Overview
Acute Low Back Pain
Quick Reference
Critical Alerts
- Cauda equina syndrome is a surgical emergency: Saddle anesthesia, urinary retention, bilateral weakness
- Red flags require urgent evaluation: Cancer, infection, fracture, neurological deficit
- Most low back pain is benign and self-limited: 90% resolve within 6 weeks
- Imaging rarely changes management initially: Reserve for red flags
- Early mobilization improves outcomes: Avoid prolonged bed rest
- Opioids should be avoided or used short-term only
Red Flags (TUNA FISH)
| Letter | Red Flag |
|---|---|
| T | Trauma |
| U | Unexplained weight loss |
| N | Neurological deficit (bladder/bowel, weakness) |
| A | Age >0 (new onset) or <18 |
| F | Fever, IV drug use, recent infection |
| I | Immunocompromise |
| S | Steroid use (osteoporosis risk) |
| H | History of cancer |
Cauda Equina Syndrome Warning Signs
| Finding | Action |
|---|---|
| Saddle anesthesia | Emergent MRI, neurosurgery |
| Urinary retention or incontinence | Emergent MRI, neurosurgery |
| Fecal incontinence | Emergent MRI, neurosurgery |
| Bilateral leg weakness | Emergent MRI, neurosurgery |
| Rapidly progressive neurological deficit | Emergent MRI, neurosurgery |
Emergency Treatments
| Condition | Treatment |
|---|---|
| Mechanical LBP | NSAIDs + activity modification + PT referral |
| Radiculopathy (no red flags) | NSAIDs + activity + PT; consider oral steroids |
| Cauda equina syndrome | Emergent MRI → Surgical decompression |
| Spinal infection (epidural abscess) | MRI + IV antibiotics + surgical consult |
| Metastatic spinal cord compression | MRI + steroids + oncology/neurosurgery |
Definition
Overview
Acute low back pain (LBP) is pain in the lumbosacral region lasting less than 4 weeks. It is one of the most common reasons for ED visits and physician consultation. The key ED task is identifying the rare serious causes (cauda equina, cancer, infection, fracture) while appropriately managing the majority with reassurance, analgesia, and activity.
Classification
By Duration:
| Type | Duration |
|---|---|
| Acute | <4 weeks |
| Subacute | 4-12 weeks |
| Chronic | >2 weeks |
By Cause:
| Type | Frequency | Examples |
|---|---|---|
| Mechanical (non-specific) | ~85% | Muscle strain, ligament sprain, degenerative |
| Radiculopathy | ~5-10% | Herniated disc, stenosis |
| Serious pathology | <5% | Cauda equina, cancer, infection, fracture |
Epidemiology
- Lifetime prevalence: 70-80%
- Leading cause of disability worldwide
- Peak age: 30-50 years
- Recurrence common: ~25-50%
Etiology
Mechanical/Non-Specific (~85%):
| Cause | Notes |
|---|---|
| Muscle strain | Most common |
| Ligament sprain | Lifting, twisting |
| Degenerative disc/joint disease | Older adults |
| Spondylolisthesis | Young athletes (pars defect) |
Radiculopathy/Sciatica (~5-10%):
| Cause | Mechanism |
|---|---|
| Herniated disc | Nerve root compression |
| Spinal stenosis | Neurogenic claudication |
Serious Pathology (<5%):
| Cause | Red Flags |
|---|---|
| Cauda equina syndrome | Saddle anesthesia, retention, bilateral symptoms |
| Malignancy | Weight loss, history of cancer |
| Spinal infection (epidural abscess, discitis) | Fever, IVDU, immunocompromise |
| Fracture | Trauma, osteoporosis, steroids |
| Abdominal aortic aneurysm | Pulsatile mass, hypotension |
4. Pathophysiology
Mechanical LBP
- Microtrauma to muscles, ligaments, discs
- Inflammatory response → Pain, spasm
- Usually self-limited
Radiculopathy
- Herniated disc or bony stenosis compresses nerve root
- L4-L5 and L5-S1 most common levels
- Dermatomal pain, sensory/motor deficits
Cauda Equina Syndrome
- Compression of cauda equina (nerve roots below conus)
- Causes: Large disc herniation, tumor, abscess, hematoma
- Results in bladder/bowel dysfunction, saddle anesthesia, weakness
5. Clinical Presentation
Symptoms
| Finding | Mechanical LBP | Radiculopathy | Cauda Equina |
|---|---|---|---|
| Pain distribution | Localized low back | Radiates below knee (dermatomal) | Bilateral leg pain |
| Neurological symptoms | None | Sensory, motor (dermatomal) | Saddle anesthesia, bladder/bowel |
| Onset | Usually after activity | May be gradual or sudden | Usually rapid |
History
Key Questions:
Physical Examination
General Exam:
| Finding | Significance |
|---|---|
| Fever | Infection |
| Weight loss | Malignancy |
| Pulsatile abdominal mass | AAA |
Spine Exam:
| Finding | Significance |
|---|---|
| Midline tenderness | Fracture, infection |
| Paraspinal muscle spasm | Mechanical |
| Limited range of motion | Mechanical or serious |
| Step-off deformity | Spondylolisthesis |
Neurological Exam:
| Test | Level | Finding |
|---|---|---|
| Knee reflex (L4) | L4 | Diminished = L4 radiculopathy |
| Ankle reflex (S1) | S1 | Diminished = S1 radiculopathy |
| Great toe dorsiflexion (L5) | L5 | Weak = L5 radiculopathy |
| Straight leg raise (SLR) | Sciatic | Positive = Radiculopathy |
| Perianal sensation | S2-S4 | Absent = Cauda equina |
| Rectal tone | S2-S4 | Decreased = Cauda equina |
Straight Leg Raise:
Onset, duration, character, radiation of pain
Common presentation.
Trauma?
Common presentation.
Red flag symptoms (weight loss, fever, bladder/bowel changes, weakness)
Common presentation.
History of cancer?
Common presentation.
IV drug use, recent infection?
Common presentation.
Steroid use, immunocompromise?
Common presentation.
Previous spinal surgery or injections?
Common presentation.
6. Clinical Examination
(Integrated into Clinical Presentation above)
Red Flags
Must Exclude Serious Pathology
| Red Flag | Concern | Action |
|---|---|---|
| Saddle anesthesia | Cauda equina | Emergent MRI |
| Urinary retention/incontinence | Cauda equina | Emergent MRI |
| Bilateral leg weakness | Cauda equina | Emergent MRI |
| Fever | Epidural abscess, discitis | MRI, blood cultures |
| IVDU, recent infection | Epidural abscess | MRI |
| History of cancer | Metastatic disease | MRI, oncology |
| Unexplained weight loss | Malignancy | MRI |
| Age >0 with new LBP | Malignancy, fracture | Consider imaging |
| Severe trauma | Fracture | X-ray/CT |
| Steroid use, osteoporosis | Fracture | X-ray |
| Progressive neurological deficit | Cord/root compression | MRI |
7. Investigations
Differential Diagnosis
| Diagnosis | Features |
|---|---|
| Renal colic | Colicky flank pain, hematuria |
| Pyelonephritis | Fever, CVA tenderness, pyuria |
| Abdominal aortic aneurysm | Pulsatile mass, hypotension (if ruptured) |
| Pancreatitis | Epigastric pain radiating to back |
| GI pathology | Associated with eating, bowel symptoms |
| Hip pathology | Groin/lateral pain, limited hip ROM |
| Herpes zoster | Dermatomal rash, pain precedes rash |
Diagnostic Approach
Imaging Guidelines
Imaging NOT Indicated for Most Acute LBP:
- No red flags = No imaging initially
- Most acute LBP resolves in 4-6 weeks
When to Image:
| Indication | Modality |
|---|---|
| Red flags (cauda equina, cancer, infection) | MRI |
| Severe trauma, fracture concern | X-ray → CT if positive or high suspicion |
| Progressive neurological deficit | MRI |
| Not improving after 6 weeks of conservative care | MRI |
Laboratory Studies
| Test | Indication |
|---|---|
| CBC, ESR, CRP | Suspected infection or malignancy |
| Blood cultures | Suspected epidural abscess |
| Urinalysis | Rule out renal pathology |
8. Management
Principles
- Reassurance: Most LBP is benign and self-limited
- Activity: Early mobilization; avoid bed rest
- Analgesia: NSAIDs first-line; avoid opioids if possible
- Physical therapy: Referral for subacute/chronic cases
- Identify and emergently treat red flags
Analgesia
First-Line: NSAIDs:
| Agent | Dose |
|---|---|
| Ibuprofen | 400-600 mg PO TID |
| Naproxen | 500 mg PO BID |
Adjuncts:
| Agent | Notes |
|---|---|
| Acetaminophen | Less effective than NSAIDs but useful |
| Muscle relaxants (short-term) | Cyclobenzaprine 10 mg TID; sedating |
| Topical analgesics | Lidocaine patch, diclofenac gel |
Avoid/Minimize:
| Agent | Reason |
|---|---|
| Opioids | No long-term benefit; addiction risk |
| Benzodiazepines | No evidence; sedation, dependence |
| Systemic steroids | No benefit for non-radicular LBP |
Radiculopathy Management
| Intervention | Details |
|---|---|
| NSAIDs | First-line |
| Activity modification | Avoid aggravating activities |
| Physical therapy | Core strengthening, stretching |
| Oral steroids (short course) | May provide short-term relief |
| Epidural steroid injection | For refractory radiculopathy (specialist) |
| Surgery | For progressive neurological deficit or failure of conservative management |
Cauda Equina Syndrome
| Intervention | Details |
|---|---|
| Emergent MRI | Confirm diagnosis |
| Neurosurgical consultation | Urgent |
| Surgical decompression | Within 24-48 hours (ideally sooner) |
Spinal Infection (Epidural Abscess, Discitis)
| Intervention | Details |
|---|---|
| MRI | Imaging of choice |
| Blood cultures | Before antibiotics if possible |
| IV antibiotics | Broad-spectrum (staph coverage: vancomycin + cefepime or pip-tazo) |
| Surgical drainage | If abscess, neurological deficit, or instability |
Metastatic Spinal Cord Compression
| Intervention | Details |
|---|---|
| MRI whole spine | Identify all metastases |
| Dexamethasone | 10 mg IV bolus → 4 mg q6h |
| Oncology/Radiation oncology | Urgent |
| Neurosurgery | If surgical candidate |
9. Complications
Disposition
Discharge Criteria
- No red flags
- Pain controlled
- Able to ambulate
- Reliable follow-up
Admission Criteria
- Cauda equina syndrome
- Epidural abscess
- Metastatic spinal cord compression
- Unstable spinal fracture
- Unable to ambulate or care for self
- Severe pain not controlled
Referral
| Indication | Referral |
|---|---|
| Radiculopathy not improving | Spine surgery or PM&R |
| Chronic LBP | Pain management, physical therapy |
| Suspected malignancy | Oncology |
Follow-Up
| Situation | Follow-Up |
|---|---|
| Mechanical LBP | PCP in 1-2 weeks if not improving |
| Radiculopathy | Specialist within 1-2 weeks |
| Post-hospitalization | Spine surgery/oncology as indicated |
12. Patient/Layperson Explanation
Condition Explanation
- "Low back pain is very common and usually not serious."
- "Most cases improve within a few weeks with activity and medication."
- "Staying active is better than bed rest."
Home Care
- Use NSAIDs as directed
- Apply ice or heat for comfort
- Stay active; gentle walking and stretching
- Avoid lifting heavy objects
- Maintain good posture
Warning Signs to Return
- Numbness in groin or inner thighs (saddle area)
- Difficulty urinating or loss of bowel control
- Weakness in legs or feet getting worse
- Fever or chills
- Unexplained weight loss
10. Prognosis & Outcomes
Special Populations
Elderly
- Higher risk of serious pathology (cancer, fracture)
- Lower threshold for imaging
- More cautious with NSAIDs (renal, GI, CV risk)
Cancer History
- Any new LBP is metastatic disease until proven otherwise
- MRI of entire spine
Osteoporosis/Steroid Use
- Vertebral compression fractures
- X-ray initially; MRI if neurological symptoms
Pregnancy
- Avoid NSAIDs (especially 3rd trimester)
- Acetaminophen for analgesia
- Physical therapy helpful
Quality Metrics
Performance Indicators
| Metric | Target | Rationale |
|---|---|---|
| Red flag documentation | 100% | Identify serious causes |
| Neurological exam documented | 100% | Detect cauda equina |
| Avoid imaging without red flags | >0% | Reduce unnecessary radiation |
| NSAIDs as first-line | >0% | Guideline adherence |
| Avoid opioids for acute LBP | >0% | Prevent opioid misuse |
Documentation Requirements
- Red flag assessment
- Neurological exam (strength, reflexes, sensation)
- Rectal tone and saddle sensation (if cauda equina suspected)
- Imaging rationale (if performed)
- Discharge instructions
11. Evidence & Guidelines
Key Clinical Pearls
Diagnostic Pearls
- Cauda equina = Emergent MRI: Don't miss bladder/bowel symptoms
- Red flags guide imaging: Most acute LBP doesn't need imaging
- SLR is sensitive for radiculopathy: Crossed SLR is more specific
- Check perianal sensation and rectal tone: For cauda equina
- Age >50 + new LBP: Consider malignancy/fracture
- IVDU + back pain + fever = Epidural abscess: MRI urgently
Treatment Pearls
- NSAIDs are first-line: Better than acetaminophen alone
- Muscle relaxants are adjuncts: Short-term only; sedating
- Avoid opioids: No long-term benefit; addiction risk
- Early activity is key: Bed rest worsens outcomes
- Steroids only for radiculopathy: Not for mechanical LBP
- PT referral for subacute/chronic: Core strengthening
Disposition Pearls
- Most can be discharged: With reassurance and analgesia
- Admit for red flags: Cauda equina, abscess, cancer
- Follow-up in 1-2 weeks: If not improving
- Specialist for radiculopathy not improving: 4-6 weeks
13. References
- Qaseem A, et al. Noninvasive Treatments for Acute, Subacute, and Chronic Low Back Pain. Ann Intern Med. 2017;166(7):514-530.
- Chou R, et al. Diagnosis and Treatment of Low Back Pain: A Joint Clinical Practice Guideline. Ann Intern Med. 2007;147(7):478-491.
- Deyo RA, et al. Low Back Pain. N Engl J Med. 2001;344(5):363-370.
- Jarvik JG, et al. Diagnostic imaging for low back pain. Ann Intern Med. 2002;137(7):586-597.
- Kreiner DS, et al. An evidence-based clinical guideline for the diagnosis and treatment of lumbar disc herniation with radiculopathy. Spine J. 2014;14(1):180-191.
- Casazza BA. Diagnosis and treatment of acute low back pain. Am Fam Physician. 2012;85(4):343-350.
- NICE Guideline. Low back pain and sciatica in over 16s: assessment and management. 2016.
- UpToDate. Evaluation of low back pain in adults. 2024.