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EMERGENCY

Acute Respiratory Distress - Paediatric

High EvidenceUpdated: 2025-12-25

On This Page

Red Flags

  • Severe respiratory distress
  • Respiratory failure
  • Signs of exhaustion
  • Cyanosis
  • Altered mental status
  • Signs of impending respiratory arrest
Overview

Acute Respiratory Distress - Paediatric

1. Clinical Overview

Summary

Acute respiratory distress in children is difficulty breathing or inadequate breathing, which can be caused by many conditions affecting the airways, lungs, or breathing muscles. Think of breathing as your child's body getting oxygen in and carbon dioxide out—when something interferes with this process (blocked airways, lung problems, breathing muscle weakness), your child has to work harder to breathe, causing respiratory distress. This is a medical emergency that can progress rapidly to respiratory failure (inability to breathe adequately) and death if not treated promptly. The most common causes vary by age—in infants, it's often bronchiolitis or pneumonia; in older children, it's often asthma, pneumonia, or croup. The presentation can be subtle in infants (may just be grunting, nasal flaring, or poor feeding) or more obvious in older children (obvious difficulty breathing). The key to management is recognizing respiratory distress early (increased work of breathing, tachypnea, use of accessory muscles, grunting, nasal flaring), assessing severity, providing immediate support (oxygen, positioning, may need ventilation), treating the underlying cause, and monitoring closely. Early recognition and treatment are crucial—respiratory distress can progress rapidly to respiratory failure.

Key Facts

  • Definition: Difficulty breathing or inadequate breathing
  • Incidence: Very common (thousands of cases/year)
  • Mortality: Low (<1%) with prompt treatment, higher if delayed
  • Peak age: Infants and young children (highest risk)
  • Critical feature: Increased work of breathing, tachypnea, signs of distress
  • Key investigation: Clinical assessment (usually sufficient)
  • First-line treatment: Oxygen, treat underlying cause, may need ventilation

Clinical Pearls

"Work of breathing is key" — Look for increased work of breathing (use of accessory muscles, intercostal recession, subcostal recession, tracheal tug, head bobbing). This is more important than just the respiratory rate.

"Infants show different signs" — Infants may show subtle signs (grunting, nasal flaring, poor feeding) rather than obvious difficulty breathing. Always look for these signs in infants.

"Don't wait for cyanosis" — Cyanosis is a late sign. If a child is cyanotic, they're in severe respiratory failure. Treat before they become cyanotic.

"Respiratory distress can progress rapidly" — Children, especially infants, can deteriorate very quickly. Don't wait—if you suspect respiratory distress, assess and treat urgently.

Why This Matters Clinically

Respiratory distress is a medical emergency that can progress rapidly to respiratory failure and death if not treated promptly. Early recognition (especially in infants where signs may be subtle), immediate support (oxygen, positioning), and treating the underlying cause are essential. This is a condition that all clinicians caring for children need to recognize and manage urgently, as delayed treatment can be fatal.


2. Epidemiology

Incidence & Prevalence

  • Overall: Very common (thousands of cases/year)
  • Trend: Stable (common condition)
  • Peak age: Infants and young children (highest risk)

Demographics

FactorDetails
AgeHighest risk in infants and young children (<5 years)
SexVaries by cause (asthma = slight male predominance)
EthnicityHigher in certain populations (asthma, etc.)
GeographyHigher in resource-poor settings
SettingEmergency departments, pediatric ICU, hospitals

Risk Factors

Non-Modifiable:

  • Age (infants and young children = highest risk)
  • Prematurity (higher risk)
  • Chronic lung disease (higher risk)

Modifiable:

Risk FactorRelative RiskMechanism
Asthma5-10xAirway obstruction
Infections3-5xPneumonia, bronchiolitis
Smoking exposure2-3xWorsens respiratory conditions
No vaccinations2-3xIncreased infection risk

Common Causes

CauseFrequencyTypical Patient
Bronchiolitis30-40%Infants, winter
Asthma20-30%Older children
Pneumonia15-20%All ages
Croup10-15%Young children
Other10-15%Various

3. Pathophysiology

The Respiratory Distress Mechanism

Step 1: Underlying Problem

  • Airway obstruction: Blocked airways (asthma, croup, foreign body)
  • Lung problems: Lung disease (pneumonia, bronchiolitis, ARDS)
  • Breathing muscle weakness: Weak muscles (neuromuscular disease)
  • Result: Breathing becomes difficult

Step 2: Increased Work of Breathing

  • Compensation: Body tries to compensate
  • Increased effort: Works harder to breathe
  • Accessory muscles: Uses extra muscles
  • Result: Increased work of breathing

Step 3: Clinical Manifestation

  • Tachypnea: Fast breathing
  • Signs of distress: Use of accessory muscles, recession, grunting
  • Result: Respiratory distress visible

Step 4: Respiratory Failure (If Not Treated)

  • Inadequate breathing: Can't breathe adequately
  • Hypoxia: Low oxygen
  • Hypercapnia: High carbon dioxide
  • Result: Respiratory failure, death

Classification by Cause

CauseMechanismClinical Features
Airway obstructionBlocked airwaysStridor, wheeze, difficulty breathing
Lung diseaseLung problemsTachypnea, crackles, difficulty breathing
Breathing muscle weaknessWeak musclesShallow breathing, difficulty breathing

Anatomical Considerations

Respiratory System:

  • Upper airways: Nose, mouth, throat
  • Lower airways: Trachea, bronchi, lungs
  • Breathing muscles: Diaphragm, intercostal muscles

Why Children are Vulnerable:

  • Smaller airways: More easily blocked
  • Less reserve: Less ability to compensate
  • Rapid deterioration: Can deteriorate quickly

4. Clinical Presentation

Symptoms: The Patient's Story

Typical Presentation:

Infants (May Be Subtle):

Older Children:

Signs: What You See

Vital Signs (Abnormal):

SignFindingSignificance
Respiratory rateHigh (tachypnea)Respiratory distress
Heart rateMay be high (compensatory)Tachycardia
SpO2May be lowHypoxia
TemperatureMay be elevated (if infection)Fever

General Appearance:

Respiratory Examination:

FindingWhat It MeansFrequency
TachypneaFast breathingAlways
Use of accessory musclesWorking hard to breathe70-80%
Intercostal recessionSucking in between ribs60-70%
Subcostal recessionSucking in below ribs50-60%
Tracheal tugSucking in at neck40-50%
Head bobbingHead bobbing with breathing (infants)30-40% (infants)
GruntingGrunting sounds (infants)30-40% (infants)
Nasal flaringFlaring nostrils40-50%
CyanosisBlue color (late sign)10-20% (if severe)

Auscultation:

FindingWhat It MeansFrequency
WheezeAirway obstruction (asthma, bronchiolitis)40-50%
CracklesLung disease (pneumonia)30-40%
StridorUpper airway obstruction (croup)10-20%
Decreased air entrySevere disease20-30% (if severe)

Signs of Exhaustion (Critical):

Red Flags

[!CAUTION] Red Flags — Immediate Escalation Required:

  • Severe respiratory distress — Medical emergency, needs urgent support
  • Respiratory failure — Medical emergency, needs urgent ventilation
  • Signs of exhaustion — Medical emergency, respiratory arrest imminent
  • Cyanosis — Medical emergency, severe respiratory failure
  • Altered mental status — Medical emergency, needs urgent assessment
  • Signs of impending respiratory arrest — Medical emergency, needs urgent ventilation

Difficulty breathing
Obvious or subtle
Fast breathing
Tachypnea
Other
Varies by cause
5. Clinical Examination

Structured Approach: ABCDE

A - Airway

  • Assessment: May be compromised (obstruction, decreased consciousness)
  • Action: Secure if compromised (may need intubation)

B - Breathing

  • Look: Increased work of breathing, signs of distress
  • Listen: Wheeze, crackles, stridor, decreased air entry
  • Measure: SpO2 (may be low), respiratory rate (usually high)
  • Action: Oxygen urgently, may need ventilation

C - Circulation

  • Look: May have signs of shock (if severe)
  • Feel: Pulse (may be fast), BP (usually normal, may be low if severe)
  • Listen: Heart sounds (usually normal)
  • Measure: BP (usually normal), HR (may be high)
  • Action: Monitor if severe

D - Disability

  • Assessment: Mental status (may be altered if severe)
  • Action: Assess if severe

E - Exposure

  • Look: Respiratory examination, look for cause
  • Listen: Auscultation
  • Action: Complete examination, identify cause

Specific Examination Findings

Work of Breathing Assessment (Critical):

SignTechniqueFindingClinical Use
Accessory musclesLook at neck, shouldersUsing extra musclesIncreased work
Intercostal recessionLook between ribsSucking inIncreased work
Subcostal recessionLook below ribsSucking inIncreased work
Tracheal tugLook at neckSucking inIncreased work
Head bobbingLook at head (infants)Bobbing with breathingIncreased work (infants)
GruntingListen (infants)Grunting soundsIncreased work (infants)
Nasal flaringLook at noseFlaring nostrilsIncreased work

Auscultation:

FindingWhat It MeansClinical Use
WheezeAirway obstructionAsthma, bronchiolitis
CracklesLung diseasePneumonia
StridorUpper airway obstructionCroup, foreign body
Decreased air entrySevere diseaseMay need ventilation

Special Tests

TestTechniquePositive FindingClinical Use
SpO2Pulse oximeterLow (<92%)Hypoxia
Respiratory rateCount breathsHigh (age-specific)Tachypnea
Chest X-rayIf neededMay show causeIdentifies cause

6. Investigations

First-Line (Bedside) - Do Immediately

1. Clinical Assessment (Most Important)

  • Work of breathing: Assess increased work
  • Auscultation: Listen for wheeze, crackles, stridor
  • Action: Usually sufficient for diagnosis and severity assessment

2. SpO2 (Essential)

  • Purpose: Assess oxygenation
  • Finding: May be low
  • Action: Essential for monitoring

Laboratory Tests

TestExpected FindingPurpose
Arterial blood gasMay show hypoxia, hypercapniaAssesses gas exchange
Full Blood CountMay show leukocytosis (if infection)Identifies infection
CRPMay be elevated (if infection)Identifies infection

Imaging

Chest X-Ray (If Needed):

IndicationFindingClinical Note
Uncertain diagnosisMay show cause (pneumonia, etc.)If needed to identify cause

Diagnostic Criteria

Clinical Diagnosis:

  • Increased work of breathing + tachypnea + signs of distress = Respiratory distress

Severity Assessment:

  • Mild: Slight increase in work, good function
  • Moderate: Obvious increase in work, some dysfunction
  • Severe: Severe increase in work, exhaustion, respiratory failure

7. Management

Management Algorithm

        RESPIRATORY DISTRESS (CHILD)
    (Difficulty breathing + signs of distress)
                    ↓
┌─────────────────────────────────────────────────┐
│         IMMEDIATE ASSESSMENT (ABCDE)            │
│  • Airway, Breathing, Circulation               │
│  • Assess work of breathing                      │
│  • SpO2 (essential)                              │
│  • This is the priority                           │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         OXYGEN (URGENT)                          │
│  • High-flow oxygen                               │
│  • Don't wait—give oxygen immediately             │
│  • Monitor SpO2                                    │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         IDENTIFY CAUSE                           │
│  • History, examination, auscultation            │
│  • Chest X-ray if needed                          │
│  • Identify: asthma, pneumonia, bronchiolitis, etc. │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         TREAT UNDERLYING CAUSE                    │
├─────────────────────────────────────────────────┤
│  ASTHMA                                          │
│  → Bronchodilators (salbutamol)                  │
│  → Steroids (prednisolone)                       │
│                                                  │
│  PNEUMONIA                                       │
│  → Antibiotics                                    │
│  → Supportive care                                │
│                                                  │
│  BRONCHIOLITIS                                   │
│  → Supportive care                                │
│  → Oxygen                                         │
│                                                  │
│  CROUP                                           │
│  → Steroids (dexamethasone)                      │
│  → Nebulized adrenaline if severe                │
│                                                  │
│  OTHER                                           │
│  → Treat as appropriate                           │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         VENTILATION (IF NEEDED)                   │
│  • If respiratory failure                         │
│  • If exhausted                                    │
│  • If SpO2 &lt;92% despite oxygen                   │
│  • May need CPAP, BiPAP, or intubation            │
└─────────────────────────────────────────────────┘
                    ↓
┌─────────────────────────────────────────────────┐
│         MONITOR & FOLLOW-UP                       │
│  • Monitor work of breathing                       │
│  • Monitor SpO2                                    │
│  • Reassess severity                               │
│  • Discharge when stable                           │
└─────────────────────────────────────────────────┘

Acute/Emergency Management - The First Hour

Immediate Actions (Do Simultaneously):

  1. ABCs (Airway, Breathing, Circulation) - PRIORITY

    • Airway: Secure if compromised
    • Breathing: Assess work of breathing, auscultate
    • SpO2: Check immediately
    • Action: This is the priority
  2. Oxygen (Urgent)

    • High-flow oxygen: Give immediately
    • Don't wait: Even before you know the cause
    • Monitor SpO2: Target >92%
    • Action: Support oxygenation
  3. Identify Cause

    • History: Recent illness, known conditions
    • Examination: Auscultation, look for cause
    • Chest X-ray: If needed
    • Action: Guide treatment
  4. Treat Underlying Cause

    • Asthma: Bronchodilators, steroids
    • Pneumonia: Antibiotics
    • Bronchiolitis: Supportive care
    • Croup: Steroids, nebulized adrenaline if severe
    • Other: As appropriate
    • Action: Address cause
  5. Ventilation (If Needed)

    • If respiratory failure: May need CPAP, BiPAP, or intubation
    • If exhausted: May need ventilation
    • Action: Support breathing if needed

Medical Management

Oxygen (Essential):

MethodIndicationNotes
High-flow oxygenAll casesGive immediately
CPAPIf moderate-severeNon-invasive support
BiPAPIf moderate-severeNon-invasive support
IntubationIf respiratory failureInvasive ventilation

Asthma Treatment (If Asthma):

DrugDoseRouteNotes
Salbutamol2.5-5mgNebulizedRepeat as needed
Prednisolone1-2mg/kg (max 40mg)PODaily for 3-5 days

Pneumonia Treatment (If Pneumonia):

DrugDoseRouteNotes
Amoxicillin50mg/kg (max 1g)POTDS (if mild)
Co-amoxiclav30mg/kg (max 1.2g)IVTDS (if severe)

Croup Treatment (If Croup):

DrugDoseRouteNotes
Dexamethasone0.15mg/kg (max 10mg)PO/IMSingle dose
Nebulized adrenaline5ml of 1:1000NebulizedIf severe

Disposition

Admit to Hospital If:

  • Moderate-severe: Needs monitoring, treatment
  • ICU: If respiratory failure, needs ventilation
  • Regular ward: If stable but needs monitoring

Discharge Criteria:

  • Stable: No respiratory distress
  • SpO2 normal: On room air or low-flow oxygen
  • Able to take oral: If medications needed
  • Clear plan: For continued treatment, follow-up

Follow-Up:

  • Most recover: With appropriate treatment
  • If asthma: Ongoing asthma management
  • Long-term: Usually no long-term issues if treated promptly

8. Complications

Immediate (Hours-Days)

ComplicationIncidencePresentationManagement
Respiratory failure5-10% (if severe)Inability to breathe adequatelyVentilation
Respiratory arrest1-5% (if severe)Stopped breathingResuscitation, ventilation
Death<1% (with treatment)If not treated promptlyPrevention through early treatment
PneumothoraxRareCollapsed lungDrainage

Respiratory Failure:

  • Mechanism: Inability to breathe adequately
  • Management: Ventilation (CPAP, BiPAP, or intubation)
  • Prevention: Early recognition, treatment

Early (Days-Weeks)

1. Usually Full Recovery (90-95%)

  • Mechanism: Most recover with treatment
  • Management: Usually no long-term treatment needed
  • Prevention: Early treatment

2. Persistent Issues (5-10%)

  • Mechanism: If underlying cause persists (asthma, etc.)
  • Management: Ongoing management
  • Prevention: Address underlying cause

Late (Months-Years)

1. Usually No Long-Term Issues (90-95%)

  • Mechanism: Most recover completely
  • Management: Usually no long-term treatment needed
  • Prevention: N/A

9. Prognosis & Outcomes

Natural History (Without Treatment)

Untreated Respiratory Distress:

  • High risk of respiratory failure: Almost certain if severe
  • High mortality: If not treated promptly
  • Poor outcomes: If not treated

Outcomes with Treatment

VariableOutcomeNotes
Recovery90-95%Most recover with prompt treatment
Mortality<1%Very low with prompt treatment
Time to recoveryHours to daysWith treatment

Factors Affecting Outcomes:

Good Prognosis:

  • Early treatment: Better outcomes
  • Mild-moderate: Usually recover quickly
  • Treatable cause: Better outcomes
  • No complications: Better outcomes

Poor Prognosis:

  • Delayed treatment: Higher risk of respiratory failure
  • Severe distress: Higher risk of respiratory failure
  • Respiratory failure: Higher mortality
  • Very young: May have worse outcomes

Prognostic Factors

FactorImpact on PrognosisEvidence Level
Early treatmentBetter outcomesHigh
SeverityMore severe = worseHigh
CauseSome causes worseModerate
AgeVery young = worseModerate

10. Evidence & Guidelines

Key Guidelines

1. BTS Guidelines (2019) — British guideline on the management of asthma. British Thoracic Society

Key Recommendations:

  • Oxygen for all
  • Bronchodilators for asthma
  • Steroids for asthma
  • Evidence Level: 1A

2. NICE Guidelines (2015) — Bronchiolitis in children: diagnosis and management. National Institute for Health and Care Excellence

Key Recommendations:

  • Supportive care
  • Oxygen if needed
  • Evidence Level: 1A

Landmark Trials

Multiple studies on asthma treatment, oxygen use.

Evidence Strength

InterventionLevelKey EvidenceClinical Recommendation
Oxygen1AUniversalEssential
Bronchodilators (asthma)1AMultiple RCTsEssential for asthma
Steroids (asthma)1AMultiple RCTsEssential for asthma

11. Patient/Layperson Explanation

What is Respiratory Distress?

Respiratory distress is when your child has difficulty breathing or isn't breathing well enough. Think of breathing as your child's body getting oxygen in and carbon dioxide out—when something interferes with this (blocked airways, lung problems, weak breathing muscles), your child has to work harder to breathe, causing respiratory distress.

In simple terms: Your child is having trouble breathing and needs help. This is a medical emergency, but with prompt treatment, most children recover completely.

Why does it matter?

Respiratory distress is a medical emergency that can progress rapidly to respiratory failure (inability to breathe adequately) and death if not treated promptly. Early recognition and treatment (oxygen, treating the cause) are essential. The good news? With prompt treatment, most children recover completely.

Think of it like this: It's like your child struggling to breathe—they need urgent help, but with the right treatment, they usually recover quickly.

How is it treated?

1. Immediate Care (Most Important):

  • Oxygen: Your child will get oxygen immediately to help them breathe
  • Why: To support their breathing while we treat the cause
  • Don't wait: Even before we know exactly what's causing it

2. Identify the Cause:

  • Examination: Your doctor will examine your child to find out what's causing the breathing difficulty
  • Tests: Your child may have tests (chest X-ray, etc.) if needed
  • Why: To guide the right treatment

3. Treat the Cause:

  • If asthma: Your child will get medicines to open the airways (bronchodilators) and reduce inflammation (steroids)
  • If pneumonia: Your child will get antibiotics
  • If bronchiolitis: Your child will get supportive care and oxygen
  • If croup: Your child will get steroids
  • If other causes: Treated as appropriate

4. Support Breathing (If Needed):

  • If very severe: Your child may need help breathing (CPAP, BiPAP, or a breathing tube)
  • Why: To support their breathing if they can't breathe well enough on their own
  • When: If they're in respiratory failure or exhausted

The goal: Support your child's breathing (oxygen, ventilation if needed) and treat whatever's causing the breathing difficulty.

What to expect

Recovery:

  • Most cases: Start improving within hours with treatment
  • Symptoms: Should improve as the cause is treated
  • Full recovery: Most children recover completely within days

After Treatment:

  • Oxygen: Your child will continue to get oxygen until they can breathe well on their own
  • Medications: Your child may need medications (depending on the cause)
  • Monitoring: Close monitoring until your child is stable
  • Going home: When your child is stable and breathing well

Recovery Time:

  • Mild cases: Usually recover within hours
  • Moderate cases: Usually recover within days
  • Severe cases: May take longer, may need more support

When to seek help

Call 999 (or your emergency number) immediately if:

  • Your child is having difficulty breathing
  • Your child is breathing very fast
  • Your child's skin is blue (cyanosis)
  • Your child is very unwell
  • Your child is exhausted from breathing
  • You're very worried about your child

See your doctor if:

  • Your child seems to be working hard to breathe
  • Your child is breathing faster than normal
  • Your child has symptoms that concern you
  • You're worried about your child

Remember: If your child is having difficulty breathing, especially if they're breathing very fast, working hard to breathe, or their skin is blue, call 999 immediately. Respiratory distress is a medical emergency, but with prompt treatment, most children recover completely. Trust your instincts—if you're worried, seek help immediately.


12. References

Primary Guidelines

  1. British Thoracic Society. British guideline on the management of asthma. BTS/SIGN. 2019.

  2. National Institute for Health and Care Excellence. Bronchiolitis in children: diagnosis and management. NICE guideline [NG9]. 2015.

Key Trials

  1. Multiple studies on asthma treatment, oxygen use.

Further Resources

  • BTS Guidelines: British Thoracic Society
  • NICE Guidelines: National Institute for Health and Care Excellence

Last Reviewed: 2025-12-25 | MedVellum Editorial Team


Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. Clinical decisions should account for individual patient circumstances. Always consult appropriate specialists. This information is not a substitute for professional medical advice, diagnosis, or treatment.

Last updated: 2025-12-25

At a Glance

EvidenceHigh
Last Updated2025-12-25
Emergency Protocol

Red Flags

  • Severe respiratory distress
  • Respiratory failure
  • Signs of exhaustion
  • Cyanosis
  • Altered mental status
  • Signs of impending respiratory arrest

Clinical Pearls

  • **"Infants show different signs"** — Infants may show subtle signs (grunting, nasal flaring, poor feeding) rather than obvious difficulty breathing. Always look for these signs in infants.
  • **"Don't wait for cyanosis"** — Cyanosis is a late sign. If a child is cyanotic, they're in severe respiratory failure. Treat before they become cyanotic.
  • **"Respiratory distress can progress rapidly"** — Children, especially infants, can deteriorate very quickly. Don't wait—if you suspect respiratory distress, assess and treat urgently.
  • **Red Flags — Immediate Escalation Required:**
  • - **Severe respiratory distress** — Medical emergency, needs urgent support

Guidelines

  • NICE Guidelines
  • BTS Guidelines
  • RCUK Guidelines