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Anion Gap: How to Use It Properly

Built to support a MedVellum short or longer explainer on acid-base reasoning, then route people directly into the calculator and related topics.

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Key takeaways

  • A “normal” anion gap can be misleading when albumin is low.
  • The number only becomes clinically useful once paired with lactate, ketones, renal function, and the bedside story.
  • Use the tool page for the quick calculation and the linked topics for the why.

Linked topics

Acute poisoning

Toxidrome-linked high-anion-gap acidosis causes.

Hyperosmolar hyperglycaemic state

One of the common metabolic derangement frameworks.

Linked tools

Anion gap calculator

Fast bedside calculation with albumin correction context.