concussion → Loss of consciousness
- Recovery as concussion resolves
- Then deterioration as haematoma expands (takes 1-6 hours)
- Not always present (only 20-50% of cases)
Comparison: EDH vs SDH
| Feature | EDH | SDH |
|---|---|---|
| Source | Arterial (MMA) | Venous (bridging veins) |
| Shape | Biconvex (lens) | Crescent |
| Crosses sutures | No | Yes |
| Speed | Rapid | Variable (can be chronic) |
| Lucid interval | Classic (20-50%) | Rare |
| Skull fracture | 75-95% | Often absent |
Classic Presentation (Lucid Interval)
- Head injury with loss of consciousness
- Recovery to near-normal (lucid interval - minutes to hours)
- Deterioration: Headache, confusion, decreased GCS
- Coma, pupil dilation, posturing
- Death (if untreated)
Symptoms
| Feature | Notes |
|---|---|
| Headache | Progressively worsening |
| Vomiting | Raised ICP |
| Confusion | Evolving to obtundation |
| Seizures | May occur |
| Focal deficit | Contralateral hemiparesis |
Signs of Raised ICP
Signs of Uncal Herniation
Primary Survey
- ABCDE approach
- C-spine immobilisation
- GCS (document trend)
Neurological Examination
| Assessment | Significance |
|---|---|
| GCS | Trend most important |
| Pupils | Size, reactivity, asymmetry |
| Motor response | Lateralising signs, posturing |
| Cranial nerves | Especially III (pupil) and VI |
| Skull examination | Palpable step, haematoma, CSF leak |
Warning Signs Requiring Immediate Action
- GCS drop ≥2 points
- New pupil asymmetry
- New focal neurological deficit
- Posturing
CT Head (Gold Standard)
- Urgent, non-contrast CT
- Classic findings:
- Biconvex (lens-shaped) hyperdensity
- Adjacent to skull
- Limited by suture lines
- May see skull fracture
- Midline shift
- Effacement of ventricles
CT Findings Indicating Surgery
| Finding | Threshold |
|---|---|
| Volume | >0mL |
| Thickness | >5mm |
| Midline shift | >mm |
| GCS | ≤8 or deteriorating |
Other Investigations
- Full trauma workup (CT C-spine, chest, pelvis if indicated)
- Coagulation profile
- Group and screen
- Baseline bloods
Pre-Hospital / ED Stabilisation
┌──────────────────────────────────────────────────────────┐
│ IMMEDIATE MANAGEMENT OF EDH │
├──────────────────────────────────────────────────────────┤
│ │
│ STABILISE: │
│ • ABCDE approach │
│ • Intubate if GCS ≤8 │
│ • Maintain: SBP >90, SpO2 >90%, normocapnia │
│ • C-spine immobilisation │
│ │
│ REDUCE ICP (IF SIGNS OF HERNIATION): │
│ • Head up 30 degrees │
│ • Mannitol 0.5-1g/kg IV OR Hypertonic saline │
│ • Hyperventilate briefly (target PaCO2 30-35) │
│ │
│ URGENT CT HEAD │
│ │
│ NEUROSURGERY CONSULTATION IMMEDIATELY │
│ │
└──────────────────────────────────────────────────────────┘
Surgical Management
Craniotomy and Evacuation
- Standard treatment for significant EDH
- Burr hole may be life-saving temporising measure
- Definitive: Craniotomy, haematoma evacuation, haemostasis of MMA
Indications for Surgery
- Volume >30mL
- Thickness >15mm
- Midline shift >5mm
- GCS ≤8 or deteriorating GCS
- Focal neurological deficit
Conservative Management (Selected Cases Only)
- Small EDH (<30mL) AND
- No midline shift AND
- GCS 15 AND
- No neurological deficit
- REQUIRES: Close observation, serial CT, ideally in neurosurgical unit
Of EDH
- Brain herniation (uncal, central)
- Secondary brain injury
- Seizures
- Death
After Surgery
- Rebleeding
- Infection (wound, meningitis)
- Cerebral oedema
- Post-traumatic epilepsy
- Residual neurological deficit
Mortality
| Scenario | Mortality |
|---|---|
| Prompt surgery | 5-10% |
| Delayed surgery | 30-50% |
| Untreated | 90%+ |
Functional Outcomes
- With early surgery: 50-80% make good recovery
- Pre-operative GCS is strongest predictor
- GCS 3: Very poor prognosis even with surgery
- GCS 9-15: Good prognosis with early intervention
Prognostic Factors
| Good | Poor |
|---|---|
| Young age | Elderly |
| High GCS at surgery | Low GCS |
| No focal deficit | Pupil abnormalities |
| Short time to surgery | Delayed surgery |
| No other intracranial injury | Associated contusions |
Key Guidelines
- NICE Head Injury Guidelines (CG176, 2014; updated 2017)
- Brain Trauma Foundation Guidelines (2016)
- SBNS Standards of Care for Severe Head Injury
Key Evidence
Surgical vs Conservative
- Non-randomised data strongly supports surgery
- Mortality without surgery approaches 90%
Timing of Surgery
- Earlier surgery = Better outcomes
- "Golden hour" concept applies
- Each 30-minute delay increases mortality
What is an Extradural Haematoma?
An extradural haematoma (also called epidural haematoma) is bleeding between the skull and the outer covering of the brain (dura). It's usually caused by a head injury that tears a blood vessel, typically an artery.
Why is it Dangerous?
The bleeding creates a blood clot that presses on the brain. Because the skull is rigid, this pressure can push the brain downwards (herniation), which is life-threatening.
What Are the Warning Signs?
After a head injury, watch for:
- Severe or worsening headache
- Confusion or unusual behaviour
- Vomiting
- Drowsiness or difficulty walking
- One pupil larger than the other
- Weakness in arm or leg
The "Lucid Interval"
Sometimes a person with this injury seems to recover briefly before getting worse. This is called a lucid interval and is a classic warning sign.
How is it Treated?
Emergency surgery is usually needed to remove the blood clot and stop the bleeding. With quick treatment, most people make a good recovery.
When to Seek Help
Call 999 immediately if someone:
- Has had a head injury and becomes increasingly drowsy
- Is confused or their behaviour changes after a head injury
- Has a seizure after a head injury
- Has different-sized pupils
Primary Guidelines
- NICE. Head Injury: Assessment and Early Management (CG176). 2017. nice.org.uk/guidance/cg176
- Brain Trauma Foundation. Guidelines for the Management of Severe Traumatic Brain Injury. 4th edition. 2016.
Key Studies
- Bullock MR, et al. Surgical management of acute epidural hematomas. Neurosurgery. 2006;58(3 Suppl):S7-15. PMID: 16540746