Self-Harm in Adults
Comprehensive evidence-based guide to assessment and management of intentional self-injury in adults, with or without suicidal intent
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Reviewed by MedVellum Editorial Team · MedVellum Medical Education Platform
Credentials: MBBS, MRCP, Board Certified
Self-Harm in Adults
Quick Reference
Critical Alerts
Critical Alert: SAFETY FIRST: Medical stabilization takes priority. Treat overdose, wounds, and poisoning before psychiatric evaluation.
Critical Alert: UNIVERSAL ASSESSMENT: Every patient presenting with self-harm requires formal suicide risk assessment—do not assume non-suicidal intent based on method or appearance.
Critical Alert: DIRECT QUESTIONING: Asking directly about suicidal thoughts does NOT increase risk of suicide. Evidence consistently demonstrates that asking reduces distress and facilitates help-seeking. [1]
Critical Alert: HIGH-RISK OBSERVATION: Patients assessed as high risk require continuous 1:1 observation until comprehensive psychiatric evaluation is completed.
Critical Alert: MEANS RESTRICTION: Actively counsel on restricting access to lethal means—this is one of the most effective suicide prevention interventions. [2]
Key Risk Factors for Suicide Following Self-Harm
| Category | High-Risk Factors |
|---|---|
| Historical | Prior suicide attempt (strongest predictor), psychiatric diagnosis, family history of suicide, childhood trauma/abuse |
| Clinical | Hopelessness, current intoxication, severe insomnia, psychomotor agitation, command hallucinations, anhedonia |
| Situational | Recent significant loss, social isolation, unemployment, relationship breakdown, access to lethal means |
| Demographic | Male sex, older age (> 65), living alone, chronic medical illness |
Emergency Intervention by Risk Level
| Risk Level | Clinical Features | Intervention |
|---|---|---|
| Imminent/High | Active plan with access, recent high-lethality attempt, command hallucinations, severe hopelessness | 1:1 observation, secure environment, psychiatric admission (voluntary or involuntary) |
| Moderate | Suicidal ideation without imminent plan, some protective factors, engaged with assessment | Close observation, psychiatric consultation, possible discharge with comprehensive safety plan |
| Lower | Passive ideation, strong protective factors, engaged in treatment, safe environment | Psychosocial assessment, safety planning, enhanced outpatient follow-up within 48-72 hours |
| Medical Emergency | Overdose, significant wounds, altered consciousness | Immediate medical stabilization; psychiatric assessment when medically stable |
Overview
Self-harm refers to intentional self-inflicted injury regardless of suicidal intent. This encompasses a spectrum from non-suicidal self-injury (NSSI)—where the intent is emotional regulation rather than death—to suicide attempts with clear intent to die. Understanding this distinction is clinically important but should never lead to underestimation of risk, as NSSI independently increases future suicide risk. [3]
Self-harm represents a major public health concern. Globally, approximately 800,000 people die by suicide annually, making it the 10th leading cause of death in high-income countries. [4] Hospital presentations for self-harm have increased substantially, with emergency department visits for intentional self-harm rising by over 40% in the past two decades. [5] The lifetime prevalence of NSSI is approximately 17% among adolescents and 5-6% among adults, while lifetime prevalence of suicide attempts is 2.7% globally. [6]
The assessment and management of self-harm requires a comprehensive biopsychosocial approach. Beyond immediate medical management of injuries or overdose, the clinician must conduct thorough risk assessment, identify underlying psychiatric conditions, address psychosocial stressors, and implement evidence-based interventions including safety planning and connection to appropriate ongoing care. [7]
Definition and Terminology
Core Definitions
Self-harm is defined as intentional self-poisoning or self-injury, irrespective of the apparent purpose of the act. This term is preferred in UK and European literature as it avoids assumptions about intent. [8]
Non-suicidal self-injury (NSSI) refers to the deliberate, self-inflicted destruction of body tissue without suicidal intent and for purposes not socially sanctioned. Common methods include cutting, burning, hitting, and scratching. NSSI is included as a condition for further study in DSM-5. [9]
Suicidal ideation (SI) encompasses thoughts about ending one's own life, ranging from passive wishes ("I wish I were dead") to active planning with intent and method.
Terminology Table
| Term | Definition | Clinical Significance |
|---|---|---|
| Passive suicidal ideation | Wishes to be dead without active consideration of methods ("I wish I didn't wake up") | Lower immediate risk but requires assessment; indicates significant distress |
| Active suicidal ideation | Active thoughts of killing oneself, with or without specific plan | Higher risk; assess for plan, intent, access to means |
| Suicide plan | Specific method, time, and/or place identified | Significantly elevated risk; assess for preparatory behaviors |
| Suicide intent | Subjective expectation or wish that a self-destructive act will result in death | Critical determinant of risk level |
| Suicide attempt | Self-directed, potentially injurious behavior with at least some intent to die | Strongest predictor of future completed suicide |
| Interrupted attempt | Person is interrupted by external circumstances before injury occurs | Assess as high risk; evaluate access to means |
| Aborted attempt | Person begins to take steps but stops themselves | May indicate ambivalence; comprehensive assessment needed |
| Suicide gesture | Behavior with low lethality, ambiguous intent (term now discouraged) | Avoid minimizing language; all self-harm increases risk |
Clinical Pearl: The terms "parasuicide," "deliberate self-harm," and "suicide gesture" are falling out of favor as they may minimize the clinical significance of self-harm. The preferred terminology is "self-harm" with explicit assessment of intent. [8]
Epidemiology
Prevalence and Incidence
Self-harm is substantially more common than completed suicide, representing a significant burden on emergency and mental health services. Data from the Multicentre Study of Self-Harm in England demonstrate an incidence of approximately 400 per 100,000 population per year presenting to hospital. [10]
| Measure | Value | Population | Source |
|---|---|---|---|
| Hospital presentations for self-harm | 400 per 100,000/year | UK adults | [10] |
| Lifetime prevalence of NSSI | 5.5% | General adult population | [6] |
| Lifetime prevalence of suicide attempt | 2.7% | Global | [6] |
| Repetition rate within 1 year | 15-25% | Following self-harm presentation | [11] |
| Suicide within 1 year of self-harm | 1-2% | Following hospital presentation | [12] |
| Lifetime suicide following self-harm | 3-7% | Long-term follow-up | [12] |
Demographics
Sex differences: Females present to hospital for self-harm at approximately 1.5 times the rate of males. However, males account for approximately 75% of completed suicides. This "gender paradox" reflects differences in method choice, with males more commonly using high-lethality methods. [4]
Age distribution: Peak rates of self-harm presentation occur in females aged 15-24 years and males aged 25-34 years. Suicide rates increase with age, particularly in males, with the highest rates in those aged over 75 years. [4]
Socioeconomic factors: Self-harm rates are strongly associated with social deprivation, unemployment, and lower educational attainment. Rates are approximately three times higher in the most deprived areas compared to the least deprived. [10]
Trends
Hospital presentations for self-harm have increased substantially over the past two decades. Data from the UK Multicentre Study demonstrate a 73% increase in self-harm presentations among young females aged 16-24 years between 2000 and 2014. [13] More recent data suggest continued increases, particularly during and following the COVID-19 pandemic. [5]
Aetiology and Risk Factors
Biopsychosocial Framework
Self-harm results from complex interactions between biological vulnerabilities, psychological factors, and social/environmental stressors.
Biological Factors
| Factor | Evidence | Mechanism |
|---|---|---|
| Serotonergic dysfunction | Reduced 5-HIAA in CSF, altered serotonin transporter binding | Impulsivity, aggression, mood dysregulation |
| HPA axis dysregulation | Blunted cortisol response, elevated baseline cortisol | Stress response abnormalities |
| Genetic factors | Family studies demonstrate heritability of 30-50% | Likely polygenic with gene-environment interactions |
| Neuroinflammation | Elevated inflammatory markers (IL-6, CRP) | Potential link between physical and mental health |
Exam Detail: Neurobiological Correlates
Neuroimaging studies have identified structural and functional abnormalities in individuals with suicidal behavior:
- Prefrontal cortex: Reduced gray matter volume and activity, associated with impaired decision-making and impulse control
- Amygdala: Heightened reactivity to negative emotional stimuli
- Anterior cingulate cortex: Abnormalities in error monitoring and conflict resolution
- Orbitofrontal cortex: Altered reward processing and behavioral inhibition
The serotonergic system is most strongly implicated, with reduced serotonin transporter binding and blunted serotonin synthesis capacity. This may underlie the impulsivity and aggression associated with suicidal behavior. [14]
Psychological Factors
| Factor | Description | Clinical Relevance |
|---|---|---|
| Hopelessness | Negative expectations about the future | Stronger predictor than depression alone; assess directly |
| Psychological pain (psychache) | Unbearable psychological suffering | Core driver; reducing pain is therapeutic target |
| Cognitive rigidity | Inability to generate alternative solutions | "Tunnel vision"; cognitive therapy targets this |
| Perfectionism | Self-critical perfectionism, perceived failure | Common in high-achieving individuals |
| Poor distress tolerance | Inability to tolerate negative emotional states | Target of DBT skills training |
| Emotional dysregulation | Difficulty modulating emotional responses | Core feature of NSSI function |
Social and Environmental Factors
| Factor | Impact | Evidence Level |
|---|---|---|
| Childhood trauma/abuse | 2-5x increased risk | Strong |
| Recent significant loss | Relationship, employment, bereavement | Strong |
| Social isolation | Lack of connectedness, living alone | Strong |
| Financial difficulties | Debt, unemployment, housing insecurity | Moderate |
| Access to lethal means | Particularly firearms, medications | Strong |
| Media exposure | Contagion effects, especially in young people | Moderate |
| Social media | Cyberbullying, exposure to self-harm content | Emerging |
Psychological Models
Interpersonal Theory of Suicide (Joiner)
This influential model proposes that suicide capability requires the simultaneous presence of: [15]
- Thwarted belongingness: Unmet need for social connectedness ("I am alone")
- Perceived burdensomeness: Belief that one is a burden on others ("I am a burden")
- Acquired capability: Reduced fear of death and elevated pain tolerance, often acquired through repeated exposure to painful or provocative experiences (including NSSI)
Clinical Pearl: NSSI may contribute to "acquired capability" for suicide by habituating the individual to self-inflicted pain and injury. This is one mechanism by which NSSI increases future suicide risk, even in the absence of initial suicidal intent.
Integrated Motivational-Volitional Model (O'Connor)
This three-phase model describes the pathway to suicidal behavior: [16]
- Pre-motivational phase: Background factors and triggering events
- Motivational phase: Development of suicidal ideation through defeat/entrapment perceptions
- Volitional phase: Transition from ideation to action, moderated by capability factors
This model emphasizes that most people with suicidal ideation do not attempt suicide—understanding factors that facilitate transition to action is crucial.
Psychiatric Comorbidity
The vast majority of individuals who die by suicide have a diagnosable psychiatric disorder. Key associations include:
| Disorder | Relative Risk for Suicide | Key Features |
|---|---|---|
| Major Depressive Disorder | 20x | Hopelessness, anhedonia, sleep disturbance |
| Bipolar Disorder | 20-30x | Mixed states, depressive episodes, impulsivity |
| Schizophrenia | 8-10x | Command hallucinations, early illness, post-discharge |
| Borderline Personality Disorder | 45x | Chronic suicidality, NSSI, emotional dysregulation |
| Alcohol Use Disorder | 5-10x | Intoxication increases impulsivity; withdrawal states |
| Substance Use Disorder | 7x | Polysubstance use, opioid use disorder |
| Anorexia Nervosa | 30x | Highest mortality of any psychiatric disorder |
| PTSD | 4-6x | Particularly with comorbid depression |
Methods of Self-Harm
Overview of Methods
The method of self-harm provides important clinical information but should not be used to infer suicidal intent or predict future risk. Method availability strongly influences choice. [17]
| Method | Proportion of Presentations | Lethality | Key Considerations |
|---|---|---|---|
| Self-poisoning | 70-80% | Variable | Most common ED presentation; acetaminophen, NSAIDs, antidepressants most frequent |
| Cutting | 20-25% | Usually low | Most common NSSI method; forearms, thighs typical locations |
| Hanging/strangulation | 2-5% | High | High lethality; associated with completed suicide |
| Jumping | less than 1% | High | Access to height is key modifiable factor |
| Firearm | less than 1% (UK); 50% (US suicides) | Very high | Most lethal method; access is critical factor |
| Burning | 1-2% | Variable | May indicate severe psychopathology |
| Head-banging/hitting | 5-10% | Usually low | Common in developmental disorders, acute distress |
Self-Poisoning (Overdose)
Self-poisoning accounts for the majority of hospital presentations for self-harm. Common substances include:
Medications:
- Acetaminophen (paracetamol): Most common; serious hepatotoxicity risk
- Non-steroidal anti-inflammatory drugs
- Antidepressants (particularly TCAs, SSRIs in combination)
- Benzodiazepines
- Opioids (increasingly common)
- Antipsychotics
Other substances:
- Alcohol (often in combination)
- Illicit drugs
- Household products
Critical Alert: STAGGERED OVERDOSE: Patients may take multiple doses over several hours or days. This pattern is associated with worse outcomes in acetaminophen poisoning and requires specific management protocols.
Non-Suicidal Self-Injury (NSSI)
NSSI serves specific psychological functions, most commonly: [9]
- Affect regulation: Rapid relief from intense negative emotions (most common)
- Self-punishment: Response to self-directed anger or guilt
- Anti-dissociation: Generation of feeling when experiencing numbing/depersonalization
- Interpersonal influence: Communication of distress (less common than perceived)
- Sensation-seeking: In context of emotional numbness
Common methods and locations:
- Cutting: Forearms, thighs, abdomen
- Burning: Cigarettes, heated objects
- Scratching/picking: Arms, hands
- Hitting/banging: Head, limbs against hard surfaces
Clinical Pearl: Understanding the function of NSSI guides treatment. If the primary function is affect regulation, treatment focuses on developing alternative emotion regulation strategies (central to DBT). If the function is anti-dissociative, grounding techniques are prioritized.
Clinical Presentation
History Taking
A comprehensive psychiatric history is essential. Key domains include:
Presenting Episode
About the self-harm act:
- What method(s) were used?
- What was the timing and sequence of events?
- Where did it occur and who was present?
- Was there planning or was it impulsive?
- Were precautions taken against discovery?
- Did they seek help afterward or expect to be discovered?
- What substances were involved (type, quantity, timing)?
About intent:
- "Did you want to die?"
- "Did you expect to die?"
- "Are you disappointed to have survived?"
- "What did you hope would happen?"
- "What, if anything, stopped you from doing more?"
About current mental state:
- Ongoing suicidal ideation?
- Current plan or intent?
- Reasons for living vs. reasons for dying?
- Hopelessness about the future?
Current Suicidal Ideation
Use structured questioning to assess:
| Domain | Key Questions |
|---|---|
| Frequency | "How often do you have thoughts about ending your life?" |
| Intensity | "How strong are these thoughts?" |
| Duration | "How long do these thoughts last?" |
| Controllability | "Can you dismiss these thoughts or do they take over?" |
| Plan | "Have you thought about how you would do it?" |
| Access to means | "Do you have access to [method]? Are there firearms/medications at home?" |
| Preparatory behaviors | "Have you done anything to prepare—giving things away, writing notes?" |
| Deterrents | "What stops you from acting on these thoughts?" |
Psychiatric History
- Previous self-harm or suicide attempts (strongest predictor)
- Psychiatric diagnoses and hospitalizations
- Current treatment and medication
- Engagement with mental health services
- History of trauma or abuse
Medical History
- Chronic medical conditions (pain, disability, terminal illness)
- Recent diagnoses or health deterioration
- Medications (assess lethality of available medications)
Substance Use
- Alcohol: Current intoxication, dependence, recent changes
- Drugs: Type, frequency, recent use
- Prescription medication misuse
Social History
- Living situation and social supports
- Employment/financial status
- Relationships and recent losses
- Access to lethal means (firearms, medications)
- Children or dependents
Mental State Examination
Systematic mental state examination is essential:
| Domain | Key Observations |
|---|---|
| Appearance | Evidence of self-harm wounds (old/new), self-neglect, intoxication |
| Behavior | Agitation, retardation, eye contact, engagement |
| Speech | Rate, volume, tone (flat, monotonous may indicate depression) |
| Mood | Subjective: "How would you describe your mood?" |
| Affect | Objective: Range, reactivity, congruence |
| Thought content | Suicidal ideation, hopelessness, worthlessness, guilt |
| Perceptions | Hallucinations, particularly command auditory hallucinations |
| Cognition | Orientation, concentration (may indicate intoxication, delirium) |
| Insight | Understanding of illness, need for treatment |
| Judgment | Ability to make safe decisions |
Critical Alert: COMMAND HALLUCINATIONS: Always specifically ask about voices commanding self-harm or suicide. Patients may not volunteer this information. Command hallucinations with perceived malevolent identity and history of acting on commands confer highest risk.
Physical Examination
General assessment:
- Vital signs (tachycardia, hypotension, fever may indicate toxicity)
- Level of consciousness (GCS)
- Pupil size and reactivity
- Signs of intoxication
- Evidence of trauma
Wound assessment for cutting/self-injury:
| Feature | Assessment | Clinical Significance |
|---|---|---|
| Location | Forearms, thighs, abdomen common for NSSI | Hidden locations may indicate secrecy |
| Depth | Superficial, dermal, subcutaneous, tendon/vessel involvement | Deeper wounds require surgical assessment |
| Number | Single vs. multiple; old vs. new | Chronicity pattern |
| Pattern | Parallel lines, words, random | May indicate specific pathology |
| Healing stage | Fresh, healing, scarred | Evidence of chronicity |
Signs suggestive of significant overdose:
- Altered mental status
- Respiratory depression
- Tachycardia or bradycardia
- Hypotension or hypertension
- Seizures
- Hepatic tenderness (acetaminophen)
- Nystagmus, ataxia (anticonvulsants)
Red Flags
Features Indicating High Suicide Risk
Critical Alert: The following features indicate HIGH or IMMINENT suicide risk and typically warrant psychiatric admission:
| Red Flag | Why It Matters |
|---|---|
| Active plan with access to lethal means | Imminent risk; capability is present |
| Recent high-lethality attempt | Method lethality correlates with future risk |
| Disappointment at survival | Intent persists; ambivalence absent |
| Command auditory hallucinations to harm self | Compelling force to act; reduced volition |
| Severe hopelessness with no reasons for living | Hopelessness is strongest cognitive predictor |
| Current intoxication with suicidal ideation | Intoxication disinhibits and increases impulsivity |
| Recent discharge from psychiatric inpatient unit | Highest risk period is first 2 weeks post-discharge |
| Social isolation with no supports | No external protective factors |
| Preparatory behaviors | Giving possessions away, writing notes, putting affairs in order |
| Recent significant loss | Relationship breakdown, bereavement, job loss |
| History of multiple prior attempts | Each attempt increases future risk |
Protective Factors
Protective factors may mitigate risk but should never lead to dismissal of concerning features:
| Protective Factor | Consideration |
|---|---|
| Strong social support | Family, friends actively involved |
| Children or dependents | Responsibility, connection |
| Engaged in treatment | Therapeutic alliance, help-seeking |
| Future-oriented plans | Goals, upcoming events |
| Religious/moral objections | May prevent action despite ideation |
| No access to lethal means | Reduced capability |
| Ambivalence about death | Some wish to live |
| Fear of death or pain | Barrier to action |
Differential Diagnosis
Primary Considerations
| Condition | Features | Key Differentiators |
|---|---|---|
| Major Depression with suicidal ideation | Low mood, anhedonia, neurovegetative symptoms | Pervasive hopelessness, suicidal ideation typical |
| Borderline Personality Disorder | Chronic NSSI, emotional dysregulation, interpersonal instability | Recurrent pattern, impulsive self-harm, affect regulation function |
| Psychotic disorder with command hallucinations | Acting on voices, bizarre ideation | Assess for hallucinations; may lack apparent "reason" |
| Bipolar disorder (mixed or depressive episode) | Agitation, mood instability, impulsivity | Mixed states particularly high risk |
| Substance use disorder | Intoxication, withdrawal, impulsivity | Reassess when sober; address comorbidity |
| Adjustment disorder | Clear precipitant, time-limited distress | Identifiable stressor, preserved functioning otherwise |
| PTSD | Trauma-related distress, flashbacks, avoidance | NSSI may be trauma-related coping mechanism |
Other Considerations
| Condition | Features |
|---|---|
| Delirium | Confusion, fluctuating consciousness; self-harm may be accidental or secondary to disorientation |
| Dementia | Cognitive impairment; self-harm may occur during behavioral disturbance |
| Factitious disorder | Self-inflicted injuries to assume sick role; denial of self-causation |
| Accidental overdose | Denies suicidal intent; assess carefully for minimization |
| Malingering | External incentive (avoid incarceration, obtain housing); rare |
Clinical Pearl: Patients with personality disorders who present repeatedly with self-harm are sometimes dismissed as "not really suicidal." This is dangerous—the suicide rate in borderline personality disorder is 8-10%, and repeated NSSI is a strong risk factor for eventual completed suicide.
Investigations
Medical Assessment
All patients presenting with self-harm require medical evaluation to exclude toxicity or injury requiring treatment.
Mandatory for All Overdoses
| Investigation | Indication | Key Values |
|---|---|---|
| Blood glucose | Altered consciousness | Rule out hypoglycemia |
| Acetaminophen level | All overdoses (even if denied) | Plot on Rumack-Matthew nomogram at ≥4 hours |
| Salicylate level | All overdoses | Toxic > 300 mg/L; severe > 700 mg/L |
| Urea, creatinine, electrolytes | Baseline renal function; overdose assessment | Electrolyte disturbance, renal toxicity |
| Liver function tests | Hepatotoxic ingestion (acetaminophen, others) | ALT/AST elevation indicates hepatic injury |
| ECG | Cardiotoxic drugs (TCAs, antipsychotics, antiarrhythmics) | QRS prolongation, QTc prolongation, arrhythmia |
| Blood alcohol level | Suspected intoxication | May affect capacity assessment |
Additional Investigations Based on Presentation
| Investigation | Indication |
|---|---|
| Urine drug screen | Suspected substance use; clinical features unexplained |
| Arterial blood gas | Significant overdose, altered consciousness, respiratory concerns |
| Coagulation studies | Anticoagulant ingestion, hepatic damage |
| Creatine kinase | Prolonged immobility, muscle damage |
| Venous lactate | Metformin ingestion, tissue hypoxia |
| CT head | Head injury, unexplained altered consciousness |
Psychiatric Assessment Tools
Columbia Suicide Severity Rating Scale (C-SSRS)
The C-SSRS is a validated, structured interview tool for assessing suicide risk. It assesses: [1]
- Severity of ideation (5 levels from passive to active with intent and plan)
- Intensity of ideation (frequency, duration, controllability)
- Suicidal behavior (actual attempts, interrupted/aborted attempts, preparatory behaviors)
Clinical Pearl: The C-SSRS provides standardized language and structure for suicide risk assessment. It is freely available and widely recommended in emergency settings.
Other Validated Tools
| Tool | Use | Limitations |
|---|---|---|
| Beck Hopelessness Scale | Quantify hopelessness | Self-report; may underreport |
| Patient Health Questionnaire-9 (PHQ-9) | Depression severity; item 9 screens for self-harm | Brief screen only |
| SAD PERSONS scale | Mnemonic risk assessment | Poor predictive validity; not recommended alone |
| Manchester Self-Harm Rule | Predict repetition risk | Clinical decision support, not replacement |
Critical Alert: LIMITATIONS OF TOOLS: No risk assessment tool can accurately predict suicide at an individual level. Scales should inform—not replace—comprehensive clinical assessment. Over-reliance on tools may lead to false reassurance or false alarm.
Psychosocial Assessment
NICE Guidance
NICE Clinical Guideline 16 recommends that all individuals presenting with self-harm receive a comprehensive psychosocial assessment, ideally within 48 hours and certainly before discharge. [8]
This assessment should include:
- Circumstances of the self-harm
- Current suicidal intent and mental state
- Hopelessness
- Psychiatric history and diagnosis
- Social circumstances and supports
- Personal resources and coping strategies
- Risk of further self-harm or suicide
- Need for ongoing treatment and appropriate setting
Structured Approach
| Domain | Key Elements to Assess |
|---|---|
| Current episode | Method, planning, intent, lethality, chance of discovery, attitude to survival |
| Mental state | Depression, psychosis, anxiety, intoxication, hopelessness |
| Psychiatric history | Diagnoses, previous self-harm, treatment history |
| Personal history | Trauma, abuse, losses, personality difficulties |
| Current circumstances | Relationships, living situation, employment, stressors |
| Coping resources | Previous strategies, supports, protective factors |
| Risk formulation | Integration of risk and protective factors; clinical judgment |
Risk Assessment and Formulation
Principles of Risk Assessment
Risk assessment is a clinical process, not a bureaucratic checkbox exercise. The goal is to understand the individual's current state and develop a management plan that addresses modifiable risk factors.
Key principles:
- Risk is dynamic: Risk changes over time and with circumstances
- Risk is contextual: Environmental factors (means access, supports) are crucial
- Prediction is limited: Focus on reducing modifiable factors, not predicting the unpredictable
- Documentation is essential: Record reasoning, not just risk level label
Risk Stratification
| Level | Features | Management Considerations |
|---|---|---|
| High/Imminent | Active intent, plan, access to means; recent high-lethality attempt; severe hopelessness; psychosis with command hallucinations; no protective factors | Psychiatric admission (voluntary or involuntary); 1:1 observation; secure environment |
| Moderate | Suicidal ideation without clear intent/plan; some protective factors; underlying treatable condition; some engagement | Psychiatric consultation; consider admission vs. comprehensive community plan; close follow-up |
| Lower | Passive ideation only; strong protective factors; no plan/intent; engaged in treatment; safe environment | Safety planning; enhanced outpatient follow-up within 72 hours; means counseling |
Clinical Pearl: Risk stratification is a communication tool and guide to intensity of intervention—not a prediction of outcome. A patient rated "low risk" may still complete suicide; a "high risk" patient may not. Document the reasoning behind your formulation.
Risk Formulation
A risk formulation synthesizes the assessment into a coherent narrative that explains the individual's current state and guides management.
Components:
- Predisposing factors: What made this person vulnerable? (e.g., childhood trauma, family history, personality traits)
- Precipitating factors: What triggered this episode? (e.g., relationship breakdown, job loss)
- Perpetuating factors: What is keeping them at risk? (e.g., ongoing depression, hopelessness, social isolation)
- Protective factors: What may prevent further self-harm? (e.g., children, engaged in treatment, future plans)
- Risk level and rationale: Synthesis of above; explicit statement of reasoning
- Management plan: What will be done to address modifiable factors
Management
Principles
- Medical stabilization first: Treat overdose, wounds, poisoning before psychiatric assessment
- Compassionate, non-judgmental care: Stigmatizing attitudes worsen outcomes and reduce help-seeking
- Comprehensive assessment: Every patient deserves thorough evaluation
- Least restrictive intervention: Balance safety with autonomy
- Address underlying causes: Treat psychiatric illness, address psychosocial stressors
- Means restriction: Reduce access to lethal methods
- Continuity of care: Seamless transition from emergency to ongoing care
Acute Medical Management
Self-Poisoning/Overdose
Refer to specific toxicology protocols. Key principles:
| Intervention | Indication | Notes |
|---|---|---|
| Activated charcoal | Within 1 hour of ingestion (some drugs up to 2 hours) | Not for hydrocarbons, alcohols, metals, corrosives |
| N-acetylcysteine | Acetaminophen overdose per nomogram | Start immediately if staggered overdose or late presentation with elevated ALT |
| Gastric lavage | Rarely indicated; large ingestion less than 1 hour | Only in protected airway |
| Whole bowel irrigation | Sustained-release formulations, body packing | Polyethylene glycol solution |
| Specific antidotes | Naloxone (opioids), flumazenil (benzodiazepines with caution), sodium bicarbonate (TCA) | Follow toxicology guidance |
Wound Management
| Wound Type | Management |
|---|---|
| Superficial cuts | Clean, assess tetanus status, wound closure if needed, safety planning |
| Deep lacerations | Assess tendon/neurovascular injury, surgical referral if needed |
| Ligature marks | Assess airway, imaging if concern for vascular/laryngeal injury |
| Burns | Standard burn management; assess surface area and depth |
Emergency Department Safety
| Intervention | Purpose |
|---|---|
| 1:1 observation | Continuous monitoring for high-risk patients |
| Environmental safety | Remove sharps, cords, medications from patient access |
| Search of belongings | Per protocol; explain rationale |
| Secure room | Ligature-resistant if available |
| Elopement precautions | Monitor exits; locked unit if appropriate |
Psychiatric Management
For High-Risk Patients
- Inpatient psychiatric admission: Voluntary or involuntary under mental health legislation
- Continuous 1:1 observation until admission
- Psychiatry consultation for admission planning
- Medication review: Address undertreated psychiatric illness
For Moderate-Risk Patients
Careful clinical judgment required. May consider discharge with:
- Comprehensive safety plan
- Strong social support engaged
- Means restriction implemented
- Outpatient follow-up within 24-72 hours
- Clear crisis pathway identified
- Underlying condition addressed (medication started/adjusted)
For Lower-Risk Patients
- Safety planning intervention
- Outpatient mental health referral
- Means restriction counseling
- Crisis resources provided
- Follow-up within 72 hours
Safety Planning Intervention
The Safety Planning Intervention (SPI) is an evidence-based, brief intervention that reduces suicidal behavior. [18] It differs from "no-suicide contracts," which lack evidence of effectiveness.
Stanley-Brown Safety Planning Intervention Components:
| Step | Content | Example |
|---|---|---|
| 1. Warning signs | Recognition of personal crisis triggers | "When I start feeling worthless and can't stop crying" |
| 2. Internal coping strategies | What can I do alone to feel better? | "Take a walk, listen to music, breathing exercises" |
| 3. Social contacts for distraction | People/places to distract from crisis | "Go to friend's house, call sister to chat about other things" |
| 4. People to ask for help | Specific individuals to contact in crisis | "Call my partner, my best friend Sarah" |
| 5. Professionals to contact | Mental health professionals, crisis services | "My therapist [number], Crisis team [number], 988 (US)/Samaritans 116 123 (UK)" |
| 6. Making the environment safe | Means restriction | "Partner will lock away medications, remove firearms from home" |
Clinical Pearl: Safety planning is collaborative—developed WITH the patient, not given TO them. The process of creating the plan is therapeutic. Provide a written copy and photograph for their phone.
Means Restriction
Means restriction is one of the most effective suicide prevention interventions. [2] Counsel all patients and their families on:
Medications:
- Lock up all medications, including over-the-counter
- Dispose of unneeded medications safely
- Prescribe limited quantities (e.g., 1 week supply)
- Consider blister packs rather than bottles
Firearms:
- Most lethal method; firearm access dramatically increases suicide risk
- Counsel on temporary removal or secure storage
- Unloaded, locked, ammunition stored separately
- Ideally removed from the home entirely during crisis
Other means:
- Secure ligature points
- Limit access to heights
- Remove/secure sharp objects
Clinical Pearl: Means restriction works because many suicidal crises are time-limited. Introducing a barrier buys time for the crisis to pass. Substitution to other methods is less common than expected.
Pharmacotherapy
There is no medication specifically approved for acute suicidality, but treatment of underlying psychiatric conditions is essential.
| Medication Class | Role | Evidence |
|---|---|---|
| Antidepressants | Treat underlying depression | Reduce suicide risk with treatment, despite black box warning about initial increased risk in young people |
| Lithium | Mood stabilization in bipolar; specific anti-suicidal effect | Strong evidence for suicide prevention in bipolar disorder [19] |
| Clozapine | Schizophrenia with suicidality | FDA-approved for reducing suicide in schizophrenia |
| Ketamine/esketamine | Rapid reduction in suicidal ideation | Emerging evidence; esketamine approved for treatment-resistant depression with suicidality |
Exam Detail: Lithium's Anti-Suicidal Effect
Lithium has a specific anti-suicidal effect independent of its mood-stabilizing properties. Meta-analyses demonstrate approximately 80% reduction in suicide risk in patients with mood disorders. The mechanism may relate to serotonergic effects and reduction in impulsivity and aggression. [19]
Psychotherapy
Dialectical Behavior Therapy (DBT)
DBT is the most extensively studied treatment for individuals with borderline personality disorder and chronic self-harm. [20] It is considered the gold standard for NSSI.
Components:
- Individual therapy
- Skills training group (core skills: mindfulness, distress tolerance, emotion regulation, interpersonal effectiveness)
- Phone coaching for crisis skills application
- Therapist consultation team
Evidence: Multiple RCTs demonstrate reduced self-harm, reduced suicide attempts, and reduced hospitalization.
Other Evidence-Based Therapies
| Therapy | Indication | Evidence |
|---|---|---|
| Cognitive Behavioral Therapy (CBT) | Depression, anxiety, suicidal ideation | Strong evidence for depression; emerging for suicide-specific CBT |
| Mentalization-Based Therapy (MBT) | Borderline personality disorder | Reduced self-harm and suicide attempts |
| Collaborative Assessment and Management of Suicidality (CAMS) | Suicide-focused treatment framework | Emerging evidence for reduced ideation |
| Brief intervention and contact | Post-ED care | WHO BIC reduces suicide; caring contacts effective |
Disposition
Criteria for Psychiatric Admission
Critical Alert: The following features typically indicate need for inpatient psychiatric care:
| Indication | Rationale |
|---|---|
| Active suicidal ideation with plan and intent | Imminent risk requires secure environment |
| Recent high-lethality suicide attempt | Demonstrated capability and intent |
| Psychosis with command hallucinations to self-harm | Reduced volition; compelling force to act |
| Severe hopelessness with no reasons for living | Core cognitive risk factor unaddressed |
| Inability to engage in safety planning | Cannot participate in outpatient risk mitigation |
| Inadequate social support | No external protective factors |
| Acute psychiatric illness requiring stabilization | E.g., severe depression, mania, psychosis |
| Previous self-harm shortly after ED/hospital discharge | Pattern of post-discharge deterioration |
Involuntary Admission
When a patient refuses voluntary admission and meets criteria for danger to self, involuntary admission under mental health legislation may be necessary.
UK (Mental Health Act 1983):
- Section 2: Assessment (up to 28 days)
- Section 3: Treatment (up to 6 months)
- Section 5(2): Doctor's holding power (up to 72 hours)
Documentation requirements:
- Evidence of mental disorder
- Nature and degree warranting detention
- Necessity for health, safety, or protection of others
- Least restrictive option considered
Criteria for Discharge
Patients may be considered for discharge with community follow-up if:
| Criterion | Description |
|---|---|
| No current suicidal intent | Ideation may be present but no intent/plan |
| Adequate protective factors | Social support, engaged with treatment, reasons for living |
| Means restriction in place | Lethal means removed/secured |
| Safety plan completed | Collaborative plan with patient and supports |
| Follow-up arranged | Mental health appointment within 48-72 hours |
| Crisis pathway clear | Patient knows how to access help |
| Not intoxicated | Can participate meaningfully in assessment and planning |
| Underlying condition addressed | Medication adjusted, crisis precipitant addressed |
Follow-Up
| Population | Recommended Follow-Up |
|---|---|
| Post-self-harm ED presentation | Within 48-72 hours |
| Post-psychiatric admission | Within 7 days of discharge |
| High-risk patients in community | Same-week contact |
| Ongoing suicidal ideation | Weekly or more frequent until stable |
Clinical Pearl: The first 1-2 weeks after discharge from psychiatric inpatient care is the highest-risk period for suicide. Intensive follow-up during this transition is critical.
Special Populations
Older Adults
- Higher lethality: More lethal methods, less likely to survive attempts
- Less warning: May give fewer verbal warnings of intent
- Physical illness: Chronic disease, disability, pain are risk factors
- Social isolation: Widowhood, decreased mobility, loneliness
- Depression often unrecognized: May present as somatic complaints
Assessment considerations: Screen for depression, assess functional status, social network, and physical health comorbidities.
LGBTQ+ Individuals
- Elevated risk: 2-3x higher rates of suicidal ideation and attempts
- Contributing factors: Minority stress, discrimination, family rejection, identity-related distress
- Protective factors: Affirming environments, community connection, family acceptance
Assessment considerations: Create affirming environment, ask about gender identity and pronouns, assess for discrimination-related distress.
People with Intellectual Disabilities
- Underrecognized: Self-harm may be attributed to challenging behavior
- Communication difficulties: May have difficulty expressing distress
- Increased vulnerability: Trauma, abuse, loss more common
Assessment considerations: Adapted communication, involve caregivers, assess for pain/physical causes of behavioral change.
Perinatal Period
- Perinatal mental illness: Significant risk factor for self-harm and suicide
- Suicide is leading cause of maternal death: In high-income countries
- Specific considerations: Baby's welfare, bonding, support needs
Assessment considerations: Perinatal mental health team involvement, mother-baby unit consideration, safeguarding.
Substance Use Disorders
- High comorbidity: Greatly elevated suicide risk
- Intoxication increases impulsivity: Reassess when sober
- Chronic use increases risk: Even when not acutely intoxicated
Assessment considerations: Assess for withdrawal, integrated mental health and substance treatment, address SUD in care plan.
Chronic Self-Harm
- Pattern of repeated NSSI: Often in context of borderline personality disorder
- Not "just attention seeking": NSSI confers significant suicide risk
- Compassion fatigue in providers: Maintain non-judgmental stance
Assessment considerations: Each presentation deserves thorough assessment; DBT referral; avoid dismissive attitudes.
Patient and Family Education
For the Patient
Key messages to communicate:
- "What you're going through is serious, and help is available."
- "These thoughts and feelings can change with treatment and support."
- "We've made a safety plan together—please use it when you're struggling."
- "It's important to remove access to things that could hurt you."
- "Please come back to the ED or call the crisis line if things get worse."
For Family/Support Persons
Key messages:
- "Your loved one is going through a very difficult time."
- "You can help by removing access to medications, firearms, and other means."
- "Watch for warning signs: increased talk of death, giving things away, social withdrawal."
- "Encourage use of the safety plan and follow-up appointments."
- "It's OK to ask directly about suicidal thoughts—it doesn't make things worse."
- "If you're concerned, bring them back to the ED or call the crisis line."
Crisis Resources
International:
- International Association for Suicide Prevention: https://www.iasp.info/resources/Crisis_Centres/
United Kingdom:
- Samaritans: 116 123 (24/7, free)
- Crisis Text Line: Text SHOUT to 85258
- Papyrus (under 35s): 0800 068 4141
United States:
- 988 Suicide and Crisis Lifeline: Call or text 988
- Crisis Text Line: Text HOME to 741741
- Veterans Crisis Line: 988, press 1
Australia:
- Lifeline: 13 11 14
- Beyond Blue: 1300 22 4636
- Suicide Call Back Service: 1300 659 467
Prognosis
Risk of Repetition
Following a self-harm presentation:
| Timeframe | Repetition Rate | Suicide Rate |
|---|---|---|
| 1 year | 15-25% | 1-2% |
| 5 years | 30-40% | 3-5% |
| Lifetime | 50%+ | 5-10% |
Factors Associated with Worse Outcome
| Factor | Impact |
|---|---|
| Previous suicide attempt | Strongest predictor of future completed suicide |
| Psychiatric illness | Particularly if untreated |
| Substance use disorder | Independent additive risk |
| Social isolation | Lack of protective factors |
| Continued access to means | Capability maintained |
| Non-engagement with follow-up | Missed opportunity for intervention |
Factors Associated with Better Outcome
| Factor | Impact |
|---|---|
| Treatment engagement | Psychotherapy, medication compliance |
| Strong social support | Family, friends involved |
| Means restriction | Reduced capability |
| Resolution of precipitants | Relationship, employment stabilized |
| Development of coping strategies | Skills to manage future crises |
Quality Metrics and Documentation
Documentation Requirements
All self-harm assessments should document:
| Element | Content |
|---|---|
| Presenting complaint | Description of self-harm episode |
| Mental state examination | Systematic MSE |
| Risk assessment | Factors assessed, risk level, reasoning |
| Protective factors | What mitigates risk |
| Capacity assessment | If relevant to decision-making |
| Risk formulation | Synthesis narrative |
| Management plan | Specific interventions, follow-up |
| Safety plan | If completed, attach/summarize |
| Means restriction | Counseling provided, actions taken |
| Crisis resources | Provided to patient |
| Collateral information | Sources contacted |
| Disposition and reasoning | Why this level of care |
Quality Indicators
| Metric | Target | Rationale |
|---|---|---|
| Psychosocial assessment documented | 100% | Standard of care; NICE mandate |
| Safety plan provided at discharge | 100% | Evidence-based intervention |
| Means restriction counseling | 100% | Effective prevention |
| Follow-up appointment arranged | 100% | Transition of care |
| Mental health follow-up within 7 days | > 95% | High-risk transition period |
| Risk assessment documented | 100% | Clinical and medicolegal requirement |
Key Clinical Pearls
Assessment
Clinical Pearl: Ask directly about suicide. Research consistently shows that asking about suicidal thoughts does not increase risk—it often provides relief and facilitates help-seeking. Avoiding the question due to discomfort is a missed opportunity.
Clinical Pearl: Prior suicide attempt is the strongest predictor of future completed suicide. Always ask about previous self-harm in detail: method, lethality, intent, what interrupted the attempt.
Clinical Pearl: Hopelessness is more predictive than depression severity. A patient may score "moderately" depressed but have profound hopelessness—this warrants heightened concern.
Clinical Pearl: Reassess when sober. Intoxication impairs judgment and increases impulsivity. A patient who appears high-risk while intoxicated may be lower risk when sober—but requires reassessment, not assumption.
Clinical Pearl: NSSI is not "just attention seeking". Non-suicidal self-injury confers significant risk for future suicide. Every episode deserves thorough assessment and compassionate care.
Management
Clinical Pearl: Safety planning is evidence-based; "no-suicide contracts" are not. Safety planning is collaborative, specific, and addresses capability. Contracts are passive and lack evidence of effectiveness.
Clinical Pearl: Means restriction saves lives. Counseling on means restriction (especially firearms) is one of the most effective interventions. Most crises are time-limited—barriers buy time.
Clinical Pearl: Follow-up within 72 hours is critical. The period after ED discharge or inpatient care is high-risk. Ensure clear follow-up and that the patient knows how to access help.
Clinical Pearl: Document your reasoning, not just the risk level. A risk level label without explanation is clinically and legally insufficient. Explain why you assessed risk as you did and what your plan addresses.
Disposition
Clinical Pearl: High risk = psychiatric evaluation and usually admission. When risk is high, err on the side of caution. A missed high-risk patient has catastrophic consequences.
Clinical Pearl: Involve family and supports. Engage trusted others in safety planning, means restriction, and monitoring. They are a crucial part of the safety net.
Exam-Focused Content
Common Viva Questions
- "A 25-year-old woman presents after cutting her forearms. How would you assess her?"
- "What are the key risk factors for suicide following self-harm?"
- "How do you distinguish between NSSI and a suicide attempt?"
- "What is the evidence for safety planning interventions?"
- "When would you consider involuntary admission for a patient with self-harm?"
- "What is the role of means restriction in suicide prevention?"
- "How do you manage a patient with chronic self-harm and borderline personality disorder?"
- "What are the principles of psychosocial assessment after self-harm?"
Model Viva Answer
Q: "A 35-year-old man presents to the emergency department after a paracetamol overdose. Describe your approach to assessment and management."
A: "I would approach this systematically, addressing both medical and psychiatric aspects.
Medical management first: I would assess the quantity and timing of ingestion, as this determines management. I would take blood at 4 hours post-ingestion for paracetamol level and plot this on the nomogram. If the level is above the treatment line, or if there's any doubt about timing (staggered overdose), I would commence N-acetylcysteine. I would also check LFTs, renal function, coagulation, and blood glucose. Any patient with rising ALT or coagulopathy needs urgent hepatology input.
Comprehensive psychiatric assessment: Once medically stable, I would conduct a thorough psychosocial assessment including the circumstances of the overdose, current suicidal ideation, mental state examination, psychiatric and personal history, and social circumstances. I would specifically assess intent—did he want to die? Did he expect to die? Is he disappointed to have survived?
Risk assessment: I would formulate risk by considering predisposing factors, precipitants, perpetuating factors, and protective factors. Key high-risk features would include a high-lethality method, planning, precautions against discovery, ongoing hopelessness, and lack of social support.
Management plan: Depending on risk level, I would consider psychiatric admission if risk is high. For moderate or lower risk, I would develop a collaborative safety plan, counsel on means restriction, arrange follow-up within 48-72 hours, and provide crisis contacts. I would involve family in safety planning with the patient's consent.
Documentation: I would document my assessment, risk formulation, reasoning for disposition, and the specific safety plan."
Common Mistakes in Exams
Critical Alert: ❌ Mistakes that fail candidates:
- Assuming NSSI means "not really suicidal"
- Failing to ask directly about suicidal ideation
- Using "no-suicide contracts" as a management strategy
- Discharging high-risk patients without psychiatric assessment
- Not documenting risk assessment reasoning
- Forgetting to counsel on means restriction
- Assuming that intoxicated patients cannot be assessed
- Dismissing chronic self-harmers as "attention-seeking"
- Not arranging follow-up after ED assessment
References
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Mann JJ, Apter A, Bertolote J, et al. Suicide prevention strategies: A systematic review. JAMA. 2005;294(16):2064-2074. doi:10.1001/jama.294.16.2064
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Ribeiro JD, Franklin JC, Fox KR, et al. Self-injurious thoughts and behaviors as risk factors for future suicide ideation, attempts, and death: A meta-analysis of longitudinal studies. Psychol Med. 2016;46(2):225-236. doi:10.1017/S0033291715001804
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Hawton K, Witt KG, Salisbury TLT, et al. Psychosocial interventions following self-harm in adults: A systematic review and meta-analysis. Lancet Psychiatry. 2016;3(8):740-750. doi:10.1016/S2215-0366(16)30070-0
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National Institute for Health and Care Excellence. Self-harm: Assessment, management and preventing recurrence. NICE guideline [NG225]. 2022. https://www.nice.org.uk/guidance/ng225
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Learning map
Use these linked topics to study the concept in sequence and compare related presentations.
Prerequisites
Start here if you need the foundation before this topic.
- Major Depressive Disorder
- Mental State Examination
Consequences
Complications and downstream problems to keep in mind.
- Completed Suicide
- Chronic Self-Harm Wounds