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Orthopaedics
Trauma
EMERGENCY

Femoral Shaft Fractures

High EvidenceUpdated: 2025-12-26

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Red Flags

  • Hypoxia + Confusion + Petechiae -> Fat Embolism Syndrome (FES)
  • Ipsilateral Neck Fracture -> Missed in 10% (Requires CT)
  • Open Fracture -> Antibiotics + Debridement <6h
  • Compartment Syndrome -> Rare in thigh but lethal
Overview

Femoral Shaft Fractures

1. Clinical Overview

Summary

The femur is the strongest bone in the body. Fractures typically require high-energy trauma (MVC, pedestrian struck) in the young, or low-energy falls in the elderly (spiral fractures). It is a life-threatening injury due to hemorrhage (1-2 Litres into the thigh) and the risk of Fat Embolism Syndrome. Treatment is universally surgical (Intramedullary Nailing). A dreaded complication is the missed Ipsilateral Femoral Neck Fracture, which occurs in 5-10% of high-energy shaft fractures and must be actively sought (CT Scan). [1,2,3]

Key Facts

  • Hemorrhage Class: A single closed femur fracture can cause Class II or III shock (1500ml blood loss).
  • Fat Embolism Syndrome (FES): Marrow fat enters the venous system. Triad: Hypoxia, Confusion, Petechial Rash. Early stabilization (Nailing) reduces this risk.
  • The "Floating Knee": Fracture of the femoral shaft AND ipsilateral tibial shaft. The knee is disconnected from the skeleton. High rate of ligamentous injury and vascular damage.

Clinical Pearls

"Fix the Neck First": If there is an ipsilateral neck fracture and shaft fracture, the neck takes priority. A missed neck fracture leads to AVN and definitive disability. Fix the neck with screws, then nail the shaft (Retrograde or Cephalomedullary).

"Traction Splint": The Thomas Splint or Kendrick Traction Device is critical in pre-hospital care. It reduces pain, reduces bleeding (tamponade), and aligns the leg. Contraindication: Suspected Ipsilateral Neck Fracture (traction may pull the head off).

"The Third Fragment": In high energy comminuted fractures, look for a large butterfly fragment. If it is on the medial side, stability is compromised.


2. Epidemiology

Demographics

  • Bimodal:
    • Young Males (<40): High velocity trauma. Transverse/Comminuted patterns.
    • Elderly Females (>70): Low energy falls. Spiral patterns (osteoporosis) or Periprosthetic (around a hip/knee replacement).
  • Incidence: 10 per 100,000.

Associated Injuries

  • Ipsilateral Neck Fracture: 10%.
  • Knee Ligament Injury: 20-30% (ACL/PCL/Posterolateral corner) - often missed as knee exam is difficult.
  • Visceral Injury: Chest/Abdo trauma common in high energy mechanism.

3. Pathophysiology

Anatomy

  • Deforming Forces:
    • Proximal Fragment: Flexed (Psoas), Abducted (Gluteus medius), Externally Rotated (Short rotators).
    • Distal Fragment: Pulled Up (Quadriceps/Hamstrings), Adducted (Adductors), Extended (Gastrocnemius).
  • Result: The classic "Short and Deformed" thigh.

Classification (Winquist and Hansen)

Based on the degree of comminution (fragmentation). Predicts stability of nailing.

  • Type 0: No comminution (Simple fracture). Stable.
  • Type I: Small butterfly fragment. <25% of cortex. Stable.
  • Type II: Butterfly fragment <50% of cortex. Stable.
  • Type III: Butterfly fragment >50% of cortex. Unstable (Nail acts as load-bearing, not load-sharing).
  • Type IV: Segmental comminution. No contact between proximal and distal cortices. Unstable.

Classification (AO/OTA)

  • 32-A: Simple (Spiral, Oblique, Transverse).
  • 32-B: Wedge (Butterfly).
  • 32-C: Complex (Segmental).

4. Clinical Presentation

Symptoms

Signs


Pain
Screaming agony.
Deformity
Thigh looks swollen and shortened.
5. Investigations

Imaging

  • X-Ray Full Length Femur (AP & Lat): Include Hip and Knee joints.
  • X-Ray Pelvis: Rule out pelvic ring injury.
  • CT Scan: Usually part of Trauma Pan-Scan.
    • Mandatory: Dedicated CT Hip if high energy mechanism to rule out Neck Fracture.

Lab Tests

  • Group and Save: 2-4 Units.
  • Coagulation: TEG/ROTEM in major trauma.
  • Lactate: Monitor resuscitation.

6. Management Algorithm
              FEMORAL SHAFT FRACTURE
                       ↓
              TRAUMA RESUSCITATION
             (Splint / IV Access / CT)
                       ↓
              STABLE? (Physiologically)
              ┌───────┴───────┐
             YES             NO
          (EUC)        (Damage Control)
             ↓                ↓
       DEFINITIVE FIXATION   EXTERNAL FIXATION
        (Within 24 hours)    (Stop bleeding)
             ↓                ↓
       FRACTURE LOCATION?    ICU -> CONVERT
      ┌──────┴───────┐       TO NAIL (Day 5)
   PROXIMAL/MID    DISTAL
      ↓              ↓
  ANTEGRADE NAIL  RETROGRADE NAIL
      OR             OR
  PLATE (If neck) PLATE (If intra-articular)

7. Management Protocols

1. Damage Control Orthopaedics (DCO)

  • Indication: Patient in extremis (pH <7.2, Lactate >4, Coagulopathy, Hypothermia). This is the "Triad of Death". Long surgery (Nailing) will kill them via inflammatory "Second Hit".
  • Action: External Fixator (<30 mins). ICU.
  • Conversion: Convert ExFix to Nail when stable (usually Day 4-7).

2. Intramedullary Nail (Gold Standard)

  • Antegrade Nail: Entered via Greater Trochanter (Piriformis Fossa).
    • Pros: Gold standard. 98% union rate.
    • Cons: Hip abductor damage (limp).
  • Retrograde Nail: Entered via Knee (Intercondylar notch).
    • Pros: Good for distal fractures, obesity, bilateral fractures (no need to reposition patient).
    • Cons: Opens the knee joint (septic arthritis risk).

3. Open Reduction Internal Fixation (Plating)

  • Indication:
    • Distal/Proximal fractures extending into joint.
    • vascular injury (needs repair first).
    • paediatric patients (physeal sparing).
  • Cons: Huge incision, strips periosteum, slower healing, higher infection rate.

8. Complications

Early

  • Fat Embolism Syndrome (FES):
    • Mechanism: Marrow fat forced into venous circulation.
    • Gurd's Criteria: Major (Petechial rash, Respiratory insufficiency, Cerebral involvement). Minor (Tachycardia, Fever, retinal changes).
    • Treatment: Supportive (Oxygen/Ventilation). Fix fracture early (<24h).
  • Hemorrhage.
  • Nerve Injury: Pudendal nerve neurapraxia (from perineal post during traction table nailing).

Late

  • Non-Union: 1-2%. Usually due to smoking or instability. Treatment: Exchange nailing (Larger nail).
  • Malunion: Rotational deformity is main risk. (Toes point in/out).
  • Heterotopic Ossification: Bone formation at nail entry point.

9. Evidence & Guidelines

The SPRINT Trial (2008)

  • Question: Reamed vs Unreamed Nails?
  • Result: Reaming (drilling the canal) stimulates blood flow/healing but theoretically pushes fat emboli. Trial showed Reaming is safe and leads to lower non-union rates.

BOAST 4 Guidelines (Open Fractures)

  • Antibiotics <1h.
  • Debridement immediately (if highly contaminated/vascular) or <24h.
  • Coverage (Plastic surgery) <72h.

10. Patient Explanation

The Injury

You have snapped the thigh bone. It is the strongest bone in your body. It takes a huge force to do this.

The Operation

We put a "Rod" (titanium nail) down the hollow centre of the bone. This acts as an internal splint. It shares the load so you can walk on it almost immediately.

Recovery

  • Walking: You can walk tomorrow with crutches.
  • Driving: 6-8 weeks (when you can emergency stop).
  • Healing: 3-6 months for full consolidation.

11. References
  1. Winquist RA, Hansen ST. Comminuted Fractures of the Femoral Shaft. Clin Orthop. 1980.
  2. Bhandari M, et al. (SPRINT Investigators). Randomized Trial of Reamed and Unreamed Intramedullary Nailing of Tibial Shaft Fractures. J Bone Joint Surg Am. 2008. (Extrapolated).
  3. Gurd AR. Fat Embolism: an aid to diagnosis. J Bone Joint Surg Br. 1970.
12. Examination Focus (Viva Vault)

Q1: What are Gurd's Criteria for Fat Embolism Syndrome? A: Diagnosis requires 1 Major + 4 Minor.

  • Major: (1) Petechial Rash (Axilla/Conjunctiva - pathognomonic). (2) Respiratory Insufficiency (Hypoxia). (3) Cerebral Involvement (Confusion/Coma).
  • Minor: Tachycardia, Pyrexia, Retinal changes, Jaundice, Renal impairment.

Q2: How do you treat a femoral shaft fracture with an ipsilateral neck fracture? A: Priority to the Neck. The neck fracture threatens the hip joint (AVN). I would fix the neck first (usually with Cannulated Screws or a DHS) BEFORE nailing the shaft, to avoid displacing the neck during nail insertion. Alternatively, use a Reconstruction Nail (Cephalomedullary nail) which sends screws up into the neck through the nail, fixing both.

Q3: Define "Damage Control Orthopaedics". A: A strategy for physiolgically unstable polytrauma patients (Acidosis, Coagulopathy, Hypothermia). The goal is to minimize the "Second Hit" of surgery. We perform rapid, temporary stabilization (External Fixation) <30 mins, resuscitate in ICU, and return for definitive Nailing days later when the patient is stable (Day 5-7).

(End of Topic)

Last updated: 2025-12-26

At a Glance

EvidenceHigh
Last Updated2025-12-26
Emergency Protocol

Red Flags

  • Hypoxia + Confusion + Petechiae -> Fat Embolism Syndrome (FES)
  • Ipsilateral Neck Fracture -> Missed in 10% (Requires CT)
  • Open Fracture -> Antibiotics + Debridement &lt;6h
  • Compartment Syndrome -> Rare in thigh but lethal

Clinical Pearls

  • **"The Third Fragment"**: In high energy comminuted fractures, look for a large butterfly fragment. If it is on the medial side, stability is compromised.

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines