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Psychology

Health Anxiety (Illness Anxiety Disorder)

High EvidenceUpdated: 2025-12-25

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Red Flags

  • Suicidal Ideation
  • Severe Functional Impairment
  • Comorbid Depression
  • Substance Misuse
Overview

Health Anxiety (Illness Anxiety Disorder)

1. Clinical Overview

Summary

Health Anxiety, classified in DSM-5 as Illness Anxiety Disorder (IAD) or Somatic Symptom Disorder (SSD) depending on presentation, is a condition characterised by Preoccupation with Having or Acquiring a Serious, Undiagnosed Medical Illness despite minimal or no somatic symptoms and negative investigations. Patients experience Persistent Worry about their health, Engage in Excessive Health-Related Behaviours (Body checking, Reassurance-seeking, Frequent medical consultations, Internet searching) or Avoidant Behaviours (Avoiding doctors, Medical settings, Health information). The condition affects approximately 1-5% of the population and causes significant distress and functional impairment. Key differentials include Somatic Symptom Disorder (Where significant physical symptoms ARE present) and genuine medical conditions. Health anxiety is often Comorbid with Depression, Generalised Anxiety Disorder, OCD, and Panic Disorder. First-line treatment is Cognitive Behavioural Therapy (CBT), which has strong evidence. SSRIs are effective as adjunctive or standalone treatment, particularly when comorbid depression is present. The condition has a Chronic Course but can improve significantly with appropriate treatment. Management in primary care requires a balance of Validation, Limiting Unnecessary Investigations, and Active Psychological Treatment rather than simple reassurance. [1,2,3]

Key Facts

FactValue
DefinitionPreoccupation with having/Acquiring serious illness, Minimal/No symptoms
DSM-5 ClassificationsIllness Anxiety Disorder (IAD); Somatic Symptom Disorder (SSD)
ICD-11 Code6B23 (Hypochondriasis)
Prevalence (General)1-5%
Prevalence (Primary Care)3-8%
Prevalence (Medical Outpatients)4-10%
Peak AgeEarly-Middle adulthood (20-40)
SexEqual (Or slight female predominance)
CourseChronic, Waxing and waning
Key DistinctionIAD = Minimal symptoms; SSD = Significant symptoms
First-Line TreatmentCognitive Behavioural Therapy (CBT)
PharmacotherapySSRIs (Fluoxetine 20-60mg, Paroxetine 20-50mg)
CBT SessionsTypically 8-16 sessions
Treatment Response50-70% significant improvement with CBT
PrognosisChronic but treatable
Common Feared IllnessesCancer, Heart disease, Neurological disease
Key ComorbiditiesDepression (40-60%), GAD (30-50%), Panic (20-40%)
Healthcare Impact3-10x more GP visits than average
CyberchondriaExcessive internet health searching
SubtypesCare-seeking vs Care-avoidant

Clinical Pearls

"Reassurance Doesn't Work Long-Term": Brief relief followed by return of anxiety. Avoid reassurance-seeking cycles.

"IAD = Minimal Symptoms; SSD = Significant Symptoms": Key DSM-5 distinction – Know this for exams.

"Cyberchondria": Modern phenomenon – Excessive health-related internet searching worsens anxiety.

"High Users of Healthcare": Often significant healthcare utilisation without benefit, Costly.

"CBT is First-Line": Strong evidence base. SSRIs as adjunct or if comorbid depression.

"Avoid the Investigation Trap": Each normal test provides brief relief, Then anxiety returns, Cycle repeats.

"Validate, Don't Dismiss": Say "Your symptoms are real, But caused by anxiety" – NOT "There's nothing wrong."

"Schedule Appointments, Don't Go When Anxious": Reduces PRN attendance pattern.

"Safety Behaviours Maintain the Cycle": Body checking, Googling, Reassurance – All perpetuate.

"Screen for Depression": 40-60% comorbid, Worsens outcomes, Needs treating.

"Limit Investigations – One and Done": Agree in advance, Break the cycle.

"Cognitive Model is Key": Trigger → Misinterpretation → Anxiety → Safety behaviour → Cycle.

"Stepped Care": Self-help → Guided self-help → CBT → Specialist. Match intensity to severity.

"iCBT Works": Internet-based CBT is effective and accessible (Hedman 2014).

"Anxious Cluster Personality": Cluster C personality traits worsen prognosis.

"Prognosis is Good with Treatment": 50-70% improve significantly with CBT.

"Think About the Family": Partners often frustrated, Psychoeducation helps.

"Greeven 2007": Key RCT – CBT and Paroxetine both effective, CBT more durable.

Why This Matters Clinically

Health anxiety is extremely common in primary care and general medical settings, Often unrecognised and poorly managed. It leads to significant healthcare utilisation, Unnecessary investigations (With associated risks), Patient distress, And clinician frustration. Effective management requires understanding the condition as a psychological disorder requiring specific treatment rather than simply more investigations or reassurance. Liaison psychiatry and integrated psychological services are increasingly important. This condition is examined in both psychiatric and general medical contexts due to its prevalence and the need for appropriate management strategies.


2. Epidemiology

Key Principle

[!NOTE] Health anxiety is a common but under-recognised condition affecting 1-5% of the population. It leads to significant healthcare utilisation and costs. Recognition in primary care and general medical settings is essential for appropriate management.

Incidence & Prevalence

MeasureValueNotes
Prevalence (General Population)1-5%Depending on criteria used
Prevalence (Primary Care)3-8%Higher in healthcare settings
Prevalence (Medical Outpatients)4-10%Common in specialty clinics
Prevalence (Specialist Clinics)Up to 20%Cardiology, Neurology, Gastroenterology
Age of Onset20-40 yearsBut can occur at any age
CourseChronicWaxing and waning over years
Incidence Rate~1% per yearNew cases

Global Burden

RegionEstimated PrevalenceNotes
Worldwide1-5%Consistent across cultures
Western Europe3-5%Well-studied
North America3-5%Similar rates
Asia1-3%May present differently (Somatic focus)
Developing CountriesLimited dataMay be underdiagnosed

Demographics

FactorDetailsClinical Significance
AgePeak 20-40 yearsCan start in adolescence or later
SexEqual or slight female predominance
SocioeconomicAll levelsMay be overrepresented in higher SES
EducationAll levelsHigher education does not protect
Healthcare UseVery high3-10x general population visits
CostSignificantHigh healthcare utilisation costs

Healthcare Utilisation Impact

FactorImpact
GP Visits3-10x more than average
Specialist ReferralsFrequent, Often unnecessary
InvestigationsMultiple, Repeated, Often normal
A&E AttendanceMay be increased (Health crises)
Hospital AdmissionsMay occur for investigation
Healthcare CostsEstimated 2-5x higher than average
Lost ProductivityWork absences, Reduced function

Age-Specific Features

Age GroupPresentationNotes
AdolescenceMay focus on specific fears (Cancer, HIV)Often with anxiety/depression
Young Adults (20-35)Classic presentationPeak onset
Middle Age (35-55)Heart, Cancer fears predominantMay follow family illness
Older Adults (55+)Dementia, Cancer fearsMay overlap with genuine health concerns

Risk Factors - Detailed

Predisposing Factors:

FactorMechanism
Personal History of Serious IllnessEspecially childhood illness, Hospitalisation
Family History of Serious IllnessParental illness/Death, Especially in childhood
Traumatic Medical ExperiencesMisdiagnosis, Medical error, Iatrogenic harm
History of Abuse/TraumaPhysical, Sexual, Emotional (Somatisation)
Neuroticism (Personality Trait)High neuroticism predisposes to all anxiety
Anxious Attachment StyleInsecure attachment

Precipitating Factors:

FactorExample
Life EventsBereavement, Illness in loved one
Media ExposureHealth scares, Celebrity illness stories
Medical EncountersBeing told "We need to run tests"
Physical SymptomsAny unexplained symptom

Maintaining Factors:

FactorHow It Maintains
Reassurance-SeekingBrief relief, Then return of anxiety
Body CheckingIncreases focus on sensation
Internet Searching"Cyberchondria" – Confirms fears
AvoidancePrevents learning that fears unfounded
OverinvestigationMedical system inadvertently reinforces

Comorbidities - Detailed

ComorbidityPrevalenceRelationship
Major Depressive Disorder40-60%Common and bidirectional
Generalised Anxiety Disorder30-50%Overlapping worry patterns
Panic Disorder20-40%Somatic symptom overlap
OCD10-20%Health-related obsessions
Social Anxiety10-20%May avoid medical settings
PTSDVariableIf medical trauma
Personality Disorders10-30%Especially Cluster C (Anxious)
SomatisationOverlapContinuum with SSD

3. Pathophysiology

Cognitive Model (Central to Understanding and Treatment)

Step 1: Triggering Event

  • Internal Trigger: Normal bodily sensation (Heartbeat awareness, Muscle twitch, Minor pain)
  • External Trigger: Health information (News, Internet, Friend's illness)
  • Low Threshold: Heightened attention to body (Hypervigilance)

Step 2: Misinterpretation (Catastrophic Cognition)

  • Normal sensation misinterpreted as sign of serious illness
  • Cognitive distortions:
    • Catastrophising: "This headache must be brain cancer"
    • Probability Overestimation: "Heart symptoms = Heart attack is likely"
    • Confirmation Bias: Noticing confirmatory info, Ignoring reassurance
    • Emotional Reasoning: "I feel unwell, So I must BE unwell"

Step 3: Anxiety Response

  • Physiological: Sympathetic activation (Increased HR, Sweating, Tension, GI upset)
  • Emotional: Fear, Dread, Distress
  • Cognitive: Rumination, Worry, Cannot "switch off"
  • Physiological Symptoms Reinforce Belief: "I DO have symptoms!"

Step 4: Safety Behaviours

  • Reassurance-Seeking: Repeated GP visits, Investigations, "Dr Google"
  • Body Checking: Palpating lumps, Checking pulse, Examining skin
  • Avoidance: Avoiding medical settings OR avoiding health info
  • Short-Term Relief: Temporary reduction in anxiety (Negative reinforcement)
  • Long-Term Worsening: Does not address core cognitions; Reinforces cycle

Step 5: Maintenance of Cycle

  • Relief from reassurance is short-lived
  • New symptoms or triggers restart cycle
  • Hypervigilance maintained
  • No opportunity to learn that symptoms are benign
  • Condition becomes chronic

Neurobiological Factors

FactorFindings
Somatosensory AmplificationHeightened perception of bodily sensations
Amygdala HyperactivityThreat processing
Prefrontal CortexReduced top-down modulation of anxiety
Serotonergic SystemImplicated (Response to SSRIs)
Autonomic DysregulationIncreased sympathetic tone

Pathophysiology Diagram

Health Anxiety Management Algorithm


4. Clinical Presentation

Key Principle

[!NOTE] Health anxiety presents with:

  • Preoccupation with having a serious illness
  • Minimal or absent somatic symptoms (In IAD)
  • Excessive behaviours (Checking, Reassurance, Googling)
  • Impaired function (Work, Relationships, Quality of life) Despite these features, Always consider genuine medical conditions.

DSM-5 Diagnostic Criteria

Illness Anxiety Disorder (IAD):

CriterionDescription
APreoccupation with having or acquiring a serious illness
BSomatic symptoms are NOT present OR only mild
CHigh level of anxiety about health
DExcessive health-related behaviours (Checking, Reassurance) OR maladaptive avoidance
EDuration ≥6 months (Though specific illness feared may change)
FNot better explained by another mental disorder

Somatic Symptom Disorder (SSD):

CriterionDescription
AOne or more somatic symptoms that are distressing or disruptive
BExcessive thoughts, Feelings, Or behaviours related to somatic symptoms
CDuration ≥6 months (Though specific symptoms may vary)

Key Distinction: IAD vs SSD:

FeatureIADSSD
Somatic SymptomsMinimal or absentSignificant, Present
FocusFear of having illnessDistress about symptoms
Physical BasisLittle or noneSymptoms are real/present

Typical Presentation - Detailed

FeatureDescriptionClinical Significance
PreoccupationConstant worry about serious illnessOften Cancer, Heart, Neurological
Minimal SymptomsIn IAD – Little physical basisDistinguishes from SSD
Reassurance-SeekingMultiple GP visits, Specialists, TestsHigh healthcare use
Temporary ReliefReassured briefly, Then returnsCharacterisitc pattern
Body CheckingFrequent self-examinationSelf-palpation, Checking pulse
"Dr Google"Excessive internet searching"Cyberchondria"
Functional ImpairmentWork, Relationships, SocialSignificant distress
AvoidanceSome avoid medical settingsCare-avoidant subtype

Symptom Patterns

Physical Symptoms Often Complained Of (Despite Normal Findings):

SystemExamples
CardiovascularPalpitations, Chest discomfort
NeurologicalHeadaches, Tingling, Dizziness
GastrointestinalAbdominal discomfort, Bloating
MusculoskeletalLumps, Aches, Pains
GeneralFatigue, Feeling unwell

Note: In IAD these are minimal. In SSD they are prominent.

Cognitive Distortions in Health Anxiety

DistortionExample
Catastrophising"This headache MUST be a brain tumour"
Probability Overestimation"I'm definitely going to have a heart attack"
Confirmation BiasNotices symptoms that confirm fear, Ignores reassurance
Emotional Reasoning"I feel terrified, So I must be ill"
Selective AttentionHypervigilant to body sensations
All-or-Nothing Thinking"If tests aren't 100% certain, I could be ill"
Mind Reading"The doctor looked worried – They must think it's serious"

Common Feared Illnesses - Detailed

IllnessPrevalenceNotes
CancerMost commonBrain, Bowel, Lung, Breast (Women), Skin
Heart DiseaseVery commonMI, Arrhythmia, Sudden cardiac death
Neurological DiseaseCommonMS, Brain tumour, ALS, Dementia
HIV/STIsOften despite negative testing
DementiaEspecially in older patients
Rare DiseasesAfter media exposure
Whatever Was Last Searched"Cyberchondria" effect

Behavioural Subtypes

SubtypeDescriptionBehaviour
Care-Seeking TypeMost commonHigh healthcare utilisation, Frequent requests for tests
Care-Avoidant TypeLess commonAvoids medical settings, Health information

Severity Classification

SeverityFeaturesManagement Level
MildOccasional worry, Functions normallySelf-help, Watchful waiting
ModerateRegular preoccupation, Some functional impactCBT, Consider SSRI
SevereConstant worry, Significant impairmentCBT + SSRI, Specialist referral
Very SevereHousebound, Unable to work, Suicidal thoughtsUrgent specialist, Risk assessment

Red Flags (Require Assessment)

[!CAUTION] Red Flags in Health Anxiety:

  • Suicidal Ideation/Self-Harm: Distress can be severe
  • Severe Depression: Common comorbidity
  • Psychotic Features: Somatic delusions (Different diagnosis)
  • Substance Misuse: Self-medicating with alcohol, Benzodiazepines
  • Severe Functional Impairment: Unable to work, Housebound
  • Genuine Medical Condition: Must always consider and appropriately investigate

Differentiating Health Anxiety from Genuine Concern

Health AnxietyNormal Health Concern
Preoccupation constantWorry resolves with reassurance
Reassurance ineffectiveReassurance works
Multiple feared illnessesConcern about specific issue
Excessive behavioursAppropriate help-seeking
Disproportionate to riskProportionate

5. Clinical Examination

Key Principle

[!NOTE] Assessment of Health Anxiety requires:

  • Validating patient's distress (Not dismissing)
  • Thorough but focused history (Avoid reinforcing by over-examining)
  • Appropriate (Limited) physical examination
  • Exploring psychological factors (Cognitions, Behaviours)
  • Screening for comorbidities (Depression, Other anxiety)

Approach to Assessment

Key Principles:

  • Take symptoms seriously (Do not dismiss)
  • Complete thorough but focused history
  • Appropriate (Limited) physical examination
  • Avoid over-investigation
  • Explore psychological factors
  • Screen for depression and other anxiety disorders

Structured History Taking:

ComponentQuestionsWhat to Look For
Presenting Concern"What are you worried might be wrong?"Nature of feared illness
Symptom HistoryOnset, Duration, NatureMinimal symptoms in IAD
Health Beliefs"What do you think is causing this?"Catastrophic cognitions
Previous InvestigationsHow many? Results? Effect on anxiety?Multiple, Normal, Brief relief
Reassurance Pattern"After tests are normal, How long do you feel reassured?"Brief (Hours to days)
BehavioursBody checking, Internet searching, Doctor visitsExcessive
AvoidanceAvoiding medical settings OR health informationCare-avoidant subtype
Functional ImpactWork, Relationships, SocialSignificant impairment
Psychiatric HistoryDepression, Anxiety, OCDCommon comorbidities
Medical HistoryPersonal/Family serious illnessRisk factors
TriggersWhat started this worry?Life events, Media

Key Questions to Ask:

QuestionPurpose
"What do you fear the most?"Identify specific feared illness
"What would it mean for you if you had [feared illness]?"Explore underlying cognitions
"How often do you check your body?"Assess safety behaviours
"How often do you search symptoms online?"Cyberchondria
"How has this affected your daily life?"Functional impact
"Have you ever thought about harming yourself?"Risk assessment

Physical Examination:

  • Targeted, Appropriate examination based on presenting symptoms
  • Avoid repetitive examinations at every visit
  • Explain findings clearly
  • Do NOT examine repeatedly for reassurance

Mental State Examination - Detailed

ComponentTypical FindingsNotes
AppearanceOften normalMay be visibly anxious
BehaviourAnxious demeanourMay seek reassurance during consultation
SpeechNormal or pressuredWith health concerns
MoodAnxiousMay be low (Comorbid depression)
AffectAnxious, WorriedRelieved temporarily by reassurance
Thought ContentPreoccupied with health/illnessNOT delusional (Insight present)
Thought FormRuminationCircling back to health concerns
PerceptionsNormalNo hallucinations
CognitionNormalMay have difficulty concentrating
InsightOften partial"I know it might be anxiety, But..."
RiskAssess suicide/Self-harmMay be elevated in severe cases

Screening Tools

ToolItemsWhat It Measures
Whiteley Index14Health anxiety (Widely used)
Health Anxiety Inventory (HAI)18Health anxiety (Validated)
Illness Attitude Scales27Health anxiety
PHQ-99Depression (Screen for comorbidity)
GAD-77Generalised anxiety (Comorbidity)
AUDIT10Alcohol misuse

Formulating the Case

ComponentContent
PredisposingChildhood illness, Family history, Trauma, Neuroticism
PrecipitatingLife event, Media exposure, Symptom
PerpetuatingReassurance-seeking, Body checking, Cyberchondria, Avoidance
ProtectiveInsight, Supportive relationships, Engagement

Example Formulation:

"This is a 35-year-old woman presenting with health anxiety (Illness Anxiety Disorder), predisposed by a history of parental cancer, precipitated by noticing an abdominal discomfort, and perpetuated by daily body checking, Internet searching, and frequent GP consultations. Protective factors include partial insight and a supportive partner."


6. Investigations

Key Principle

Avoid the Investigation Trap: Repeated investigations reinforce the cycle. Each normal test provides brief relief, Then anxiety returns, Leading to requests for more tests.

Appropriate Investigation Approach

ApproachDescription
Initial AssessmentOne-off, Focused investigation of specific symptoms if clinically indicated
Agreed LimitExplicitly agree with patient: "We will do these tests once. If normal, We will not repeat."
Avoid RepetitionDo NOT repeat investigations for reassurance
Explain Rationale"Normal tests tell us your body is healthy. The problem is how you're feeling about your body."

When to Investigate

SituationAction
New SymptomsAppropriate clinical assessment
Red Flag SymptomsAlways investigate appropriately
Objective SignsInvestigate findings, Not fears
Significant ChangeGenuinely new or different symptom

Screening Tools (For Health Anxiety)

ToolDescription
Whiteley Index14-item self-report. Widely used.
Health Anxiety Inventory (HAI)18-item. Validated.
Illness Attitude Scales27-item.
PHQ-9Screen for depression (Comorbid)
GAD-7Screen for generalised anxiety

7. Management

Key Principle

[!IMPORTANT] Management of Health Anxiety requires:

  • Validation of distress (Not dismissal)
  • Limiting investigations (To break the cycle)
  • Active psychological treatment (CBT is first-line)
  • Scheduled follow-up (Not PRN)
  • Treating comorbidities (Depression, GAD)

Management Algorithm

Health Anxiety Management Algorithm

Communication and Therapeutic Relationship

Key Communication Strategies:

StrategyImplementationWhat to Say
Validate DistressAcknowledge suffering"I can see how distressing this is for you"
Avoid DismissalNever minimiseDo NOT say "There's nothing wrong"
Acknowledge RealitySymptoms are real"The symptoms are real; Let's understand them better"
ReframeName the problem"The problem is your health anxiety, Which is very treatable"
Limit ReassuranceExplain why"Reassurance feels good briefly, But it doesn't help long-term"
CollaboratePartnership"Let's work together on this"
ContinuitySame clinicianRegular scheduled appointments

What NOT to Do:

AvoidWhy
❌ "There's nothing wrong with you"Invalidating
❌ "It's all in your head"Dismissive
❌ "Just stop worrying"Unhelpful
❌ Repeated investigationsReinforces cycle
❌ Multiple reassurancesShort-term relief, Long-term worsening
❌ PRN appointmentsCome when anxious = Reinforcement

Psychological Treatment - Detailed

First-Line: Cognitive Behavioural Therapy (CBT)

CBT Components for Health Anxiety:

ComponentDescriptionGoal
PsychoeducationUnderstanding the anxiety cycleInsight
FormulationPersonalised model of their anxietyUnderstanding
Cognitive RestructuringChallenging catastrophic health beliefsReduce catastrophising
Behavioural ExperimentsTesting feared outcomesDisconfirm beliefs
ExposureTo feared health information/settingsHabituation
Response PreventionReducing safety behavioursBreak cycle
Reducing Reassurance-SeekingLimiting GP visits, Internet searchingBreak reinforcement
Interoceptive ExposureLearning to tolerate bodily sensationsReduce fear of symptoms
Relapse PreventionPlanning for setbacksMaintain gains

CBT Session Structure Example (8-16 Sessions):

SessionFocus
1-2Assessment, Formulation, Psychoeducation
3-4Cognitive restructuring, Identifying thoughts
5-6Behavioural experiments, Response prevention
7-8Exposure, Reducing safety behaviours
9-12Consolidation, Booster
13-16Relapse prevention, Ending

Evidence for CBT:

StudyFindings
Cochrane Review (Olatunji, 2014)CBT effective, Large effect sizes
Greeven et al., 2007CBT superior to placebo, Durable effects
Internet CBT (Hedman, 2014)Online CBT effective for health anxiety

Delivery Formats:

FormatNotes
Individual CBT8-16 sessions, Gold standard
Group CBTEffective, Cost-efficient
Guided Self-HelpBooks, Workbooks with therapist support
Computerised CBTE.g., SilverCloud, iCBT
Internet-Based CBTEvidence-based, Accessible

Other Psychological Approaches:

ApproachEvidenceNotes
Mindfulness-Based Cognitive Therapy (MBCT)ModerateMay help with acceptance
Acceptance and Commitment Therapy (ACT)GrowingFocus on values, Not symptom reduction
Psychodynamic TherapyLimitedLess evidence than CBT
HypnotherapyLimitedNot first-line

Pharmacological Treatment - Detailed

First-Line Pharmacotherapy (SSRIs):

MedicationStarting DoseTarget DoseNotes
Fluoxetine10-20mg OD40-60mg ODGood evidence, First-line
Paroxetine10-20mg OD40-50mg ODEvidence from RCTs
Sertraline50mg OD150-200mg ODAlternative SSRI
Escitalopram10mg OD20mg ODWell-tolerated
Citalopram10-20mg OD40mg ODAlternative

Second-Line Options:

MedicationDoseNotes
Clomipramine25-150mg ODTCA, If SSRI fails, More side effects
Venlafaxine75-225mg ODSNRI, Alternative

Prescribing Protocol:

StepAction
1.Start low (Half normal start dose)
2.Warn about initial worsening (May increase anxiety briefly)
3.Titrate slowly every 2-4 weeks
4.Adequate trial: 12 weeks at therapeutic dose
5.If inadequate response: Increase dose or switch
6.Continue 12+ months after remission

Indications for Pharmacotherapy:

IndicationNotes
Moderate-Severe health anxietyFirst-line alongside CBT
Comorbid depressionOften coexists
Patient preferenceIf declines CBT
CBT not available/UnsuccessfulStandalone option
Rapid symptom relief neededSSRIs act faster than CBT initially

Primary Care Management Strategies - Detailed

StrategyImplementationRationale
Regular Scheduled AppointmentsE.g., Monthly, FixedReduces PRN attendance
Single GP/Care CoordinatorContinuityAvoids doctor shopping
Explicit Investigation Agreement"We will do these tests once"Breaks investigation cycle
Review Results TogetherExplain clearly, OnceAvoids repeat explanations
Encourage Psychological TreatmentReferral to CBT/IAPTActive treatment
Treat ComorbiditiesScreen and treat depression, GADCommon and worsening
Set BoundariesPolitely limit reassuranceTherapeutic
Validate SufferingAlwaysTherapeutic relationship

Stepped Care Model

StepInterventionSetting
Step 1: RecognitionDiagnosis, Psychoeducation, Self-help materialsPrimary care
Step 2: Low-IntensityGuided self-help, Computerised CBT (SilverCloud)IAPT/Primary care
Step 3: High-IntensityIndividual CBT (8-16 sessions), SSRIIAPT/Psychology
Step 4: SpecialistLiaison psychiatry, Complex casesSecondary care
Step 5: TertiarySpecialist units (Rare)Tertiary

Consultation Skills for Health Anxiety

OSCE Communication Framework:

StepWhat to DoExample Statement
1. Open with EmpathyValidate"I can see this worry is really affecting your life"
2. Explore Health BeliefsUnderstand"What do you think might be causing these symptoms?"
3. PsychoeducationExplain"Health anxiety is a real condition where..."
4. ReframeName it"The good news is this is very treatable"
5. Limit InvestigationsAgree"We'll do one set of tests. If normal, That gives us our answer"
6. Offer TreatmentPlan"I'd like to refer you for CBT, Which is really effective"
7. Schedule Follow-UpContinuity"Let's meet in 4 weeks, Not before"
8. Close with HopeOptimism"Most people improve significantly with treatment"

8. Complications

Overview

CategoryKey Complications
PsychologicalDepression, Other anxiety, Suicidal ideation
SocialWork impairment, Relationship problems, Isolation
Medical/IatrogenicUnnecessary investigations, Harm from tests
FinancialHealthcare costs, Lost income

Psychological/Psychiatric Complications - Detailed

Depression:

AspectDetails
Prevalence40-60% comorbid
MechanismChronic worry, Functional impairment
ScreeningPHQ-9 at every assessment
TreatmentSSRIs help both, CBT for both

Other Anxiety Disorders:

DisorderRelationship
GAD30-50% comorbid, Overlapping worry
Panic Disorder20-40%, Somatic symptom overlap
OCD10-20%, Health-focused obsessions
Social AnxietyMay avoid medical settings

Suicidal Ideation:

Risk FactorNotes
Severe Health AnxietyDistress can be overwhelming
Comorbid DepressionSignificant increase in risk
Functional ImpairmentHopelessness
AssessmentAsk directly, PHQ-9 Q9, Risk assessment
ManagementSafety planning, Urgent referral if high risk

Substance Misuse:

SubstancePattern
AlcoholSelf-medication for anxiety
BenzodiazepinesMay seek prescriptions, Dependency risk
CannabisSome use to manage
ScreeningAUDIT, DAST

Social/Functional Complications - Detailed

ComplicationImpactManagement
Occupational ImpairmentAbsences, Unable to workOccupational health, Phased return
Relationship ProblemsPartners frustratedCouples therapy, Psychoeducation for family
Social IsolationWithdrawalSocial skills, Behavioural activation
Financial ImpactHealthcare costs, Lost incomeBenefits advice
Reduced Quality of LifeSignificantTreatment, Support

Medical/Iatrogenic Complications - Detailed

Unnecessary Investigations:

RiskConsequence
Radiation ExposureCT scans (Cumulative dose)
Contrast ReactionsAllergic reactions
Procedural RisksBleeding, Infection from invasive tests
Incidental Findings"Incidentalomas" leading to more tests
False PositivesFurther anxiety, More investigations

Iatrogenic Harm:

SourceExamples
Invasive TestsBiopsy complications
OvertreatmentUnnecessary medications
Increased AnxietyFrom more tests, Waiting for results

Healthcare System Impact:

FactorImpact
Doctor-ShoppingInconsistent care, Polypharmacy
High UtilisationCosts, Capacity
Clinician BurnoutFrustration, Difficult consultations
Delayed Diagnosis"Boy Who Cried Wolf" – Dismissed when ill

Prevention of Complications

StrategyHow
Early RecognitionScreen in primary care
Appropriate ManagementCBT, SSRIs - Not more tests
Limit InvestigationsExplicit agreement
Continuity of CareSingle GP/Coordinator
Screen for ComorbiditiesDepression, Anxiety, Substance misuse
Risk AssessmentSuicide risk if severe

9. Prognosis & Outcomes

Overview

FactorImpact on Prognosis
TreatmentSignificantly improves outcomes
DurationShorter = Better
SeverityMilder = Better
ComorbiditiesDepression, Personality disorder = Worse
EngagementGood engagement with therapy = Better

Natural History

CourseDetails
ChronicTends to wax and wane over years
FluctuatesWorse during stress, Life events
Without TreatmentTends to persist indefinitely
With TreatmentSignificant improvement in 50-70%
Spontaneous RemissionUncommon without treatment

Treatment Outcomes - Detailed

TreatmentResponse RateNotes
CBT50-70% significant improvementMost durable effects
SSRIs40-60% improvementNNT ~4-5
Combined CBT + SSRIMay be superiorFor severe cases
Guided Self-Help30-50%For mild-moderate
Internet CBTSimilar to face-to-faceHedman et al. 2014

Time to Response:

TreatmentTime
CBT4-8 weeks (Gradual)
SSRIs4-8 weeks (Onset), 12 weeks (Full effect)

Durability:

TreatmentFollow-Up
CBTEffects maintained at 1-2 years
SSRIsRelapse common if stopped early

Prognostic Factors

Better Prognosis:

FactorMechanism
Shorter DurationLess entrenched cognitions
Less Severe at BaselineEasier to treat
Good Insight"I know it's anxiety"
Engagement with CBTActive participation
Supportive RelationshipsFamily, Partner support
No Comorbid DepressionDepression worsens outcomes
No Personality DisorderCluster C particularly problematic
Younger AgeMore neuroplasticity

Worse Prognosis:

FactorMechanism
Long Duration (More than 5 years)Deeply entrenched
Comorbid Personality DisorderTreatment resistance
Severe DepressionNeeds treating first
Poor EngagementDoesn't attend, Doesn't do homework
Ongoing Life StressorsPerpetuating
Reinforcing Healthcare SystemMany investigations done
Avoidant SubtypeHarder to engage

Relapse Prevention

StrategyImplementation
Identify Warning SignsEarly symptoms of return
Maintenance StrategiesContinue CBT techniques
Booster Sessions3-6 monthly CBT follow-up
Medication Duration12+ months, Slow taper
Self-Help MaterialsBooks, Apps
LifestyleExercise, Sleep, Stress management

Long-Term Management Considerations

AspectApproach
Chronic ConditionMay need long-term support
MedicationMay need long-term SSRIs
PsychologicalPeriodic booster CBT
Healthcare CoordinationConsistent care, Limit investigations
ComorbiditiesTreat depression, Other anxiety
Quality of LifeFocus on function, Not symptom elimination

10. Evidence & Guidelines

Key Guidelines

GuidelineOrganisationYearKey Recommendations
DSM-5APA2013Diagnostic criteria (IAD, SSD)
ICD-11WHO2019Hypochondriasis (6B23)
NICE CG113NICE2011Common mental health disorders – Stepped care
NICE CG91NICE2009Treatment of depression (Overlap)

Key Evidence - Detailed

CBT for Health Anxiety (Cochrane Review, Olatunji et al., 2014)

AspectDetails
Study TypeMeta-analysis of RCTs
ResultCBT effective for reducing health anxiety
Effect SizeLarge (SMD ~0.9)
Follow-UpEffects maintained at 6-12 months
ImplicationCBT is first-line treatment
PMID24820200

SSRIs for Hypochondriasis (Fallon et al., 2017)

AspectDetails
Study TypeReview of RCTs
MedicationsFluoxetine, Paroxetine effective
Effect SizeModerate-Large
ImplicationSSRIs are effective for health anxiety
PMID28107906

Greeven et al., 2007 (RCT)

AspectDetails
Study TypeRCT
ArmsCBT vs Paroxetine vs Placebo
Samplen=112
ResultBoth CBT and Paroxetine superior to placebo
DurabilityCBT had most durable effects
PMID17261692

Hedman et al., 2014 (Internet CBT)

AspectDetails
Study TypeRCT
ArmsInternet CBT vs Group CBT
ResultInternet CBT non-inferior to face-to-face
ImplicationOnline CBT is a valid delivery method
PMID24917094

Tyrer et al., 2016 (BMJ Review)

AspectDetails
Study TypeClinical review
RecommendationsCBT first-line, SSRIs second-line
Key PointAvoid repeated investigations
PMID27075540

11. Patient/Layperson Explanation

What is Health Anxiety?

Health anxiety is when you worry a lot about your health, even when doctors have told you that you're okay. It's a very common condition that affects about 1 in 20 people. You might:

  • Keep thinking you have a serious illness
  • Keep checking your body for signs of disease
  • Look up symptoms on the internet a lot ("Dr Google")
  • Go to the doctor frequently for reassurance
  • Feel briefly relieved after tests are normal, but then start worrying again

Key Points to Understand

FactExplanation
Common1-5% of people have health anxiety
Real ConditionIt's a recognised medical condition
Not "Making It Up"Your symptoms and distress are REAL
TreatableVery effective treatments available
Chronic but ManageableCan wax and wane, But can be controlled

Why Does It Happen?

It's related to how your brain processes worry. When you notice a normal body sensation (like a headache or a fast heartbeat), your brain jumps to the worst-case scenario. This triggers anxiety, which causes MORE body symptoms (Sweating, Racing heart, Muscle tension), which makes you worry MORE. It becomes a cycle.

The Anxiety Cycle:

StepWhat Happens
1. TriggerYou notice a body sensation (Headache, Palpitation)
2. Thought"This could be something serious (Cancer, Heart attack)"
3. AnxietyYou feel scared, Your body reacts (More symptoms!)
4. BehaviourYou check your body, Google, Go to doctor
5. Brief ReliefYou feel better temporarily
6. ReturnThe worry comes back, Often worse

Is It "All in My Head"?

No. The symptoms you feel are REAL. But they're caused by anxiety, not by the serious disease you're worried about. Health anxiety is a recognised medical condition that is very treatable.

MythTruth
❌ "You're imagining it"✅ Symptoms are real
❌ "Just stop worrying"✅ It's a condition that needs treatment
❌ "One more test will fix it"✅ Tests don't fix health anxiety
❌ "You're wasting doctors' time"✅ You have a real condition

How Is It Treated?

1. Cognitive Behavioural Therapy (CBT) - The Most Effective Treatment

What It IsHow It Helps
Talking therapyWith a specialist psychologist or therapist
8-16 sessionsWeekly or fortnightly
Learn about the cycleUnderstand why it happens
Challenge thoughtsLearn to question catastrophic thinking
Change behavioursReduce checking, Googling, Reassurance-seeking
Face fearsGradually learn to tolerate uncertainty

2. Medication (SSRIs)

What It IsHow It Helps
AntidepressantsLike Fluoxetine, Sertraline
Not just for depressionVery effective for anxiety
Takes 4-6 weeksTo work fully
Prescribed by GPEasy to access

What Can I Do to Help Myself?

Do:

StrategyHow to Do It
✅ Limit checkingSet a rule: No more than once a day
✅ Limit GooglingTry to stop completely
✅ Reduce reassurance-seekingAsk for reassurance once, Not repeatedly
✅ Schedule GP appointmentsRather than going when anxious
✅ Talk to your GP about CBTAsk for a referral
✅ ExerciseHelps reduce anxiety
✅ Practice relaxationDeep breathing, Meditation
✅ Distract yourselfWhen urge to check arises

Don't:

AvoidWhy
❌ Body checkingIncreases focus on symptoms
❌ "Dr Google"Almost always makes things worse
❌ Repeated reassuranceBrief relief, Then worse
❌ Avoiding health topics completelyAvoidance maintains anxiety

Frequently Asked Questions (FAQs)

QuestionAnswer
Am I making this up?No. Health anxiety is a real, Recognised condition.
Could it still be a serious illness?One normal investigation is enough. The anxiety is the problem.
Will more tests help?No. Tests provide brief relief, Then worry returns.
Why can't I stop worrying?It's a condition, Not a choice. Treatment helps.
Will I always be like this?No. Most people improve significantly with treatment.
Can I have CBT?Yes. Ask your GP for a referral.
Do I need medication?Not always. CBT alone often works. Medication helps if severe or with depression.
How long does treatment take?CBT: 8-16 weeks. Medication: 6-12 months. Improvement often seen within weeks.

When to Seek Help

[!CAUTION] See your doctor urgently if:

  • You're having thoughts of harming yourself
  • You feel you can't cope
  • Your anxiety is severely affecting your life
  • You're using alcohol or drugs to cope

Family and Friends

What HelpsWhat Doesn't
✅ Listen without judgement❌ "There's nothing wrong with you"
✅ Encourage treatment❌ Repeatedly reassuring
✅ Be patient❌ Getting frustrated
✅ Set gentle boundaries❌ Enabling checking behaviours

Support Resources

OrganisationWebsiteWhat They Offer
NHS Choiceswww.nhs.uk/conditions/health-anxietyInformation, Self-help
Anxiety UKwww.anxietyuk.org.ukSupport, Therapy
Mindwww.mind.org.ukMental health charity
No More Panicwww.nomorepanic.co.ukPeer support
IAPTNHS Talking TherapiesFree CBT via NHS

Self-Help Books

BookAuthor
Overcoming Health AnxietyDr David Veale and Rob Willson
It's Not All in Your HeadDr Gordon Asmundson and Dr Steven Taylor
Break Free from OCDFiona Challacombe (Health anxiety has overlaps)

12. References

Primary Guidelines

  1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5). APA. 2013.

  2. World Health Organization. ICD-11 for Mortality and Morbidity Statistics. WHO. 2019.

  3. NICE. Common mental health problems: Identification and pathways to care (CG123). NICE. 2011.

Key Evidence

  1. Olatunji BO, et al. Efficacy of cognitive-behavioral therapy for health anxiety: A meta-analysis. J Anxiety Disord. 2014;28(5):453-462. PMID: 24820200

  2. Greeven A, et al. Cognitive behavior therapy and paroxetine in the treatment of hypochondriasis. Am J Psychiatry. 2007;164(1):91-99. PMID: 17261692

  3. Fallon BA, et al. Pharmacotherapy of somatoform disorders. J Psychosom Res. 2017;93:8-14. PMID: 28107906

Reviews

  1. Tyrer P. Recent advances in the understanding and treatment of health anxiety. Curr Psychiatry Rep. 2018;20(7):49. PMID: 29876651

  2. Asmundson GJG, et al. Health anxiety: Current perspectives and future directions. Curr Psychiatry Rep. 2010;12(4):306-312. PMID: 20556663

Additional References

  1. Taylor S, Asmundson GJG. Treating Health Anxiety: A Cognitive-Behavioral Approach. Guilford Press. 2004.

  2. Salkovskis PM, et al. Cognitive-behavioural approach to understanding obsessional thinking. Br J Psychiatry. 1995;167(Suppl 27):87-95.

  3. Bobevski I, et al. Excessive health anxiety—Hypochondriasis and illness anxiety disorder: Conceptualization and treatment. Curr Psychiatry Rep. 2016;18(5):44. PMID: 26993792

  4. Hedman E, et al. Internet-based CBT vs. cognitive behavioral group therapy for health anxiety. JAMA Psychiatry. 2014;71(8):915-924. PMID: 24917094

  5. Fink P, et al. The epidemiology of somatisation. J Psychosom Res. 2009;66(1):3-8. PMID: 19064042

  6. Tyrer P, et al. Health Anxiety. BMJ. 2016;353:i1755. PMID: 27075540

  7. Newby JM, et al. Systematic review and meta-analysis of transdiagnostic psychological treatments for anxiety and depressive disorders in adulthood. Clin Psychol Rev. 2015;40:91-110. PMID: 26094079


13. Examination Focus

High-Yield Facts for Exams

FactValueExam Importance
DefinitionPreoccupation with having/acquiring serious illnessCore knowledge
DSM-5 ClassificationsIAD (Minimal symptoms) vs SSD (Symptoms present)Must know
Prevalence1-5%Commonly asked
Peak Age20-40 yearsKnow this
SexEqual or slight female predominanceBackground
First-Line TreatmentCBTMust know
PharmacotherapySSRIs (Fluoxetine, Paroxetine)Must know
Key DistinctionIAD = No/Minimal symptomsCritical
Cognitive ModelTrigger → Misinterpretation → Anxiety → Safety behaviourMust know
Common Feared IllnessesCancer, Heart disease, NeurologicalBackground
Reassurance ProblemBrief relief, Then return of anxietyKey concept
CyberchondriaExcessive internet health searchingModern phenomenon

Common Exam Questions - Detailed

Diagnosis Questions:

  1. "A 35-year-old woman presents with persistent worry that she has cancer, despite multiple normal investigations. She checks her body daily and frequently consults her GP. What is the diagnosis?"

    • Model Answer: "This is Illness Anxiety Disorder (IAD) based on DSM-5 criteria. Key features: Preoccupation with having a serious illness (Cancer), Minimal or absent somatic symptoms (Normal investigations), Excessive health-related behaviours (Body checking, Frequent GP visits), Duration Greater than 6 months. Important to exclude genuine medical conditions with appropriate one-off investigation."
  2. "What is the key difference between Illness Anxiety Disorder and Somatic Symptom Disorder?"

    • Model Answer: "The key distinction is the presence of somatic symptoms. In IAD, There are minimal or NO significant somatic symptoms – The problem is the PREOCCUPATION. In SSD, There ARE significant, Distressing somatic symptoms – The problem is excessive thoughts and behaviours ABOUT those symptoms. Both require duration Greater than 6 months."
  3. "How would you assess a patient with suspected health anxiety?"

    • Model Answer: "I would take a comprehensive history exploring: Nature of health concerns, Duration and pattern of symptoms, Previous investigations and their effect on anxiety, Health-related behaviours (Checking, Googling, Reassurance-seeking), Functional impact, Psychiatric history (Depression, GAD, OCD), Medical history, Family history of serious illness. MSE focusing on mood, Anxiety, Insight. Appropriate physical examination. Screening tools (HAI, PHQ-9, GAD-7)."

Treatment Questions:

  1. "What is the first-line treatment for health anxiety?"

    • Model Answer: "Cognitive Behavioural Therapy (CBT) is the gold-standard first-line treatment. It has strong evidence from meta-analyses (Olatunji 2014) and RCTs (Greeven 2007). CBT for health anxiety includes: Psychoeducation about the anxiety cycle, Cognitive restructuring of catastrophic health beliefs, Behavioural experiments, Exposure and response prevention (Reducing safety behaviours), And relapse prevention. Typically 8-16 sessions. Can be delivered individually, In groups, Or via internet-based formats."
  2. "Why should you avoid repeated investigations in health anxiety?"

    • Model Answer: "Repeated investigations reinforce the anxiety cycle. The sequence is: Investigation → Normal result → Brief reassurance → Anxiety returns → Request for more investigation. This provides negative reinforcement (Temporary relief), Making the behaviour more likely to recur. It does NOT address the underlying cognitive distortions. One appropriate investigation is sufficient to exclude serious pathology."
  3. "Which medications are effective for health anxiety?"

    • Model Answer: "SSRIs are the first-line pharmacological treatment. Evidence supports Fluoxetine (20-60mg) and Paroxetine (20-50mg) from RCTs. Other SSRIs (Sertraline, Escitalopram) are reasonable alternatives. Start at low dose, Titrate slowly, Trial for 12 weeks at therapeutic dose. Indications: Moderate-severe anxiety, Comorbid depression, If CBT unavailable or unsuccessful. Can be used alone or combined with CBT."

OSCE Stations

Station 1: History Taking - Health Anxiety

TaskExpected Competencies
Elicit presenting complaint"What brings you here today?"
Explore health beliefs"What do you think might be causing these symptoms?"
Assess behaviours"Do you find yourself checking your body or searching the internet?"
Explore previous investigations"What tests have you had? How did you feel after?"
Assess reassurance pattern"After tests are normal, How long do you feel reassured?"
Functional impact"How is this affecting your work, Relationships, Daily life?"
Screen for depression"How has your mood been? Any thoughts of harming yourself?"
Screen for other anxiety"Do you worry about other things too?"
Summarise and signpost"It sounds like you're experiencing health anxiety. This is very treatable."

Station 2: Explaining Diagnosis to Patient

ComponentExpected Points
Introduces selfName, Role
Validates distress"I can see this worry is really affecting you"
Avoids dismissalDo NOT say "There's nothing wrong"
Explains condition"Health anxiety is a real, Recognised medical condition"
Explains the cycleTrigger → Thought → Anxiety → Behaviour → Maintenance
Normalises"It's very common – About 1 in 20 people"
Offers hope"It's very treatable"
Outlines treatment"CBT is very effective. Medication can also help."
Addresses investigations"More tests won't help. We've ruled out serious illness."
Answers questions"Do you have any questions or concerns?"

Station 3: Managing Requests for Investigation

ScenarioAppropriate Response
Patient requests more tests"I understand the anxiety. However, We've done appropriate tests. More tests will not help your anxiety."
Patient frustrated with diagnosis"I hear your frustration. This doesn't mean it's not real – Your symptoms ARE real. The anxiety is causing them."
Patient wants second opinion"That's your right. However, I'd encourage you to consider the psychological treatment, Which is very effective."
Patient says "What if you're wrong?""Medicine involves uncertainty. We've done appropriate assessment. More tests carry their own risks."

Viva Points - Expanded

Opening Statement:

"Health anxiety, classified in DSM-5 as Illness Anxiety Disorder, is characterised by preoccupation with having or acquiring a serious illness, despite minimal or absent somatic symptoms and normal investigations. It is maintained by a cognitive-behavioural cycle of catastrophic misinterpretation, anxiety, and safety behaviours. It affects 1-5% of the population and is distinct from Somatic Symptom Disorder, where significant symptoms ARE present."

Key Facts Table:

CategoryKey Facts
Prevalence1-5% general population, 3-8% primary care
ClassificationsDSM-5: IAD (No symptoms) vs SSD (Symptoms present)
Common FearsCancer, Heart disease, Neurological conditions
Cognitive ModelTrigger → Misinterpretation → Anxiety → Safety behaviour → Maintenance
TreatmentCBT first-line (Strong evidence), SSRIs effective adjunct
AvoidRepeated investigations, Excessive reassurance, Dismissing patient
PrognosisChronic but treatable, 50-70% improve with CBT

Evidence to Cite:

StudyWhat It Showed
Greeven et al. (2007)RCT: CBT and Paroxetine both effective, CBT more durable
Olatunji et al. (2014)Cochrane: CBT effective for health anxiety, Large effect
Hedman et al. (2014)Internet CBT effective for health anxiety

Common Mistakes

What Fails Candidates:

MistakeCorrect Approach
❌ Not knowing DSM-5 distinction (IAD vs SSD)IAD = No symptoms, SSD = Symptoms present
❌ Recommending repeated investigationsOne appropriate investigation only
❌ Dismissing patient's distressValidate: "Your symptoms are real"
❌ Not mentioning CBT as first-lineCBT is gold standard
❌ Forgetting comorbid depression screeningScreen with PHQ-9
❌ Saying "It's all in your head"Avoid invalidating language
❌ Not explaining the anxiety cycleKey to patient understanding

Dangerous Clinical Errors:

ErrorWhy It Matters
⚠️ Dismissing genuine new symptoms"Boy Who Cried Wolf" problem – May miss real illness
⚠️ Not assessing suicide riskSevere health anxiety can lead to suicidal ideation
⚠️ Reinforcing with investigationsMaintains the anxiety cycle

Examiner Follow-Up Questions

QuestionExpected Answer
"What is cyberchondria?"Excessive internet searching for health information, Worsens anxiety
"Why doesn't reassurance work?"Brief relief, Doesn't address core cognitions, Negatively reinforced
"What are safety behaviours?"Body checking, Googling, Reassurance-seeking – Maintain anxiety
"What comorbidities should you screen for?"Depression (40-60%), GAD (30-50%), Panic, OCD
"What is the cognitive model?"Trigger → Catastrophic misinterpretation → Anxiety → Safety behaviour → Cycle maintained

Differential Diagnosis

ConditionKey Distinguishing Features
Somatic Symptom DisorderSignificant somatic symptoms ARE present
Generalised Anxiety DisorderWorry about MANY topics, Not just health
Panic DisorderDiscrete panic attacks, Not constant preoccupation
OCDObsessions/Compulsions beyond health focus
Delusional Disorder (Somatic Type)Fixed false belief, No insight
Depression with Somatic FocusLow mood predominant, Health worry secondary
Genuine Medical ConditionMust always consider and appropriately investigate

Last Reviewed: 2025-12-25 | MedVellum Editorial Team


Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. Clinical decisions should account for individual patient circumstances. Always consult appropriate specialists and current guidelines.

Last updated: 2025-12-25

At a Glance

EvidenceHigh
Last Updated2025-12-25

Red Flags

  • Suicidal Ideation
  • Severe Functional Impairment
  • Comorbid Depression
  • Substance Misuse

Clinical Pearls

  • **"Reassurance Doesn't Work Long-Term"**: Brief relief followed by return of anxiety. Avoid reassurance-seeking cycles.
  • **"IAD = Minimal Symptoms; SSD = Significant Symptoms"**: Key DSM-5 distinction – Know this for exams.
  • **"Cyberchondria"**: Modern phenomenon – Excessive health-related internet searching worsens anxiety.
  • **"High Users of Healthcare"**: Often significant healthcare utilisation without benefit, Costly.
  • **"CBT is First-Line"**: Strong evidence base. SSRIs as adjunct or if comorbid depression.

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines