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Orthopaedics
Paediatrics

Koehler Disease

High EvidenceUpdated: 2025-12-26

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Red Flags

  • Adult Onset -> Muller-Weiss Syndrome (Not Koehler's)
  • Night Pain -> Leukemia/Osteoid Osteoma
  • Fever -> Osteomyelitis
  • Severe Cavus -> Neurological cause
Overview

Koehler Disease

1. Clinical Overview

Summary

Koehler Disease (often spelled Kohler's) is a rare, self-limiting avascular necrosis (osteochondrosis) of the tarsal navicular bone affecting young children (Boys 4-7 years old). It presents as a limping child with pain and swelling over the medial midfoot. The navicular, which is the last tarsal bone to ossify, undergoes a temporary interruption of blood supply, causing it to collapse and become sclerotic (dense). The classic radiographic appearance is a flattened, wafer-thin, white bone ("Silver Dollar Sign"). Crucially, unlike adult AVN (Muller-Weiss), Koehler's disease has an excellent prognosis. It spontaneously revascularizes and reconstitutes over 1-3 years, usually leaving no long-term deformity or pain. [1,2,3]

Key Facts

  • The Last Bone: The Navicular is the last foot bone to ossify (Age 2-3 in girls, 4-5 in boys). This delayed ossification makes it vulnerable to compression between the already-ossified Talus and Cuneiforms.
  • The Sclerosis: On X-ray, the bone looks "dead" (bright white and squashed). Parents panic. You must reassure them: "This looks bad, but it heals perfectly on its own."
  • The Difference:
    • Koehler's: Child (Start). Biological plasticity. Heals.
    • Muller-Weiss: Adult (End). Biological failure. Crumbles.

Clinical Pearls

"Walk it off": Many kids with Koehler's continue to run and play despite the limp. The pain is rarely severe enough to stop activity completely.

"The Comma": Sometimes the collapsing navicular takes on a comma shape on the lateral view before it reforms.

"Don't Operate": There is absolutely no role for surgery in Koehler's disease. Biopsy or drilling will only damage the cartilage and potential growth plate.


2. Epidemiology

Demographics

  • Age: 3-7 years (Peak age 5). (Rare >9).
  • Gender: Boys > Girls (5:1).
  • Bilateral: 25% of cases (but often asynchronous onset).

3. Pathophysiology

Anatomy

  • Blood Supply: The navicular is supplied by a centripetal network from the dorsalis pedis and medial plantar arteries.
  • Vascular Watershed: The central body of the navicular is a watershed zone (poor perfusion), similar to the scaphoid waist.

Mechanism

  • Compression: As the child grows and becomes more active (jumping), the cartilaginous navicular is compressed between the Talus and Cuneiforms. The vessels are squeezed, leading to ischemia and osteocyte death.
  • Revascularization: Creeping substitution occurs. New vessels grow in, removing dead bone and laying down new bone.

4. Clinical Presentation

Symptoms

Signs


Limp
Antalgic gait (walking on lateral border of foot).
Pain
Medial midfoot.
Timing
Subacute onset (weeks/months).
5. Investigations

Imaging

  • X-Ray (Weight Bearing):
    • AP/Lateral:
      • Sclerosis: Increased density (Whiter than other bones).
      • Flattening: Loss of height (Wafer-like).
      • Fragmentation: Breaking into pieces.
  • MRI:
    • Rarely needed.
    • Shows loss of signal on T1 (AVN) and marrow edema on T2.
  • Bone Scan:
    • Cold spot (early) -> Hot spot (healing).

6. Management Algorithm
                 CHILD LIMPING
                       ↓
              X-RAY: DENSE NAVICULAR
            ┌───────────┴───────────┐
          MILD PAIN            SEVERE PAIN
        (Can walk)           (Refuses to walk)
             ↓                      ↓
     ACTIVITY MODIFICATION    SHORT LEG CAST
     (Arch Support / Shoe)      (4-6 Weeks)
             ↓                      ↓
         FOLLOW UP              RE-XRAY
        (X-ray 6m)           (Document healing)

7. Management: Conservative

Protocol

  • Observation:
    • If symptoms are mild, no treatment is needed other than avoiding high-impact sports.
    • Soft arch support cushion.
  • Immobilization (The Standard):
    • Short Leg Walking Cast: 4-6 weeks.
    • Purpose: Relieves pain and inflammation. Does not speed up the revascularization (which takes years) but makes the child comfortable.
    • Williams et al: Showed that casting reduces the duration of symptoms (3 months vs 15 months for untreated).

8. Management: Surgical

Contraindicated

  • Surgery has NO role.
  • Drilling, grafting, or excision are harmful.

9. Complications

Flattened Navicular

  • The bone may reconstitute in a slightly flattened shape. Usually asymptomatic.

Osteophytes

  • Rarely, dorsal dorsal osteophytes form.

TN Arthritis

  • Extremely rare in childhood onset.

10. Evidence & Guidelines

To Cast or Not?

  • Williams et al (JBJS 1983): A classic study comparing casting vs arch supports vs nothing.
    • Cast: Pain resolved in 3 months.
    • Support: Pain resolved in 7 months.
    • Nothing: Pain resolved in 15 months.
    • Conclusion: Casting is the most effective treatment for symptoms.

Long Term Outcome

  • Ippolito et al (JPO 1984): Followed patients for 33 years. Found normal foot function and no arthritis in adulthood, regardless of the severity of the initial X-ray.

11. Patient Explanation

The Condition

The "keystone" bone in your son's foot has temporarily lost its blood supply. It's like a grape turning into a raisin.

The Good News

In children, this "raisin" will turn back into a grape. The bone has an amazing ability to heal itself. It will grow back to normal shape.

The Plan

We will put him in a cast for 4 weeks to stop the pain. Then he can run and play as much as he likes. It will heal perfectly.


12. References
  1. Williams GA, Cowell HR. Kohler's disease of the tarsal navicular. Clin Orthop Relat Res. 1981.
  2. Ippolito E, et al. Long-term follow-up of Kohler's disease of the tarsal navicular. J Pediatr Orthop. 1984.
  3. Karp MG. Kohler's disease of the tarsal scaphoid: an end-result study. J Bone Joint Surg Am. 1937.
13. Examination Focus (Viva Vault)

Q1: At what age does the tarsal navicular normally ossify? A: Girls: 2-3 years. Boys: 4-5 years. It is the last tarsal bone to ossify.

Q2: Differentiate Koehler's Disease from Muller-Weiss Syndrome. A:

  • Koehler's: Childhood (4-7), Males, Spontaneous vascular etiology, Reconstitutes to normal, Excellent prognosis.
  • Muller-Weiss: Adulthood (40-60), Females, Dysplastic/Traumatic etiology, Fragments and collapses, Poor prognosis (Arthritis).

Q3: Does the severity of radiographic fragmentation correlate with outcome? A: No. Even completely fragmented and flattened naviculars in children reconstitute to a normal or near-normal shape with normal function.

Q4: What is the primary differential diagnosis for a dense navicular in a child? A: Normal irregular ossification. The navicular can often ossify from multiple centers, appearing fragmented. Clinical correlation (pain/limp) is essential to diagnose Koehler's.

(End of Topic)

Last updated: 2025-12-26

At a Glance

EvidenceHigh
Last Updated2025-12-26

Red Flags

  • Adult Onset -> Muller-Weiss Syndrome (Not Koehler's)
  • Night Pain -> Leukemia/Osteoid Osteoma
  • Fever -> Osteomyelitis
  • Severe Cavus -> Neurological cause

Clinical Pearls

  • **"Walk it off"**: Many kids with Koehler's continue to run and play despite the limp. The pain is rarely severe enough to stop activity completely.
  • **"The Comma"**: Sometimes the collapsing navicular takes on a comma shape on the lateral view before it reforms.
  • **"Don't Operate"**: There is absolutely no role for surgery in Koehler's disease. Biopsy or drilling will only damage the cartilage and potential growth plate.

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines