Acute Wound Dehiscence
Summary
Wound dehiscence is the separation or opening of a surgical wound after closure, which can range from superficial (skin separates) to complete (all layers separate, organs exposed). Think of a surgical wound as layers of tissue stitched together—when these layers separate, the wound opens, exposing underlying tissues or organs. This is a serious complication that can occur after any surgery, but is more common after abdominal surgery. The most common causes are infection, increased abdominal pressure (coughing, straining), poor wound healing (malnutrition, diabetes), and technical factors (poor closure technique). The key to management is recognizing the dehiscence (wound opens, may have drainage, may expose organs), assessing severity (superficial vs complete), treating infection if present (antibiotics, debridement), and surgical repair (re-closure, may need mesh if large defect). Most superficial dehiscence can be managed with wound care, but complete dehiscence with evisceration (organs exposed) is a surgical emergency requiring urgent repair.
Key Facts
- Definition: Separation or opening of surgical wound after closure
- Incidence: Common (5-10% of abdominal surgeries)
- Mortality: Low (<1%) unless complications (infection, evisceration)
- Peak age: All ages, but more common in older adults
- Critical feature: Wound opens, may expose organs
- Key investigation: Clinical diagnosis (usually obvious)
- First-line treatment: Wound care (superficial), surgical repair (complete)
Clinical Pearls
"Evisceration is an emergency" — If organs are exposed (evisceration), this is a surgical emergency. Cover with sterile dressing, keep moist, and urgent surgery.
"Infection is a common cause" — Wound infection is a leading cause of dehiscence. Always assess for infection (redness, discharge, fever).
"Increased pressure increases risk" — Anything that increases abdominal pressure (coughing, straining, vomiting) increases the risk of dehiscence. Prevent these if possible.
"Superficial vs complete matters" — Superficial dehiscence (skin only) can often be managed with wound care. Complete dehiscence (all layers) usually needs surgical repair.
Why This Matters Clinically
Wound dehiscence is a serious post-operative complication that can lead to infection, evisceration, and prolonged recovery. Early recognition, assessment for evisceration (surgical emergency), treatment of infection, and appropriate repair are essential. This is a condition that surgeons manage frequently, and prompt treatment prevents serious complications.
Incidence & Prevalence
- Overall: Common (5-10% of abdominal surgeries)
- Abdominal surgery: Most common
- Trend: Stable (common complication)
- Peak age: All ages, but more common in older adults
Demographics
| Factor | Details |
|---|---|
| Age | All ages, but more common in older adults (60+ years) |
| Sex | No significant variation |
| Ethnicity | No significant variation |
| Geography | No significant variation |
| Setting | Post-operative, surgical units |
Risk Factors
Non-Modifiable:
- Age (older = higher risk)
- Previous surgery (higher risk)
Modifiable:
| Risk Factor | Relative Risk | Mechanism |
|---|---|---|
| Infection | 5-10x | Weakens tissues |
| Malnutrition | 3-5x | Poor healing |
| Diabetes | 3-5x | Poor healing |
| Increased abdominal pressure | 3-5x | Strains wound |
| Obesity | 2-3x | Poor healing, increased pressure |
| Smoking | 2-3x | Poor healing |
Common Causes
| Cause | Frequency | Typical Patient |
|---|---|---|
| Infection | 40-50% | Wound infection |
| Increased pressure | 20-30% | Coughing, straining |
| Poor healing | 20-30% | Malnutrition, diabetes |
| Technical factors | 10-20% | Poor closure |
The Dehiscence Mechanism
Step 1: Wound Healing Compromised
- Infection: Weakens tissues
- Poor healing: Malnutrition, diabetes
- Increased pressure: Strains wound
- Result: Wound vulnerable
Step 2: Separation
- Superficial: Skin separates
- Complete: All layers separate
- Result: Wound opens
Step 3: Exposure
- Tissues exposed: Underlying tissues visible
- Organs exposed: If complete (evisceration)
- Result: Exposure
Step 4: Complications
- Infection: Risk increases
- Evisceration: Organs exposed (emergency)
- Sepsis: If infection spreads
- Result: Serious complications
Classification by Severity
| Severity | Definition | Clinical Features |
|---|---|---|
| Superficial | Skin separates | Skin opens, underlying tissues intact |
| Partial | Some layers separate | Deeper layers open |
| Complete | All layers separate | Organs exposed (evisceration) |
Anatomical Considerations
Wound Layers:
- Skin: Outermost layer
- Fascia: Deep layer (important for strength)
- Muscle: May be involved
- Peritoneum: If abdominal
Why Fascia Matters:
- Strength: Fascia provides strength
- If fascia intact: Usually superficial
- If fascia separated: Usually complete
Symptoms: The Patient's Story
Typical Presentation:
History:
Signs: What You See
Vital Signs (May Be Abnormal):
| Sign | Finding | Significance |
|---|---|---|
| Temperature | May be elevated (if infection) | Fever, infection |
| Heart rate | Usually normal (may be high if infection) | Usually normal |
| Blood pressure | Usually normal | Usually normal |
General Appearance:
Wound Examination:
| Finding | What It Means | Frequency |
|---|---|---|
| Wound open | Separation visible | Always |
| Drainage | May have discharge | Common |
| Organs visible | Evisceration (complete) | 10-20% (if complete) |
| Redness | Infection | 30-40% |
| Tenderness | Infection, inflammation | Common |
Signs of Evisceration (Critical):
Signs of Infection:
Red Flags
[!CAUTION] Red Flags — Immediate Escalation Required:
- Complete dehiscence with exposed organs — Medical emergency, needs urgent surgery
- Signs of infection — Needs urgent treatment
- Signs of evisceration — Medical emergency, needs urgent surgery
- Signs of sepsis — Medical emergency, needs urgent treatment
- Rapid progression — Needs urgent assessment
Structured Approach: ABCDE
A - Airway
- Assessment: Usually patent
- Action: Secure if compromised
B - Breathing
- Look: Usually normal
- Listen: Usually normal
- Measure: SpO2 (usually normal)
- Action: Support if needed
C - Circulation
- Look: Usually normal (may have signs of sepsis)
- Feel: Pulse (usually normal), BP (usually normal)
- Listen: Heart sounds (usually normal)
- Measure: BP (usually normal), HR
- Action: Monitor if sepsis
D - Disability
- Assessment: Usually normal
- Action: Assess if severe
E - Exposure
- Look: Wound examination
- Feel: Tenderness, assess depth
- Action: Complete examination
Specific Examination Findings
Wound Examination:
- Inspection:
- Open: Wound open
- Depth: Assess depth (superficial vs complete)
- Organs: Check for evisceration
- Drainage: Check for discharge
- Palpation:
- Tenderness: Painful
- Depth: Feel depth of separation
- Measure: Size of defect
Assess for Evisceration:
- Look: Organs visible?
- Action: If yes, urgent surgery
Assess for Infection:
- Look: Redness, discharge
- Feel: Warmth, tenderness
- Action: If yes, treat infection
Special Tests
| Test | Technique | Positive Finding | Clinical Use |
|---|---|---|---|
| Wound swab | Swab wound | May be positive | Identifies infection |
| Blood cultures | Blood test | May be positive | If systemic infection |
First-Line (Bedside) - Do Immediately
1. Clinical Diagnosis (Usually Obvious)
- History: Recent surgery, wound opening
- Examination: Wound open, assess severity
- Action: Usually sufficient for diagnosis
2. Assess for Evisceration (Critical)
- Look: Organs visible?
- Action: Urgent surgery if yes
Laboratory Tests
| Test | Expected Finding | Purpose |
|---|---|---|
| Full Blood Count | May show leukocytosis (if infection) | Identifies infection |
| CRP | May be elevated (if infection) | Identifies infection |
| Wound swab | May be positive | Identifies pathogen |
Imaging
Usually not needed — Clinical diagnosis is usually sufficient.
CT (If Uncertain or Complications):
| Indication | Finding | Clinical Note |
|---|---|---|
| Uncertain extent | May show extent | If needed |
Diagnostic Criteria
Clinical Diagnosis:
- Recent surgery + wound opens = Wound dehiscence
Severity Assessment:
- Superficial: Skin only
- Partial: Some layers
- Complete: All layers, organs exposed (evisceration)
Management Algorithm
WOUND DEHISCENCE PRESENTATION
(Recent surgery + wound opens)
↓
┌─────────────────────────────────────────────────┐
│ ASSESS SEVERITY │
│ • Superficial (skin only) │
│ • Partial (some layers) │
│ • Complete (all layers, organs exposed) │
└─────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────┐
│ EVISCERATION? │
├─────────────────────────────────────────────────┤
│ YES (ORGANS EXPOSED) │
│ → Cover with sterile dressing, keep moist │
│ → Urgent surgery (within hours) │
│ → Re-close wound │
│ │
│ NO (NO ORGANS EXPOSED) │
│ → Assess for infection │
│ → Treat infection if present │
│ → Wound care or surgical repair │
└─────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────┐
│ TREAT INFECTION (IF PRESENT) │
│ • Antibiotics │
│ • Debridement if needed │
└─────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────┐
│ REPAIR │
├─────────────────────────────────────────────────┤
│ SUPERFICIAL │
│ → Wound care (dressings, may heal by secondary intention) │
│ │
│ PARTIAL/COMPLETE │
│ → Surgical repair (re-close, may need mesh) │
└─────────────────────────────────────────────────┘
↓
┌─────────────────────────────────────────────────┐
│ PREVENT RECURRENCE │
│ • Treat underlying causes (infection, malnutrition) │
│ • Prevent increased pressure │
│ • Support healing │
└─────────────────────────────────────────────────┘
Acute/Emergency Management - The First Hour
Immediate Actions (Do Simultaneously):
-
Assess for Evisceration (Critical)
- Look: Organs visible?
- Action: If yes, cover with sterile dressing, keep moist, urgent surgery
-
Assess Severity
- Examination: Superficial vs complete
- Action: Determine treatment
-
Assess for Infection
- Signs: Redness, discharge, fever
- Action: Treat if present
-
Surgical Consultation (If Complete or Evisceration)
- Urgent: If evisceration (within hours)
- Urgent: If complete (within 24 hours)
- Action: Don't delay
-
Wound Care (If Superficial)
- Dressings: Appropriate dressings
- Action: May heal with wound care
Medical Management
Antibiotics (If Infection):
| Drug | Dose | Route | Duration | Notes |
|---|---|---|---|---|
| Co-amoxiclav | 1.2g | IV | TDS | If infection |
| Metronidazole | 500mg | IV | TDS | Add if abdominal |
Wound Care (Superficial):
- Dressings: Appropriate dressings
- May heal: By secondary intention
- Action: Support healing
Surgical Management
Surgical Repair (If Complete or Evisceration):
| Procedure | Indication | Notes |
|---|---|---|
| Re-closure | If clean, no infection | Primary closure |
| Mesh repair | If large defect | May need mesh |
| Debridement | If infection | Remove infected tissue |
Timing:
- Evisceration: Urgent (within hours)
- Complete: Urgent (within 24 hours)
Disposition
Admit to Hospital:
- All cases: Need monitoring, treatment
- Evisceration: Urgent surgery
- Complete: Urgent surgery
Discharge Criteria:
- Stable: Wound managed
- No complications: No complications
- Clear plan: For continued care, follow-up
Follow-Up:
- Wound: Monitor healing
- Recovery: Usually recovers
- Long-term: Usually no long-term issues
Immediate (Days-Weeks)
| Complication | Incidence | Presentation | Management |
|---|---|---|---|
| Infection | 20-30% | Redness, discharge, fever | Antibiotics, debridement |
| Evisceration | 10-20% (if complete) | Organs exposed | Urgent surgery |
| Sepsis | 5-10% (if infection) | Fever, tachycardia, hypotension | IV antibiotics, supportive care |
| Re-dehiscence | 10-20% | Wound opens again | May need further surgery |
Infection:
- Mechanism: Wound exposed, bacteria enter
- Management: Antibiotics, debridement
- Prevention: Prevent dehiscence, treat early
Early (Weeks-Months)
1. Usually Full Recovery (80-90%)
- Mechanism: Most heal with treatment
- Management: Usually no long-term treatment needed
- Prevention: Appropriate treatment
2. Chronic Wound (5-10%)
- Mechanism: Wound doesn't heal
- Management: Ongoing wound care, may need further surgery
- Prevention: Appropriate treatment, address underlying causes
Late (Months-Years)
1. Usually No Long-Term Issues (90-95%)
- Mechanism: Most recover completely
- Management: Usually no long-term treatment needed
- Prevention: N/A
Natural History (Without Treatment)
Untreated Wound Dehiscence:
- Infection: High risk
- Evisceration: High risk if complete
- Poor outcomes: If not treated
Outcomes with Treatment
| Variable | Outcome | Notes |
|---|---|---|
| Recovery | 80-90% | Most heal with treatment |
| Mortality | <1% | Very low with prompt treatment |
| Re-dehiscence | 10-20% | May recur |
| Time to recovery | Weeks to months | With treatment |
Factors Affecting Outcomes:
Good Prognosis:
- Early treatment: Better outcomes
- Superficial: Usually heals well
- No infection: Better outcomes
- Good nutrition: Better healing
Poor Prognosis:
- Delayed treatment: Higher risk of complications
- Complete dehiscence: Longer recovery
- Infection: Worse outcomes
- Poor nutrition: Poor healing
Prognostic Factors
| Factor | Impact on Prognosis | Evidence Level |
|---|---|---|
| Early treatment | Better outcomes | High |
| Severity | Superficial = better | High |
| Infection | No infection = better | High |
| Nutrition | Good nutrition = better | Moderate |
Key Guidelines
1. NICE Guidelines (2019) — Surgical site infections: prevention and treatment. National Institute for Health and Care Excellence
Key Recommendations:
- Prevent infection
- Treat infection early
- Evidence Level: 1A
Landmark Trials
Multiple studies on wound care, surgical repair techniques.
Evidence Strength
| Intervention | Level | Key Evidence | Clinical Recommendation |
|---|---|---|---|
| Urgent surgery (evisceration) | 1A | Universal | Essential |
| Treat infection | 1A | Multiple studies | Essential |
| Wound care (superficial) | 1A | Multiple studies | Usually sufficient |
What is Wound Dehiscence?
Wound dehiscence is when a surgical wound opens or separates after it was closed. Think of a surgical wound as layers of tissue stitched together—when these layers separate, the wound opens, exposing underlying tissues or organs. This is a serious complication that can occur after surgery.
In simple terms: Your surgical wound has opened. This is serious, but with proper treatment, most wounds heal well.
Why does it matter?
Wound dehiscence is a serious post-operative complication that can lead to infection, evisceration (organs exposed), and prolonged recovery. Early recognition and appropriate treatment are essential. The good news? With prompt treatment, most wounds heal well.
Think of it like this: It's like a wound coming apart—it needs to be fixed, but once it's fixed, most people recover well.
How is it treated?
1. Assessment:
- Examination: Your doctor will examine the wound to see how serious it is
- Why: To see if it's just the skin (superficial) or deeper (complete, may expose organs)
2. If Organs Exposed (Evisceration):
- Urgent surgery: You'll need urgent surgery to put the organs back and close the wound
- When: Usually within hours
- Why: This is a medical emergency
3. If No Organs Exposed:
- If superficial: You'll get wound care (dressings) and the wound may heal on its own
- If deeper: You'll need surgery to re-close the wound
- If infection: You'll get antibiotics
4. Prevent Recurrence:
- Treat causes: Your doctor will treat any underlying causes (infection, malnutrition)
- Prevent pressure: Avoid things that increase pressure (coughing, straining)
- Support healing: Good nutrition, wound care
The goal: Close the wound, treat any infection, and help it heal properly.
What to expect
Recovery:
- Superficial: Usually heals within weeks with wound care
- Complete: Usually needs surgery, recovery takes longer
- Full recovery: Most people recover completely
After Treatment:
- Wound care: You'll need regular wound care
- Surgery: If you had surgery, you'll recover from that
- Monitoring: Your doctor will monitor to make sure it's healing
- Follow-up: Regular follow-up to monitor healing
Recovery Time:
- Superficial: Usually weeks
- Complete: Usually weeks to months
When to seek help
Call 999 (or your emergency number) immediately if:
- Your surgical wound has opened and you can see organs inside
- Your surgical wound has opened and you feel very unwell
- Your surgical wound has opened and you have a high fever
See your doctor if:
- Your surgical wound has opened
- Your surgical wound has increased drainage
- Your surgical wound is red, painful, or has discharge
- You have concerns about your surgical wound
Remember: If your surgical wound has opened, especially if you can see organs inside, call 999 immediately. Wound dehiscence is serious, but with prompt treatment, most wounds heal well. Don't delay—if you're worried, seek help immediately.
Primary Guidelines
- National Institute for Health and Care Excellence. Surgical site infections: prevention and treatment. NICE guideline [NG125]. 2019.
Key Trials
- Multiple studies on wound care, surgical repair techniques.
Further Resources
- NICE Guidelines: National Institute for Health and Care Excellence
Last Reviewed: 2025-12-25 | MedVellum Editorial Team
Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. Clinical decisions should account for individual patient circumstances. Always consult appropriate specialists. This information is not a substitute for professional medical advice, diagnosis, or treatment.