Psychiatry
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Self-Harm in Adults

Comprehensive evidence-based guide to assessment and management of intentional self-injury in adults, with or without suicidal intent

Updated 9 Jan 2025
Reviewed 17 Jan 2026
36 min read
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MedVellum Editorial Team
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MedVellum Medical Education Platform

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Clinical reference article

Self-Harm in Adults

Quick Reference

Critical Alerts

Critical Alert: SAFETY FIRST: Medical stabilization takes priority. Treat overdose, wounds, and poisoning before psychiatric evaluation.

Critical Alert: UNIVERSAL ASSESSMENT: Every patient presenting with self-harm requires formal suicide risk assessment—do not assume non-suicidal intent based on method or appearance.

Critical Alert: DIRECT QUESTIONING: Asking directly about suicidal thoughts does NOT increase risk of suicide. Evidence consistently demonstrates that asking reduces distress and facilitates help-seeking. [1]

Critical Alert: HIGH-RISK OBSERVATION: Patients assessed as high risk require continuous 1:1 observation until comprehensive psychiatric evaluation is completed.

Critical Alert: MEANS RESTRICTION: Actively counsel on restricting access to lethal means—this is one of the most effective suicide prevention interventions. [2]

Key Risk Factors for Suicide Following Self-Harm

CategoryHigh-Risk Factors
HistoricalPrior suicide attempt (strongest predictor), psychiatric diagnosis, family history of suicide, childhood trauma/abuse
ClinicalHopelessness, current intoxication, severe insomnia, psychomotor agitation, command hallucinations, anhedonia
SituationalRecent significant loss, social isolation, unemployment, relationship breakdown, access to lethal means
DemographicMale sex, older age (> 65), living alone, chronic medical illness

Emergency Intervention by Risk Level

Risk LevelClinical FeaturesIntervention
Imminent/HighActive plan with access, recent high-lethality attempt, command hallucinations, severe hopelessness1:1 observation, secure environment, psychiatric admission (voluntary or involuntary)
ModerateSuicidal ideation without imminent plan, some protective factors, engaged with assessmentClose observation, psychiatric consultation, possible discharge with comprehensive safety plan
LowerPassive ideation, strong protective factors, engaged in treatment, safe environmentPsychosocial assessment, safety planning, enhanced outpatient follow-up within 48-72 hours
Medical EmergencyOverdose, significant wounds, altered consciousnessImmediate medical stabilization; psychiatric assessment when medically stable

Overview

Self-harm refers to intentional self-inflicted injury regardless of suicidal intent. This encompasses a spectrum from non-suicidal self-injury (NSSI)—where the intent is emotional regulation rather than death—to suicide attempts with clear intent to die. Understanding this distinction is clinically important but should never lead to underestimation of risk, as NSSI independently increases future suicide risk. [3]

Self-harm represents a major public health concern. Globally, approximately 800,000 people die by suicide annually, making it the 10th leading cause of death in high-income countries. [4] Hospital presentations for self-harm have increased substantially, with emergency department visits for intentional self-harm rising by over 40% in the past two decades. [5] The lifetime prevalence of NSSI is approximately 17% among adolescents and 5-6% among adults, while lifetime prevalence of suicide attempts is 2.7% globally. [6]

The assessment and management of self-harm requires a comprehensive biopsychosocial approach. Beyond immediate medical management of injuries or overdose, the clinician must conduct thorough risk assessment, identify underlying psychiatric conditions, address psychosocial stressors, and implement evidence-based interventions including safety planning and connection to appropriate ongoing care. [7]


Definition and Terminology

Core Definitions

Self-harm is defined as intentional self-poisoning or self-injury, irrespective of the apparent purpose of the act. This term is preferred in UK and European literature as it avoids assumptions about intent. [8]

Non-suicidal self-injury (NSSI) refers to the deliberate, self-inflicted destruction of body tissue without suicidal intent and for purposes not socially sanctioned. Common methods include cutting, burning, hitting, and scratching. NSSI is included as a condition for further study in DSM-5. [9]

Suicidal ideation (SI) encompasses thoughts about ending one's own life, ranging from passive wishes ("I wish I were dead") to active planning with intent and method.

Terminology Table

TermDefinitionClinical Significance
Passive suicidal ideationWishes to be dead without active consideration of methods ("I wish I didn't wake up")Lower immediate risk but requires assessment; indicates significant distress
Active suicidal ideationActive thoughts of killing oneself, with or without specific planHigher risk; assess for plan, intent, access to means
Suicide planSpecific method, time, and/or place identifiedSignificantly elevated risk; assess for preparatory behaviors
Suicide intentSubjective expectation or wish that a self-destructive act will result in deathCritical determinant of risk level
Suicide attemptSelf-directed, potentially injurious behavior with at least some intent to dieStrongest predictor of future completed suicide
Interrupted attemptPerson is interrupted by external circumstances before injury occursAssess as high risk; evaluate access to means
Aborted attemptPerson begins to take steps but stops themselvesMay indicate ambivalence; comprehensive assessment needed
Suicide gestureBehavior with low lethality, ambiguous intent (term now discouraged)Avoid minimizing language; all self-harm increases risk

Clinical Pearl: The terms "parasuicide," "deliberate self-harm," and "suicide gesture" are falling out of favor as they may minimize the clinical significance of self-harm. The preferred terminology is "self-harm" with explicit assessment of intent. [8]


Epidemiology

Prevalence and Incidence

Self-harm is substantially more common than completed suicide, representing a significant burden on emergency and mental health services. Data from the Multicentre Study of Self-Harm in England demonstrate an incidence of approximately 400 per 100,000 population per year presenting to hospital. [10]

MeasureValuePopulationSource
Hospital presentations for self-harm400 per 100,000/yearUK adults[10]
Lifetime prevalence of NSSI5.5%General adult population[6]
Lifetime prevalence of suicide attempt2.7%Global[6]
Repetition rate within 1 year15-25%Following self-harm presentation[11]
Suicide within 1 year of self-harm1-2%Following hospital presentation[12]
Lifetime suicide following self-harm3-7%Long-term follow-up[12]

Demographics

Sex differences: Females present to hospital for self-harm at approximately 1.5 times the rate of males. However, males account for approximately 75% of completed suicides. This "gender paradox" reflects differences in method choice, with males more commonly using high-lethality methods. [4]

Age distribution: Peak rates of self-harm presentation occur in females aged 15-24 years and males aged 25-34 years. Suicide rates increase with age, particularly in males, with the highest rates in those aged over 75 years. [4]

Socioeconomic factors: Self-harm rates are strongly associated with social deprivation, unemployment, and lower educational attainment. Rates are approximately three times higher in the most deprived areas compared to the least deprived. [10]

Hospital presentations for self-harm have increased substantially over the past two decades. Data from the UK Multicentre Study demonstrate a 73% increase in self-harm presentations among young females aged 16-24 years between 2000 and 2014. [13] More recent data suggest continued increases, particularly during and following the COVID-19 pandemic. [5]


Aetiology and Risk Factors

Biopsychosocial Framework

Self-harm results from complex interactions between biological vulnerabilities, psychological factors, and social/environmental stressors.

Biological Factors

FactorEvidenceMechanism
Serotonergic dysfunctionReduced 5-HIAA in CSF, altered serotonin transporter bindingImpulsivity, aggression, mood dysregulation
HPA axis dysregulationBlunted cortisol response, elevated baseline cortisolStress response abnormalities
Genetic factorsFamily studies demonstrate heritability of 30-50%Likely polygenic with gene-environment interactions
NeuroinflammationElevated inflammatory markers (IL-6, CRP)Potential link between physical and mental health

Exam Detail: Neurobiological Correlates

Neuroimaging studies have identified structural and functional abnormalities in individuals with suicidal behavior:

  • Prefrontal cortex: Reduced gray matter volume and activity, associated with impaired decision-making and impulse control
  • Amygdala: Heightened reactivity to negative emotional stimuli
  • Anterior cingulate cortex: Abnormalities in error monitoring and conflict resolution
  • Orbitofrontal cortex: Altered reward processing and behavioral inhibition

The serotonergic system is most strongly implicated, with reduced serotonin transporter binding and blunted serotonin synthesis capacity. This may underlie the impulsivity and aggression associated with suicidal behavior. [14]

Psychological Factors

FactorDescriptionClinical Relevance
HopelessnessNegative expectations about the futureStronger predictor than depression alone; assess directly
Psychological pain (psychache)Unbearable psychological sufferingCore driver; reducing pain is therapeutic target
Cognitive rigidityInability to generate alternative solutions"Tunnel vision"; cognitive therapy targets this
PerfectionismSelf-critical perfectionism, perceived failureCommon in high-achieving individuals
Poor distress toleranceInability to tolerate negative emotional statesTarget of DBT skills training
Emotional dysregulationDifficulty modulating emotional responsesCore feature of NSSI function

Social and Environmental Factors

FactorImpactEvidence Level
Childhood trauma/abuse2-5x increased riskStrong
Recent significant lossRelationship, employment, bereavementStrong
Social isolationLack of connectedness, living aloneStrong
Financial difficultiesDebt, unemployment, housing insecurityModerate
Access to lethal meansParticularly firearms, medicationsStrong
Media exposureContagion effects, especially in young peopleModerate
Social mediaCyberbullying, exposure to self-harm contentEmerging

Psychological Models

Interpersonal Theory of Suicide (Joiner)

This influential model proposes that suicide capability requires the simultaneous presence of: [15]

  1. Thwarted belongingness: Unmet need for social connectedness ("I am alone")
  2. Perceived burdensomeness: Belief that one is a burden on others ("I am a burden")
  3. Acquired capability: Reduced fear of death and elevated pain tolerance, often acquired through repeated exposure to painful or provocative experiences (including NSSI)

Clinical Pearl: NSSI may contribute to "acquired capability" for suicide by habituating the individual to self-inflicted pain and injury. This is one mechanism by which NSSI increases future suicide risk, even in the absence of initial suicidal intent.

Integrated Motivational-Volitional Model (O'Connor)

This three-phase model describes the pathway to suicidal behavior: [16]

  1. Pre-motivational phase: Background factors and triggering events
  2. Motivational phase: Development of suicidal ideation through defeat/entrapment perceptions
  3. Volitional phase: Transition from ideation to action, moderated by capability factors

This model emphasizes that most people with suicidal ideation do not attempt suicide—understanding factors that facilitate transition to action is crucial.

Psychiatric Comorbidity

The vast majority of individuals who die by suicide have a diagnosable psychiatric disorder. Key associations include:

DisorderRelative Risk for SuicideKey Features
Major Depressive Disorder20xHopelessness, anhedonia, sleep disturbance
Bipolar Disorder20-30xMixed states, depressive episodes, impulsivity
Schizophrenia8-10xCommand hallucinations, early illness, post-discharge
Borderline Personality Disorder45xChronic suicidality, NSSI, emotional dysregulation
Alcohol Use Disorder5-10xIntoxication increases impulsivity; withdrawal states
Substance Use Disorder7xPolysubstance use, opioid use disorder
Anorexia Nervosa30xHighest mortality of any psychiatric disorder
PTSD4-6xParticularly with comorbid depression

Methods of Self-Harm

Overview of Methods

The method of self-harm provides important clinical information but should not be used to infer suicidal intent or predict future risk. Method availability strongly influences choice. [17]

MethodProportion of PresentationsLethalityKey Considerations
Self-poisoning70-80%VariableMost common ED presentation; acetaminophen, NSAIDs, antidepressants most frequent
Cutting20-25%Usually lowMost common NSSI method; forearms, thighs typical locations
Hanging/strangulation2-5%HighHigh lethality; associated with completed suicide
Jumpingless than 1%HighAccess to height is key modifiable factor
Firearmless than 1% (UK); 50% (US suicides)Very highMost lethal method; access is critical factor
Burning1-2%VariableMay indicate severe psychopathology
Head-banging/hitting5-10%Usually lowCommon in developmental disorders, acute distress

Self-Poisoning (Overdose)

Self-poisoning accounts for the majority of hospital presentations for self-harm. Common substances include:

Medications:

  • Acetaminophen (paracetamol): Most common; serious hepatotoxicity risk
  • Non-steroidal anti-inflammatory drugs
  • Antidepressants (particularly TCAs, SSRIs in combination)
  • Benzodiazepines
  • Opioids (increasingly common)
  • Antipsychotics

Other substances:

  • Alcohol (often in combination)
  • Illicit drugs
  • Household products

Critical Alert: STAGGERED OVERDOSE: Patients may take multiple doses over several hours or days. This pattern is associated with worse outcomes in acetaminophen poisoning and requires specific management protocols.

Non-Suicidal Self-Injury (NSSI)

NSSI serves specific psychological functions, most commonly: [9]

  1. Affect regulation: Rapid relief from intense negative emotions (most common)
  2. Self-punishment: Response to self-directed anger or guilt
  3. Anti-dissociation: Generation of feeling when experiencing numbing/depersonalization
  4. Interpersonal influence: Communication of distress (less common than perceived)
  5. Sensation-seeking: In context of emotional numbness

Common methods and locations:

  • Cutting: Forearms, thighs, abdomen
  • Burning: Cigarettes, heated objects
  • Scratching/picking: Arms, hands
  • Hitting/banging: Head, limbs against hard surfaces

Clinical Pearl: Understanding the function of NSSI guides treatment. If the primary function is affect regulation, treatment focuses on developing alternative emotion regulation strategies (central to DBT). If the function is anti-dissociative, grounding techniques are prioritized.


Clinical Presentation

History Taking

A comprehensive psychiatric history is essential. Key domains include:

Presenting Episode

About the self-harm act:

  • What method(s) were used?
  • What was the timing and sequence of events?
  • Where did it occur and who was present?
  • Was there planning or was it impulsive?
  • Were precautions taken against discovery?
  • Did they seek help afterward or expect to be discovered?
  • What substances were involved (type, quantity, timing)?

About intent:

  • "Did you want to die?"
  • "Did you expect to die?"
  • "Are you disappointed to have survived?"
  • "What did you hope would happen?"
  • "What, if anything, stopped you from doing more?"

About current mental state:

  • Ongoing suicidal ideation?
  • Current plan or intent?
  • Reasons for living vs. reasons for dying?
  • Hopelessness about the future?

Current Suicidal Ideation

Use structured questioning to assess:

DomainKey Questions
Frequency"How often do you have thoughts about ending your life?"
Intensity"How strong are these thoughts?"
Duration"How long do these thoughts last?"
Controllability"Can you dismiss these thoughts or do they take over?"
Plan"Have you thought about how you would do it?"
Access to means"Do you have access to [method]? Are there firearms/medications at home?"
Preparatory behaviors"Have you done anything to prepare—giving things away, writing notes?"
Deterrents"What stops you from acting on these thoughts?"

Psychiatric History

  • Previous self-harm or suicide attempts (strongest predictor)
  • Psychiatric diagnoses and hospitalizations
  • Current treatment and medication
  • Engagement with mental health services
  • History of trauma or abuse

Medical History

  • Chronic medical conditions (pain, disability, terminal illness)
  • Recent diagnoses or health deterioration
  • Medications (assess lethality of available medications)

Substance Use

  • Alcohol: Current intoxication, dependence, recent changes
  • Drugs: Type, frequency, recent use
  • Prescription medication misuse

Social History

  • Living situation and social supports
  • Employment/financial status
  • Relationships and recent losses
  • Access to lethal means (firearms, medications)
  • Children or dependents

Mental State Examination

Systematic mental state examination is essential:

DomainKey Observations
AppearanceEvidence of self-harm wounds (old/new), self-neglect, intoxication
BehaviorAgitation, retardation, eye contact, engagement
SpeechRate, volume, tone (flat, monotonous may indicate depression)
MoodSubjective: "How would you describe your mood?"
AffectObjective: Range, reactivity, congruence
Thought contentSuicidal ideation, hopelessness, worthlessness, guilt
PerceptionsHallucinations, particularly command auditory hallucinations
CognitionOrientation, concentration (may indicate intoxication, delirium)
InsightUnderstanding of illness, need for treatment
JudgmentAbility to make safe decisions

Critical Alert: COMMAND HALLUCINATIONS: Always specifically ask about voices commanding self-harm or suicide. Patients may not volunteer this information. Command hallucinations with perceived malevolent identity and history of acting on commands confer highest risk.

Physical Examination

General assessment:

  • Vital signs (tachycardia, hypotension, fever may indicate toxicity)
  • Level of consciousness (GCS)
  • Pupil size and reactivity
  • Signs of intoxication
  • Evidence of trauma

Wound assessment for cutting/self-injury:

FeatureAssessmentClinical Significance
LocationForearms, thighs, abdomen common for NSSIHidden locations may indicate secrecy
DepthSuperficial, dermal, subcutaneous, tendon/vessel involvementDeeper wounds require surgical assessment
NumberSingle vs. multiple; old vs. newChronicity pattern
PatternParallel lines, words, randomMay indicate specific pathology
Healing stageFresh, healing, scarredEvidence of chronicity

Signs suggestive of significant overdose:

  • Altered mental status
  • Respiratory depression
  • Tachycardia or bradycardia
  • Hypotension or hypertension
  • Seizures
  • Hepatic tenderness (acetaminophen)
  • Nystagmus, ataxia (anticonvulsants)

Red Flags

Features Indicating High Suicide Risk

Critical Alert: The following features indicate HIGH or IMMINENT suicide risk and typically warrant psychiatric admission:

Red FlagWhy It Matters
Active plan with access to lethal meansImminent risk; capability is present
Recent high-lethality attemptMethod lethality correlates with future risk
Disappointment at survivalIntent persists; ambivalence absent
Command auditory hallucinations to harm selfCompelling force to act; reduced volition
Severe hopelessness with no reasons for livingHopelessness is strongest cognitive predictor
Current intoxication with suicidal ideationIntoxication disinhibits and increases impulsivity
Recent discharge from psychiatric inpatient unitHighest risk period is first 2 weeks post-discharge
Social isolation with no supportsNo external protective factors
Preparatory behaviorsGiving possessions away, writing notes, putting affairs in order
Recent significant lossRelationship breakdown, bereavement, job loss
History of multiple prior attemptsEach attempt increases future risk

Protective Factors

Protective factors may mitigate risk but should never lead to dismissal of concerning features:

Protective FactorConsideration
Strong social supportFamily, friends actively involved
Children or dependentsResponsibility, connection
Engaged in treatmentTherapeutic alliance, help-seeking
Future-oriented plansGoals, upcoming events
Religious/moral objectionsMay prevent action despite ideation
No access to lethal meansReduced capability
Ambivalence about deathSome wish to live
Fear of death or painBarrier to action

Differential Diagnosis

Primary Considerations

ConditionFeaturesKey Differentiators
Major Depression with suicidal ideationLow mood, anhedonia, neurovegetative symptomsPervasive hopelessness, suicidal ideation typical
Borderline Personality DisorderChronic NSSI, emotional dysregulation, interpersonal instabilityRecurrent pattern, impulsive self-harm, affect regulation function
Psychotic disorder with command hallucinationsActing on voices, bizarre ideationAssess for hallucinations; may lack apparent "reason"
Bipolar disorder (mixed or depressive episode)Agitation, mood instability, impulsivityMixed states particularly high risk
Substance use disorderIntoxication, withdrawal, impulsivityReassess when sober; address comorbidity
Adjustment disorderClear precipitant, time-limited distressIdentifiable stressor, preserved functioning otherwise
PTSDTrauma-related distress, flashbacks, avoidanceNSSI may be trauma-related coping mechanism

Other Considerations

ConditionFeatures
DeliriumConfusion, fluctuating consciousness; self-harm may be accidental or secondary to disorientation
DementiaCognitive impairment; self-harm may occur during behavioral disturbance
Factitious disorderSelf-inflicted injuries to assume sick role; denial of self-causation
Accidental overdoseDenies suicidal intent; assess carefully for minimization
MalingeringExternal incentive (avoid incarceration, obtain housing); rare

Clinical Pearl: Patients with personality disorders who present repeatedly with self-harm are sometimes dismissed as "not really suicidal." This is dangerous—the suicide rate in borderline personality disorder is 8-10%, and repeated NSSI is a strong risk factor for eventual completed suicide.


Investigations

Medical Assessment

All patients presenting with self-harm require medical evaluation to exclude toxicity or injury requiring treatment.

Mandatory for All Overdoses

InvestigationIndicationKey Values
Blood glucoseAltered consciousnessRule out hypoglycemia
Acetaminophen levelAll overdoses (even if denied)Plot on Rumack-Matthew nomogram at ≥4 hours
Salicylate levelAll overdosesToxic > 300 mg/L; severe > 700 mg/L
Urea, creatinine, electrolytesBaseline renal function; overdose assessmentElectrolyte disturbance, renal toxicity
Liver function testsHepatotoxic ingestion (acetaminophen, others)ALT/AST elevation indicates hepatic injury
ECGCardiotoxic drugs (TCAs, antipsychotics, antiarrhythmics)QRS prolongation, QTc prolongation, arrhythmia
Blood alcohol levelSuspected intoxicationMay affect capacity assessment

Additional Investigations Based on Presentation

InvestigationIndication
Urine drug screenSuspected substance use; clinical features unexplained
Arterial blood gasSignificant overdose, altered consciousness, respiratory concerns
Coagulation studiesAnticoagulant ingestion, hepatic damage
Creatine kinaseProlonged immobility, muscle damage
Venous lactateMetformin ingestion, tissue hypoxia
CT headHead injury, unexplained altered consciousness

Psychiatric Assessment Tools

Columbia Suicide Severity Rating Scale (C-SSRS)

The C-SSRS is a validated, structured interview tool for assessing suicide risk. It assesses: [1]

  • Severity of ideation (5 levels from passive to active with intent and plan)
  • Intensity of ideation (frequency, duration, controllability)
  • Suicidal behavior (actual attempts, interrupted/aborted attempts, preparatory behaviors)

Clinical Pearl: The C-SSRS provides standardized language and structure for suicide risk assessment. It is freely available and widely recommended in emergency settings.

Other Validated Tools

ToolUseLimitations
Beck Hopelessness ScaleQuantify hopelessnessSelf-report; may underreport
Patient Health Questionnaire-9 (PHQ-9)Depression severity; item 9 screens for self-harmBrief screen only
SAD PERSONS scaleMnemonic risk assessmentPoor predictive validity; not recommended alone
Manchester Self-Harm RulePredict repetition riskClinical decision support, not replacement

Critical Alert: LIMITATIONS OF TOOLS: No risk assessment tool can accurately predict suicide at an individual level. Scales should inform—not replace—comprehensive clinical assessment. Over-reliance on tools may lead to false reassurance or false alarm.


Psychosocial Assessment

NICE Guidance

NICE Clinical Guideline 16 recommends that all individuals presenting with self-harm receive a comprehensive psychosocial assessment, ideally within 48 hours and certainly before discharge. [8]

This assessment should include:

  1. Circumstances of the self-harm
  2. Current suicidal intent and mental state
  3. Hopelessness
  4. Psychiatric history and diagnosis
  5. Social circumstances and supports
  6. Personal resources and coping strategies
  7. Risk of further self-harm or suicide
  8. Need for ongoing treatment and appropriate setting

Structured Approach

DomainKey Elements to Assess
Current episodeMethod, planning, intent, lethality, chance of discovery, attitude to survival
Mental stateDepression, psychosis, anxiety, intoxication, hopelessness
Psychiatric historyDiagnoses, previous self-harm, treatment history
Personal historyTrauma, abuse, losses, personality difficulties
Current circumstancesRelationships, living situation, employment, stressors
Coping resourcesPrevious strategies, supports, protective factors
Risk formulationIntegration of risk and protective factors; clinical judgment

Risk Assessment and Formulation

Principles of Risk Assessment

Risk assessment is a clinical process, not a bureaucratic checkbox exercise. The goal is to understand the individual's current state and develop a management plan that addresses modifiable risk factors.

Key principles:

  1. Risk is dynamic: Risk changes over time and with circumstances
  2. Risk is contextual: Environmental factors (means access, supports) are crucial
  3. Prediction is limited: Focus on reducing modifiable factors, not predicting the unpredictable
  4. Documentation is essential: Record reasoning, not just risk level label

Risk Stratification

LevelFeaturesManagement Considerations
High/ImminentActive intent, plan, access to means; recent high-lethality attempt; severe hopelessness; psychosis with command hallucinations; no protective factorsPsychiatric admission (voluntary or involuntary); 1:1 observation; secure environment
ModerateSuicidal ideation without clear intent/plan; some protective factors; underlying treatable condition; some engagementPsychiatric consultation; consider admission vs. comprehensive community plan; close follow-up
LowerPassive ideation only; strong protective factors; no plan/intent; engaged in treatment; safe environmentSafety planning; enhanced outpatient follow-up within 72 hours; means counseling

Clinical Pearl: Risk stratification is a communication tool and guide to intensity of intervention—not a prediction of outcome. A patient rated "low risk" may still complete suicide; a "high risk" patient may not. Document the reasoning behind your formulation.

Risk Formulation

A risk formulation synthesizes the assessment into a coherent narrative that explains the individual's current state and guides management.

Components:

  1. Predisposing factors: What made this person vulnerable? (e.g., childhood trauma, family history, personality traits)
  2. Precipitating factors: What triggered this episode? (e.g., relationship breakdown, job loss)
  3. Perpetuating factors: What is keeping them at risk? (e.g., ongoing depression, hopelessness, social isolation)
  4. Protective factors: What may prevent further self-harm? (e.g., children, engaged in treatment, future plans)
  5. Risk level and rationale: Synthesis of above; explicit statement of reasoning
  6. Management plan: What will be done to address modifiable factors

Management

Principles

  1. Medical stabilization first: Treat overdose, wounds, poisoning before psychiatric assessment
  2. Compassionate, non-judgmental care: Stigmatizing attitudes worsen outcomes and reduce help-seeking
  3. Comprehensive assessment: Every patient deserves thorough evaluation
  4. Least restrictive intervention: Balance safety with autonomy
  5. Address underlying causes: Treat psychiatric illness, address psychosocial stressors
  6. Means restriction: Reduce access to lethal methods
  7. Continuity of care: Seamless transition from emergency to ongoing care

Acute Medical Management

Self-Poisoning/Overdose

Refer to specific toxicology protocols. Key principles:

InterventionIndicationNotes
Activated charcoalWithin 1 hour of ingestion (some drugs up to 2 hours)Not for hydrocarbons, alcohols, metals, corrosives
N-acetylcysteineAcetaminophen overdose per nomogramStart immediately if staggered overdose or late presentation with elevated ALT
Gastric lavageRarely indicated; large ingestion less than 1 hourOnly in protected airway
Whole bowel irrigationSustained-release formulations, body packingPolyethylene glycol solution
Specific antidotesNaloxone (opioids), flumazenil (benzodiazepines with caution), sodium bicarbonate (TCA)Follow toxicology guidance

Wound Management

Wound TypeManagement
Superficial cutsClean, assess tetanus status, wound closure if needed, safety planning
Deep lacerationsAssess tendon/neurovascular injury, surgical referral if needed
Ligature marksAssess airway, imaging if concern for vascular/laryngeal injury
BurnsStandard burn management; assess surface area and depth

Emergency Department Safety

InterventionPurpose
1:1 observationContinuous monitoring for high-risk patients
Environmental safetyRemove sharps, cords, medications from patient access
Search of belongingsPer protocol; explain rationale
Secure roomLigature-resistant if available
Elopement precautionsMonitor exits; locked unit if appropriate

Psychiatric Management

For High-Risk Patients

  • Inpatient psychiatric admission: Voluntary or involuntary under mental health legislation
  • Continuous 1:1 observation until admission
  • Psychiatry consultation for admission planning
  • Medication review: Address undertreated psychiatric illness

For Moderate-Risk Patients

Careful clinical judgment required. May consider discharge with:

  • Comprehensive safety plan
  • Strong social support engaged
  • Means restriction implemented
  • Outpatient follow-up within 24-72 hours
  • Clear crisis pathway identified
  • Underlying condition addressed (medication started/adjusted)

For Lower-Risk Patients

  • Safety planning intervention
  • Outpatient mental health referral
  • Means restriction counseling
  • Crisis resources provided
  • Follow-up within 72 hours

Safety Planning Intervention

The Safety Planning Intervention (SPI) is an evidence-based, brief intervention that reduces suicidal behavior. [18] It differs from "no-suicide contracts," which lack evidence of effectiveness.

Stanley-Brown Safety Planning Intervention Components:

StepContentExample
1. Warning signsRecognition of personal crisis triggers"When I start feeling worthless and can't stop crying"
2. Internal coping strategiesWhat can I do alone to feel better?"Take a walk, listen to music, breathing exercises"
3. Social contacts for distractionPeople/places to distract from crisis"Go to friend's house, call sister to chat about other things"
4. People to ask for helpSpecific individuals to contact in crisis"Call my partner, my best friend Sarah"
5. Professionals to contactMental health professionals, crisis services"My therapist [number], Crisis team [number], 988 (US)/Samaritans 116 123 (UK)"
6. Making the environment safeMeans restriction"Partner will lock away medications, remove firearms from home"

Clinical Pearl: Safety planning is collaborative—developed WITH the patient, not given TO them. The process of creating the plan is therapeutic. Provide a written copy and photograph for their phone.

Means Restriction

Means restriction is one of the most effective suicide prevention interventions. [2] Counsel all patients and their families on:

Medications:

  • Lock up all medications, including over-the-counter
  • Dispose of unneeded medications safely
  • Prescribe limited quantities (e.g., 1 week supply)
  • Consider blister packs rather than bottles

Firearms:

  • Most lethal method; firearm access dramatically increases suicide risk
  • Counsel on temporary removal or secure storage
  • Unloaded, locked, ammunition stored separately
  • Ideally removed from the home entirely during crisis

Other means:

  • Secure ligature points
  • Limit access to heights
  • Remove/secure sharp objects

Clinical Pearl: Means restriction works because many suicidal crises are time-limited. Introducing a barrier buys time for the crisis to pass. Substitution to other methods is less common than expected.

Pharmacotherapy

There is no medication specifically approved for acute suicidality, but treatment of underlying psychiatric conditions is essential.

Medication ClassRoleEvidence
AntidepressantsTreat underlying depressionReduce suicide risk with treatment, despite black box warning about initial increased risk in young people
LithiumMood stabilization in bipolar; specific anti-suicidal effectStrong evidence for suicide prevention in bipolar disorder [19]
ClozapineSchizophrenia with suicidalityFDA-approved for reducing suicide in schizophrenia
Ketamine/esketamineRapid reduction in suicidal ideationEmerging evidence; esketamine approved for treatment-resistant depression with suicidality

Exam Detail: Lithium's Anti-Suicidal Effect

Lithium has a specific anti-suicidal effect independent of its mood-stabilizing properties. Meta-analyses demonstrate approximately 80% reduction in suicide risk in patients with mood disorders. The mechanism may relate to serotonergic effects and reduction in impulsivity and aggression. [19]

Psychotherapy

Dialectical Behavior Therapy (DBT)

DBT is the most extensively studied treatment for individuals with borderline personality disorder and chronic self-harm. [20] It is considered the gold standard for NSSI.

Components:

  • Individual therapy
  • Skills training group (core skills: mindfulness, distress tolerance, emotion regulation, interpersonal effectiveness)
  • Phone coaching for crisis skills application
  • Therapist consultation team

Evidence: Multiple RCTs demonstrate reduced self-harm, reduced suicide attempts, and reduced hospitalization.

Other Evidence-Based Therapies

TherapyIndicationEvidence
Cognitive Behavioral Therapy (CBT)Depression, anxiety, suicidal ideationStrong evidence for depression; emerging for suicide-specific CBT
Mentalization-Based Therapy (MBT)Borderline personality disorderReduced self-harm and suicide attempts
Collaborative Assessment and Management of Suicidality (CAMS)Suicide-focused treatment frameworkEmerging evidence for reduced ideation
Brief intervention and contactPost-ED careWHO BIC reduces suicide; caring contacts effective

Disposition

Criteria for Psychiatric Admission

Critical Alert: The following features typically indicate need for inpatient psychiatric care:

IndicationRationale
Active suicidal ideation with plan and intentImminent risk requires secure environment
Recent high-lethality suicide attemptDemonstrated capability and intent
Psychosis with command hallucinations to self-harmReduced volition; compelling force to act
Severe hopelessness with no reasons for livingCore cognitive risk factor unaddressed
Inability to engage in safety planningCannot participate in outpatient risk mitigation
Inadequate social supportNo external protective factors
Acute psychiatric illness requiring stabilizationE.g., severe depression, mania, psychosis
Previous self-harm shortly after ED/hospital dischargePattern of post-discharge deterioration

Involuntary Admission

When a patient refuses voluntary admission and meets criteria for danger to self, involuntary admission under mental health legislation may be necessary.

UK (Mental Health Act 1983):

  • Section 2: Assessment (up to 28 days)
  • Section 3: Treatment (up to 6 months)
  • Section 5(2): Doctor's holding power (up to 72 hours)

Documentation requirements:

  • Evidence of mental disorder
  • Nature and degree warranting detention
  • Necessity for health, safety, or protection of others
  • Least restrictive option considered

Criteria for Discharge

Patients may be considered for discharge with community follow-up if:

CriterionDescription
No current suicidal intentIdeation may be present but no intent/plan
Adequate protective factorsSocial support, engaged with treatment, reasons for living
Means restriction in placeLethal means removed/secured
Safety plan completedCollaborative plan with patient and supports
Follow-up arrangedMental health appointment within 48-72 hours
Crisis pathway clearPatient knows how to access help
Not intoxicatedCan participate meaningfully in assessment and planning
Underlying condition addressedMedication adjusted, crisis precipitant addressed

Follow-Up

PopulationRecommended Follow-Up
Post-self-harm ED presentationWithin 48-72 hours
Post-psychiatric admissionWithin 7 days of discharge
High-risk patients in communitySame-week contact
Ongoing suicidal ideationWeekly or more frequent until stable

Clinical Pearl: The first 1-2 weeks after discharge from psychiatric inpatient care is the highest-risk period for suicide. Intensive follow-up during this transition is critical.


Special Populations

Older Adults

  • Higher lethality: More lethal methods, less likely to survive attempts
  • Less warning: May give fewer verbal warnings of intent
  • Physical illness: Chronic disease, disability, pain are risk factors
  • Social isolation: Widowhood, decreased mobility, loneliness
  • Depression often unrecognized: May present as somatic complaints

Assessment considerations: Screen for depression, assess functional status, social network, and physical health comorbidities.

LGBTQ+ Individuals

  • Elevated risk: 2-3x higher rates of suicidal ideation and attempts
  • Contributing factors: Minority stress, discrimination, family rejection, identity-related distress
  • Protective factors: Affirming environments, community connection, family acceptance

Assessment considerations: Create affirming environment, ask about gender identity and pronouns, assess for discrimination-related distress.

People with Intellectual Disabilities

  • Underrecognized: Self-harm may be attributed to challenging behavior
  • Communication difficulties: May have difficulty expressing distress
  • Increased vulnerability: Trauma, abuse, loss more common

Assessment considerations: Adapted communication, involve caregivers, assess for pain/physical causes of behavioral change.

Perinatal Period

  • Perinatal mental illness: Significant risk factor for self-harm and suicide
  • Suicide is leading cause of maternal death: In high-income countries
  • Specific considerations: Baby's welfare, bonding, support needs

Assessment considerations: Perinatal mental health team involvement, mother-baby unit consideration, safeguarding.

Substance Use Disorders

  • High comorbidity: Greatly elevated suicide risk
  • Intoxication increases impulsivity: Reassess when sober
  • Chronic use increases risk: Even when not acutely intoxicated

Assessment considerations: Assess for withdrawal, integrated mental health and substance treatment, address SUD in care plan.

Chronic Self-Harm

  • Pattern of repeated NSSI: Often in context of borderline personality disorder
  • Not "just attention seeking": NSSI confers significant suicide risk
  • Compassion fatigue in providers: Maintain non-judgmental stance

Assessment considerations: Each presentation deserves thorough assessment; DBT referral; avoid dismissive attitudes.


Patient and Family Education

For the Patient

Key messages to communicate:

  • "What you're going through is serious, and help is available."
  • "These thoughts and feelings can change with treatment and support."
  • "We've made a safety plan together—please use it when you're struggling."
  • "It's important to remove access to things that could hurt you."
  • "Please come back to the ED or call the crisis line if things get worse."

For Family/Support Persons

Key messages:

  • "Your loved one is going through a very difficult time."
  • "You can help by removing access to medications, firearms, and other means."
  • "Watch for warning signs: increased talk of death, giving things away, social withdrawal."
  • "Encourage use of the safety plan and follow-up appointments."
  • "It's OK to ask directly about suicidal thoughts—it doesn't make things worse."
  • "If you're concerned, bring them back to the ED or call the crisis line."

Crisis Resources

International:

United Kingdom:

  • Samaritans: 116 123 (24/7, free)
  • Crisis Text Line: Text SHOUT to 85258
  • Papyrus (under 35s): 0800 068 4141

United States:

  • 988 Suicide and Crisis Lifeline: Call or text 988
  • Crisis Text Line: Text HOME to 741741
  • Veterans Crisis Line: 988, press 1

Australia:

  • Lifeline: 13 11 14
  • Beyond Blue: 1300 22 4636
  • Suicide Call Back Service: 1300 659 467

Prognosis

Risk of Repetition

Following a self-harm presentation:

TimeframeRepetition RateSuicide Rate
1 year15-25%1-2%
5 years30-40%3-5%
Lifetime50%+5-10%

Factors Associated with Worse Outcome

FactorImpact
Previous suicide attemptStrongest predictor of future completed suicide
Psychiatric illnessParticularly if untreated
Substance use disorderIndependent additive risk
Social isolationLack of protective factors
Continued access to meansCapability maintained
Non-engagement with follow-upMissed opportunity for intervention

Factors Associated with Better Outcome

FactorImpact
Treatment engagementPsychotherapy, medication compliance
Strong social supportFamily, friends involved
Means restrictionReduced capability
Resolution of precipitantsRelationship, employment stabilized
Development of coping strategiesSkills to manage future crises

Quality Metrics and Documentation

Documentation Requirements

All self-harm assessments should document:

ElementContent
Presenting complaintDescription of self-harm episode
Mental state examinationSystematic MSE
Risk assessmentFactors assessed, risk level, reasoning
Protective factorsWhat mitigates risk
Capacity assessmentIf relevant to decision-making
Risk formulationSynthesis narrative
Management planSpecific interventions, follow-up
Safety planIf completed, attach/summarize
Means restrictionCounseling provided, actions taken
Crisis resourcesProvided to patient
Collateral informationSources contacted
Disposition and reasoningWhy this level of care

Quality Indicators

MetricTargetRationale
Psychosocial assessment documented100%Standard of care; NICE mandate
Safety plan provided at discharge100%Evidence-based intervention
Means restriction counseling100%Effective prevention
Follow-up appointment arranged100%Transition of care
Mental health follow-up within 7 days> 95%High-risk transition period
Risk assessment documented100%Clinical and medicolegal requirement

Key Clinical Pearls

Assessment

Clinical Pearl: Ask directly about suicide. Research consistently shows that asking about suicidal thoughts does not increase risk—it often provides relief and facilitates help-seeking. Avoiding the question due to discomfort is a missed opportunity.

Clinical Pearl: Prior suicide attempt is the strongest predictor of future completed suicide. Always ask about previous self-harm in detail: method, lethality, intent, what interrupted the attempt.

Clinical Pearl: Hopelessness is more predictive than depression severity. A patient may score "moderately" depressed but have profound hopelessness—this warrants heightened concern.

Clinical Pearl: Reassess when sober. Intoxication impairs judgment and increases impulsivity. A patient who appears high-risk while intoxicated may be lower risk when sober—but requires reassessment, not assumption.

Clinical Pearl: NSSI is not "just attention seeking". Non-suicidal self-injury confers significant risk for future suicide. Every episode deserves thorough assessment and compassionate care.

Management

Clinical Pearl: Safety planning is evidence-based; "no-suicide contracts" are not. Safety planning is collaborative, specific, and addresses capability. Contracts are passive and lack evidence of effectiveness.

Clinical Pearl: Means restriction saves lives. Counseling on means restriction (especially firearms) is one of the most effective interventions. Most crises are time-limited—barriers buy time.

Clinical Pearl: Follow-up within 72 hours is critical. The period after ED discharge or inpatient care is high-risk. Ensure clear follow-up and that the patient knows how to access help.

Clinical Pearl: Document your reasoning, not just the risk level. A risk level label without explanation is clinically and legally insufficient. Explain why you assessed risk as you did and what your plan addresses.

Disposition

Clinical Pearl: High risk = psychiatric evaluation and usually admission. When risk is high, err on the side of caution. A missed high-risk patient has catastrophic consequences.

Clinical Pearl: Involve family and supports. Engage trusted others in safety planning, means restriction, and monitoring. They are a crucial part of the safety net.


Exam-Focused Content

Common Viva Questions

  1. "A 25-year-old woman presents after cutting her forearms. How would you assess her?"
  2. "What are the key risk factors for suicide following self-harm?"
  3. "How do you distinguish between NSSI and a suicide attempt?"
  4. "What is the evidence for safety planning interventions?"
  5. "When would you consider involuntary admission for a patient with self-harm?"
  6. "What is the role of means restriction in suicide prevention?"
  7. "How do you manage a patient with chronic self-harm and borderline personality disorder?"
  8. "What are the principles of psychosocial assessment after self-harm?"

Model Viva Answer

Q: "A 35-year-old man presents to the emergency department after a paracetamol overdose. Describe your approach to assessment and management."

A: "I would approach this systematically, addressing both medical and psychiatric aspects.

Medical management first: I would assess the quantity and timing of ingestion, as this determines management. I would take blood at 4 hours post-ingestion for paracetamol level and plot this on the nomogram. If the level is above the treatment line, or if there's any doubt about timing (staggered overdose), I would commence N-acetylcysteine. I would also check LFTs, renal function, coagulation, and blood glucose. Any patient with rising ALT or coagulopathy needs urgent hepatology input.

Comprehensive psychiatric assessment: Once medically stable, I would conduct a thorough psychosocial assessment including the circumstances of the overdose, current suicidal ideation, mental state examination, psychiatric and personal history, and social circumstances. I would specifically assess intent—did he want to die? Did he expect to die? Is he disappointed to have survived?

Risk assessment: I would formulate risk by considering predisposing factors, precipitants, perpetuating factors, and protective factors. Key high-risk features would include a high-lethality method, planning, precautions against discovery, ongoing hopelessness, and lack of social support.

Management plan: Depending on risk level, I would consider psychiatric admission if risk is high. For moderate or lower risk, I would develop a collaborative safety plan, counsel on means restriction, arrange follow-up within 48-72 hours, and provide crisis contacts. I would involve family in safety planning with the patient's consent.

Documentation: I would document my assessment, risk formulation, reasoning for disposition, and the specific safety plan."

Common Mistakes in Exams

Critical Alert:Mistakes that fail candidates:

  • Assuming NSSI means "not really suicidal"
  • Failing to ask directly about suicidal ideation
  • Using "no-suicide contracts" as a management strategy
  • Discharging high-risk patients without psychiatric assessment
  • Not documenting risk assessment reasoning
  • Forgetting to counsel on means restriction
  • Assuming that intoxicated patients cannot be assessed
  • Dismissing chronic self-harmers as "attention-seeking"
  • Not arranging follow-up after ED assessment

References

  1. Posner K, Brown GK, Stanley B, et al. The Columbia-Suicide Severity Rating Scale: Initial validity and internal consistency findings from three multisite studies with adolescents and adults. Am J Psychiatry. 2011;168(12):1266-1277. doi:10.1176/appi.ajp.2011.10111704

  2. Mann JJ, Apter A, Bertolote J, et al. Suicide prevention strategies: A systematic review. JAMA. 2005;294(16):2064-2074. doi:10.1001/jama.294.16.2064

  3. Ribeiro JD, Franklin JC, Fox KR, et al. Self-injurious thoughts and behaviors as risk factors for future suicide ideation, attempts, and death: A meta-analysis of longitudinal studies. Psychol Med. 2016;46(2):225-236. doi:10.1017/S0033291715001804

  4. World Health Organization. Suicide worldwide in 2019: Global health estimates. Geneva: WHO; 2021. https://www.who.int/publications/i/item/9789240026643

  5. Carr MJ, Ashcroft DM, Kontopantelis E, et al. Premature death among primary care patients with a history of self-harm. Ann Fam Med. 2017;15(3):246-254. doi:10.1370/afm.2054

  6. Nock MK, Borges G, Bromet EJ, et al. Cross-national prevalence and risk factors for suicidal ideation, plans and attempts. Br J Psychiatry. 2008;192(2):98-105. doi:10.1192/bjp.bp.107.040113

  7. Hawton K, Witt KG, Salisbury TLT, et al. Psychosocial interventions following self-harm in adults: A systematic review and meta-analysis. Lancet Psychiatry. 2016;3(8):740-750. doi:10.1016/S2215-0366(16)30070-0

  8. National Institute for Health and Care Excellence. Self-harm: Assessment, management and preventing recurrence. NICE guideline [NG225]. 2022. https://www.nice.org.uk/guidance/ng225

  9. Nock MK. Self-injury. Annu Rev Clin Psychol. 2010;6:339-363. doi:10.1146/annurev.clinpsy.121208.131258

  10. Geulayov G, Kapur N, Turnbull P, et al. Epidemiology of suicide and self-harm in the UK. BJPsych Bull. 2016;40(4):186-192. doi:10.1192/pb.bp.115.053181

  11. Carroll R, Metcalfe C, Gunnell D. Hospital presenting self-harm and risk of fatal and non-fatal repetition: Systematic review and meta-analysis. PLoS One. 2014;9(2):e89944. doi:10.1371/journal.pone.0089944

  12. Hawton K, Zahl D, Weatherall R. Suicide following deliberate self-harm: Long-term follow-up of patients who presented to a general hospital. Br J Psychiatry. 2003;182:537-542. doi:10.1192/bjp.182.6.537

  13. McManus S, Gunnell D, Cooper C, et al. Prevalence of non-suicidal self-harm and service contact in England, 2000-14: Repeated cross-sectional surveys of the general population. Lancet Psychiatry. 2019;6(7):573-581. doi:10.1016/S2215-0366(19)30188-9

  14. van Heeringen K, Mann JJ. The neurobiology of suicide. Lancet Psychiatry. 2014;1(1):63-72. doi:10.1016/S2215-0366(14)70220-2

  15. Van Orden KA, Witte TK, Cukrowicz KC, et al. The interpersonal theory of suicide. Psychol Rev. 2010;117(2):575-600. doi:10.1037/a0018697

  16. O'Connor RC, Kirtley OJ. The integrated motivational-volitional model of suicidal behaviour. Philos Trans R Soc Lond B Biol Sci. 2018;373(1754):20170268. doi:10.1098/rstb.2017.0268

  17. Daigle MS. Suicide prevention through means restriction: Assessing the risk of substitution. A critical review and synthesis. Accid Anal Prev. 2005;37(4):625-632. doi:10.1016/j.aap.2005.03.004

  18. Stanley B, Brown GK. Safety Planning Intervention: A brief intervention to mitigate suicide risk. Cogn Behav Pract. 2012;19(2):256-264. doi:10.1016/j.cbpra.2011.01.001

  19. Cipriani A, Hawton K, Stockton S, et al. Lithium in the prevention of suicide in mood disorders: Updated systematic review and meta-analysis. BMJ. 2013;346:f3646. doi:10.1136/bmj.f3646

  20. Linehan MM, Korslund KE, Harned MS, et al. Dialectical behavior therapy for high suicide risk in individuals with borderline personality disorder: A randomized clinical trial and component analysis. JAMA Psychiatry. 2015;72(5):475-482. doi:10.1001/jamapsychiatry.2014.3039

Learning map

Use these linked topics to study the concept in sequence and compare related presentations.

Prerequisites

Start here if you need the foundation before this topic.

Differentials

Competing diagnoses and look-alikes to compare.

Consequences

Complications and downstream problems to keep in mind.

  • Completed Suicide
  • Chronic Self-Harm Wounds