Extradural Haemorrhage (EDH)
Summary
Extradural Haemorrhage (EDH) is an arterial bleed (Most commonly from the Middle Meningeal Artery) located between the skull and the dura mater. It typically follows trauma (Blow to the temporal region – Pterion). The haematoma does NOT cross suture lines (Dura is adherent). On CT, it appears as a biconvex ("Lemon-shaped") hyperdense collection. The classic presentation is the "Lucid Interval" – Initial loss of consciousness -> Apparent recovery -> Rapid deterioration and death as the haematoma expands and causes uncal herniation (Compression of CN III leading to ipsilateral dilated pupil, then brainstem compression). This is a neurosurgical emergency; emergency craniotomy and evacuation is life-saving. Prognosis is excellent if treated before herniation ("Talk and Die" syndrome occurs when recognition is delayed).
Key Facts
- Location: Between Skull and Dura Mater.
- Aetiology: Trauma to Pterion (Temporoparietal).
- Vessel: Middle Meningeal Artery (Most common). Venous (Rarer, often posterior fossa).
- CT Appearance: Biconvex (Lemon-shaped). Hyperdense. Does NOT cross suture lines.
- Lucid Interval: "Talk and Die" – Initial LOC -> Recovery -> Deterioration.
- Herniation Signs: Ipsilateral Fixed Dilated Pupil (CN III), Contralateral Hemiparesis, Cushing's Triad.
- Treatment: Emergency Craniotomy and Evacuation.
Clinical Pearls
"Lemon Shape = Extradural": Biconvex. Subdural is crescent-shaped.
"Lucid Interval = High Index of Suspicion": Patient who was knocked out, wakes up, then deteriorates rapidly.
"Blown Pupil = Ipsilateral to Lesion": CN III compressed against tentorium.
"Does NOT Cross Sutures": Dura is adherent at suture lines.
Why This Matters Clinically
EDH is one of the most treatable neurosurgical emergencies. Prompt recognition and surgery can result in complete recovery; delay leads to death.
Incidence
- 1-4% of Head Injuries.
- Peak Age: Young adults (20-30 years). Trauma-prone.
- Rare in Infants/Elderly: Dura more adherent to skull at extremes of age.
- Mortality: ~5-10% if treated. ~90%+ if untreated/delayed.
Pterion
| Feature | Notes |
|---|---|
| Location | Temple region. Junction of Frontal, Parietal, Temporal, Sphenoid bones. |
| Weakness | Thinnest part of skull. Overlies Middle Meningeal Artery. |
| Trauma | Blow to temple -> Skull fracture -> MMA laceration -> EDH. |
Middle Meningeal Artery (MMA)
| Feature | Notes |
|---|---|
| Origin | Branch of Maxillary Artery (ECA). |
| Course | Enters skull via Foramen Spinosum. Runs in groove on inner skull. |
| Significance | Arterial bleeding -> Rapid accumulation of blood. |
Haematoma Formation
- Stripping of dura from skull as blood accumulates.
- Dura adherent at suture lines -> Biconvex shape. Does NOT cross sutures.
- Volume increases rapidly (Arterial).
- Mass effect -> Raised ICP -> Herniation.
Uncal Herniation
| Stage | Pathology | Clinical Sign |
|---|---|---|
| 1 | Uncus of temporal lobe compresses CN III. | Ipsilateral dilated pupil (Parasympathetic fibres first). |
| 2 | Cerebral peduncle compressed against tentorium. | Contralateral hemiparesis (Ipsilateral false localising if Kernohan's notch). |
| 3 | Brainstem compression. | Cushing's Triad. Coma. Death. |
Cushing's Triad (Late Sign of Raised ICP)
| Feature | Notes |
|---|---|
| Hypertension | Reflex to maintain cerebral perfusion. |
| Bradycardia | Baroreceptor response. |
| Irregular Respiration (Cheyne-Stokes) | Brainstem dysfunction. |
Classic "Lucid Interval"
| Phase | Description |
|---|---|
| Initial Impact | Loss of Consciousness (Brief). |
| Lucid Interval | Recovery. Alert. May appear well. (Minutes to Hours). |
| Deterioration | Headache. Vomiting. Confusion. Seizures. GCS falls. Pupil dilates. Death. |
Lucid interval is classic but NOT always present.
Symptoms
| Symptom | Notes |
|---|---|
| Headache | Worsening. |
| Nausea / Vomiting | Raised ICP. |
| Confusion / Altered Consciousness | |
| Seizures |
Signs
| Sign | Notes |
|---|---|
| GCS Decline | Progressive. |
| Ipsilateral Dilated Pupil | CN III compression. Fixed and unreactive ("Blown"). |
| Contralateral Hemiparesis | Cerebral peduncle compression. |
| Cushing's Triad | Late. Ominous. |
| Scalp Injury / Haematoma | Over temple (Pterion). |
CT Head (Non-Contrast) – URGENT
| Finding | Description |
|---|---|
| Biconvex (Lentiform) Collection | "Lemon-shaped". High density (Acute blood). |
| Does NOT Cross Suture Lines | Dura adherent at sutures. |
| Mass Effect | Midline shift. Compression of lateral ventricle. |
| Skull Fracture | Often overlying temporal bone. |
Comparison: EDH vs SDH
| Feature | EDH (Extradural) | SDH (Subdural) |
|---|---|---|
| Shape | Biconvex (Lemon). | Crescent (Banana). |
| Suture Lines | Does NOT cross. | DOES cross. |
| Location | Between Skull and Dura. | Between Dura and Arachnoid. |
| Aetiology | Arterial (MMA). Trauma. | Venous (Bridging veins). Trauma. Elderly. |
| Speed | Rapid accumulation. | Slower (Acute, Subacute, Chronic). |
Principles (EMERGENCY)
- ABCDE Approach (Trauma resuscitation).
- Avoid Secondary Brain Injury (Maintain BP, Oxygenation, Normoglycaemia).
- Urgent CT Head.
- Emergency Neurosurgery (Craniotomy).
- Post-Op ICU Care.
Pre-Hospital / A&E
| Intervention | Detail |
|---|---|
| Airway | Protect. Intubate if GCS ≤8. |
| Breathing | Oxygenate. Avoid hypoxia. |
| Circulation | Avoid hypotension (SBP >0). |
| GCS Monitoring | Frequent. Document changes. |
| Urgent Transfer | To Neurosurgical centre. |
Medical Measures (Bridge to Surgery)
| Measure | Detail |
|---|---|
| Head Elevation | 30 degrees (If spine cleared). |
| IV Mannitol (Or Hypertonic Saline) | Reduce ICP temporarily. |
| Anti-Epileptics | If seizures. |
| Avoid Hyperthermia |
Surgical Management
| Procedure | Detail |
|---|---|
| Craniotomy | Bone flap raised. Haematoma evacuated. MMA cauterised/ligated. |
| Burr Holes | May be used as emergency drainage (If delay to craniotomy). |
Indications for Surgery (NICE/SBNS)
| Indication | Notes |
|---|---|
| EDH >0ml | |
| Thickness >5mm | |
| Midline Shift >mm | |
| GCS <9 with pupil asymmetry | |
| Any symptomatic / deteriorating patient |
Conservative management may be appropriate for small EDH (<30ml, <15mm, No shift, GCS 15) with close observation and repeat imaging.
| Complication | Notes |
|---|---|
| Uncal Herniation | Death if untreated. |
| Brain Death | |
| Seizures | |
| Post-Operative Infection | Meningitis. Abscess. |
| Re-Accumulation | |
| Neurological Deficit | If delayed treatment. |
| Scenario | Outcome |
|---|---|
| Early Surgery (Before Herniation) | Excellent. Near-complete recovery expected. |
| Delayed Surgery / Post-Herniation | High mortality / Significant disability. |
| "Talk and Die" | Patients who deteriorate after initial lucidity – Highlights need for vigilance. |
| Condition | Distinguishing Features |
|---|---|
| Subdural Haematoma (SDH) | Crescent-shaped. Crosses sutures. Slower. Elderly. |
| Subarachnoid Haemorrhage (SAH) | "Thunderclap" headache. Starfish pattern. Aneurysm. |
| Intracerebral Haemorrhage (ICH) | Hypertension. Intraparenchymal blood. |
| Contusion | Bruising of brain parenchyma. |
| Diffuse Axonal Injury (DAI) | Shearing. Multiple small haemorrhages. |
Key Guidelines
| Guideline | Organisation | Notes |
|---|---|---|
| NICE NG232 | NICE | Head Injury: Assessment and Early Management. |
| SBNS | Society of British Neurological Surgeons | Indications for surgery. |
Scenario 1:
- Stem: A young man is hit on the side of the head. He was briefly unconscious, then fully recovered (Lucid interval), then suddenly becomes unresponsive with a fixed dilated left pupil. CT shows a biconvex hyperdense lesion. What is the diagnosis and immediate management?
- Answer: Extradural Haemorrhage. Emergency Craniotomy and Evacuation.
Scenario 2:
- Stem: What vessel is most commonly injured in EDH?
- Answer: Middle Meningeal Artery.
Scenario 3:
- Stem: What is the CT appearance of an EDH, and why does it NOT cross suture lines?
- Answer: Biconvex (Lemon-shaped) collection. Does NOT cross sutures because the dura is adherent to the skull at suture lines.
| Scenario | Urgency | Action |
|---|---|---|
| Any suspected EDH | Emergency | Urgent CT Head. Neurosurgery referral. |
| GCS Decline / Pupil Changes | Emergency | Resuscitate. Transfer to Neurosurgical centre. |
| Small EDH, GCS 15, Stable | Urgent | Neurosurgery opinion. Admit. Observe. Repeat CT. |
What is an Extradural Haemorrhage?
An extradural haemorrhage is bleeding between the skull and the brain's covering (dura) after a head injury. It is usually caused by damage to a blood vessel in the temple area.
Why is it dangerous?
Blood builds up quickly and presses on the brain. This can cause unconsciousness, brain damage, and death if not treated urgently.
What is the "Lucid Interval"?
Someone may be knocked out briefly, wake up and seem fine, then suddenly get much worse as the bleeding expands. This is a warning sign – seek help immediately if this occurs.
How is it treated?
- Emergency surgery to remove the blood and stop the bleeding.
Key Counselling Points (Post-Operative)
- Follow-Up: "You will need monitoring and follow-up imaging."
- Warning Signs: "Report any new headaches, confusion, or weakness."
- Recovery: "With prompt treatment, most people make a full recovery."
| Standard | Target |
|---|---|
| CT Head within 1 hour of presentation for GCS <15 | 100% |
| Neurosurgery referral within 1 hour of CT diagnosis | 100% |
| Time to surgery <4 hours for surgical EDH | >0% |
- William Macewen (1879): Pioneer of surgical evacuation for intracranial haematomas.
- Harvey Cushing: Advanced understanding of raised ICP and herniation syndromes.
- NICE NG232. Head Injury: Assessment and Early Management. nice.org.uk
- Bullock MR, et al. Surgical Management of Traumatic Brain Injury. Neurosurgery. 2006.
Last Reviewed: 2025-12-24 | MedVellum Editorial Team
Medical Disclaimer: MedVellum content is for educational purposes and clinical reference. Head injury is a medical emergency – seek immediate medical attention.